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The map label for this gene is gltT [H]

Identifier: 49184357

GI number: 49184357

Start: 1373442

End: 1373987

Strand: Direct

Name: gltT [H]

Synonym: BAS1340

Alternate gene names: 49184357

Gene position: 1373442-1373987 (Clockwise)

Preceding gene: 49184355

Following gene: 49184358

Centisome position: 26.27

GC content: 35.53

Gene sequence:

>546_bases
ATGAAAAGAATAGGACTTGCATGGCAAATATTAATAGGACTTGCGCTTGGTATTGCAGTTGGGGCGATTTTCTTTGATAA
TCCAGCGGTTGTGAAATATTTACAACCAATTGGTGATATTTTCATCCGATTAATTAAAATGATCGTTGTACCGATTGTTG
TAGCAAGTATTGTTGTTGGGGTTGCTGGTGTTGGTGATGTTAAAAAATTAGGCCGACTAGGCGGAAAAACAATTATTTAC
TTTGAAATTATTACAACAATTGCAATTATTGTCGGTCTATTAATTGCGAATATTTTCCAACCAGGAAAAGGCGTAAATAT
GGAGCAGTTAACAAAGACAGACATTTCGAAATATACACATACGACAGAGCAAGTACAAAGTCATTCATTTGCAGATACAT
TTGTAAATATTGTTCCAACGAACATTATGAAGTCATTAGCTGACGGAGATATGCTTGCTATTATCTTCTTCTCAGTATTA
TTTGGTTTAGGTGTAGCAGCAATTGGTGAAAGAGGAAGACCGGTTCTTCAATTTTCCAAGGTGTAG

Upstream 100 bases:

>100_bases
GTAGTGAATTGTCGAATAATATGTAATACTCTTAATTTCAAGTTTTATAGAAATAGAATGAAAGGTAGAGTGACACATCG
AAGAGGGGGTTACAACAAGT

Downstream 100 bases:

>100_bases
CTGATGCAATGTTTTACGTAACGAACCAAGTTATGAAATTTGCACCATTTGGTGTGTTCGCATTGATTGGTGTTACAGTA
TCTACATTCGGTTTAGCTTC

Product: proton/glutamate symporter protein, N-terminus

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKRIGLAWQILIGLALGIAVGAIFFDNPAVVKYLQPIGDIFIRLIKMIVVPIVVASIVVGVAGVGDVKKLGRLGGKTIIY
FEIITTIAIIVGLLIANIFQPGKGVNMEQLTKTDISKYTHTTEQVQSHSFADTFVNIVPTNIMKSLADGDMLAIIFFSVL
FGLGVAAIGERGRPVLQFSKV

Sequences:

>Translated_181_residues
MKRIGLAWQILIGLALGIAVGAIFFDNPAVVKYLQPIGDIFIRLIKMIVVPIVVASIVVGVAGVGDVKKLGRLGGKTIIY
FEIITTIAIIVGLLIANIFQPGKGVNMEQLTKTDISKYTHTTEQVQSHSFADTFVNIVPTNIMKSLADGDMLAIIFFSVL
FGLGVAAIGERGRPVLQFSKV
>Mature_181_residues
MKRIGLAWQILIGLALGIAVGAIFFDNPAVVKYLQPIGDIFIRLIKMIVVPIVVASIVVGVAGVGDVKKLGRLGGKTIIY
FEIITTIAIIVGLLIANIFQPGKGVNMEQLTKTDISKYTHTTEQVQSHSFADTFVNIVPTNIMKSLADGDMLAIIFFSVL
FGLGVAAIGERGRPVLQFSKV

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=115, Percent_Identity=29.5652173913043, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI194239697, Length=125, Percent_Identity=29.6, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1790514, Length=181, Percent_Identity=56.9060773480663, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1789947, Length=180, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17537407, Length=193, Percent_Identity=29.0155440414508, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71996953, Length=215, Percent_Identity=24.1860465116279, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 19454; Mature: 19454

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIGLAWQILIGLALGIAVGAIFFDNPAVVKYLQPIGDIFIRLIKMIVVPIVVASIVVG
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGVGDVKKLGRLGGKTIIYFEIITTIAIIVGLLIANIFQPGKGVNMEQLTKTDISKYTH
HCCCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TTEQVQSHSFADTFVNIVPTNIMKSLADGDMLAIIFFSVLFGLGVAAIGERGRPVLQFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
V
C
>Mature Secondary Structure
MKRIGLAWQILIGLALGIAVGAIFFDNPAVVKYLQPIGDIFIRLIKMIVVPIVVASIVVG
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGVGDVKKLGRLGGKTIIYFEIITTIAIIVGLLIANIFQPGKGVNMEQLTKTDISKYTH
HCCCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TTEQVQSHSFADTFVNIVPTNIMKSLADGDMLAIIFFSVLFGLGVAAIGERGRPVLQFSK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1359385 [H]