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The map label for this gene is spxA

Identifier: 49184129

GI number: 49184129

Start: 1163491

End: 1163886

Strand: Direct

Name: spxA

Synonym: BAS1109

Alternate gene names: 49184129

Gene position: 1163491-1163886 (Clockwise)

Preceding gene: 49184127

Following gene: 49184131

Centisome position: 22.25

GC content: 35.86

Gene sequence:

>396_bases
ATGGTAACATTATATAGTTCTCCAAGCTGTACGTCTTGTAGAAAGGCGAAATTATGGCTAGAGGAAAATCATATTCCTTA
TACAGAACGTAATATTTTCTCAGATCCATTAACGATTGAGGAAATTAAAGAGATTTTACGTATGACAGAAAGCGGAACGG
ATGAGATTATTTCTACTCGTTCAAAAGTTTTCCAAGAATTAAATGTAAACTTAGAGTCTTTACCACTTCAAGATTTATAT
AAGATGATTCGTGACTATCCAGGGATTTTACGTCGTCCAATTATGATTGACGAGAAACGCCTTCAAGTAGGTTACAATGA
AGACGAAATCCGCCGTTTCTTACCACGTACAGTAAGAACGTTCCAATTGCGTGAAGCACAGCGTCTTGTAAATTAA

Upstream 100 bases:

>100_bases
ACTTTGTTTTAAGACAAGGTATCGTGAAAAATTGCTGAATTTAGAAATTTAAACTGTAATTAGTACAGAATTTGTACTCT
TTAAGGAGAGTGAGCTTTGT

Downstream 100 bases:

>100_bases
TTATAATAATATGAAAACCTTCTACCTATTATATAGTAGAAGGTTTTTTTTAATGCTTCACATTGCGTAATCGAACTTGT
TGTACGATAAAGCCGATGCA

Product: transcriptional regulator Spx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MVTLYSSPSCTSCRKAKLWLEENHIPYTERNIFSDPLTIEEIKEILRMTESGTDEIISTRSKVFQELNVNLESLPLQDLY
KMIRDYPGILRRPIMIDEKRLQVGYNEDEIRRFLPRTVRTFQLREAQRLVN

Sequences:

>Translated_131_residues
MVTLYSSPSCTSCRKAKLWLEENHIPYTERNIFSDPLTIEEIKEILRMTESGTDEIISTRSKVFQELNVNLESLPLQDLY
KMIRDYPGILRRPIMIDEKRLQVGYNEDEIRRFLPRTVRTFQLREAQRLVN
>Mature_131_residues
MVTLYSSPSCTSCRKAKLWLEENHIPYTERNIFSDPLTIEEIKEILRMTESGTDEIISTRSKVFQELNVNLESLPLQDLY
KMIRDYPGILRRPIMIDEKRLQVGYNEDEIRRFLPRTVRTFQLREAQRLVN

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPX1_BACAN (Q81TR6)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843675.1
- RefSeq:   YP_017813.1
- RefSeq:   YP_027381.1
- ProteinModelPortal:   Q81TR6
- SMR:   Q81TR6
- EnsemblBacteria:   EBBACT00000011842
- EnsemblBacteria:   EBBACT00000014923
- EnsemblBacteria:   EBBACT00000022336
- GeneID:   1089241
- GeneID:   2816500
- GeneID:   2849962
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_1200
- KEGG:   bar:GBAA_1200
- KEGG:   bat:BAS1109
- TIGR:   BA_1200
- TIGR:   GBAA_1200
- GeneTree:   EBGT00050000001358
- HOGENOM:   HBG734370
- OMA:   RRMQVGY
- ProtClustDB:   PRK01655
- BioCyc:   BANT260799:BAS1109-MONOMER
- BioCyc:   BANT261594:GBAA1200-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01132
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR01617

Pfam domain/function: PF03960 ArsC; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 15593; Mature: 15593

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS51353 ARSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLYSSPSCTSCRKAKLWLEENHIPYTERNIFSDPLTIEEIKEILRMTESGTDEIISTR
CEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
SKVFQELNVNLESLPLQDLYKMIRDYPGILRRPIMIDEKRLQVGYNEDEIRRFLPRTVRT
HHHHHHHCCCHHCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
FQLREAQRLVN
HHHHHHHHHCC
>Mature Secondary Structure
MVTLYSSPSCTSCRKAKLWLEENHIPYTERNIFSDPLTIEEIKEILRMTESGTDEIISTR
CEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
SKVFQELNVNLESLPLQDLYKMIRDYPGILRRPIMIDEKRLQVGYNEDEIRRFLPRTVRT
HHHHHHHCCCHHCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
FQLREAQRLVN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629