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The map label for this gene is rbsK [H]

Identifier: 49183657

GI number: 49183657

Start: 683107

End: 684003

Strand: Direct

Name: rbsK [H]

Synonym: BAS0632

Alternate gene names: 49183657

Gene position: 683107-684003 (Clockwise)

Preceding gene: 49183656

Following gene: 49183658

Centisome position: 13.06

GC content: 41.58

Gene sequence:

>897_bases
ATGCCAAATATTGCAGTAGTAGGTAGTATTTCAATGGACTTAGTGGCCGTTTCAAAAAAACGTCCGAAAGCAGGGGAAAC
AGTAATTGGTGAAGCATTTCATACAATTCCAGGAGGGAAAGGAGCTAACCAGGCGGTTGCTGCAGCTAGATTAGGCGCAA
ATGTAGCGATGGTTGGAGCAGTAGGAGACGATAATTATGGAACTGTAGTGAAGAGAAATTTAGAGAACGAACGCGTTTTT
ATCGACTATGTGGTACCGGTTACAGATGCGGCGACAGGAATTGCTCATATCGTTTTAGCAGAAGAGGATAACAGTATTGT
TGTCGTGCAAGGGGCGAATGCTCTTGTAAATGAGTCGGTTGTAAATCGTTCAAAAGATCTTCTTATAAAAGCTGATATGG
TTGTGCTTCAACTAGAGATTCCGCTTGAAACAGTAAAATATGTATTGGCTATTTGTCAGGAACACAAAATCCCGGTTATG
TTAAATCCAGCGCCAGCACAAGTGTTATCAGAAGATATTTTAGAAAAGGCAACTTATATTACACCAAATGAACATGAGTG
CCGCATCGTATTAGATGATTTCACATCGCCAATTGAAGATTTACTGGCTAAATATCCGAATAAACTATTGATGACAGAAG
GTTCTAACGGTGTACGTTTCCATAATGGTACGGAGATTGTACATGTTCCTAGCATTGCTGTTGATGTAGTAGATACGACT
GGAGCTGGTGATACATTTAATGGTGCATTAGCAGTTGCGCTTTCTGAAGGAGAAACACTTCAAAAAGCAATTCGTTTTGC
GAATATTGCTGGTGGTCTTTCTGTAACGAAGCTTGGGGCGCAAGGCGGTATGCCAACGAGAGATAGAGTACGTGAAGTGC
AGGTGATTGTCGGGTGA

Upstream 100 bases:

>100_bases
TTGTTAGAGCAGATGGAAGGAAACGTATTAGAAGAGAAACACTATCGTTTACCGATTGAAATTATAGAACGAAATACAAC
GAAGTAAGGAGATGAAATAG

Downstream 100 bases:

>100_bases
AAAAGCACGGCGTATTAAACAGTGAGATTGCAGCAGTGCTTGCTTCACTTGGGCATACGGATACGATTGTAATCGCTGAT
TGCGGTTTACCAATTCCTGA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVKRNLENERVF
IDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVNRSKDLLIKADMVVLQLEIPLETVKYVLAICQEHKIPVM
LNPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG

Sequences:

>Translated_298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVKRNLENERVF
IDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVNRSKDLLIKADMVVLQLEIPLETVKYVLAICQEHKIPVM
LNPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG
>Mature_297_residues
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVKRNLENERVFI
DYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVNRSKDLLIKADMVVLQLEIPLETVKYVLAICQEHKIPVML
NPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTTG
AGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=34.4709897610922, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1790193, Length=296, Percent_Identity=38.5135135135135, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=29.8701298701299, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789432, Length=291, Percent_Identity=28.5223367697594, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081971, Length=270, Percent_Identity=25.5555555555556, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788491, Length=288, Percent_Identity=23.9583333333333, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=35.3333333333333, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25147470, Length=306, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=33.134328358209, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=27.9605263157895, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31521; Mature: 31389

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGA
CCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNYGTVVKRNLENERVFIDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESV
CCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VNRSKDLLIKADMVVLQLEIPLETVKYVLAICQEHKIPVMLNPAPAQVLSEDILEKATYI
HCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCC
TPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCEEEECCCEEEEECCEEEEEEECC
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEEEEEC
>Mature Secondary Structure 
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGA
CCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNYGTVVKRNLENERVFIDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESV
CCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VNRSKDLLIKADMVVLQLEIPLETVKYVLAICQEHKIPVMLNPAPAQVLSEDILEKATYI
HCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCC
TPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCEEEECCCEEEEECCEEEEEEECC
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]