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The map label for this gene is 46447606

Identifier: 46447606

GI number: 46447606

Start: 2351635

End: 2353578

Strand: Direct

Name: 46447606

Synonym: pc1972

Alternate gene names: NA

Gene position: 2351635-2353578 (Clockwise)

Preceding gene: 46447604

Following gene: 46447607

Centisome position: 97.4

GC content: 37.14

Gene sequence:

>1944_bases
TTGAGTATAAAAGATTTAAGTTTCGCGAAGCAAGTTTGCAGGGAATGGAAGCAGCTCATTTCAGAAAAAAATGTATGGAA
AACAAAATTAAAACAGTTCTTTTTAGAAAAAAAGTTAGCGAAAATTTGCATAGAACATTTGGATGAACAGCAGTCGATAG
AAAATTTATCTGATGAGATTCATCTTTATATTTTTTCCTTCTTATCTTTTCAAGACTTAGCCACTGTCCGTAGAGTGAGC
AAACAGTGGTATTCAAAAACCTCCGATGACTTAATTTGGAAGATTTTTCTCGAGAAAATTTTTCCTCTTTTTTCTTATGC
ATCAAAGAAAATGGGAATTCATCCTAAAGATCAATTAATGGCTCAAGCCAATATAAAAACAAACCGGGTGCAAAAAATTA
TCGATTTAACAGCTGCTGCGTTGGAAAAAGGGCATGAATGGAACCCCTACGCATACTTTTCTCCAAATGGTCGGAGAGTG
GTTGTTACTAGTAATGAAAGTATTAGTCTTTGGGATACCCAAACAGGAAAATTTCTAAAAAATTGGGGAAAAGGATGGGA
AGACCGTCCAAATATATCCTTTTCCCCTAATGGGGAGCGGATAATTAGCTCTCCTTGGCAAGTAATGAACTCTCTTTGGC
AAGAAGGAAGTTGTGATCTTTGGAATGCTCAAACAGGAGAATTTTTACAGACTTTGGAAGAAAAGTGTTGTAACGTATAT
TTTTCTCCAAATAGCGAACAATTGGCTACTATTAGCCTTACATCGATTCGCCTTTGGGATGCTCAAACAGGAAAATGCTT
ACAGTTTTTGGGATACAACCCATCTCTTAATGAATCTATATCTTTTTCTTCGGATAGCCAGCGAATAATTAGCAATGACG
GCACATCTGTTTGCCTTTGGGATGCCCAAACAGGAAAATGTTTACAGTCTTTGGAAAATATTACATTGCTTACAACATCC
TTTTCTCCGAACAGTCAGCAGCTGGCTATTTGTGACACGTTATCCATTCGTCTTTTTGATGCCAGAACAGGAAAATTTTT
ACAGACTTTAGAAAATGGCTGCCTTCTCAATTCAAACGTATCTTTTTCTTCAAATAGTCAACGGTTCATTACTAATAATG
GCAAATTCGTTCGTCTTTGGGATGCCCAAACGAGAAAATGTTTAAAAACTCTTAAAGAAGGTCCAGAGTACACGACAACC
TTCTTTTCTCCGAATAGCCAGCGAATAATTACTAGTACCTGCAGATCTATTTGCCTTTGGGATACTCAAGCAGGCGAATA
TCTGGAGACGTTGGAAAAAAACAAATGGGGCATAAAAGTGAATTTTTCTCCAAATAGCCAGCGAATAGTTACTGCTAGCT
GCCAATTTTTTCGTCTTTTTGATGCCCAAACAGGAAAATGCTTACAGCAGACGCTGGAAAAAGGCCAATTTAGCGTAAAA
GCGGTCTTTTCTCCTGATAGCCAGCGCTTAATTACTTATCACGGCCAATCGATTTGCCTTTGGGATGCCCAAACAGGGGT
TTGCTTAAAAACTTGGGAAGAAGAAGAAGCGCATCAAATAGATTTTTTTCCAAATAGCAAATGGATAATTACCGATAACG
GCAAATTCGTTCGCCTTTGGGATGCTACAACAGGAAAATGCTTACACGTCTTGGAAAATCGTCTAGAATCTCAAGGAGTA
ACTTTTTCCTCTAATAAAAAGATATCAATTTCTCCCAACGGAGGGCAACTATTGATAGATATGAAAATTTTCGATTATTT
CCCTTCTAAAAAAGAAGATTTTGAGTCTGAGGAAAACACCTCTTTAACACAAGAATCGACAGGACGAGAATCAAAAAAGA
GAAAAGTCAGAAGTGTTAAAGGTAAAGAAGATAGCAGCAAGTTCTCGTGCGAATTACAGCGTAATCCGGCTTTTTCAAAG
AAAAAAAGAAAAAAAGAGGATTAA

Upstream 100 bases:

>100_bases
TTATCCTCATATATTTCCAGCATTTAAAGAATTAGAAAAAAAGCAAATATTTTCTAATACAAATGTATATGTAGAAATTG
GAGTAAAAATATTCTCAAAG

Downstream 100 bases:

>100_bases
TAAAAAATTCATTTAAATTTTAAAAGTCTTTTTAAAGAGGGACGAGTTAAAAGCTAGTTTTTAACGCCAATAACTAGTTG
CCGCGTTAAGTTAGCCATGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 646

Protein sequence:

>647_residues
MSIKDLSFAKQVCREWKQLISEKNVWKTKLKQFFLEKKLAKICIEHLDEQQSIENLSDEIHLYIFSFLSFQDLATVRRVS
KQWYSKTSDDLIWKIFLEKIFPLFSYASKKMGIHPKDQLMAQANIKTNRVQKIIDLTAAALEKGHEWNPYAYFSPNGRRV
VVTSNESISLWDTQTGKFLKNWGKGWEDRPNISFSPNGERIISSPWQVMNSLWQEGSCDLWNAQTGEFLQTLEEKCCNVY
FSPNSEQLATISLTSIRLWDAQTGKCLQFLGYNPSLNESISFSSDSQRIISNDGTSVCLWDAQTGKCLQSLENITLLTTS
FSPNSQQLAICDTLSIRLFDARTGKFLQTLENGCLLNSNVSFSSNSQRFITNNGKFVRLWDAQTRKCLKTLKEGPEYTTT
FFSPNSQRIITSTCRSICLWDTQAGEYLETLEKNKWGIKVNFSPNSQRIVTASCQFFRLFDAQTGKCLQQTLEKGQFSVK
AVFSPDSQRLITYHGQSICLWDAQTGVCLKTWEEEEAHQIDFFPNSKWIITDNGKFVRLWDATTGKCLHVLENRLESQGV
TFSSNKKISISPNGGQLLIDMKIFDYFPSKKEDFESEENTSLTQESTGRESKKRKVRSVKGKEDSSKFSCELQRNPAFSK
KKRKKED

Sequences:

>Translated_647_residues
MSIKDLSFAKQVCREWKQLISEKNVWKTKLKQFFLEKKLAKICIEHLDEQQSIENLSDEIHLYIFSFLSFQDLATVRRVS
KQWYSKTSDDLIWKIFLEKIFPLFSYASKKMGIHPKDQLMAQANIKTNRVQKIIDLTAAALEKGHEWNPYAYFSPNGRRV
VVTSNESISLWDTQTGKFLKNWGKGWEDRPNISFSPNGERIISSPWQVMNSLWQEGSCDLWNAQTGEFLQTLEEKCCNVY
FSPNSEQLATISLTSIRLWDAQTGKCLQFLGYNPSLNESISFSSDSQRIISNDGTSVCLWDAQTGKCLQSLENITLLTTS
FSPNSQQLAICDTLSIRLFDARTGKFLQTLENGCLLNSNVSFSSNSQRFITNNGKFVRLWDAQTRKCLKTLKEGPEYTTT
FFSPNSQRIITSTCRSICLWDTQAGEYLETLEKNKWGIKVNFSPNSQRIVTASCQFFRLFDAQTGKCLQQTLEKGQFSVK
AVFSPDSQRLITYHGQSICLWDAQTGVCLKTWEEEEAHQIDFFPNSKWIITDNGKFVRLWDATTGKCLHVLENRLESQGV
TFSSNKKISISPNGGQLLIDMKIFDYFPSKKEDFESEENTSLTQESTGRESKKRKVRSVKGKEDSSKFSCELQRNPAFSK
KKRKKED
>Mature_646_residues
SIKDLSFAKQVCREWKQLISEKNVWKTKLKQFFLEKKLAKICIEHLDEQQSIENLSDEIHLYIFSFLSFQDLATVRRVSK
QWYSKTSDDLIWKIFLEKIFPLFSYASKKMGIHPKDQLMAQANIKTNRVQKIIDLTAAALEKGHEWNPYAYFSPNGRRVV
VTSNESISLWDTQTGKFLKNWGKGWEDRPNISFSPNGERIISSPWQVMNSLWQEGSCDLWNAQTGEFLQTLEEKCCNVYF
SPNSEQLATISLTSIRLWDAQTGKCLQFLGYNPSLNESISFSSDSQRIISNDGTSVCLWDAQTGKCLQSLENITLLTTSF
SPNSQQLAICDTLSIRLFDARTGKFLQTLENGCLLNSNVSFSSNSQRFITNNGKFVRLWDAQTRKCLKTLKEGPEYTTTF
FSPNSQRIITSTCRSICLWDTQAGEYLETLEKNKWGIKVNFSPNSQRIVTASCQFFRLFDAQTGKCLQQTLEKGQFSVKA
VFSPDSQRLITYHGQSICLWDAQTGVCLKTWEEEEAHQIDFFPNSKWIITDNGKFVRLWDATTGKCLHVLENRLESQGVT
FSSNKKISISPNGGQLLIDMKIFDYFPSKKEDFESEENTSLTQESTGRESKKRKVRSVKGKEDSSKFSCELQRNPAFSKK
KRKKED

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 15 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI61743926, Length=405, Percent_Identity=27.1604938271605, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI16117781, Length=405, Percent_Identity=27.1604938271605, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI16117779, Length=405, Percent_Identity=27.1604938271605, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI23199987, Length=268, Percent_Identity=30.5970149253731, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI16554629, Length=251, Percent_Identity=29.4820717131474, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI16554627, Length=251, Percent_Identity=29.4820717131474, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI32189425, Length=288, Percent_Identity=27.0833333333333, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI113865883, Length=292, Percent_Identity=25.3424657534247, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI13376840, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568701, Length=354, Percent_Identity=24.2937853107345, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17552164, Length=246, Percent_Identity=28.4552845528455, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17864654, Length=252, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356075, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24654584, Length=199, Percent_Identity=30.6532663316583, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24657400, Length=421, Percent_Identity=23.7529691211401, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24657405, Length=421, Percent_Identity=23.7529691211401, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17737533, Length=421, Percent_Identity=23.7529691211401, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000767
- InterPro:   IPR020472
- InterPro:   IPR002182
- InterPro:   IPR015943
- InterPro:   IPR001680
- InterPro:   IPR011046
- InterPro:   IPR019782
- InterPro:   IPR019775
- InterPro:   IPR017986
- InterPro:   IPR019781 [H]

Pfam domain/function: PF00931 NB-ARC; PF00400 WD40 [H]

EC number: NA

Molecular weight: Translated: 74318; Mature: 74187

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50181 FBOX ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKDLSFAKQVCREWKQLISEKNVWKTKLKQFFLEKKLAKICIEHLDEQQSIENLSDEI
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HLYIFSFLSFQDLATVRRVSKQWYSKTSDDLIWKIFLEKIFPLFSYASKKMGIHPKDQLM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AQANIKTNRVQKIIDLTAAALEKGHEWNPYAYFSPNGRRVVVTSNESISLWDTQTGKFLK
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCEEEEEECCCHHHHH
NWGKGWEDRPNISFSPNGERIISSPWQVMNSLWQEGSCDLWNAQTGEFLQTLEEKCCNVY
HHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEEE
FSPNSEQLATISLTSIRLWDAQTGKCLQFLGYNPSLNESISFSSDSQRIISNDGTSVCLW
ECCCCCCEEEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCEEEEE
DAQTGKCLQSLENITLLTTSFSPNSQQLAICDTLSIRLFDARTGKFLQTLENGCLLNSNV
ECCHHHHHHHHCCEEEEEEECCCCCCEEEEEEEEEEEEEECCCHHHHHHHHCCEEEECCC
SFSSNSQRFITNNGKFVRLWDAQTRKCLKTLKEGPEYTTTFFSPNSQRIITSTCRSICLW
CCCCCCCEEEECCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHEEEE
DTQAGEYLETLEKNKWGIKVNFSPNSQRIVTASCQFFRLFDAQTGKCLQQTLEKGQFSVK
CCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECEEEEEEECCCCCHHHHHHHHCCCEEEE
AVFSPDSQRLITYHGQSICLWDAQTGVCLKTWEEEEAHQIDFFPNSKWIITDNGKFVRLW
EEECCCCCEEEEECCCEEEEEECCCCCEEECCCCCCCCEEEECCCCEEEEECCCCEEEEE
DATTGKCLHVLENRLESQGVTFSSNKKISISPNGGQLLIDMKIFDYFPSKKEDFESEENT
CCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCC
SLTQESTGRESKKRKVRSVKGKEDSSKFSCELQRNPAFSKKKRKKED
CCCHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCC
>Mature Secondary Structure 
SIKDLSFAKQVCREWKQLISEKNVWKTKLKQFFLEKKLAKICIEHLDEQQSIENLSDEI
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HLYIFSFLSFQDLATVRRVSKQWYSKTSDDLIWKIFLEKIFPLFSYASKKMGIHPKDQLM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AQANIKTNRVQKIIDLTAAALEKGHEWNPYAYFSPNGRRVVVTSNESISLWDTQTGKFLK
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCEEEEEECCCHHHHH
NWGKGWEDRPNISFSPNGERIISSPWQVMNSLWQEGSCDLWNAQTGEFLQTLEEKCCNVY
HHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEEE
FSPNSEQLATISLTSIRLWDAQTGKCLQFLGYNPSLNESISFSSDSQRIISNDGTSVCLW
ECCCCCCEEEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCEEEEE
DAQTGKCLQSLENITLLTTSFSPNSQQLAICDTLSIRLFDARTGKFLQTLENGCLLNSNV
ECCHHHHHHHHCCEEEEEEECCCCCCEEEEEEEEEEEEEECCCHHHHHHHHCCEEEECCC
SFSSNSQRFITNNGKFVRLWDAQTRKCLKTLKEGPEYTTTFFSPNSQRIITSTCRSICLW
CCCCCCCEEEECCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHEEEE
DTQAGEYLETLEKNKWGIKVNFSPNSQRIVTASCQFFRLFDAQTGKCLQQTLEKGQFSVK
CCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECEEEEEEECCCCCHHHHHHHHCCCEEEE
AVFSPDSQRLITYHGQSICLWDAQTGVCLKTWEEEEAHQIDFFPNSKWIITDNGKFVRLW
EEECCCCCEEEEECCCEEEEEECCCCCEEECCCCCCCCEEEECCCCEEEEECCCCEEEEE
DATTGKCLHVLENRLESQGVTFSSNKKISISPNGGQLLIDMKIFDYFPSKKEDFESEENT
CCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCC
SLTQESTGRESKKRKVRSVKGKEDSSKFSCELQRNPAFSKKKRKKED
CCCHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]