Click here to switch to the map view.

The map label for this gene is yqhT [H]

Identifier: 46447514

GI number: 46447514

Start: 2240785

End: 2241783

Strand: Direct

Name: yqhT [H]

Synonym: pc1880

Alternate gene names: 46447514

Gene position: 2240785-2241783 (Clockwise)

Preceding gene: 46447506

Following gene: 46447515

Centisome position: 92.81

GC content: 36.34

Gene sequence:

>999_bases
TTGCCTTGCGATGTACTCTTAATTGAACATCCCACCCACATTCTCTATTTAACAGGATTGGAATTATCTGCCGGGAAAAT
TCTAGTTAGCGAAAATCAAACATGTTTGATTGTGGATGGACGATATTTTGAAATTTGCAACCAACAAACTCTTTATCCTG
TCATTCTTCTTCACGAATCTTCTCTCACAAATTGGTTAAAAGAATACCAATTAAAAAATTTGGGGATAGATCCAGAGACA
ACAACTTTTGGAAGATACTCTTTTTTATCTAGCTCTCTTTCTTCATGCACTATCATCCCTATTCCTTCTCCCTTACAAGA
AATGCGTCTGATTAAAGATGAACAAGAGATTATTTATTTAAAAGAATCGGCAAAACTAGCTTTAGAAGGATATCATTATT
TAAAAACTTTACTCCAAGTAGGAGTAACAGAGGCAGAATTAGCCTTTGAATTGGAATTTTTCTGGAAAAAAAAGGGGGCG
AAACAATTAGCCTTTGATCCAATTATTGCTTTTGGCTTTAATAGCTCAAAGCCTCATTATCGAGCTGATAAAGAAATTTT
ACAGGCTAACATGCCTGTGTTAATTGATATTGGAGTTGTCGTTCATCATTATCACTCGGATATGACTCGAGTTGATTTTT
TTGGGAATGTTTCTGAACAAATTCAGTCTATTTATTCTATTGTTGAGGAAGCAAAGCATCAAGCAATGCATTTATGCAAA
CCAGGCACTTTGATAGGAGAACTCGACAATACTGCGCGCTCTTTCATTGAATCCAAAGGATATGGCGATTATTTTACCCA
CAGTCTTGGACATGGAATTGGTTTAGATATCCACGAATCTCCTACCATTCGACGCTCAGGTCCATTTAGTGATTATCCTT
TACAAGCAGGAATGGTCATCACGATTGAACCGGGAATTTATCTTAAAGGAGTTGGAGGCGTACGATTAGAAGATACTCTT
TTGATTACAGAAACGGGTTATGAGATTCTGACTCAATAG

Upstream 100 bases:

>100_bases
GTGTTCCTTTATTCAATATCACATAAAAAATAATTGAATCTTACTTATTCTTATGAACTACGTCAATCGATTATGCAAAC
TTAGAGAAAAACTATCTTCT

Downstream 100 bases:

>100_bases
TCATTACAAAATATATTCATTATCTATAAAAAAATTAGGAAATAATTGATTATTTCATTAAGTTAACCCAATCTTAACTA
ACTAACAGCAAATTATTTAC

Product: putative X-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPCDVLLIEHPTHILYLTGLELSAGKILVSENQTCLIVDGRYFEICNQQTLYPVILLHESSLTNWLKEYQLKNLGIDPET
TTFGRYSFLSSSLSSCTIIPIPSPLQEMRLIKDEQEIIYLKESAKLALEGYHYLKTLLQVGVTEAELAFELEFFWKKKGA
KQLAFDPIIAFGFNSSKPHYRADKEILQANMPVLIDIGVVVHHYHSDMTRVDFFGNVSEQIQSIYSIVEEAKHQAMHLCK
PGTLIGELDNTARSFIESKGYGDYFTHSLGHGIGLDIHESPTIRRSGPFSDYPLQAGMVITIEPGIYLKGVGGVRLEDTL
LITETGYEILTQ

Sequences:

>Translated_332_residues
MPCDVLLIEHPTHILYLTGLELSAGKILVSENQTCLIVDGRYFEICNQQTLYPVILLHESSLTNWLKEYQLKNLGIDPET
TTFGRYSFLSSSLSSCTIIPIPSPLQEMRLIKDEQEIIYLKESAKLALEGYHYLKTLLQVGVTEAELAFELEFFWKKKGA
KQLAFDPIIAFGFNSSKPHYRADKEILQANMPVLIDIGVVVHHYHSDMTRVDFFGNVSEQIQSIYSIVEEAKHQAMHLCK
PGTLIGELDNTARSFIESKGYGDYFTHSLGHGIGLDIHESPTIRRSGPFSDYPLQAGMVITIEPGIYLKGVGGVRLEDTL
LITETGYEILTQ
>Mature_331_residues
PCDVLLIEHPTHILYLTGLELSAGKILVSENQTCLIVDGRYFEICNQQTLYPVILLHESSLTNWLKEYQLKNLGIDPETT
TFGRYSFLSSSLSSCTIIPIPSPLQEMRLIKDEQEIIYLKESAKLALEGYHYLKTLLQVGVTEAELAFELEFFWKKKGAK
QLAFDPIIAFGFNSSKPHYRADKEILQANMPVLIDIGVVVHHYHSDMTRVDFFGNVSEQIQSIYSIVEEAKHQAMHLCKP
GTLIGELDNTARSFIESKGYGDYFTHSLGHGIGLDIHESPTIRRSGPFSDYPLQAGMVITIEPGIYLKGVGGVRLEDTLL
ITETGYEILTQ

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=256, Percent_Identity=31.25, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI260593665, Length=286, Percent_Identity=24.1258741258741, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI149589008, Length=286, Percent_Identity=24.1258741258741, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI264681563, Length=212, Percent_Identity=32.5471698113208, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI40385867, Length=244, Percent_Identity=25.8196721311475, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI264681565, Length=209, Percent_Identity=31.1004784688995, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788728, Length=323, Percent_Identity=33.4365325077399, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789275, Length=267, Percent_Identity=28.0898876404494, Blast_Score=98, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17508215, Length=298, Percent_Identity=25.8389261744966, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=26.1484098939929, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320922, Length=265, Percent_Identity=25.6603773584906, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322999, Length=244, Percent_Identity=28.6885245901639, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19920384, Length=270, Percent_Identity=27.037037037037, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=25.3061224489796, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357079, Length=298, Percent_Identity=25.503355704698, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 37361; Mature: 37230

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCDVLLIEHPTHILYLTGLELSAGKILVSENQTCLIVDGRYFEICNQQTLYPVILLHES
CCCEEEEEECCCEEEEEECCEECCCEEEEECCCEEEEECCCEEEECCCCCEEEEEEEECC
SLTNWLKEYQLKNLGIDPETTTFGRYSFLSSSLSSCTIIPIPSPLQEMRLIKDEQEIIYL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCEEEEE
KESAKLALEGYHYLKTLLQVGVTEAELAFELEFFWKKKGAKQLAFDPIIAFGFNSSKPHY
ECCCEEEEHHHHHHHHHHHCCCCCHHHEEEEEEEEHHCCCCCEECCCEEEECCCCCCCCC
RADKEILQANMPVLIDIGVVVHHYHSDMTRVDFFGNVSEQIQSIYSIVEEAKHQAMHLCK
HHHHHHHHCCCCEEEEEEEHEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
PGTLIGELDNTARSFIESKGYGDYFTHSLGHGIGLDIHESPTIRRSGPFSDYPLQAGMVI
CCCEEEHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCEEE
TIEPGIYLKGVGGVRLEDTLLITETGYEILTQ
EECCCEEEECCCCCEEEEEEEEEECCHHHHCC
>Mature Secondary Structure 
PCDVLLIEHPTHILYLTGLELSAGKILVSENQTCLIVDGRYFEICNQQTLYPVILLHES
CCEEEEEECCCEEEEEECCEECCCEEEEECCCEEEEECCCEEEECCCCCEEEEEEEECC
SLTNWLKEYQLKNLGIDPETTTFGRYSFLSSSLSSCTIIPIPSPLQEMRLIKDEQEIIYL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCEEEEE
KESAKLALEGYHYLKTLLQVGVTEAELAFELEFFWKKKGAKQLAFDPIIAFGFNSSKPHY
ECCCEEEEHHHHHHHHHHHCCCCCHHHEEEEEEEEHHCCCCCEECCCEEEECCCCCCCCC
RADKEILQANMPVLIDIGVVVHHYHSDMTRVDFFGNVSEQIQSIYSIVEEAKHQAMHLCK
HHHHHHHHCCCCEEEEEEEHEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
PGTLIGELDNTARSFIESKGYGDYFTHSLGHGIGLDIHESPTIRRSGPFSDYPLQAGMVI
CCCEEEHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCEEE
TIEPGIYLKGVGGVRLEDTLLITETGYEILTQ
EECCCEEEECCCCCEEEEEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]