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The map label for this gene is apeB [H]

Identifier: 46447124

GI number: 46447124

Start: 1773972

End: 1775276

Strand: Direct

Name: apeB [H]

Synonym: pc1490

Alternate gene names: 46447124

Gene position: 1773972-1775276 (Clockwise)

Preceding gene: 46447123

Following gene: 46447126

Centisome position: 73.47

GC content: 35.86

Gene sequence:

>1305_bases
ATGAAAAATTACTATTTAAATGACTTACTCTCATATTTAAACAACGCTCCTACACCTTGGCATGCAGTCGAAGAAGCTTG
TCAAAGACTTTCCAAACATGGATACACTGAGTTAAAAGAAAATGAGAAATGGGAACTAAAACTCGGACACAGTTATTATA
TTAAACATCATCAAACTACGCTTTGCGTTTTTACTCTTCCTAAAAATTCACCTACACGCGTTCGTTTATTGGCTTCTCAT
ACAGACAGTCCAGGATTTAAACTTAAACCCCAAGCAGAAATCCGCCGTCATTCAATGATTTTATTGGGTGTTGAAATCTA
TGGATCCCCTCTTTTAAACTCTTGGTTAAATCGAGACCTTGGAATCGCTGGACACATTATTTATAAAAATAAAAATAATC
AGCCAGAAAATTGTTTAGTACAATTAGACAGTTTTCCCGTTGTCATTCCACAATTAGCTATTCATCTAGATCGAGAAGTA
AACGAAAAAGGACTTTTATTAAATAAACAAGAACATTTAAATGCATTAGCCGCATTAGAAAAAGATATTCCAACAGGGCA
GACTTATTTAGAAACTATTTTAAAAAAACAGATTGATTTTCAGGAACTTTTAACATTCGATTTATTTCTTTATCCCCTTG
ATAAAGCTCGATTTGTTGGCTTCGAAAATCAGTTCATCTCTTCTTATCGAATCGATAGCTTAGCTAGTGTCCATGCTGCC
CTTTCAGCACTTATTGAAACAGCAACTCCTCTTGAAAATGATATAAAGATGGCCATTTTTTGGAATCATGAAGAAGTCGG
CTCACACACATCTCAAGGAGCAGAATCTCCCTTTTTTCATCAAACATTAGAAAGAATTTTATTAAATCTAAATTGTTCAA
AAGAAGATTTTTTTCGCTTACTTAACCAATCACATTGCACTTCGATTGATTTAGCTCACGCTTTGCATCCAAACTATCTA
GATAAACACGATGGGATGCACCAACCTAAACTAGGGCAGGGAGTTATCATCAAAAATAACGCTCAACAGCGATATGCTTC
AACTGCAACTTCATCCATTCCCATTCATCTTGCCGCAGGAATAGAGCAAATTCCTCTCCAGCATTTTGTCAGTCGTAACG
ATATGCCCTGTGGCTCAACTATTGGACCTTTGCAAGCATGTACGGCGGGAATTTCAACGGTAGATATTGGTTGTGGCGAA
CTTTCTATGCATTCTTGCCGAGAGTTAATGGCCTCAGAAGATTATATTCATCTACTCAATCTATTAAAAGTAATTTTAAA
AATGCCGGATTGGCCAATTATTTAA

Upstream 100 bases:

>100_bases
AAATCATATTCACAAATACCTAAGGTAACTTAAAACTTACCTTAGGTATTTTTTTGTCTATGTAAATCCTATTAACTTTT
GGAAGTCCGGAGTCTAAAGT

Downstream 100 bases:

>100_bases
TCAAAATAAAAATCGCCTTTTCAATGTGAGTTGAAAAGGCGATAAAAATTTAAAAAGATTAAACTGCTTGAAGGTTGGGA
TCTTTAGTAGGATCTTTAGG

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKNYYLNDLLSYLNNAPTPWHAVEEACQRLSKHGYTELKENEKWELKLGHSYYIKHHQTTLCVFTLPKNSPTRVRLLASH
TDSPGFKLKPQAEIRRHSMILLGVEIYGSPLLNSWLNRDLGIAGHIIYKNKNNQPENCLVQLDSFPVVIPQLAIHLDREV
NEKGLLLNKQEHLNALAALEKDIPTGQTYLETILKKQIDFQELLTFDLFLYPLDKARFVGFENQFISSYRIDSLASVHAA
LSALIETATPLENDIKMAIFWNHEEVGSHTSQGAESPFFHQTLERILLNLNCSKEDFFRLLNQSHCTSIDLAHALHPNYL
DKHDGMHQPKLGQGVIIKNNAQQRYASTATSSIPIHLAAGIEQIPLQHFVSRNDMPCGSTIGPLQACTAGISTVDIGCGE
LSMHSCRELMASEDYIHLLNLLKVILKMPDWPII

Sequences:

>Translated_434_residues
MKNYYLNDLLSYLNNAPTPWHAVEEACQRLSKHGYTELKENEKWELKLGHSYYIKHHQTTLCVFTLPKNSPTRVRLLASH
TDSPGFKLKPQAEIRRHSMILLGVEIYGSPLLNSWLNRDLGIAGHIIYKNKNNQPENCLVQLDSFPVVIPQLAIHLDREV
NEKGLLLNKQEHLNALAALEKDIPTGQTYLETILKKQIDFQELLTFDLFLYPLDKARFVGFENQFISSYRIDSLASVHAA
LSALIETATPLENDIKMAIFWNHEEVGSHTSQGAESPFFHQTLERILLNLNCSKEDFFRLLNQSHCTSIDLAHALHPNYL
DKHDGMHQPKLGQGVIIKNNAQQRYASTATSSIPIHLAAGIEQIPLQHFVSRNDMPCGSTIGPLQACTAGISTVDIGCGE
LSMHSCRELMASEDYIHLLNLLKVILKMPDWPII
>Mature_434_residues
MKNYYLNDLLSYLNNAPTPWHAVEEACQRLSKHGYTELKENEKWELKLGHSYYIKHHQTTLCVFTLPKNSPTRVRLLASH
TDSPGFKLKPQAEIRRHSMILLGVEIYGSPLLNSWLNRDLGIAGHIIYKNKNNQPENCLVQLDSFPVVIPQLAIHLDREV
NEKGLLLNKQEHLNALAALEKDIPTGQTYLETILKKQIDFQELLTFDLFLYPLDKARFVGFENQFISSYRIDSLASVHAA
LSALIETATPLENDIKMAIFWNHEEVGSHTSQGAESPFFHQTLERILLNLNCSKEDFFRLLNQSHCTSIDLAHALHPNYL
DKHDGMHQPKLGQGVIIKNNAQQRYASTATSSIPIHLAAGIEQIPLQHFVSRNDMPCGSTIGPLQACTAGISTVDIGCGE
LSMHSCRELMASEDYIHLLNLLKVILKMPDWPII

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=451, Percent_Identity=34.589800443459, Blast_Score=248, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI17552916, Length=428, Percent_Identity=34.5794392523364, Blast_Score=236, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6321905, Length=465, Percent_Identity=32.9032258064516, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6322746, Length=435, Percent_Identity=27.3563218390805, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 49125; Mature: 49125

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYYLNDLLSYLNNAPTPWHAVEEACQRLSKHGYTELKENEKWELKLGHSYYIKHHQTT
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCEE
LCVFTLPKNSPTRVRLLASHTDSPGFKLKPQAEIRRHSMILLGVEIYGSPLLNSWLNRDL
EEEEECCCCCCCEEEEEEECCCCCCCEECCHHHHHHCEEEEEEHHHHCCHHHHHHHCCCC
GIAGHIIYKNKNNQPENCLVQLDSFPVVIPQLAIHLDREVNEKGLLLNKQEHLNALAALE
CCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHH
KDIPTGQTYLETILKKQIDFQELLTFDLFLYPLDKARFVGFENQFISSYRIDSLASVHAA
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHEEECCHHHCCCCHHHHHHHHHHHHHHHHHHH
LSALIETATPLENDIKMAIFWNHEEVGSHTSQGAESPFFHQTLERILLNLNCSKEDFFRL
HHHHHHHCCCCCCCCEEEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LNQSHCTSIDLAHALHPNYLDKHDGMHQPKLGQGVIIKNNAQQRYASTATSSIPIHLAAG
HCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCEEEECC
IEQIPLQHFVSRNDMPCGSTIGPLQACTAGISTVDIGCGELSMHSCRELMASEDYIHLLN
CHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCHHHHHHH
LLKVILKMPDWPII
HHHHHHHCCCCCCC
>Mature Secondary Structure
MKNYYLNDLLSYLNNAPTPWHAVEEACQRLSKHGYTELKENEKWELKLGHSYYIKHHQTT
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCEE
LCVFTLPKNSPTRVRLLASHTDSPGFKLKPQAEIRRHSMILLGVEIYGSPLLNSWLNRDL
EEEEECCCCCCCEEEEEEECCCCCCCEECCHHHHHHCEEEEEEHHHHCCHHHHHHHCCCC
GIAGHIIYKNKNNQPENCLVQLDSFPVVIPQLAIHLDREVNEKGLLLNKQEHLNALAALE
CCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHH
KDIPTGQTYLETILKKQIDFQELLTFDLFLYPLDKARFVGFENQFISSYRIDSLASVHAA
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHEEECCHHHCCCCHHHHHHHHHHHHHHHHHHH
LSALIETATPLENDIKMAIFWNHEEVGSHTSQGAESPFFHQTLERILLNLNCSKEDFFRL
HHHHHHHCCCCCCCCEEEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LNQSHCTSIDLAHALHPNYLDKHDGMHQPKLGQGVIIKNNAQQRYASTATSSIPIHLAAG
HCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCEEEECC
IEQIPLQHFVSRNDMPCGSTIGPLQACTAGISTVDIGCGELSMHSCRELMASEDYIHLLN
CHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCHHHHHHH
LLKVILKMPDWPII
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA