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The map label for this gene is clpX

Identifier: 46447011

GI number: 46447011

Start: 1651041

End: 1652282

Strand: Direct

Name: clpX

Synonym: pc1377

Alternate gene names: 46447011

Gene position: 1651041-1652282 (Clockwise)

Preceding gene: 46447010

Following gene: 46447012

Centisome position: 68.38

GC content: 35.75

Gene sequence:

>1242_bases
ATGAGTAAAAAGTCTTTAACAAAAGAACTTGCTAGCTGCTCTTTCTGTGGCAGAACTGAAGAGGCCGTTGAAAAACTCAT
TTCAGGACCTAATGTATATATTTGTGATAAATGTGTACGATTATGCACAGGAATTTTAGATAAAAAAGCTCCTTCCACTT
ATGAATTTAAAATTCTCAAGCCTAAAGAAATCAAAGAGAAGCTCGACGAGTACATTATCGGTCAAGAAAACGCAAAAAAA
ACTATTTCAGTAGGTGTCTACAACCACTACAAAAGAATCCGGTCTAAAAATAAAGAAGCAGATGGAATTGAATTTAGCAA
ATCTAATGTTTTACTTTTCGGCCCAACAGGATCAGGTAAAACCTTGATCGCAAAGACTTTAGCTTCTATTTTAGATGTTC
CTTTTACCATTGCAGATGCCACGACATTAACAGAAGCAGGCTATGTCGGCGAAGATGTGGAAAACATTATCTTACGCCTC
TTGCAAGCAGCTGATTACGATGTAGCCAAGGCTGAACAAGGAATCATTTATATTGATGAAATTGATAAAATCAATCGAAC
AACCGCAAATGTATCAATTACTCGGGATGTGTCTGGAGAAGGAGTTCAGCAAGCATTACTCAAAATTGTTGAAGGAACAA
TTGCTAATGTCCCTCCTAAAGGAGGTCGTAAGCACCCAAATCAAGAGTATATTAAAGTGAATACAGAAAATATTCTCTTT
ATTGTAGGTGGTGCTTTTGTTAATTTAGAAAAAATTATTGCAAAAAGGTTAGGACGAAATACAATTGGTTTTGATGGAAG
CAATCGAGAAGTTGTTGACCCAACTCAAAAAAGTTTACTACTTTCCAAAGTCGAACCTGAAGACCTTATTCAATTTGGAA
TGATCCCTGAGTTCGTCGGCCGATTTAATAGCATCGCGAATTGTAATGAGTTGCAATTGCCTGATTTAATTAATATTTTA
ACAGAGCCAAAAAATGCTTTTATTAAGCAATTTATAGCTATGTTTGAAGCCGAAGGGGTGAAACTCCAATTTACAGAAGA
TGCACTAGCTGCTATTGCTCAACAAGCAATTGAAGCAGGGACAGGGGCTAGAGCTTTGCGTCTCATTTTAGAAAACTTGA
TGCGCGAATTAATGTATGAAATTCCTTCCGATGAAACAATCAGTGAAATTCTAATTGAAAAAGAAACAGTTACAGAGAAA
AAACCTCCTATTATTAAACGACATGATCAAAAAATAGCTTAA

Upstream 100 bases:

>100_bases
TAAATACACCGCTCCAAATGAAGCTCTTTCTTTTATATGAATACATTAAACGATAAATACAAAGAGTTTAATTTTTAACC
TTTAGATAAAGTAATCACCC

Downstream 100 bases:

>100_bases
CCGTTTTTCCTGGCGCTGGATATAATCCAGCGTTCCTTAAAAAAGTGATCATGACACCCTCTTTTTCAATTAAAAAAATT
CCTTTCTCTTCCATCCCTTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSKKSLTKELASCSFCGRTEEAVEKLISGPNVYICDKCVRLCTGILDKKAPSTYEFKILKPKEIKEKLDEYIIGQENAKK
TISVGVYNHYKRIRSKNKEADGIEFSKSNVLLFGPTGSGKTLIAKTLASILDVPFTIADATTLTEAGYVGEDVENIILRL
LQAADYDVAKAEQGIIYIDEIDKINRTTANVSITRDVSGEGVQQALLKIVEGTIANVPPKGGRKHPNQEYIKVNTENILF
IVGGAFVNLEKIIAKRLGRNTIGFDGSNREVVDPTQKSLLLSKVEPEDLIQFGMIPEFVGRFNSIANCNELQLPDLINIL
TEPKNAFIKQFIAMFEAEGVKLQFTEDALAAIAQQAIEAGTGARALRLILENLMRELMYEIPSDETISEILIEKETVTEK
KPPIIKRHDQKIA

Sequences:

>Translated_413_residues
MSKKSLTKELASCSFCGRTEEAVEKLISGPNVYICDKCVRLCTGILDKKAPSTYEFKILKPKEIKEKLDEYIIGQENAKK
TISVGVYNHYKRIRSKNKEADGIEFSKSNVLLFGPTGSGKTLIAKTLASILDVPFTIADATTLTEAGYVGEDVENIILRL
LQAADYDVAKAEQGIIYIDEIDKINRTTANVSITRDVSGEGVQQALLKIVEGTIANVPPKGGRKHPNQEYIKVNTENILF
IVGGAFVNLEKIIAKRLGRNTIGFDGSNREVVDPTQKSLLLSKVEPEDLIQFGMIPEFVGRFNSIANCNELQLPDLINIL
TEPKNAFIKQFIAMFEAEGVKLQFTEDALAAIAQQAIEAGTGARALRLILENLMRELMYEIPSDETISEILIEKETVTEK
KPPIIKRHDQKIA
>Mature_412_residues
SKKSLTKELASCSFCGRTEEAVEKLISGPNVYICDKCVRLCTGILDKKAPSTYEFKILKPKEIKEKLDEYIIGQENAKKT
ISVGVYNHYKRIRSKNKEADGIEFSKSNVLLFGPTGSGKTLIAKTLASILDVPFTIADATTLTEAGYVGEDVENIILRLL
QAADYDVAKAEQGIIYIDEIDKINRTTANVSITRDVSGEGVQQALLKIVEGTIANVPPKGGRKHPNQEYIKVNTENILFI
VGGAFVNLEKIIAKRLGRNTIGFDGSNREVVDPTQKSLLLSKVEPEDLIQFGMIPEFVGRFNSIANCNELQLPDLINILT
EPKNAFIKQFIAMFEAEGVKLQFTEDALAAIAQQAIEAGTGARALRLILENLMRELMYEIPSDETISEILIEKETVTEKK
PPIIKRHDQKIA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=324, Percent_Identity=48.4567901234568, Blast_Score=291, Evalue=1e-78,
Organism=Escherichia coli, GI1786642, Length=408, Percent_Identity=54.9019607843137, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=43.3962264150943, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=313, Percent_Identity=44.0894568690096, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71982905, Length=323, Percent_Identity=43.0340557275542, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71988663, Length=396, Percent_Identity=37.8787878787879, Blast_Score=240, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=39.6078431372549, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=421, Percent_Identity=41.0926365795724, Blast_Score=267, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24648291, Length=303, Percent_Identity=45.5445544554455, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24648289, Length=303, Percent_Identity=45.5445544554455, Blast_Score=279, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PARUW (Q6MBE8)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008376.1
- ProteinModelPortal:   Q6MBE8
- STRING:   Q6MBE8
- GeneID:   2779716
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1377
- NMPDR:   fig|264201.1.peg.1377
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   CPRO264201:PC1377-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45735; Mature: 45604

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKSLTKELASCSFCGRTEEAVEKLISGPNVYICDKCVRLCTGILDKKAPSTYEFKILK
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEC
PKEIKEKLDEYIIGQENAKKTISVGVYNHYKRIRSKNKEADGIEFSKSNVLLFGPTGSGK
HHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCC
TLIAKTLASILDVPFTIADATTLTEAGYVGEDVENIILRLLQAADYDVAKAEQGIIYIDE
HHHHHHHHHHHCCCCEECCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCCEEEEEC
IDKINRTTANVSITRDVSGEGVQQALLKIVEGTIANVPPKGGRKHPNQEYIKVNTENILF
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEE
IVGGAFVNLEKIIAKRLGRNTIGFDGSNREVVDPTQKSLLLSKVEPEDLIQFGMIPEFVG
EECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHH
RFNSIANCNELQLPDLINILTEPKNAFIKQFIAMFEAEGVKLQFTEDALAAIAQQAIEAG
HHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCC
TGARALRLILENLMRELMYEIPSDETISEILIEKETVTEKKPPIIKRHDQKIA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKKSLTKELASCSFCGRTEEAVEKLISGPNVYICDKCVRLCTGILDKKAPSTYEFKILK
CHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEC
PKEIKEKLDEYIIGQENAKKTISVGVYNHYKRIRSKNKEADGIEFSKSNVLLFGPTGSGK
HHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCC
TLIAKTLASILDVPFTIADATTLTEAGYVGEDVENIILRLLQAADYDVAKAEQGIIYIDE
HHHHHHHHHHHCCCCEECCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCCEEEEEC
IDKINRTTANVSITRDVSGEGVQQALLKIVEGTIANVPPKGGRKHPNQEYIKVNTENILF
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEE
IVGGAFVNLEKIIAKRLGRNTIGFDGSNREVVDPTQKSLLLSKVEPEDLIQFGMIPEFVG
EECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHH
RFNSIANCNELQLPDLINILTEPKNAFIKQFIAMFEAEGVKLQFTEDALAAIAQQAIEAG
HHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCC
TGARALRLILENLMRELMYEIPSDETISEILIEKETVTEKKPPIIKRHDQKIA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA