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The map label for this gene is tig

Identifier: 46447009

GI number: 46447009

Start: 1648434

End: 1649741

Strand: Direct

Name: tig

Synonym: pc1375

Alternate gene names: 46447009

Gene position: 1648434-1649741 (Clockwise)

Preceding gene: 46447003

Following gene: 46447010

Centisome position: 68.27

GC content: 37.08

Gene sequence:

>1308_bases
GTGTCAAATCAAGAGACTGAAGCTGGTTCAAAAACCATTAGTAATGATAATCTTAACGTTCAGATTACCCGAGGCACCCA
TTGTCAAGTCAAATTTGACATCACAGTAAAACCTGAAGCCGTTGTCGCTGCTTATCAAAAAGCTTTGAAAACGATCAATA
AAGAAATCAATATTCCAGGATTTCGGAAGGGAAAAGCTCCTCAGCAATTAATCCTAGAAAAATATGGGTCTAACGTTCAA
AAAGAATGTGTTGATATCGTCTTACAAACTGGATTCAATGATGCTTTACAACTCACTCATATCCACCCATTAAAAGACGG
CCATATAAAACGCCCTATCGTGCACTATTGCACTCAAGAAAAAGGAGCCCATTTTGTTTTAGAGTTTGAAGCACGTCCCA
CTATCCCCTCTGTTCAACCACAAGAATTACATTTACACCACCAAGCTCCTGTACAGGTGACAGACGAAGAACGAAAGAAT
GCTCTTGACCAAGTTCTTTTACAATTTACGACCTATCAACCAATTGAAGATCGTCCTGTTCAGGAAGGAGATTTTATCAA
TGTTGATGTCACAATTTTAGAAGAAACACCTCGTCTCATTATCGACAATCAACGCACTCAAGTTAATCAATCTGGCTTAC
CTTCTTGGATACAAGAAAAAGTCATTGGATTAAATGCGGGAGCTAGCGCTGAAGGAATGACTCAGCCTAACGAAAAATTT
CCGGATCCAGATTTTAAATCTGTTCCTTTTCGTGTAACTGTAAAAACGATATGGCAAGGAAACATGCCTGCGATTGATGA
CGAATTAGCTAAAAAAGTAGGTTTACAAACCGTTGATGAGTTATATCAAAAATTAAACGAACGTTTAGAACAAGAAGCTC
AAGAAGATATTTATAAACAACACATTCATCATTTAGAAGATCAGCTTATCGAAAAATATCCCTTCGATCTTCCCCTTTCT
TATATCGAATCCAATAAACAGGCACGTTTAGATGACTACTTGAAGCAATTAGGTCAAGAAAGTCAGCTTCCTCAAAATTA
CGAAGAAATTGAGAAAATGATCGAAAATAGCACGATACGAGGTCTTCAACTTTACTTCCTACTCCGTCGTGTGGCGGCAG
ATAACAAACTTGAAGTCTCGGAAGAAGAAGTTTCTCAAGAATTATCAAAGCAAATTGCTCTTATTCCTAGCGGAAAAAGT
CAAATTGATATTTATGGTGATAAATCGAAATTGCGTGAGCAGCTTTATAATTTAGCGTTAGATCGCAAAATTAAAAAATT
CTTACTAGATCAAGCACAATGGGTTTAA

Upstream 100 bases:

>100_bases
GGGTGTAGCTCAGTGGTAGAGCATCACGTTGCCAACGTGAGAGTCGTGAGTTCGAATCTCATCACCCGCTTTTATAAGAT
CTATAGCAAAGAGGTTTTCC

Downstream 100 bases:

>100_bases
TTATTAATTAAATTTTAGATACTGATTTAGGCAGGAAAATTTAAACGCAAAACTGGAAAAATCTAAATAGGAACCATTTG
AAAAATGCAAATTGACTAAA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSNQETEAGSKTISNDNLNVQITRGTHCQVKFDITVKPEAVVAAYQKALKTINKEINIPGFRKGKAPQQLILEKYGSNVQ
KECVDIVLQTGFNDALQLTHIHPLKDGHIKRPIVHYCTQEKGAHFVLEFEARPTIPSVQPQELHLHHQAPVQVTDEERKN
ALDQVLLQFTTYQPIEDRPVQEGDFINVDVTILEETPRLIIDNQRTQVNQSGLPSWIQEKVIGLNAGASAEGMTQPNEKF
PDPDFKSVPFRVTVKTIWQGNMPAIDDELAKKVGLQTVDELYQKLNERLEQEAQEDIYKQHIHHLEDQLIEKYPFDLPLS
YIESNKQARLDDYLKQLGQESQLPQNYEEIEKMIENSTIRGLQLYFLLRRVAADNKLEVSEEEVSQELSKQIALIPSGKS
QIDIYGDKSKLREQLYNLALDRKIKKFLLDQAQWV

Sequences:

>Translated_435_residues
MSNQETEAGSKTISNDNLNVQITRGTHCQVKFDITVKPEAVVAAYQKALKTINKEINIPGFRKGKAPQQLILEKYGSNVQ
KECVDIVLQTGFNDALQLTHIHPLKDGHIKRPIVHYCTQEKGAHFVLEFEARPTIPSVQPQELHLHHQAPVQVTDEERKN
ALDQVLLQFTTYQPIEDRPVQEGDFINVDVTILEETPRLIIDNQRTQVNQSGLPSWIQEKVIGLNAGASAEGMTQPNEKF
PDPDFKSVPFRVTVKTIWQGNMPAIDDELAKKVGLQTVDELYQKLNERLEQEAQEDIYKQHIHHLEDQLIEKYPFDLPLS
YIESNKQARLDDYLKQLGQESQLPQNYEEIEKMIENSTIRGLQLYFLLRRVAADNKLEVSEEEVSQELSKQIALIPSGKS
QIDIYGDKSKLREQLYNLALDRKIKKFLLDQAQWV
>Mature_434_residues
SNQETEAGSKTISNDNLNVQITRGTHCQVKFDITVKPEAVVAAYQKALKTINKEINIPGFRKGKAPQQLILEKYGSNVQK
ECVDIVLQTGFNDALQLTHIHPLKDGHIKRPIVHYCTQEKGAHFVLEFEARPTIPSVQPQELHLHHQAPVQVTDEERKNA
LDQVLLQFTTYQPIEDRPVQEGDFINVDVTILEETPRLIIDNQRTQVNQSGLPSWIQEKVIGLNAGASAEGMTQPNEKFP
DPDFKSVPFRVTVKTIWQGNMPAIDDELAKKVGLQTVDELYQKLNERLEQEAQEDIYKQHIHHLEDQLIEKYPFDLPLSY
IESNKQARLDDYLKQLGQESQLPQNYEEIEKMIENSTIRGLQLYFLLRRVAADNKLEVSEEEVSQELSKQIALIPSGKSQ
IDIYGDKSKLREQLYNLALDRKIKKFLLDQAQWV

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=427, Percent_Identity=22.7166276346604, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_PARUW (Q6MBF0)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008374.1
- ProteinModelPortal:   Q6MBF0
- STRING:   Q6MBF0
- GeneID:   2780384
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1375
- NMPDR:   fig|264201.1.peg.1375
- eggNOG:   COG0544
- OMA:   NARLIQY
- ProtClustDB:   PRK01490
- BioCyc:   CPRO264201:PC1375-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49876; Mature: 49745

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQETEAGSKTISNDNLNVQITRGTHCQVKFDITVKPEAVVAAYQKALKTINKEINIPG
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCC
FRKGKAPQQLILEKYGSNVQKECVDIVLQTGFNDALQLTHIHPLKDGHIKRPIVHYCTQE
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCC
KGAHFVLEFEARPTIPSVQPQELHLHHQAPVQVTDEERKNALDQVLLQFTTYQPIEDRPV
CCCEEEEEEECCCCCCCCCHHHEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCC
QEGDFINVDVTILEETPRLIIDNQRTQVNQSGLPSWIQEKVIGLNAGASAEGMTQPNEKF
CCCCEEEEEEEEECCCCCEEECCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
PDPDFKSVPFRVTVKTIWQGNMPAIDDELAKKVGLQTVDELYQKLNERLEQEAQEDIYKQ
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
HIHHLEDQLIEKYPFDLPLSYIESNKQARLDDYLKQLGQESQLPQNYEEIEKMIENSTIR
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCH
GLQLYFLLRRVAADNKLEVSEEEVSQELSKQIALIPSGKSQIDIYGDKSKLREQLYNLAL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHH
DRKIKKFLLDQAQWV
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNQETEAGSKTISNDNLNVQITRGTHCQVKFDITVKPEAVVAAYQKALKTINKEINIPG
CCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCC
FRKGKAPQQLILEKYGSNVQKECVDIVLQTGFNDALQLTHIHPLKDGHIKRPIVHYCTQE
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCC
KGAHFVLEFEARPTIPSVQPQELHLHHQAPVQVTDEERKNALDQVLLQFTTYQPIEDRPV
CCCEEEEEEECCCCCCCCCHHHEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCC
QEGDFINVDVTILEETPRLIIDNQRTQVNQSGLPSWIQEKVIGLNAGASAEGMTQPNEKF
CCCCEEEEEEEEECCCCCEEECCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
PDPDFKSVPFRVTVKTIWQGNMPAIDDELAKKVGLQTVDELYQKLNERLEQEAQEDIYKQ
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
HIHHLEDQLIEKYPFDLPLSYIESNKQARLDDYLKQLGQESQLPQNYEEIEKMIENSTIR
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCH
GLQLYFLLRRVAADNKLEVSEEEVSQELSKQIALIPSGKSQIDIYGDKSKLREQLYNLAL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHH
DRKIKKFLLDQAQWV
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA