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The map label for this gene is dhcR7

Identifier: 46446854

GI number: 46446854

Start: 1451379

End: 1452686

Strand: Direct

Name: dhcR7

Synonym: pc1220

Alternate gene names: NA

Gene position: 1451379-1452686 (Clockwise)

Preceding gene: 46446853

Following gene: 46446855

Centisome position: 60.11

GC content: 36.85

Gene sequence:

>1308_bases
ATGTTGCCAACACAAACATCTTTTTTTCGACAAACTTTTGGTCCTTTGATTCTTTTATTACTTTGCCCTCCCACTGTGTT
TGCTTTTTGGTACACCAATACTTATTTAGAAGGCTCTCTTTTTCGTTTTACAGAATTTGCTTGGCAACAAGGTTTTCTTT
CCACATTAAAAACGATTTGGTTTCCTTATTTTTTTGGAACTTCTATAGCCTGGACAATGTTAGTAATTCTTGCTTCTCTT
CAGCTTATTTTAATGCGCATTCTGCCTGGAGAGCGCTATGAGGGACCAATCACTCCTGCTGGACACGTTCCCCTTTATAA
GGCAAATGGGTTTTCTGCTTTTATTGTTACGATCTCCATTTTTTTAATCGCATCCTATTATTACCAACTGTTTGCTCCAA
CAATTATTTATGACAATTTTCCGGGTCTACTTGGAGCCTTGAATATATTTAGTTTATGCTTTTGCTTTTTTCTTGTCCTA
AAAGGGCATTATTTTCCCTCAAATGGCGATGTTGGAGGATCGGGAAATATCATTTTTGATTATTATTGGGGAATGGAACT
TTACCCTCGCTTACTCGGTTGGGATATTAAGCAATTTACTAACTGTCGATTTGGAATGATGAGCTGGGCTTTAATTGTGA
TTTCTTTTGCTGCTAAACAACAACAGCTTGATGGATTAAGCGATTCCATGTTTGTTGCAGTAGCTCTCCAACTGATTTAT
ATTACAAAATTTTTTATCTGGGAACCAGGCTACCTTCGTTCGTTAGATATCATGCACGACAGAGCTGGTTACTATATTTG
TTGGGGATGCCTTGTTTGGGTTCCAGGTATTTATACATCCCCCACTCTCTATTTAGTTGATCACCCCAATCACTTAGGTT
TAGCTCTATCCAGTTTATTATTTGTCGTTGGGGTGATTGGAATTTTAGTTAACTATTTGGCAGATCGCCAAAGACAATTA
GTGAGAAAAAATCAAGGAAATTGCCGTATTTGGGGGAAAGAACCCATTTTGACAGTTGCAAAATATACAACACAAACAGG
AGAATCGAAACAAAATCTTTTACTTGCCTCTGGCTGGTGGGGTTTGTCTAGACATTTTCATTATCTTCCTGAACTGCTTG
GAGCCTTTTGTTGGAGTGCACCAGCTCTATTTGAGAATTTTCTACCCTATTTTTATTTTGTTTTCTTAACCATTTTATTA
ACTGATCGCGCCTTTAGAGATGATCAACGCTGCTCAAAAAAATATGGGGAAGATTGGAAAATTTATTGTCAAAGAGTCCC
TTATAAAATTATTCCCTTTGTTATTTAA

Upstream 100 bases:

>100_bases
AGATTTTTCCGAATTTTTAATTGAGTAATTCTTATTGAAATGCTATGCATTACCAAACATATTCTAGAAAAAATTAGTAA
ATTCTCTCTCGCGAGGCCAC

Downstream 100 bases:

>100_bases
GACATGGATATATTCTTAAATGCAGATTTTGTTTGTTACATCTAAATGAATGAACTCATCCGTTGCATTTATGGTTAGGG
ATTTTTCTATAAGATTGATC

Product: putative 7-dehydrocholesterol reductase

Products: NA

Alternate protein names: Delta(24(24(1)))-Sterol Reductase

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLPTQTSFFRQTFGPLILLLLCPPTVFAFWYTNTYLEGSLFRFTEFAWQQGFLSTLKTIWFPYFFGTSIAWTMLVILASL
QLILMRILPGERYEGPITPAGHVPLYKANGFSAFIVTISIFLIASYYYQLFAPTIIYDNFPGLLGALNIFSLCFCFFLVL
KGHYFPSNGDVGGSGNIIFDYYWGMELYPRLLGWDIKQFTNCRFGMMSWALIVISFAAKQQQLDGLSDSMFVAVALQLIY
ITKFFIWEPGYLRSLDIMHDRAGYYICWGCLVWVPGIYTSPTLYLVDHPNHLGLALSSLLFVVGVIGILVNYLADRQRQL
VRKNQGNCRIWGKEPILTVAKYTTQTGESKQNLLLASGWWGLSRHFHYLPELLGAFCWSAPALFENFLPYFYFVFLTILL
TDRAFRDDQRCSKKYGEDWKIYCQRVPYKIIPFVI

Sequences:

>Translated_435_residues
MLPTQTSFFRQTFGPLILLLLCPPTVFAFWYTNTYLEGSLFRFTEFAWQQGFLSTLKTIWFPYFFGTSIAWTMLVILASL
QLILMRILPGERYEGPITPAGHVPLYKANGFSAFIVTISIFLIASYYYQLFAPTIIYDNFPGLLGALNIFSLCFCFFLVL
KGHYFPSNGDVGGSGNIIFDYYWGMELYPRLLGWDIKQFTNCRFGMMSWALIVISFAAKQQQLDGLSDSMFVAVALQLIY
ITKFFIWEPGYLRSLDIMHDRAGYYICWGCLVWVPGIYTSPTLYLVDHPNHLGLALSSLLFVVGVIGILVNYLADRQRQL
VRKNQGNCRIWGKEPILTVAKYTTQTGESKQNLLLASGWWGLSRHFHYLPELLGAFCWSAPALFENFLPYFYFVFLTILL
TDRAFRDDQRCSKKYGEDWKIYCQRVPYKIIPFVI
>Mature_435_residues
MLPTQTSFFRQTFGPLILLLLCPPTVFAFWYTNTYLEGSLFRFTEFAWQQGFLSTLKTIWFPYFFGTSIAWTMLVILASL
QLILMRILPGERYEGPITPAGHVPLYKANGFSAFIVTISIFLIASYYYQLFAPTIIYDNFPGLLGALNIFSLCFCFFLVL
KGHYFPSNGDVGGSGNIIFDYYWGMELYPRLLGWDIKQFTNCRFGMMSWALIVISFAAKQQQLDGLSDSMFVAVALQLIY
ITKFFIWEPGYLRSLDIMHDRAGYYICWGCLVWVPGIYTSPTLYLVDHPNHLGLALSSLLFVVGVIGILVNYLADRQRQL
VRKNQGNCRIWGKEPILTVAKYTTQTGESKQNLLLASGWWGLSRHFHYLPELLGAFCWSAPALFENFLPYFYFVFLTILL
TDRAFRDDQRCSKKYGEDWKIYCQRVPYKIIPFVI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI255308875, Length=365, Percent_Identity=38.0821917808219, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI119943112, Length=365, Percent_Identity=38.0821917808219, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI37595752, Length=386, Percent_Identity=33.6787564766839, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI37595750, Length=386, Percent_Identity=33.6787564766839, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI117414150, Length=336, Percent_Identity=33.6309523809524, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71981758, Length=423, Percent_Identity=28.8416075650118, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324049, Length=394, Percent_Identity=29.4416243654822, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321426, Length=378, Percent_Identity=26.7195767195767, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50213; Mature: 50213

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS01017 STEROL_REDUCT_1 ; PS01018 STEROL_REDUCT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTQTSFFRQTFGPLILLLLCPPTVFAFWYTNTYLEGSLFRFTEFAWQQGFLSTLKTIW
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FPYFFGTSIAWTMLVILASLQLILMRILPGERYEGPITPAGHVPLYKANGFSAFIVTISI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHH
FLIASYYYQLFAPTIIYDNFPGLLGALNIFSLCFCFFLVLKGHYFPSNGDVGGSGNIIFD
HHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
YYWGMELYPRLLGWDIKQFTNCRFGMMSWALIVISFAAKQQQLDGLSDSMFVAVALQLIY
EECCHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ITKFFIWEPGYLRSLDIMHDRAGYYICWGCLVWVPGIYTSPTLYLVDHPNHLGLALSSLL
HHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHH
FVVGVIGILVNYLADRQRQLVRKNQGNCRIWGKEPILTVAKYTTQTGESKQNLLLASGWW
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCCCCEEEEECCH
GLSRHFHYLPELLGAFCWSAPALFENFLPYFYFVFLTILLTDRAFRDDQRCSKKYGEDWK
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
IYCQRVPYKIIPFVI
HHHHHCCHHHCCCCC
>Mature Secondary Structure
MLPTQTSFFRQTFGPLILLLLCPPTVFAFWYTNTYLEGSLFRFTEFAWQQGFLSTLKTIW
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FPYFFGTSIAWTMLVILASLQLILMRILPGERYEGPITPAGHVPLYKANGFSAFIVTISI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHH
FLIASYYYQLFAPTIIYDNFPGLLGALNIFSLCFCFFLVLKGHYFPSNGDVGGSGNIIFD
HHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
YYWGMELYPRLLGWDIKQFTNCRFGMMSWALIVISFAAKQQQLDGLSDSMFVAVALQLIY
EECCHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ITKFFIWEPGYLRSLDIMHDRAGYYICWGCLVWVPGIYTSPTLYLVDHPNHLGLALSSLL
HHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHH
FVVGVIGILVNYLADRQRQLVRKNQGNCRIWGKEPILTVAKYTTQTGESKQNLLLASGWW
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCCCCEEEEECCH
GLSRHFHYLPELLGAFCWSAPALFENFLPYFYFVFLTILLTDRAFRDDQRCSKKYGEDWK
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
IYCQRVPYKIIPFVI
HHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA