Click here to switch to the map view.

The map label for this gene is groES [H]

Identifier: 46446813

GI number: 46446813

Start: 1406041

End: 1406361

Strand: Direct

Name: groES [H]

Synonym: pc1179

Alternate gene names: 46446813

Gene position: 1406041-1406361 (Clockwise)

Preceding gene: 46446812

Following gene: 46446814

Centisome position: 58.23

GC content: 39.56

Gene sequence:

>321_bases
ATGACACAAACTCAAACAGTCTCTCAAATCACGAAACTAAAACCTTTAGGAAATCGCGTTCTTGTTCGCCGCTTAGCCGC
CGAAGAGAAGTTAAAAGGAGGAATCATTCTCCCCGACACTGCAAAAAAGAAACAGGAACAGGCAGAAGTCATAGCAATTG
GAACAGGTAAAAAAGATAAAAACGGTACCTTAGTTCCCATGCCTGTCAAAATCGGTGATGTGATCCTTATGGAAAAATAT
TCGGGTCAAGAAATAACTCTAAATGATGAGGAGTTAGTGATTCTTCGTGCCGATGATATCATTGCCATTGTAGAAAAATA
A

Upstream 100 bases:

>100_bases
AAAAAAACTTAGCTGGTTATATTGACTACCTCAATCACCATTAGATAGTTAGTGCGGAATCTAACATTAACTTTTAACTT
AATAAATATAGGAGATCCCT

Downstream 100 bases:

>100_bases
TTAATTATTCACATTCACAGGAGATTTCAAATGGCCGCTAAAATTATTAAATTTAAAGAAGATGCCAGACAAAAAATTTT
AAAAGGTGTCCGTACTTTAG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTQTQTVSQITKLKPLGNRVLVRRLAAEEKLKGGIILPDTAKKKQEQAEVIAIGTGKKDKNGTLVPMPVKIGDVILMEKY
SGQEITLNDEELVILRADDIIAIVEK

Sequences:

>Translated_106_residues
MTQTQTVSQITKLKPLGNRVLVRRLAAEEKLKGGIILPDTAKKKQEQAEVIAIGTGKKDKNGTLVPMPVKIGDVILMEKY
SGQEITLNDEELVILRADDIIAIVEK
>Mature_105_residues
TQTQTVSQITKLKPLGNRVLVRRLAAEEKLKGGIILPDTAKKKQEQAEVIAIGTGKKDKNGTLVPMPVKIGDVILMEKYS
GQEITLNDEELVILRADDIIAIVEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=93, Percent_Identity=43.010752688172, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=40, Blast_Score=71, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555568, Length=106, Percent_Identity=38.6792452830189, Blast_Score=81, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=101, Percent_Identity=35.6435643564356, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 11650; Mature: 11519

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTQTVSQITKLKPLGNRVLVRRLAAEEKLKGGIILPDTAKKKQEQAEVIAIGTGKKDK
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEEEECCCCCC
NGTLVPMPVKIGDVILMEKYSGQEITLNDEELVILRADDIIAIVEK
CCCEEEECCCCCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEEC
>Mature Secondary Structure 
TQTQTVSQITKLKPLGNRVLVRRLAAEEKLKGGIILPDTAKKKQEQAEVIAIGTGKKDK
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEEEECCCCCC
NGTLVPMPVKIGDVILMEKYSGQEITLNDEELVILRADDIIAIVEK
CCCEEEECCCCCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1682266; 10192388; 10684935; 10871362 [H]