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The map label for this gene is fusA [H]

Identifier: 46446750

GI number: 46446750

Start: 1336275

End: 1338095

Strand: Direct

Name: fusA [H]

Synonym: pc1116

Alternate gene names: 46446750

Gene position: 1336275-1338095 (Clockwise)

Preceding gene: 46446748

Following gene: 46446754

Centisome position: 55.34

GC content: 39.54

Gene sequence:

>1821_bases
ATGTATTCTCCTGAAAAAATCCGTAATATTGCGATCATTGCGCACATTGACCACGGTAAAACAACATTGTTAGATGCTTT
GCTTAAACAGTCTAAAATTTTTCGCGATAATCAACAAGTTCGCGAACGCGTTATGGACTCATATGATCAAGAACAAGAAC
GTGGAATTACTATTTTTGCTAAACATACGTCTGTTTACTTTGATGATTTCAAAATTAATATTATTGACACTCCAGGACAC
GCTGATTTCTCAGGTGAAGTCGAACGTATTTTAGGAATGGTAGATTCAGTCCTACTACTTGTAGATGCCCAAGAGGGACC
GATGCCTCAAACCCGCTTTGTTCTTTCTAAATCATTAAAAATGGGCATTAAACCTATTGTCGTCTTAAATAAAATTGACC
GACCTCATGCCAACCCAGATAGAGTATTAGACTTAACATTTGATCTATTTAGTGAACTTGGTGCAACAGATGAACAACTT
GATTTCCGCTATTGCTATGCATCAGGGTTATCAGGATTTGCGATGCACCACATGCACGATACACATAAAGATATGCGTCC
TTTATTTGAACTTATTACTTACGCCGTACAACAGCCTAAAGGTAGCCTCGAAAATCCTTTCTTAATGCATGTATCTACAA
TTACTTATGATGATTATGTTGGCCGTCAAGCTTGTGGAAAAATTTTAGAAGGGACTGTCAAAAAAGGACAGCAGCTCATT
CATATCGATGAAAATGGGGTGGAAACCAAATGCACAATTACCCGTATTGAAGGGCATTTAGGAATTGAAAAAGTTGAAAT
GGAAGAAGCTGGCGTAGGCGACATTGTCATCTTATCAGGTATTCCAGAAGTGACAATTGGTGACACAATTTGCGATCCTA
AAAAAATTGTTCGACTTCCTCGTATTAAGCTAGATGAACCTACAGTTTCCGTCGATATGACAGTTAATAATAGCCCATTT
GTTGGTCGTAGTGGTAAACACGTTACAATGAATAAAATTCGCGATCGCTTAGAAAAAGAAAAACGCGCTAATATTTCCCT
CAGAATCGAAGATGAGAGCGGAGATCAAGATAAAATTACTGTATCAGGTCGCGGAGAGCTTCACTTAGCTGTTTTAGTAG
AAGCTATGCGCCGTGAACAATACGAGTTTAGCATTTCTAAACCTCGAGTTATTATTAAAGAAGTCAATGGCGAGAAATAC
GAACCGATTGAACGGGTACATATTGAGGTTCCACAAGACTACTCAGGAACAGTGATTGAAGAACTTTCCCGACGCAAAGG
AGAACTTCAACTACTAGATACAGATGAAAATGGAATTACTGCTATAGACTTTTTGATTCCTACAAGAGGGCTCATGGGTT
ATCGCAATGACTTTTTAACCGCGACTAGAGGTCTCGGAATTTTGACGTCTGTTTTTGAAAACTTTTCTCCTTGGAAAGGA
ACTATTCCTGGTCGTACAAGGGGTGTCTTACTCTCTAATGGACCAGGCAAAACCAGCGGTTACGCTTGCTTTAATTTACA
AGATCGTGGAGTCATGTTTGTTGCTCCCGGGGATGAGGTTTACGAAGGAATGGTCGTTGGAGAGAATAGTCGCGATAATG
ACTTAGTGGTCAACGTAACTAAAGGAAAACAATTGACAAACGTCAGAGCTTCTGGAAGTGATGAAAACATTATCTTAATC
CCTGCTCGCCGGTTTACTCTTGAACAGGCAATTGATTATATCCAAGATGATGAATTAATCGAAGTCACTCCTGACAGCAT
CCGTATGCGAAAACGTCATCTTTTAGAGAATGACCGCAAACGAGCTGGTGGAAAAGCCTAA

Upstream 100 bases:

>100_bases
TTTTTTAAATTCTGAAAGCTTATCATTTATGATTTATATAAAATGTTTGAATTATTAACCTGGCTGAAAAGTTTAGCCTC
ATAAACTAAAAGATCACTTT

Downstream 100 bases:

>100_bases
CTTTTTTTAACTCATCTTACCATGTGTAAGATGAGTTAAAATTTTAAATAAAAGGCTTACTTTCTTTTTTTAGGCTAATG
GCTCAAAGTAACTCGTGATG

Product: putative elongation factor G (EF-G), fusA

Products: NA

Alternate protein names: Tyrosine phosphorylated protein A [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MYSPEKIRNIAIIAHIDHGKTTLLDALLKQSKIFRDNQQVRERVMDSYDQEQERGITIFAKHTSVYFDDFKINIIDTPGH
ADFSGEVERILGMVDSVLLLVDAQEGPMPQTRFVLSKSLKMGIKPIVVLNKIDRPHANPDRVLDLTFDLFSELGATDEQL
DFRYCYASGLSGFAMHHMHDTHKDMRPLFELITYAVQQPKGSLENPFLMHVSTITYDDYVGRQACGKILEGTVKKGQQLI
HIDENGVETKCTITRIEGHLGIEKVEMEEAGVGDIVILSGIPEVTIGDTICDPKKIVRLPRIKLDEPTVSVDMTVNNSPF
VGRSGKHVTMNKIRDRLEKEKRANISLRIEDESGDQDKITVSGRGELHLAVLVEAMRREQYEFSISKPRVIIKEVNGEKY
EPIERVHIEVPQDYSGTVIEELSRRKGELQLLDTDENGITAIDFLIPTRGLMGYRNDFLTATRGLGILTSVFENFSPWKG
TIPGRTRGVLLSNGPGKTSGYACFNLQDRGVMFVAPGDEVYEGMVVGENSRDNDLVVNVTKGKQLTNVRASGSDENIILI
PARRFTLEQAIDYIQDDELIEVTPDSIRMRKRHLLENDRKRAGGKA

Sequences:

>Translated_606_residues
MYSPEKIRNIAIIAHIDHGKTTLLDALLKQSKIFRDNQQVRERVMDSYDQEQERGITIFAKHTSVYFDDFKINIIDTPGH
ADFSGEVERILGMVDSVLLLVDAQEGPMPQTRFVLSKSLKMGIKPIVVLNKIDRPHANPDRVLDLTFDLFSELGATDEQL
DFRYCYASGLSGFAMHHMHDTHKDMRPLFELITYAVQQPKGSLENPFLMHVSTITYDDYVGRQACGKILEGTVKKGQQLI
HIDENGVETKCTITRIEGHLGIEKVEMEEAGVGDIVILSGIPEVTIGDTICDPKKIVRLPRIKLDEPTVSVDMTVNNSPF
VGRSGKHVTMNKIRDRLEKEKRANISLRIEDESGDQDKITVSGRGELHLAVLVEAMRREQYEFSISKPRVIIKEVNGEKY
EPIERVHIEVPQDYSGTVIEELSRRKGELQLLDTDENGITAIDFLIPTRGLMGYRNDFLTATRGLGILTSVFENFSPWKG
TIPGRTRGVLLSNGPGKTSGYACFNLQDRGVMFVAPGDEVYEGMVVGENSRDNDLVVNVTKGKQLTNVRASGSDENIILI
PARRFTLEQAIDYIQDDELIEVTPDSIRMRKRHLLENDRKRAGGKA
>Mature_606_residues
MYSPEKIRNIAIIAHIDHGKTTLLDALLKQSKIFRDNQQVRERVMDSYDQEQERGITIFAKHTSVYFDDFKINIIDTPGH
ADFSGEVERILGMVDSVLLLVDAQEGPMPQTRFVLSKSLKMGIKPIVVLNKIDRPHANPDRVLDLTFDLFSELGATDEQL
DFRYCYASGLSGFAMHHMHDTHKDMRPLFELITYAVQQPKGSLENPFLMHVSTITYDDYVGRQACGKILEGTVKKGQQLI
HIDENGVETKCTITRIEGHLGIEKVEMEEAGVGDIVILSGIPEVTIGDTICDPKKIVRLPRIKLDEPTVSVDMTVNNSPF
VGRSGKHVTMNKIRDRLEKEKRANISLRIEDESGDQDKITVSGRGELHLAVLVEAMRREQYEFSISKPRVIIKEVNGEKY
EPIERVHIEVPQDYSGTVIEELSRRKGELQLLDTDENGITAIDFLIPTRGLMGYRNDFLTATRGLGILTSVFENFSPWKG
TIPGRTRGVLLSNGPGKTSGYACFNLQDRGVMFVAPGDEVYEGMVVGENSRDNDLVVNVTKGKQLTNVRASGSDENIILI
PARRFTLEQAIDYIQDDELIEVTPDSIRMRKRHLLENDRKRAGGKA

Specific function: Probably interacts with the ribosomes in a GTP dependent manner. GTPase that mediates interactions between enteropathogenic E.coli (EPEC) and epithelial cells [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=492, Percent_Identity=27.6422764227642, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=43.9393939393939, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI18390331, Length=144, Percent_Identity=42.3611111111111, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4503483, Length=144, Percent_Identity=38.1944444444444, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=41.8181818181818, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=41.8181818181818, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=41.8181818181818, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25306287, Length=135, Percent_Identity=41.4814814814815, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI19923640, Length=135, Percent_Identity=41.4814814814815, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI25306283, Length=135, Percent_Identity=41.4814814814815, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI217272894, Length=149, Percent_Identity=36.241610738255, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI217272892, Length=149, Percent_Identity=36.241610738255, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI34147630, Length=233, Percent_Identity=28.755364806867, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI223555963, Length=323, Percent_Identity=26.9349845201238, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI5729864, Length=323, Percent_Identity=26.9349845201238, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI94966752, Length=81, Percent_Identity=43.2098765432099, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI53729339, Length=253, Percent_Identity=27.6679841897233, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI53729337, Length=253, Percent_Identity=27.6679841897233, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=599, Percent_Identity=52.754590984975, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=510, Percent_Identity=28.2352941176471, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=37.8378378378378, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789737, Length=323, Percent_Identity=26.0061919504644, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=32.4137931034483, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790412, Length=323, Percent_Identity=26.0061919504644, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789559, Length=292, Percent_Identity=27.7397260273973, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557151, Length=290, Percent_Identity=31.3793103448276, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=42.3076923076923, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=42.3076923076923, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17506493, Length=156, Percent_Identity=35.8974358974359, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=145, Percent_Identity=40.6896551724138, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17556745, Length=141, Percent_Identity=37.5886524822695, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=140, Percent_Identity=35, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=261, Percent_Identity=27.2030651340996, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323320, Length=520, Percent_Identity=26.7307692307692, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324707, Length=144, Percent_Identity=41.6666666666667, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=144, Percent_Identity=41.6666666666667, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323098, Length=148, Percent_Identity=39.1891891891892, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=145, Percent_Identity=41.3793103448276, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324761, Length=280, Percent_Identity=28.9285714285714, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=133, Percent_Identity=42.8571428571429, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322675, Length=143, Percent_Identity=31.4685314685315, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI78706572, Length=516, Percent_Identity=25.968992248062, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=41.726618705036, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585711, Length=148, Percent_Identity=39.1891891891892, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585713, Length=148, Percent_Identity=39.1891891891892, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585709, Length=148, Percent_Identity=39.1891891891892, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582462, Length=144, Percent_Identity=42.3611111111111, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357743, Length=197, Percent_Identity=33.502538071066, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363316, Length=330, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17864358, Length=330, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221458488, Length=140, Percent_Identity=40.7142857142857, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19922690, Length=243, Percent_Identity=30.0411522633745, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19921738, Length=241, Percent_Identity=26.5560165975104, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68178; Mature: 68178

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSPEKIRNIAIIAHIDHGKTTLLDALLKQSKIFRDNQQVRERVMDSYDQEQERGITIFA
CCCHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCEEEEE
KHTSVYFDDFKINIIDTPGHADFSGEVERILGMVDSVLLLVDAQEGPMPQTRFVLSKSLK
EEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHH
MGIKPIVVLNKIDRPHANPDRVLDLTFDLFSELGATDEQLDFRYCYASGLSGFAMHHMHD
CCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHCCCCHHCEEEEEECCCCCHHHHHHHHH
THKDMRPLFELITYAVQQPKGSLENPFLMHVSTITYDDYVGRQACGKILEGTVKKGQQLI
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEHHHCCHHHHHHHHHHHHHCCCEEE
HIDENGVETKCTITRIEGHLGIEKVEMEEAGVGDIVILSGIPEVTIGDTICDPKKIVRLP
EECCCCCEEEEEEEEECCCCCCEEEEHHHCCCCCEEEECCCCCEECCCCCCCHHHHHHCC
RIKLDEPTVSVDMTVNNSPFVGRSGKHVTMNKIRDRLEKEKRANISLRIEDESGDQDKIT
CEEECCCEEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCEEE
VSGRGELHLAVLVEAMRREQYEFSISKPRVIIKEVNGEKYEPIERVHIEVPQDYSGTVIE
ECCCCCEEHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ELSRRKGELQLLDTDENGITAIDFLIPTRGLMGYRNDFLTATRGLGILTSVFENFSPWKG
HHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCC
TIPGRTRGVLLSNGPGKTSGYACFNLQDRGVMFVAPGDEVYEGMVVGENSRDNDLVVNVT
CCCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCHHHHCCEEECCCCCCCCEEEEEE
KGKQLTNVRASGSDENIILIPARRFTLEQAIDYIQDDELIEVTPDSIRMRKRHLLENDRK
CCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
RAGGKA
HCCCCC
>Mature Secondary Structure
MYSPEKIRNIAIIAHIDHGKTTLLDALLKQSKIFRDNQQVRERVMDSYDQEQERGITIFA
CCCHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCEEEEE
KHTSVYFDDFKINIIDTPGHADFSGEVERILGMVDSVLLLVDAQEGPMPQTRFVLSKSLK
EEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHH
MGIKPIVVLNKIDRPHANPDRVLDLTFDLFSELGATDEQLDFRYCYASGLSGFAMHHMHD
CCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHCCCCHHCEEEEEECCCCCHHHHHHHHH
THKDMRPLFELITYAVQQPKGSLENPFLMHVSTITYDDYVGRQACGKILEGTVKKGQQLI
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEHHHCCHHHHHHHHHHHHHCCCEEE
HIDENGVETKCTITRIEGHLGIEKVEMEEAGVGDIVILSGIPEVTIGDTICDPKKIVRLP
EECCCCCEEEEEEEEECCCCCCEEEEHHHCCCCCEEEECCCCCEECCCCCCCHHHHHHCC
RIKLDEPTVSVDMTVNNSPFVGRSGKHVTMNKIRDRLEKEKRANISLRIEDESGDQDKIT
CEEECCCEEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCEEE
VSGRGELHLAVLVEAMRREQYEFSISKPRVIIKEVNGEKYEPIERVHIEVPQDYSGTVIE
ECCCCCEEHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ELSRRKGELQLLDTDENGITAIDFLIPTRGLMGYRNDFLTATRGLGILTSVFENFSPWKG
HHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCC
TIPGRTRGVLLSNGPGKTSGYACFNLQDRGVMFVAPGDEVYEGMVVGENSRDNDLVVNVT
CCCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCHHHHCCEEECCCCCCCCEEEEEE
KGKQLTNVRASGSDENIILIPARRFTLEQAIDYIQDDELIEVTPDSIRMRKRHLLENDRK
CCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
RAGGKA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9622352 [H]