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The map label for this gene is ytfL [C]

Identifier: 46446754

GI number: 46446754

Start: 1344242

End: 1345501

Strand: Direct

Name: ytfL [C]

Synonym: pc1120

Alternate gene names: 46446754

Gene position: 1344242-1345501 (Clockwise)

Preceding gene: 46446750

Following gene: 46446755

Centisome position: 55.67

GC content: 35.87

Gene sequence:

>1260_bases
ATGCTTTTTAACAATCAAATAATAATCATGGCAGCTCTAATATTCTATTTCGTCTTTTCTCATTCTGTTTCATTTACTTG
TTCCATTTTAGAGGCAGTCTTACTCTGTTGCACGAATGGTTACATTGGACTTTTAAAGAAAAAAAAACCCAAAGCTGGAA
AAATTCTAGAAGAACTTAAACATCGAATTGATCGCCCCCTAGCAGCCATTTTGACTCTAAATACGTCTGCCCACACATTT
GGGGCGGCGGGAGTAGGTGCGAAAGTGGTAGAAATTTTTGGCGATCATACTTTAGCCTTTGCTTCTATTGTATTGACTTT
AACAATGCTAATTGCAACTGAAATGATCCCAAAAACTTTTGGGGCTCTTTACTGGAAAAAACTTGCTCCTGTAAGTGCTT
ACTGCATACAATTTTTAATTTGGGTTACCTATCCATTTGTAGTTTCGTTCGAGTACATTGCGAAATTGCTTGCTAGGGGT
AAAACTCATGACAAAATTACTGAAGAAGAAATTAAACTTATTTTAGAAGAAGGCTCTCAAGCAGGTGTGATTAGAGAAGC
AGAACATGATATGGTTGAAAGCATTTTTCGACTTGGAAATAGACGCGTGGGAATTCTTATGATTCCTCGAATGGATATCG
AATGGTTAGACTTAAATCATCATACAGAAGAGCTTCTCCAACAAATCAACATTTCTCCACATAATCGCTTTCCTGTTTGC
GATGGAGAATTAGATAAAGTTATCGGTCTAGTTACCACAAAAGATGTCCTCAATGAAATTTTAAAAACTGGAAAATTTGA
TTTAAAAACTCTTGTTAAAGCCCCTTTGTTTGTACCTGAAAATATGCGCGTGGTTCAATTATTGGACTTATTTAAAAAAA
CTCCTGATCATATAGCACTTGTCACTGATGAGTATGGAGGAGTACAAGGGCTTATTACATTGCATGATGTGTTAGAATCC
ATTGTTGGCGATGTACCCTCTACTTCTATTTTACCAGAAACACAAATCATTCAACGAAAAGATGGCTCTTGGTTAGTTGA
TGGAATGCTACCAATAGATGAACTAAAAGAACAATTTGATTTTGATAGTCTTCCTGAAGAAGAAAAAGGAACTTATCGAA
CACTCGGTGGGTTTTGTATGCGACAAATCGGAAGCATTCCTAATATTGGAGATACTTTTACTTGGCAAAAATTCCGCTTT
CGAGTTGTAAAAATGAATGGAAGGCGTGTAGAAAAAGTACTCATTCATTATCTTTCTTAA

Upstream 100 bases:

>100_bases
TTTCTAAACAAACAATAAAATTTGAGGATTAGCAAATTGTTAAATTTTCGTAGATTGTAAAATTTAAGTTTTTTTCTGAA
ACTCTAATTTTTCAATTTCT

Downstream 100 bases:

>100_bases
AGAAATTATAGATATGGAGAAAATTCAACAACTAATAAAGATTCTTCAAAACATTGATCAGCAGCCTTATCCAAGTCATT
CACGCATTCATGCCTTGTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLFNNQIIIMAALIFYFVFSHSVSFTCSILEAVLLCCTNGYIGLLKKKKPKAGKILEELKHRIDRPLAAILTLNTSAHTF
GAAGVGAKVVEIFGDHTLAFASIVLTLTMLIATEMIPKTFGALYWKKLAPVSAYCIQFLIWVTYPFVVSFEYIAKLLARG
KTHDKITEEEIKLILEEGSQAGVIREAEHDMVESIFRLGNRRVGILMIPRMDIEWLDLNHHTEELLQQINISPHNRFPVC
DGELDKVIGLVTTKDVLNEILKTGKFDLKTLVKAPLFVPENMRVVQLLDLFKKTPDHIALVTDEYGGVQGLITLHDVLES
IVGDVPSTSILPETQIIQRKDGSWLVDGMLPIDELKEQFDFDSLPEEEKGTYRTLGGFCMRQIGSIPNIGDTFTWQKFRF
RVVKMNGRRVEKVLIHYLS

Sequences:

>Translated_419_residues
MLFNNQIIIMAALIFYFVFSHSVSFTCSILEAVLLCCTNGYIGLLKKKKPKAGKILEELKHRIDRPLAAILTLNTSAHTF
GAAGVGAKVVEIFGDHTLAFASIVLTLTMLIATEMIPKTFGALYWKKLAPVSAYCIQFLIWVTYPFVVSFEYIAKLLARG
KTHDKITEEEIKLILEEGSQAGVIREAEHDMVESIFRLGNRRVGILMIPRMDIEWLDLNHHTEELLQQINISPHNRFPVC
DGELDKVIGLVTTKDVLNEILKTGKFDLKTLVKAPLFVPENMRVVQLLDLFKKTPDHIALVTDEYGGVQGLITLHDVLES
IVGDVPSTSILPETQIIQRKDGSWLVDGMLPIDELKEQFDFDSLPEEEKGTYRTLGGFCMRQIGSIPNIGDTFTWQKFRF
RVVKMNGRRVEKVLIHYLS
>Mature_419_residues
MLFNNQIIIMAALIFYFVFSHSVSFTCSILEAVLLCCTNGYIGLLKKKKPKAGKILEELKHRIDRPLAAILTLNTSAHTF
GAAGVGAKVVEIFGDHTLAFASIVLTLTMLIATEMIPKTFGALYWKKLAPVSAYCIQFLIWVTYPFVVSFEYIAKLLARG
KTHDKITEEEIKLILEEGSQAGVIREAEHDMVESIFRLGNRRVGILMIPRMDIEWLDLNHHTEELLQQINISPHNRFPVC
DGELDKVIGLVTTKDVLNEILKTGKFDLKTLVKAPLFVPENMRVVQLLDLFKKTPDHIALVTDEYGGVQGLITLHDVLES
IVGDVPSTSILPETQIIQRKDGSWLVDGMLPIDELKEQFDFDSLPEEEKGTYRTLGGFCMRQIGSIPNIGDTFTWQKFRF
RVVKMNGRRVEKVLIHYLS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=284, Percent_Identity=25, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1790664, Length=321, Percent_Identity=31.7757009345794, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI145693175, Length=359, Percent_Identity=29.5264623955432, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082033, Length=268, Percent_Identity=30.9701492537313, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=32.9059829059829, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1786879, Length=249, Percent_Identity=30.1204819277108, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47320; Mature: 47320

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNNQIIIMAALIFYFVFSHSVSFTCSILEAVLLCCTNGYIGLLKKKKPKAGKILEELK
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEHCCCCCCHHHHHHHHH
HRIDRPLAAILTLNTSAHTFGAAGVGAKVVEIFGDHTLAFASIVLTLTMLIATEMIPKTF
HHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GALYWKKLAPVSAYCIQFLIWVTYPFVVSFEYIAKLLARGKTHDKITEEEIKLILEEGSQ
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
AGVIREAEHDMVESIFRLGNRRVGILMIPRMDIEWLDLNHHTEELLQQINISPHNRFPVC
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHCCCCCCCCCCCC
DGELDKVIGLVTTKDVLNEILKTGKFDLKTLVKAPLFVPENMRVVQLLDLFKKTPDHIAL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEE
VTDEYGGVQGLITLHDVLESIVGDVPSTSILPETQIIQRKDGSWLVDGMLPIDELKEQFD
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEECCCCHHHHHHHCC
FDSLPEEEKGTYRTLGGFCMRQIGSIPNIGDTFTWQKFRFRVVKMNGRRVEKVLIHYLS
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MLFNNQIIIMAALIFYFVFSHSVSFTCSILEAVLLCCTNGYIGLLKKKKPKAGKILEELK
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEHCCCCCCHHHHHHHHH
HRIDRPLAAILTLNTSAHTFGAAGVGAKVVEIFGDHTLAFASIVLTLTMLIATEMIPKTF
HHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GALYWKKLAPVSAYCIQFLIWVTYPFVVSFEYIAKLLARGKTHDKITEEEIKLILEEGSQ
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
AGVIREAEHDMVESIFRLGNRRVGILMIPRMDIEWLDLNHHTEELLQQINISPHNRFPVC
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHCCCCCCCCCCCC
DGELDKVIGLVTTKDVLNEILKTGKFDLKTLVKAPLFVPENMRVVQLLDLFKKTPDHIAL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEE
VTDEYGGVQGLITLHDVLESIVGDVPSTSILPETQIIQRKDGSWLVDGMLPIDELKEQFD
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEECCCCHHHHHHHCC
FDSLPEEEKGTYRTLGGFCMRQIGSIPNIGDTFTWQKFRFRVVKMNGRRVEKVLIHYLS
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]