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The map label for this gene is comM [H]

Identifier: 46446114

GI number: 46446114

Start: 617479

End: 618996

Strand: Reverse

Name: comM [H]

Synonym: pc0480

Alternate gene names: 46446114

Gene position: 618996-617479 (Counterclockwise)

Preceding gene: 46446115

Following gene: 46446112

Centisome position: 25.64

GC content: 38.93

Gene sequence:

>1518_bases
ATGCCTTTATCCCGTATTCAATGTTTATCTTTACATGGCTTAGAAGCCATTCCTGTAGAAGTTGAGGTGGATGTCATCAA
AGCCGAAAAACTCAATTTAGTCATTGTTGGGCTTCCTGATACAGCGGTTCGTGAATCTAAAGATCGCGTGTTGACAGCAA
TTAAAAATTCGGGATTTGAAATCGGATCAATTTATTGCACTGTCAATTTAGCTCCCGGTAATTTAAAAAAAGAAGGGGCT
ATCTATGACCTTCCTATTGCGATTGGCCTCATCAATTCATTAGGACTTATAAAAAATCGCGATACACACAGGGATTATTT
AATTGTAGGAGAACTTGGATTAAGTGGACAATTACGCCCGATCACGGGTGCCTTAGCCATTGCCATGTTAGCTAGAGAAT
TAGGAAAAAAAGGAATTTTATTACCAGCAGCCAACGCCCCAGAGGCTGCTGCCGTAAGAGGAATAGCTATTTATTCTATT
GAAAATTTGAAAGAAGCGGTTCATTTTCTTCAAGATCCAAGCTCTTATAAGCCCCTTGCTTTTTCCAATCCTTTTCAACT
GTCTCGTCTCATTCCTTCTGTTGATTTTAAAGATATCAAAGGACAAGCACACGTCAAAAGAGCTTTAGAAATTGCGGCGG
CAGGAGGACATAATATTTTGCTGTCCGGTCCACCAGGATGTGGAAAAACAATGATGGCAAAAGCCTTAATTGGAATTATG
CCTGATTTGACATGGGAAGAATCTTTAGAAGTGACTCGGGTTCATTCTATTTCAGGTTTACTTAAAGAGGGCCAACATGT
CATTACAGAGCGCCCCTTTCGTTCCCCACACCATACCATCAGCTATGCTGGCTTAATAGGAGGTGGGACCTATCCACGAC
CTGGAGAAGTTTCTTTAGCTCACCAAGGAATTTTATTTCTAGATGAACTTCCTGAATTTTCACGCACTGTTCTCGAGGTA
TTAAGGCAACCTTTAGAAGATAAAAAAGTAACGATAAGTCGTGCAAGTGGAAAATTTACTTTTCCTACAAGCTTTATGTG
CGTGGCAGCCATGAATCCTTGTCCATGCGGTTATTTAGGACATCCAGATAAACCTTGCAAAGACTCGATTGCACAAATTG
AAAAATATCAAAGCAAAATTTCAGGCCCTCTTAAAGACAGAATTGATATGCATATTATCGTTCCACCCGTCAAATACCAA
GATCTTTTAGAAACAACAACGCATGAAACTTCTTGCACAATACGTTCACGAGTAATAAAAGCAAGAGAGTCTCAATCAGA
ACGTTTAGGTCAAGGAAGAACAAATTCTTCTTTAAGTACCGCAGAATTAAATAAGTACTGTTTATTAACTTCAACAAGTA
CAGTTCTTTTAAAATCTGCAATTGAAAGTTTTGGATTATCAGCCAGATCCTGTGAAAGAATTATTCGTTTAGCTCGAACC
ATTGCAGATCTGGCCTTTTCCTCTCAAATCGAGGATACGCACCTTTTGGAAGCCATTAATTTTAAAACGTCTAATTAA

Upstream 100 bases:

>100_bases
TCAAGCCATGTAGGCCAAACATTATCAACAATTAATTAAAAAAATAAGCTTAATAATAATTCTTTGATCAGATAAGATTT
ATTTTATTTTTTAAGGAAAT

Downstream 100 bases:

>100_bases
TCCATCTTAAAAAAATTCAAATTTAAAAATAAAACAATCAATTTAGTTTGCATTATTTAAATAATAAAAATTAAATAAAC
TTAATTGCATTTATAGACAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MPLSRIQCLSLHGLEAIPVEVEVDVIKAEKLNLVIVGLPDTAVRESKDRVLTAIKNSGFEIGSIYCTVNLAPGNLKKEGA
IYDLPIAIGLINSLGLIKNRDTHRDYLIVGELGLSGQLRPITGALAIAMLARELGKKGILLPAANAPEAAAVRGIAIYSI
ENLKEAVHFLQDPSSYKPLAFSNPFQLSRLIPSVDFKDIKGQAHVKRALEIAAAGGHNILLSGPPGCGKTMMAKALIGIM
PDLTWEESLEVTRVHSISGLLKEGQHVITERPFRSPHHTISYAGLIGGGTYPRPGEVSLAHQGILFLDELPEFSRTVLEV
LRQPLEDKKVTISRASGKFTFPTSFMCVAAMNPCPCGYLGHPDKPCKDSIAQIEKYQSKISGPLKDRIDMHIIVPPVKYQ
DLLETTTHETSCTIRSRVIKARESQSERLGQGRTNSSLSTAELNKYCLLTSTSTVLLKSAIESFGLSARSCERIIRLART
IADLAFSSQIEDTHLLEAINFKTSN

Sequences:

>Translated_505_residues
MPLSRIQCLSLHGLEAIPVEVEVDVIKAEKLNLVIVGLPDTAVRESKDRVLTAIKNSGFEIGSIYCTVNLAPGNLKKEGA
IYDLPIAIGLINSLGLIKNRDTHRDYLIVGELGLSGQLRPITGALAIAMLARELGKKGILLPAANAPEAAAVRGIAIYSI
ENLKEAVHFLQDPSSYKPLAFSNPFQLSRLIPSVDFKDIKGQAHVKRALEIAAAGGHNILLSGPPGCGKTMMAKALIGIM
PDLTWEESLEVTRVHSISGLLKEGQHVITERPFRSPHHTISYAGLIGGGTYPRPGEVSLAHQGILFLDELPEFSRTVLEV
LRQPLEDKKVTISRASGKFTFPTSFMCVAAMNPCPCGYLGHPDKPCKDSIAQIEKYQSKISGPLKDRIDMHIIVPPVKYQ
DLLETTTHETSCTIRSRVIKARESQSERLGQGRTNSSLSTAELNKYCLLTSTSTVLLKSAIESFGLSARSCERIIRLART
IADLAFSSQIEDTHLLEAINFKTSN
>Mature_504_residues
PLSRIQCLSLHGLEAIPVEVEVDVIKAEKLNLVIVGLPDTAVRESKDRVLTAIKNSGFEIGSIYCTVNLAPGNLKKEGAI
YDLPIAIGLINSLGLIKNRDTHRDYLIVGELGLSGQLRPITGALAIAMLARELGKKGILLPAANAPEAAAVRGIAIYSIE
NLKEAVHFLQDPSSYKPLAFSNPFQLSRLIPSVDFKDIKGQAHVKRALEIAAAGGHNILLSGPPGCGKTMMAKALIGIMP
DLTWEESLEVTRVHSISGLLKEGQHVITERPFRSPHHTISYAGLIGGGTYPRPGEVSLAHQGILFLDELPEFSRTVLEVL
RQPLEDKKVTISRASGKFTFPTSFMCVAAMNPCPCGYLGHPDKPCKDSIAQIEKYQSKISGPLKDRIDMHIIVPPVKYQD
LLETTTHETSCTIRSRVIKARESQSERLGQGRTNSSLSTAELNKYCLLTSTSTVLLKSAIESFGLSARSCERIIRLARTI
ADLAFSSQIEDTHLLEAINFKTSN

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=508, Percent_Identity=40.748031496063, Blast_Score=347, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54952; Mature: 54821

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSRIQCLSLHGLEAIPVEVEVDVIKAEKLNLVIVGLPDTAVRESKDRVLTAIKNSGFE
CCCCCEEEEEECCCEEECEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCE
IGSIYCTVNLAPGNLKKEGAIYDLPIAIGLINSLGLIKNRDTHRDYLIVGELGLSGQLRP
EEEEEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCH
ITGALAIAMLARELGKKGILLPAANAPEAAAVRGIAIYSIENLKEAVHFLQDPSSYKPLA
HHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCEEEEEEHHHHHHHHHHHCCCCCCCCCC
FSNPFQLSRLIPSVDFKDIKGQAHVKRALEIAAAGGHNILLSGPPGCGKTMMAKALIGIM
CCCCHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHC
PDLTWEESLEVTRVHSISGLLKEGQHVITERPFRSPHHTISYAGLIGGGTYPRPGEVSLA
CCCCCHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCEEEC
HQGILFLDELPEFSRTVLEVLRQPLEDKKVTISRASGKFTFPTSFMCVAAMNPCPCGYLG
CCCEEEEHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCEEEEEECCCCCCCCCC
HPDKPCKDSIAQIEKYQSKISGPLKDRIDMHIIVPPVKYQDLLETTTHETSCTIRSRVIK
CCCCCHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHH
ARESQSERLGQGRTNSSLSTAELNKYCLLTSTSTVLLKSAIESFGLSARSCERIIRLART
HHHHHHHHHCCCCCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IADLAFSSQIEDTHLLEAINFKTSN
HHHHHHHCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
PLSRIQCLSLHGLEAIPVEVEVDVIKAEKLNLVIVGLPDTAVRESKDRVLTAIKNSGFE
CCCCEEEEEECCCEEECEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCE
IGSIYCTVNLAPGNLKKEGAIYDLPIAIGLINSLGLIKNRDTHRDYLIVGELGLSGQLRP
EEEEEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCH
ITGALAIAMLARELGKKGILLPAANAPEAAAVRGIAIYSIENLKEAVHFLQDPSSYKPLA
HHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCEEEEEEHHHHHHHHHHHCCCCCCCCCC
FSNPFQLSRLIPSVDFKDIKGQAHVKRALEIAAAGGHNILLSGPPGCGKTMMAKALIGIM
CCCCHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHC
PDLTWEESLEVTRVHSISGLLKEGQHVITERPFRSPHHTISYAGLIGGGTYPRPGEVSLA
CCCCCHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCEEEC
HQGILFLDELPEFSRTVLEVLRQPLEDKKVTISRASGKFTFPTSFMCVAAMNPCPCGYLG
CCCEEEEHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCEEEEEECCCCCCCCCC
HPDKPCKDSIAQIEKYQSKISGPLKDRIDMHIIVPPVKYQDLLETTTHETSCTIRSRVIK
CCCCCHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHH
ARESQSERLGQGRTNSSLSTAELNKYCLLTSTSTVLLKSAIESFGLSARSCERIIRLART
HHHHHHHHHCCCCCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IADLAFSSQIEDTHLLEAINFKTSN
HHHHHHHCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]