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The map label for this gene is kefC [H]

Identifier: 46446015

GI number: 46446015

Start: 506404

End: 508083

Strand: Direct

Name: kefC [H]

Synonym: pc0381

Alternate gene names: 46446015

Gene position: 506404-508083 (Clockwise)

Preceding gene: 46446013

Following gene: 46446021

Centisome position: 20.97

GC content: 36.01

Gene sequence:

>1680_bases
ATGGTTAACAGCATGGACTCTCATAATCTGAAGATTGTACTCATTTTAGCCTTTGGTTTTTCTTTAGCAGGAATTTTGGG
TTATATTACTCACCGTTTAAAGCTCTCACCGATTTTGGGCTACTTACTTGCTGGATATATTATAGGTCCTTATTCCCCGG
GCTTTGTTGCAGATGTCAATGTCTCTGAACAACTAGCTGAAATTGGCGTTGTTTTAATGCTCTTTGGAGTGGGTTTACAT
CTAAAATGGGAAGATTTAGTCAACGTAAAAAATATTGCAATACCGGGTGCGATAGGACAAACTTTAGTCGCTGCCGCATG
TGGGGCTTGGATCGTTTATGCAATTGGTTGGCCTATTGAAGTGGGAATTATTGTTGGTTTGGCTATTGGCGTGGCTAGTA
CAGTTGTTCTTGTCAGAGTTTTATCTGATAATCATCTTTTAGATACGTTAGAAGGTCATGTTTCCATAGGTTGGTTAATC
GTTGAAGATATTTTGACTGTTATAGTTTTGATTTTATTACCTGTTATTTCTACCTTTGCTAAAGAAGGAAATCTTCCTTT
AATTGAATTATTAGAGACTTTAGGTTGGACAGTTTTTAAATTTCTCCTTTTAGCTCTAGTCATGTTCACATTTGGAAAAA
AAATTGTGACTTTTATTCTTATGCATATTGCTAGGCTTAGATCACATGAGCTTTTTACACTCGCTTTGTTAGCATTAACA
TTCATGATAGCAGTCGCTTCAGCACTAGTTTTTGGAACATCGATTGCATTGGGTGCATTTATCGCGGGGATGGTGATCGG
GCAAACCCACGTAAAACATCAAGCAGCAGCCAACGCTCTTCCGATGAAAGATGCATTTGCAGTTATTTTCTTTTTAACTG
TAGGGATGATTTTTAATCCCATGGCGATTATGGAGAATTTTACACTTTTTATAGGGATTTTAGCGATTGTTGTTGTTATT
AAACCACTTGCAGCATTTTTAATTGTAGTGGTCATGCGTTATCCTGTCAAAGTTGCTTTGACAGTTGCCTTGGCACTTGC
TCAAATTGGAGAGTTTTCTTTTATCTTGGGTGAAGAAGCAATTAAATTTCATCTTTTACCTGATGAAGGCTATGATATTA
TTGTTGCTTGTGCTCTTATCTCTATCTCTATCAACCCTCTCTTATTTAAAGGTATTAACTTTTTACAGAATTCTATCGAA
TCTGTGCAAAATACCTATAATCCTTTAGTTCCCAATGATATTCCTCCAGTTTTTCATTCTCTTCACGCAATTGTTATTGG
ATTTGGGCCTTTAGGTCGAGCTATTGCGCAGACTTTAGAACAGCAAAATTTTGATGTGACTGTGATTGACCAAAATGTAG
ATACAATTGCTTTCTTAAGTGATAGCCATCAACGAGCTGTTTTTGGAGATGCTACACTTCCTACCATTTTAGAAGATGCT
CATATTAAAGATGCTGATTTGCTACTGATTACTGTTCCGAATTTGAATATAACTTTAAAAATTATTCAAGTCGCACAACC
TCTCAATTCAGAAATGAAAATTTTGGCTCGAGCTAATTATTTAACAGACCAACAAAAGTTACAGAACTTAAATATTCAAT
CAGTATGTAGTGAAGAAGAAACAAAGCAAGCGTTTATCAAAATGGTCGACCGGATTGTAAAAGAAGAACTTGAGGCTTAA

Upstream 100 bases:

>100_bases
ACATTTCAATTTTAACCTAAATCAAAAAAAATTTTATGATTTAATATCCACTGTTTCTGATAAATGCTAGACGTGCTAAG
TTTCGGGAAAGCAATAATGG

Downstream 100 bases:

>100_bases
AACTAAGTTAATAAAGGCTTAATATTATTGTTACATAAATCCTTGTTGACGCCACGCTTCATACAAGGCGATACCGGCAG
AAGTAGCAAGATTTAAACAA

Product: putative glutathione-regulated potassium-efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MVNSMDSHNLKIVLILAFGFSLAGILGYITHRLKLSPILGYLLAGYIIGPYSPGFVADVNVSEQLAEIGVVLMLFGVGLH
LKWEDLVNVKNIAIPGAIGQTLVAAACGAWIVYAIGWPIEVGIIVGLAIGVASTVVLVRVLSDNHLLDTLEGHVSIGWLI
VEDILTVIVLILLPVISTFAKEGNLPLIELLETLGWTVFKFLLLALVMFTFGKKIVTFILMHIARLRSHELFTLALLALT
FMIAVASALVFGTSIALGAFIAGMVIGQTHVKHQAAANALPMKDAFAVIFFLTVGMIFNPMAIMENFTLFIGILAIVVVI
KPLAAFLIVVVMRYPVKVALTVALALAQIGEFSFILGEEAIKFHLLPDEGYDIIVACALISISINPLLFKGINFLQNSIE
SVQNTYNPLVPNDIPPVFHSLHAIVIGFGPLGRAIAQTLEQQNFDVTVIDQNVDTIAFLSDSHQRAVFGDATLPTILEDA
HIKDADLLLITVPNLNITLKIIQVAQPLNSEMKILARANYLTDQQKLQNLNIQSVCSEEETKQAFIKMVDRIVKEELEA

Sequences:

>Translated_559_residues
MVNSMDSHNLKIVLILAFGFSLAGILGYITHRLKLSPILGYLLAGYIIGPYSPGFVADVNVSEQLAEIGVVLMLFGVGLH
LKWEDLVNVKNIAIPGAIGQTLVAAACGAWIVYAIGWPIEVGIIVGLAIGVASTVVLVRVLSDNHLLDTLEGHVSIGWLI
VEDILTVIVLILLPVISTFAKEGNLPLIELLETLGWTVFKFLLLALVMFTFGKKIVTFILMHIARLRSHELFTLALLALT
FMIAVASALVFGTSIALGAFIAGMVIGQTHVKHQAAANALPMKDAFAVIFFLTVGMIFNPMAIMENFTLFIGILAIVVVI
KPLAAFLIVVVMRYPVKVALTVALALAQIGEFSFILGEEAIKFHLLPDEGYDIIVACALISISINPLLFKGINFLQNSIE
SVQNTYNPLVPNDIPPVFHSLHAIVIGFGPLGRAIAQTLEQQNFDVTVIDQNVDTIAFLSDSHQRAVFGDATLPTILEDA
HIKDADLLLITVPNLNITLKIIQVAQPLNSEMKILARANYLTDQQKLQNLNIQSVCSEEETKQAFIKMVDRIVKEELEA
>Mature_559_residues
MVNSMDSHNLKIVLILAFGFSLAGILGYITHRLKLSPILGYLLAGYIIGPYSPGFVADVNVSEQLAEIGVVLMLFGVGLH
LKWEDLVNVKNIAIPGAIGQTLVAAACGAWIVYAIGWPIEVGIIVGLAIGVASTVVLVRVLSDNHLLDTLEGHVSIGWLI
VEDILTVIVLILLPVISTFAKEGNLPLIELLETLGWTVFKFLLLALVMFTFGKKIVTFILMHIARLRSHELFTLALLALT
FMIAVASALVFGTSIALGAFIAGMVIGQTHVKHQAAANALPMKDAFAVIFFLTVGMIFNPMAIMENFTLFIGILAIVVVI
KPLAAFLIVVVMRYPVKVALTVALALAQIGEFSFILGEEAIKFHLLPDEGYDIIVACALISISINPLLFKGINFLQNSIE
SVQNTYNPLVPNDIPPVFHSLHAIVIGFGPLGRAIAQTLEQQNFDVTVIDQNVDTIAFLSDSHQRAVFGDATLPTILEDA
HIKDADLLLITVPNLNITLKIIQVAQPLNSEMKILARANYLTDQQKLQNLNIQSVCSEEETKQAFIKMVDRIVKEELEA

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=380, Percent_Identity=24.4736842105263, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1786685, Length=546, Percent_Identity=36.996336996337, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI1786232, Length=557, Percent_Identity=26.5709156193896, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789749, Length=516, Percent_Identity=25, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 60776; Mature: 60776

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNSMDSHNLKIVLILAFGFSLAGILGYITHRLKLSPILGYLLAGYIIGPYSPGFVADVN
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEECC
VSEQLAEIGVVLMLFGVGLHLKWEDLVNVKNIAIPGAIGQTLVAAACGAWIVYAIGWPIE
HHHHHHHHHHHHHHHHCCCEEEHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHCCCCHH
VGIIVGLAIGVASTVVLVRVLSDNHLLDTLEGHVSIGWLIVEDILTVIVLILLPVISTFA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
KEGNLPLIELLETLGWTVFKFLLLALVMFTFGKKIVTFILMHIARLRSHELFTLALLALT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FMIAVASALVFGTSIALGAFIAGMVIGQTHVKHQAAANALPMKDAFAVIFFLTVGMIFNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCH
MAIMENFTLFIGILAIVVVIKPLAAFLIVVVMRYPVKVALTVALALAQIGEFSFILGEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEECCCC
IKFHLLPDEGYDIIVACALISISINPLLFKGINFLQNSIESVQNTYNPLVPNDIPPVFHS
EEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LHAIVIGFGPLGRAIAQTLEQQNFDVTVIDQNVDTIAFLSDSHQRAVFGDATLPTILEDA
HHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEECCCCHHHHHHCC
HIKDADLLLITVPNLNITLKIIQVAQPLNSEMKILARANYLTDQQKLQNLNIQSVCSEEE
CCCCCCEEEEEECCCCEEEEEEEHHCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHCHHH
TKQAFIKMVDRIVKEELEA
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNSMDSHNLKIVLILAFGFSLAGILGYITHRLKLSPILGYLLAGYIIGPYSPGFVADVN
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEECC
VSEQLAEIGVVLMLFGVGLHLKWEDLVNVKNIAIPGAIGQTLVAAACGAWIVYAIGWPIE
HHHHHHHHHHHHHHHHCCCEEEHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHCCCCHH
VGIIVGLAIGVASTVVLVRVLSDNHLLDTLEGHVSIGWLIVEDILTVIVLILLPVISTFA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
KEGNLPLIELLETLGWTVFKFLLLALVMFTFGKKIVTFILMHIARLRSHELFTLALLALT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FMIAVASALVFGTSIALGAFIAGMVIGQTHVKHQAAANALPMKDAFAVIFFLTVGMIFNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCH
MAIMENFTLFIGILAIVVVIKPLAAFLIVVVMRYPVKVALTVALALAQIGEFSFILGEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEECCCC
IKFHLLPDEGYDIIVACALISISINPLLFKGINFLQNSIESVQNTYNPLVPNDIPPVFHS
EEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LHAIVIGFGPLGRAIAQTLEQQNFDVTVIDQNVDTIAFLSDSHQRAVFGDATLPTILEDA
HHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEECCCCHHHHHHCC
HIKDADLLLITVPNLNITLKIIQVAQPLNSEMKILARANYLTDQQKLQNLNIQSVCSEEE
CCCCCCEEEEEECCCCEEEEEEEHHCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHCHHH
TKQAFIKMVDRIVKEELEA
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]