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The map label for this gene is pabA [H]

Identifier: 46446001

GI number: 46446001

Start: 492937

End: 493515

Strand: Reverse

Name: pabA [H]

Synonym: pc0367

Alternate gene names: 46446001

Gene position: 493515-492937 (Counterclockwise)

Preceding gene: 46446002

Following gene: 46446000

Centisome position: 20.44

GC content: 37.65

Gene sequence:

>579_bases
GTGCTCCTTTTTATCGATAATTTTGATTCTTTTACTTATAATTTGGTCCAATACTTCCAAATGCTTGGATCTGATGTCAA
AGTATTAAGAAATCAAGGTTTATCTCTTTCTGATTGCCTCACTCTGCGCCCCACTCACTTAGTGATTGGGCCAGGGCCAG
GCACACCTTCAGAAGCCGGCATTTCTCAGCATTTAATTCGAAAAATGGCAGGCCATTTACCTATTTTAGGCATCTGTCTA
GGACACCAAGTATTGGCAGAAGCTTACGGTGGAAAAGTTGTCAAAGCCGCTTATCCTATGCATGGTAAAAGTAGTTTCAT
CTACCATGACTCGCAAGGGATTTTTAGAAACATCCCTCAATCTTTTAAAGCCATACGTTATCATTCCTTAATTGTTAAAC
ATGACAATTTACCACATTGTTTAGATATCTCAGCAACAACGAAAGAGGGGGAAATCATGGGTCTTCGACATCATTTTTAT
GATATTGAAAGCGTTCAATTTCATCCAGAATCTATCATGACAGAACATGGATTTTCTCTTTTAAGAAATTTTCTTGACAA
GCCATTATTGACGTTATAA

Upstream 100 bases:

>100_bases
TGTTCACGGTTCTGATGCTGCGGAAACAGCAAAAACAGAAATTGAATACTTTTTTAAATCTCAAGACGTTTGCGCAAGAA
AACGTTAAATCAGTATTGAT

Downstream 100 bases:

>100_bases
CCTCGAATTAAACGATTTTTAAATTTCTAATGGGGATTCAAATGAATATTTACCGCTTAATAACTTTATTTATTTTTACT
TTTGCCTTACCTGGACTATC

Product: p-aminobenzoate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLLFIDNFDSFTYNLVQYFQMLGSDVKVLRNQGLSLSDCLTLRPTHLVIGPGPGTPSEAGISQHLIRKMAGHLPILGICL
GHQVLAEAYGGKVVKAAYPMHGKSSFIYHDSQGIFRNIPQSFKAIRYHSLIVKHDNLPHCLDISATTKEGEIMGLRHHFY
DIESVQFHPESIMTEHGFSLLRNFLDKPLLTL

Sequences:

>Translated_192_residues
MLLFIDNFDSFTYNLVQYFQMLGSDVKVLRNQGLSLSDCLTLRPTHLVIGPGPGTPSEAGISQHLIRKMAGHLPILGICL
GHQVLAEAYGGKVVKAAYPMHGKSSFIYHDSQGIFRNIPQSFKAIRYHSLIVKHDNLPHCLDISATTKEGEIMGLRHHFY
DIESVQFHPESIMTEHGFSLLRNFLDKPLLTL
>Mature_192_residues
MLLFIDNFDSFTYNLVQYFQMLGSDVKVLRNQGLSLSDCLTLRPTHLVIGPGPGTPSEAGISQHLIRKMAGHLPILGICL
GHQVLAEAYGGKVVKAAYPMHGKSSFIYHDSQGIFRNIPQSFKAIRYHSLIVKHDNLPHCLDISATTKEGEIMGLRHHFY
DIESVQFHPESIMTEHGFSLLRNFLDKPLLTL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=56.6844919786096, Blast_Score=229, Evalue=7e-62,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=43.0851063829787, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=45.6989247311828, Blast_Score=188, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21541; Mature: 21541

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFIDNFDSFTYNLVQYFQMLGSDVKVLRNQGLSLSDCLTLRPTHLVIGPGPGTPSEAG
CEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHEEEECCCEEEEECCCCCCCCCH
ISQHLIRKMAGHLPILGICLGHQVLAEAYGGKVVKAAYPMHGKSSFIYHDSQGIFRNIPQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCHHHHHHH
SFKAIRYHSLIVKHDNLPHCLDISATTKEGEIMGLRHHFYDIESVQFHPESIMTEHGFSL
HHHHHHHHHEEEECCCCCCEEECCCCCCCCCEEEHHHHHCCCCCEEECHHHHHHHHHHHH
LRNFLDKPLLTL
HHHHHCCCCCCC
>Mature Secondary Structure
MLLFIDNFDSFTYNLVQYFQMLGSDVKVLRNQGLSLSDCLTLRPTHLVIGPGPGTPSEAG
CEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHEEEECCCEEEEECCCCCCCCCH
ISQHLIRKMAGHLPILGICLGHQVLAEAYGGKVVKAAYPMHGKSSFIYHDSQGIFRNIPQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCHHHHHHH
SFKAIRYHSLIVKHDNLPHCLDISATTKEGEIMGLRHHFYDIESVQFHPESIMTEHGFSL
HHHHHHHHHEEEECCCCCCEEECCCCCCCCCEEEHHHHHCCCCCEEECHHHHHHHHHHHH
LRNFLDKPLLTL
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]