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The map label for this gene is czcB [H]

Identifier: 46445923

GI number: 46445923

Start: 403381

End: 404523

Strand: Reverse

Name: czcB [H]

Synonym: pc0289

Alternate gene names: 46445923

Gene position: 404523-403381 (Counterclockwise)

Preceding gene: 46445924

Following gene: 46445922

Centisome position: 16.75

GC content: 35.87

Gene sequence:

>1143_bases
ATGAACAGAAACTCCTTCCGTTATTTTATTCTGTGTATGTTACTTTCATCAGTTCAATTATTTTCTCATTCTCAAGAAGA
GCACGAAGAAAATTCTGTTTATTTGACAACAGATCAAATCAAACAACTTGGTATCAGGATAAAAAAAGCAGGAGCTGGAA
CCCTCTTTTTATCAATTTCTACACCCGGAAAAATTATTCTTCAACCCGATCAATTAGCTCATATCGTTCCAAAAGTTTCT
GGAATTACTCGTGAGGCTAGTTATAACCTTGGTCATTTAGTCAAACGTGGAGACATAATGGCCATCTTAGAAAGTAGTGA
CATGGCAGACTATAAAGCGGCTTTTCTGGCTGCTTTAAGTCGCAAGAAATTAGCTCAATCGAGCTTAAAAAGAGAAAAAA
AGCTTTTTCAAGAAAAAATTTCTTCAGAGCAAGATTATCTCAATGCTAAGAATGGATATGAAGAATCTTTCATTAATCTT
CAGCTAGTTAAACAGAAACTGCAAGCATTTGGTTTACTTTCAAGCGAAATAGAGGAATTAGCCATCCAAAGTGAGCCTAA
CTTGAGACTCTACTCTATACGCTCTCCTATCGATGGAACAGTAATCATGAGGCATATTACAATAGGAGAATTCATAGAAA
ATACAAATATCATTTATGAAGTAGCTGATCTTTCTAAAGTATGGGTTGAAATTGGCATTTATCCTAAAGATTTGTATAAA
GTGAAAGCTGGACAATCGGTTGTCGTTACAATACCTAGTGAAAATAAATTGGCGCAAGCTAGACTCATTTATGTCAGTCC
TATTGTGGCAGATGAAACAATTGCAGCTAAAGCGATTGCAGAACTTGATAATCAAACAGGAGATTGGCGTCCGGGAGTTT
TTGTCAAAGCTTTAATCGAAACGGATCAACTGCCCTGTCCTCTCGTAGTTCCCAATGATGCGATTCAAATGATCGATGAT
CAACCAATCTTATTTGTCGGTTCTAAAAACGAATTCGAAAAGCGAATTGTTCAGCTTGGTCAAAGTGATGGAAAAAATAC
AGAAATTCTTTCTGGCTTAAAACCTGGGGAATCCTATGTTGTAAACAAAACATTTCTATTAAAAGCTGAATTAGGAAAAA
ACTCAGCTGAACATGAGGATTAG

Upstream 100 bases:

>100_bases
ACATTGTTTGAAATCACAGAAAACTATATTCAAACATTAATCAATTACCACACCAAACGTGCCGATATGGACTATTTAAA
CAGTCAACTGGATTAACTTT

Downstream 100 bases:

>100_bases
GGATGATTGAAAAAATCCTTCGCTATTCCTTATATCATCCACTTAAAGTTATCCTTTTCACTTCTTTAGTAGCTTGCTAT
GGAATTTTTTCTTTTTTTAA

Product: putative cation efflux system membrane protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNRNSFRYFILCMLLSSVQLFSHSQEEHEENSVYLTTDQIKQLGIRIKKAGAGTLFLSISTPGKIILQPDQLAHIVPKVS
GITREASYNLGHLVKRGDIMAILESSDMADYKAAFLAALSRKKLAQSSLKREKKLFQEKISSEQDYLNAKNGYEESFINL
QLVKQKLQAFGLLSSEIEELAIQSEPNLRLYSIRSPIDGTVIMRHITIGEFIENTNIIYEVADLSKVWVEIGIYPKDLYK
VKAGQSVVVTIPSENKLAQARLIYVSPIVADETIAAKAIAELDNQTGDWRPGVFVKALIETDQLPCPLVVPNDAIQMIDD
QPILFVGSKNEFEKRIVQLGQSDGKNTEILSGLKPGESYVVNKTFLLKAELGKNSAEHED

Sequences:

>Translated_380_residues
MNRNSFRYFILCMLLSSVQLFSHSQEEHEENSVYLTTDQIKQLGIRIKKAGAGTLFLSISTPGKIILQPDQLAHIVPKVS
GITREASYNLGHLVKRGDIMAILESSDMADYKAAFLAALSRKKLAQSSLKREKKLFQEKISSEQDYLNAKNGYEESFINL
QLVKQKLQAFGLLSSEIEELAIQSEPNLRLYSIRSPIDGTVIMRHITIGEFIENTNIIYEVADLSKVWVEIGIYPKDLYK
VKAGQSVVVTIPSENKLAQARLIYVSPIVADETIAAKAIAELDNQTGDWRPGVFVKALIETDQLPCPLVVPNDAIQMIDD
QPILFVGSKNEFEKRIVQLGQSDGKNTEILSGLKPGESYVVNKTFLLKAELGKNSAEHED
>Mature_380_residues
MNRNSFRYFILCMLLSSVQLFSHSQEEHEENSVYLTTDQIKQLGIRIKKAGAGTLFLSISTPGKIILQPDQLAHIVPKVS
GITREASYNLGHLVKRGDIMAILESSDMADYKAAFLAALSRKKLAQSSLKREKKLFQEKISSEQDYLNAKNGYEESFINL
QLVKQKLQAFGLLSSEIEELAIQSEPNLRLYSIRSPIDGTVIMRHITIGEFIENTNIIYEVADLSKVWVEIGIYPKDLYK
VKAGQSVVVTIPSENKLAQARLIYVSPIVADETIAAKAIAELDNQTGDWRPGVFVKALIETDQLPCPLVVPNDAIQMIDD
QPILFVGSKNEFEKRIVQLGQSDGKNTEILSGLKPGESYVVNKTFLLKAELGKNSAEHED

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=383, Percent_Identity=22.4543080939948, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786787, Length=351, Percent_Identity=21.0826210826211, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42414; Mature: 42414

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNSFRYFILCMLLSSVQLFSHSQEEHEENSVYLTTDQIKQLGIRIKKAGAGTLFLSIS
CCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEHHHHHHCCCEEEECCCCEEEEEEC
TPGKIILQPDQLAHIVPKVSGITREASYNLGHLVKRGDIMAILESSDMADYKAAFLAALS
CCCEEEECCHHHHHHHHHHCCCCHHCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHH
RKKLAQSSLKREKKLFQEKISSEQDYLNAKNGYEESFINLQLVKQKLQAFGLLSSEIEEL
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIQSEPNLRLYSIRSPIDGTVIMRHITIGEFIENTNIIYEVADLSKVWVEIGIYPKDLYK
HHCCCCCEEEEEECCCCCCEEEEEEEHHHHHHCCCCEEEEEHHHHEEEHEECCCHHHHEE
VKAGQSVVVTIPSENKLAQARLIYVSPIVADETIAAKAIAELDNQTGDWRPGVFVKALIE
EECCCEEEEEECCCCCCEEEEEEEEECEECCHHHHHHHHHHHCCCCCCCCCCHHHEEEEC
TDQLPCPLVVPNDAIQMIDDQPILFVGSKNEFEKRIVQLGQSDGKNTEILSGLKPGESYV
CCCCCCCEECCCCHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCEE
VNKTFLLKAELGKNSAEHED
EEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNRNSFRYFILCMLLSSVQLFSHSQEEHEENSVYLTTDQIKQLGIRIKKAGAGTLFLSIS
CCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEHHHHHHCCCEEEECCCCEEEEEEC
TPGKIILQPDQLAHIVPKVSGITREASYNLGHLVKRGDIMAILESSDMADYKAAFLAALS
CCCEEEECCHHHHHHHHHHCCCCHHCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHH
RKKLAQSSLKREKKLFQEKISSEQDYLNAKNGYEESFINLQLVKQKLQAFGLLSSEIEEL
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIQSEPNLRLYSIRSPIDGTVIMRHITIGEFIENTNIIYEVADLSKVWVEIGIYPKDLYK
HHCCCCCEEEEEECCCCCCEEEEEEEHHHHHHCCCCEEEEEHHHHEEEHEECCCHHHHEE
VKAGQSVVVTIPSENKLAQARLIYVSPIVADETIAAKAIAELDNQTGDWRPGVFVKALIE
EECCCEEEEEECCCCCCEEEEEEEEECEECCHHHHHHHHHHHCCCCCCCCCCHHHEEEEC
TDQLPCPLVVPNDAIQMIDDQPILFVGSKNEFEKRIVQLGQSDGKNTEILSGLKPGESYV
CCCCCCCEECCCCHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCEE
VNKTFLLKAELGKNSAEHED
EEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]