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The map label for this gene is czcC [H]

Identifier: 46445924

GI number: 46445924

Start: 404528

End: 405682

Strand: Reverse

Name: czcC [H]

Synonym: pc0290

Alternate gene names: 46445924

Gene position: 405682-404528 (Counterclockwise)

Preceding gene: 46445926

Following gene: 46445923

Centisome position: 16.8

GC content: 36.45

Gene sequence:

>1155_bases
TTGAATCAGGCCGTATATCGCGTTTTAACCGCTTCACCTTCTCTACAAATTGCCAAAAAAGAATCCTCTGCTAAATACTC
TTCAGTTAAACAAGCCCAGCTCGCTCCTAGTCCCGTTCTGAGCTATGAAGTCGAAAACTTCTCTGGTCGACGCACCTGGA
AAGGTTGGAATCATCGAGAAGAGAGCTATATTTGGTCTCAATTATTTGAAACTGGGGATAAACGGCAAATACGAACGCAA
GCTGCATCTTATCGCTATTACGCAGCTATGGTGGGTTATGATATTTCAAAACTTGTCCTGCTAAACCGTCTTCATCGCGC
TTTCATACAAGTAGCTGCCAACCAGGAACTTTTAAAAAACGCAATTCAACAATCACAAATTGCTAAAGAAATGCTAGACA
TTGCCACAAAAAAAGTGGAGGCTGGTAAAGTTTCTTTAATCCAACAAAATAAAGCACAAGTGGCTTATTCTCTAACATTA
ATTAACTCTGAAAAAGCTCAAATAGATTTAAAAAATGCCAAACGAAGATTATCTTTGCTTTGGGCTGAAACGTGTCCTGA
CTTTAAAACCGTCTTATTTCCCTTTTTTGACCTCGAAATGCCGAAAGAACTTCAAACTTACATTGAAGATCTTTGCAATC
AACCAGAAATTACTCAACTGCTCTATCAATTTCAAAATGCAAAACATCATTGGCGATTGGAAAAAGCGAATCGTATTCCT
GATGTGACTATGCAAGTAGGATATAAAATCAATTATGAAGAAAAAAATCAGGGATTAATTGCCGGAGTATCCATCCCTAT
TCCCATTTTTAACCAAAATCAAGGCAACATCTCAGAAGCCTATTTTGAAATGTTAAAAGTTGATGAACAGAAAAGATTGC
TAGCCCTTACTCTCCAGTCTAAATTGTCTATTATTCATGAAGAATTTAATCGCTCTTACTTAGAAGCCCAAGAAATACAA
AGCAAAACTCTTCCTTTAGCGAAACAAGCTTTTGAACTAGCGCATAAAGGATATTTAGAAGGAAAATTCGAATATTTGGA
CGTATTAGATGCTCAAAGAACATTGTTTGAAATCACAGAAAACTATATTCAAACATTAATCAATTACCACACCAAACGTG
CCGATATGGACTATTTAAACAGTCAACTGGATTAA

Upstream 100 bases:

>100_bases
TTTTATATTCTTCGTGTTGAAAACTTTTGGATTTCCTACTCTTTCATTTTTACACGCCGAAGTAGATGAAAATAGGGAAA
GCAATCTCCCCATTTTAGAC

Downstream 100 bases:

>100_bases
CTTTATGAACAGAAACTCCTTCCGTTATTTTATTCTGTGTATGTTACTTTCATCAGTTCAATTATTTTCTCATTCTCAAG
AAGAGCACGAAGAAAATTCT

Product: putative cation efflux system membrane protein C

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNQAVYRVLTASPSLQIAKKESSAKYSSVKQAQLAPSPVLSYEVENFSGRRTWKGWNHREESYIWSQLFETGDKRQIRTQ
AASYRYYAAMVGYDISKLVLLNRLHRAFIQVAANQELLKNAIQQSQIAKEMLDIATKKVEAGKVSLIQQNKAQVAYSLTL
INSEKAQIDLKNAKRRLSLLWAETCPDFKTVLFPFFDLEMPKELQTYIEDLCNQPEITQLLYQFQNAKHHWRLEKANRIP
DVTMQVGYKINYEEKNQGLIAGVSIPIPIFNQNQGNISEAYFEMLKVDEQKRLLALTLQSKLSIIHEEFNRSYLEAQEIQ
SKTLPLAKQAFELAHKGYLEGKFEYLDVLDAQRTLFEITENYIQTLINYHTKRADMDYLNSQLD

Sequences:

>Translated_384_residues
MNQAVYRVLTASPSLQIAKKESSAKYSSVKQAQLAPSPVLSYEVENFSGRRTWKGWNHREESYIWSQLFETGDKRQIRTQ
AASYRYYAAMVGYDISKLVLLNRLHRAFIQVAANQELLKNAIQQSQIAKEMLDIATKKVEAGKVSLIQQNKAQVAYSLTL
INSEKAQIDLKNAKRRLSLLWAETCPDFKTVLFPFFDLEMPKELQTYIEDLCNQPEITQLLYQFQNAKHHWRLEKANRIP
DVTMQVGYKINYEEKNQGLIAGVSIPIPIFNQNQGNISEAYFEMLKVDEQKRLLALTLQSKLSIIHEEFNRSYLEAQEIQ
SKTLPLAKQAFELAHKGYLEGKFEYLDVLDAQRTLFEITENYIQTLINYHTKRADMDYLNSQLD
>Mature_384_residues
MNQAVYRVLTASPSLQIAKKESSAKYSSVKQAQLAPSPVLSYEVENFSGRRTWKGWNHREESYIWSQLFETGDKRQIRTQ
AASYRYYAAMVGYDISKLVLLNRLHRAFIQVAANQELLKNAIQQSQIAKEMLDIATKKVEAGKVSLIQQNKAQVAYSLTL
INSEKAQIDLKNAKRRLSLLWAETCPDFKTVLFPFFDLEMPKELQTYIEDLCNQPEITQLLYQFQNAKHHWRLEKANRIP
DVTMQVGYKINYEEKNQGLIAGVSIPIPIFNQNQGNISEAYFEMLKVDEQKRLLALTLQSKLSIIHEEFNRSYLEAQEIQ
SKTLPLAKQAFELAHKGYLEGKFEYLDVLDAQRTLFEITENYIQTLINYHTKRADMDYLNSQLD

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 44511; Mature: 44511

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAVYRVLTASPSLQIAKKESSAKYSSVKQAQLAPSPVLSYEVENFSGRRTWKGWNHRE
CCHHHEEHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCH
ESYIWSQLFETGDKRQIRTQAASYRYYAAMVGYDISKLVLLNRLHRAFIQVAANQELLKN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AIQQSQIAKEMLDIATKKVEAGKVSLIQQNKAQVAYSLTLINSEKAQIDLKNAKRRLSLL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHH
WAETCPDFKTVLFPFFDLEMPKELQTYIEDLCNQPEITQLLYQFQNAKHHWRLEKANRIP
HHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHEEEHHHCCCC
DVTMQVGYKINYEEKNQGLIAGVSIPIPIFNQNQGNISEAYFEMLKVDEQKRLLALTLQS
CCEEEECEEECCCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
KLSIIHEEFNRSYLEAQEIQSKTLPLAKQAFELAHKGYLEGKFEYLDVLDAQRTLFEITE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
NYIQTLINYHTKRADMDYLNSQLD
HHHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MNQAVYRVLTASPSLQIAKKESSAKYSSVKQAQLAPSPVLSYEVENFSGRRTWKGWNHRE
CCHHHEEHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCH
ESYIWSQLFETGDKRQIRTQAASYRYYAAMVGYDISKLVLLNRLHRAFIQVAANQELLKN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AIQQSQIAKEMLDIATKKVEAGKVSLIQQNKAQVAYSLTLINSEKAQIDLKNAKRRLSLL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHH
WAETCPDFKTVLFPFFDLEMPKELQTYIEDLCNQPEITQLLYQFQNAKHHWRLEKANRIP
HHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHEEEHHHCCCC
DVTMQVGYKINYEEKNQGLIAGVSIPIPIFNQNQGNISEAYFEMLKVDEQKRLLALTLQS
CCEEEECEEECCCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
KLSIIHEEFNRSYLEAQEIQSKTLPLAKQAFELAHKGYLEGKFEYLDVLDAQRTLFEITE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
NYIQTLINYHTKRADMDYLNSQLD
HHHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]