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The map label for this gene is ynaI [H]

Identifier: 46445877

GI number: 46445877

Start: 341231

End: 342376

Strand: Reverse

Name: ynaI [H]

Synonym: pc0243

Alternate gene names: 46445877

Gene position: 342376-341231 (Counterclockwise)

Preceding gene: 46445878

Following gene: 46445876

Centisome position: 14.18

GC content: 34.38

Gene sequence:

>1146_bases
ATGGATATGACTGCACATGCTTTTTCTTTTTTTCAAGTGTCTTCTCAAGTCTTAGAAGGCTCCTATGGACTATTTTTACA
GATCTTAAGTATTGTTCTTTTTTTACTATTTTTTAATTTTCTTATTAAAGTTGGTTTAACTAAATTAAAAAAACGTTTTT
TAAGTCAAAATAAAATTTGGTCTTCTAGTTTTGTTTCAGCGATAGAAAAACCCCTTAATTATTATGCTTGGTTTGTTGCT
TGTATTTGCGCTCTTGACGCAGCAATCAATCGATTTTTAGAACATCATCTTTTTAATGTACATGTCATTCTAAATCTAGG
GGCAGTTTTAGCCATCGGTTGGTTTCTCTTAAGATGGAATAATAAAGTTTTACAAGACATGCTGAGTATGAGCTACCAGC
ACCGCATTAATCTTACTCCTGCTAAATTAGATTTGATTAGTAAGCTAGCGACTATTGTTATTATTTTTTTAACAGTTTTT
CTAGCCATGGATGTTACGGGTCGCGACATGCAAACGGTGATTGCATTTGGAGGAATTGGTGGTTTAGCCATTGCTTTTGC
GTCGCAACAAGCCATTGCAAATTTTTTTGGCGGAGTCATGGTCTATCTCACACAACCTTTTAGCATCGGAGAACTCATTA
ATATTCCTGAAAAAAAAATTGAAGGACATGTGGAAGAAATTGGTTGGTACATGACACGTATTCGGAATCTAGACAAACGA
CCTATTTATGTTCCCAATTCAGTTTTTACACAAACGATTGTCATTACTCCTTCTCGAATGAGTCATGAACGTTTTTTTCA
TACAATTGGATTGCGCTATAGTGATATCGATTCTATTAAACAAATAGTTGCTGATATCAAATTAATGCTTCTTAAGCATC
CACAGGTAGATCATGAACAAAGAGTAGATGTTTATTTTGTAAGCTTTGGAGATTTTGCTTTAAATATTAGTATTTCTGCT
TATATTCATTTAGGCCAGGCAGATTTCCCCAGTATTCGGCAGGATATTTTATTAAAAATTGCCGACCTTATTCGAAGTCA
CGGAGCCTCTATTGCTATCTCTCCACAAACTATTCAGATAGCATCCGGAATGCAATTGATTCCTAATGTGGAACCATCAA
AACCATCATTATCCACTTCTTCTTAA

Upstream 100 bases:

>100_bases
GGTCAACCGCTCATGATCAAGGATTAAAAATTCTTTTAATTAATGCTGGATGAATGAGATTTAATTCAGCATTGATTTAT
GCAAGTATAGGAGAGATAAA

Downstream 100 bases:

>100_bases
TCAACACGTACAACAAGTGAGAACTTTAGTAGTAGTAGCTATAAACAGCCAAAAAAGTTACAATTAGTCTTATATATACT
CAACCACTTAATTTTTTTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDMTAHAFSFFQVSSQVLEGSYGLFLQILSIVLFLLFFNFLIKVGLTKLKKRFLSQNKIWSSSFVSAIEKPLNYYAWFVA
CICALDAAINRFLEHHLFNVHVILNLGAVLAIGWFLLRWNNKVLQDMLSMSYQHRINLTPAKLDLISKLATIVIIFLTVF
LAMDVTGRDMQTVIAFGGIGGLAIAFASQQAIANFFGGVMVYLTQPFSIGELINIPEKKIEGHVEEIGWYMTRIRNLDKR
PIYVPNSVFTQTIVITPSRMSHERFFHTIGLRYSDIDSIKQIVADIKLMLLKHPQVDHEQRVDVYFVSFGDFALNISISA
YIHLGQADFPSIRQDILLKIADLIRSHGASIAISPQTIQIASGMQLIPNVEPSKPSLSTSS

Sequences:

>Translated_381_residues
MDMTAHAFSFFQVSSQVLEGSYGLFLQILSIVLFLLFFNFLIKVGLTKLKKRFLSQNKIWSSSFVSAIEKPLNYYAWFVA
CICALDAAINRFLEHHLFNVHVILNLGAVLAIGWFLLRWNNKVLQDMLSMSYQHRINLTPAKLDLISKLATIVIIFLTVF
LAMDVTGRDMQTVIAFGGIGGLAIAFASQQAIANFFGGVMVYLTQPFSIGELINIPEKKIEGHVEEIGWYMTRIRNLDKR
PIYVPNSVFTQTIVITPSRMSHERFFHTIGLRYSDIDSIKQIVADIKLMLLKHPQVDHEQRVDVYFVSFGDFALNISISA
YIHLGQADFPSIRQDILLKIADLIRSHGASIAISPQTIQIASGMQLIPNVEPSKPSLSTSS
>Mature_381_residues
MDMTAHAFSFFQVSSQVLEGSYGLFLQILSIVLFLLFFNFLIKVGLTKLKKRFLSQNKIWSSSFVSAIEKPLNYYAWFVA
CICALDAAINRFLEHHLFNVHVILNLGAVLAIGWFLLRWNNKVLQDMLSMSYQHRINLTPAKLDLISKLATIVIIFLTVF
LAMDVTGRDMQTVIAFGGIGGLAIAFASQQAIANFFGGVMVYLTQPFSIGELINIPEKKIEGHVEEIGWYMTRIRNLDKR
PIYVPNSVFTQTIVITPSRMSHERFFHTIGLRYSDIDSIKQIVADIKLMLLKHPQVDHEQRVDVYFVSFGDFALNISISA
YIHLGQADFPSIRQDILLKIADLIRSHGASIAISPQTIQIASGMQLIPNVEPSKPSLSTSS

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=223, Percent_Identity=41.2556053811659, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1789291, Length=245, Percent_Identity=27.3469387755102, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786670, Length=217, Percent_Identity=25.3456221198157, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 42906; Mature: 42906

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]