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The map label for this gene is pdxS

Identifier: 46445871

GI number: 46445871

Start: 333724

End: 334623

Strand: Direct

Name: pdxS

Synonym: pc0237

Alternate gene names: 46445871

Gene position: 333724-334623 (Clockwise)

Preceding gene: 46445870

Following gene: 46445872

Centisome position: 13.82

GC content: 41.22

Gene sequence:

>900_bases
ATGGGACAATTTAATCAAACTGAAAAAGGATCATTTGAAATTAAAGTTGCCTTGGCAGAGATGTTGAAAGGAGGAGTGAT
CATGGATGTCACGAACTCAGAGCAAGCTAAAATTGCAGAGGATGCTGGGGCGGTTGCCGTTATGGCTTTAGAAAGAATTC
CGTCTGATATTCGTGTTCAGGGCGGAATCGCCCGCATGTCAAATCCTGAACTTATCCAGAAAATTCAAGAAACAGTTTCG
ATACCTGTTATGGCTAAATGTCGAATTGGACATTTTGTAGAAGCACAAATTTTAGAGTCATTACAAGTTGATTTTATTGA
TGAAAGCGAAGTTTTAACGCCTGCTGATGAAGAAAACCATATCGATAAACATATTTTTAAAGTTCCCTTTGTTTGTGGTT
GTCGAGATTTAGGGGAAGCTTTAAGAAGAATTGGTGAAGGGGCTGCAATGATTCGAACGAAAGGGGAAGCCGGCACAGGA
AATGTTGTCGAAGCTGTTCGACATATGCGGGCCATTAATCGAGAAATCAGGCATTTAATGCTGATGGATTCTTCGGAACT
CATGGCAGAAGCTAAACGATTAGGTGCCCCCTTTCATTTAGTCCAAATGGTTGCAAAATCTGGTGTGCTCCCTGTGCCTA
ATTTCGCTGCAGGTGGAATTGCCACTCCAGCAGATGCTGCTTTGATGATGCAATTAGGGGCACAATCTGTTTTTGTAGGA
TCGGGAATTTTTAAATCAGAAGATCCTGCAAAAAGAGCTCGTGCAATAGTCGGGGCCACCACATTTTTTCAAAATCCTGA
AAAATTAGCTCAATTTTCGATGGATCTTCTTGATGCGATGAAAGGGATTGATATTAGACAACTTAAACGAGAAGATTTGA
TGGCTCAAAGAGGTTGGTAG

Upstream 100 bases:

>100_bases
GCTTTTTTCTGTACGAACCGAGTTAAAAAGACGTAAACATGGAAATCAGTTTAATCAATCCAGTAATCCTTTCTTAAAAC
TTTAATGCATAGGGGTAGAC

Downstream 100 bases:

>100_bases
AGCATGCTGATAGGTATATTAGCATTACAGGGAGATTTCTTTAAACATCAAGAAATGCTTCATTCTCTTGGTATAGAAAC
GATCCAAGTTAAAACTCGAA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGQFNQTEKGSFEIKVALAEMLKGGVIMDVTNSEQAKIAEDAGAVAVMALERIPSDIRVQGGIARMSNPELIQKIQETVS
IPVMAKCRIGHFVEAQILESLQVDFIDESEVLTPADEENHIDKHIFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTG
NVVEAVRHMRAINREIRHLMLMDSSELMAEAKRLGAPFHLVQMVAKSGVLPVPNFAAGGIATPADAALMMQLGAQSVFVG
SGIFKSEDPAKRARAIVGATTFFQNPEKLAQFSMDLLDAMKGIDIRQLKREDLMAQRGW

Sequences:

>Translated_299_residues
MGQFNQTEKGSFEIKVALAEMLKGGVIMDVTNSEQAKIAEDAGAVAVMALERIPSDIRVQGGIARMSNPELIQKIQETVS
IPVMAKCRIGHFVEAQILESLQVDFIDESEVLTPADEENHIDKHIFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTG
NVVEAVRHMRAINREIRHLMLMDSSELMAEAKRLGAPFHLVQMVAKSGVLPVPNFAAGGIATPADAALMMQLGAQSVFVG
SGIFKSEDPAKRARAIVGATTFFQNPEKLAQFSMDLLDAMKGIDIRQLKREDLMAQRGW
>Mature_298_residues
GQFNQTEKGSFEIKVALAEMLKGGVIMDVTNSEQAKIAEDAGAVAVMALERIPSDIRVQGGIARMSNPELIQKIQETVSI
PVMAKCRIGHFVEAQILESLQVDFIDESEVLTPADEENHIDKHIFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTGN
VVEAVRHMRAINREIRHLMLMDSSELMAEAKRLGAPFHLVQMVAKSGVLPVPNFAAGGIATPADAALMMQLGAQSVFVGS
GIFKSEDPAKRARAIVGATTFFQNPEKLAQFSMDLLDAMKGIDIRQLKREDLMAQRGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321049, Length=295, Percent_Identity=63.0508474576271, Blast_Score=357, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6323996, Length=295, Percent_Identity=63.0508474576271, Blast_Score=357, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6323743, Length=292, Percent_Identity=60.2739726027397, Blast_Score=345, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_PARUW (Q6MEN8)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007236.1
- ProteinModelPortal:   Q6MEN8
- SMR:   Q6MEN8
- STRING:   Q6MEN8
- GeneID:   2780617
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0237
- NMPDR:   fig|264201.1.peg.237
- eggNOG:   COG0214
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- PhylomeDB:   Q6MEN8
- ProtClustDB:   PRK04180
- BioCyc:   CPRO264201:PC0237-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 32557; Mature: 32426

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQFNQTEKGSFEIKVALAEMLKGGVIMDVTNSEQAKIAEDAGAVAVMALERIPSDIRVQ
CCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCHHHHHHHCCHHHHHHHHHCCCCEEEC
GGIARMSNPELIQKIQETVSIPVMAKCRIGHFVEAQILESLQVDFIDESEVLTPADEENH
CCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
IDKHIFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTGNVVEAVRHMRAINREIRHLM
HHHHHHHCCHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LMDSSELMAEAKRLGAPFHLVQMVAKSGVLPVPNFAAGGIATPADAALMMQLGAQSVFVG
HCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEC
SGIFKSEDPAKRARAIVGATTFFQNPEKLAQFSMDLLDAMKGIDIRQLKREDLMAQRGW
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GQFNQTEKGSFEIKVALAEMLKGGVIMDVTNSEQAKIAEDAGAVAVMALERIPSDIRVQ
CCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCHHHHHHHCCHHHHHHHHHCCCCEEEC
GGIARMSNPELIQKIQETVSIPVMAKCRIGHFVEAQILESLQVDFIDESEVLTPADEENH
CCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
IDKHIFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTGNVVEAVRHMRAINREIRHLM
HHHHHHHCCHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LMDSSELMAEAKRLGAPFHLVQMVAKSGVLPVPNFAAGGIATPADAALMMQLGAQSVFVG
HCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEC
SGIFKSEDPAKRARAIVGATTFFQNPEKLAQFSMDLLDAMKGIDIRQLKREDLMAQRGW
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA