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The map label for this gene is ywlC [H]

Identifier: 46445827

GI number: 46445827

Start: 287256

End: 288191

Strand: Direct

Name: ywlC [H]

Synonym: pc0193

Alternate gene names: 46445827

Gene position: 287256-288191 (Clockwise)

Preceding gene: 46445826

Following gene: 46445832

Centisome position: 11.9

GC content: 41.67

Gene sequence:

>936_bases
ATGCGTATTAATGTGGAAGAAGCGATTGAGAAATTGTTAGCGAATCAATTAGTCGCAATGCCGACAGAAACAGTTTATGG
GTTAGCAGCTAGGCTGACTTGCCCTGGAGCAATCAAAAAAATTTTCGAGATAAAAGGACGCTCTCTAGTAAATCCTTTGA
TCATTCATGTTGCCAATCCTATAGATGTGTGTGCGTATGCGATCGCTCTACCTCCCCATTTTGACGCGTTAACCCATGCC
TTTTGGCCGGGTCCGCTCACGCTCATTGTTCCAATTCAATTAGATTTAGTAGATTCCATTGTCAGAGCAGGGCTTCCAAC
AGCAGCTTTTAGAATGCCTTCTCATCCTTTAACTTTGCATGTCATCCGAGCTGTTGGTCCTTTGGTCATGCCTTCTGCAA
ATTTATCAGGAAAGCCCTCTTCTACCGATGTAAAACATGTAGAAATGGATTTTGGCTTAGATTTTCCCGTCTTAGATGGA
GGGCCCTGTCAAGAAGGTGTTGAATCGACAATTTTACATTATCGAAATTCTCAGTGGGAAATAGCACGTCTAGGAGCCTT
ATCAGCTACTGTTTTTCAACCTATTTTAGGTTATGAGCCCATCTATCAAAAAATAGTTAAAAACGATCAAATTATTTCTC
CGGGACAAATGTTCCGTCATTATGCTCCTCAAGCAACCCTATTTTTAGGGGACCAAAAACAGATAACAGAAGCTGATTTT
ATTGTGGGATTTACAGAAAAATCCTACCCTGTTGAAAAGCGAGTTTTATATCTAGGTTCGCTCTCCAACCCTCATGAGGT
TGCAGAAAACCTCTATGCCGTCTTACGTCAGCTCGATTTCGAGAAAGCAAAAATTGCTTGGGTAGACATGGACTTTCCTT
CAGAAGGGCTTTGGAAAACCATTGCCGAGCGTTTATCTAGAGCAGGAGAAAAGTAA

Upstream 100 bases:

>100_bases
CCACAGCACGGGTATCTTTTGCTTTTTATAATACGGCTGATGAAATTGACCGGCTACATTTAGCTTTAAGTGATATTATT
AAGCGGTTAAAATAAAATTT

Downstream 100 bases:

>100_bases
TTGAGCCTTCTTTCCATATTTTTAAATTAGTTTTCAAGATTAAAGAAAAATTCTTTTTATACCTCTAATTCGCAAGCCAC
TAAAGAAAAAATAATTTCTC

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRINVEEAIEKLLANQLVAMPTETVYGLAARLTCPGAIKKIFEIKGRSLVNPLIIHVANPIDVCAYAIALPPHFDALTHA
FWPGPLTLIVPIQLDLVDSIVRAGLPTAAFRMPSHPLTLHVIRAVGPLVMPSANLSGKPSSTDVKHVEMDFGLDFPVLDG
GPCQEGVESTILHYRNSQWEIARLGALSATVFQPILGYEPIYQKIVKNDQIISPGQMFRHYAPQATLFLGDQKQITEADF
IVGFTEKSYPVEKRVLYLGSLSNPHEVAENLYAVLRQLDFEKAKIAWVDMDFPSEGLWKTIAERLSRAGEK

Sequences:

>Translated_311_residues
MRINVEEAIEKLLANQLVAMPTETVYGLAARLTCPGAIKKIFEIKGRSLVNPLIIHVANPIDVCAYAIALPPHFDALTHA
FWPGPLTLIVPIQLDLVDSIVRAGLPTAAFRMPSHPLTLHVIRAVGPLVMPSANLSGKPSSTDVKHVEMDFGLDFPVLDG
GPCQEGVESTILHYRNSQWEIARLGALSATVFQPILGYEPIYQKIVKNDQIISPGQMFRHYAPQATLFLGDQKQITEADF
IVGFTEKSYPVEKRVLYLGSLSNPHEVAENLYAVLRQLDFEKAKIAWVDMDFPSEGLWKTIAERLSRAGEK
>Mature_311_residues
MRINVEEAIEKLLANQLVAMPTETVYGLAARLTCPGAIKKIFEIKGRSLVNPLIIHVANPIDVCAYAIALPPHFDALTHA
FWPGPLTLIVPIQLDLVDSIVRAGLPTAAFRMPSHPLTLHVIRAVGPLVMPSANLSGKPSSTDVKHVEMDFGLDFPVLDG
GPCQEGVESTILHYRNSQWEIARLGALSATVFQPILGYEPIYQKIVKNDQIISPGQMFRHYAPQATLFLGDQKQITEADF
IVGFTEKSYPVEKRVLYLGSLSNPHEVAENLYAVLRQLDFEKAKIAWVDMDFPSEGLWKTIAERLSRAGEK

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=163, Percent_Identity=31.2883435582822, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI2367210, Length=169, Percent_Identity=32.5443786982249, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=326, Percent_Identity=30.6748466257669, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI78707274, Length=139, Percent_Identity=33.8129496402878, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34416; Mature: 34416

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINVEEAIEKLLANQLVAMPTETVYGLAARLTCPGAIKKIFEIKGRSLVNPLIIHVANP
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHCHHHEEECCH
IDVCAYAIALPPHFDALTHAFWPGPLTLIVPIQLDLVDSIVRAGLPTAAFRMPSHPLTLH
HHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCHHHHCCCCCCHHHH
VIRAVGPLVMPSANLSGKPSSTDVKHVEMDFGLDFPVLDGGPCQEGVESTILHYRNSQWE
HHHHHCCCEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
IARLGALSATVFQPILGYEPIYQKIVKNDQIISPGQMFRHYAPQATLFLGDQKQITEADF
EHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCHHCCCCCE
IVGFTEKSYPVEKRVLYLGSLSNPHEVAENLYAVLRQLDFEKAKIAWVDMDFPSEGLWKT
EEEECCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
IAERLSRAGEK
HHHHHHHCCCC
>Mature Secondary Structure
MRINVEEAIEKLLANQLVAMPTETVYGLAARLTCPGAIKKIFEIKGRSLVNPLIIHVANP
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHCHHHEEECCH
IDVCAYAIALPPHFDALTHAFWPGPLTLIVPIQLDLVDSIVRAGLPTAAFRMPSHPLTLH
HHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCHHHHCCCCCCHHHH
VIRAVGPLVMPSANLSGKPSSTDVKHVEMDFGLDFPVLDGGPCQEGVESTILHYRNSQWE
HHHHHCCCEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
IARLGALSATVFQPILGYEPIYQKIVKNDQIISPGQMFRHYAPQATLFLGDQKQITEADF
EHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCHHCCCCCE
IVGFTEKSYPVEKRVLYLGSLSNPHEVAENLYAVLRQLDFEKAKIAWVDMDFPSEGLWKT
EEEECCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
IAERLSRAGEK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]