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The map label for this gene is wzt [H]

Identifier: 46445815

GI number: 46445815

Start: 271746

End: 273002

Strand: Reverse

Name: wzt [H]

Synonym: pc0181

Alternate gene names: 46445815

Gene position: 273002-271746 (Counterclockwise)

Preceding gene: 46445816

Following gene: 46445814

Centisome position: 11.31

GC content: 35.32

Gene sequence:

>1257_bases
ATGAATATCGTTGAAATCGAGCAGTTATCTAAAAAATATTTAATTTCTCATGAAAATCAAAATCCTTACGCTTCTTTAAA
AGAAATTGCTACTGATTGGTTTAAAAATTCTTTTAAACGTTTAACTTCCCCTTCAACTTCTTTTGTGGAACAGTGTGAAG
AGTTTTGGGCAGTCCAAGATATCAATTTAAATATTCAGCAAGGAGATCGAATTGCTCTGCTAGGGCGGAATGGAGCGGGT
AAATCAACATTACTAAAACTAATTTCGCGCATTACAGAACCTACAACAGGCAAAATCAAAATCCGAGGGCGTGTTTCGTG
CTTGTTAGAAGTGGGAACAGGGTTTCATCCTGATTTAACAGGTCGAGAAAATATTTTTCTGAACGGCGCAATTATGGGAA
TGAGTTATCAAGAAATACAAACTAAATTTGATGAAATTGTTGATTTTGCCGAAATAGAAAAATTCTTAGATACACCAATC
AAAAAATACTCTAGTGGTATGTATATGCGGCTTGGATTTGCTATTGCCGCCCACTTAAATTCTGATCTTCTAATTGTCGA
TGAAGTTTTAGCTGTAGGAGATGCACAATTTCAAGAAAAATGCATAAAAAAAATGAATGAAATGGGAATGCAAGGAAGTA
CTGTTTTATTTGTGAGTCACAGTGTGAGTTCTGTGCTTTCTCTATGCAATAAAGGAGCCTTTCTCGAAAAAGGAAGACTG
AAAGCTCTGGAGCCAATTGAAACCTGCGTTAACCGCTATATCAACAGTTGTCCCGCTGCAGGACTTGAGTGGAAAGGAAC
CTTGGGAGATGAGCATGTTCAATTTTTTCAAACAAAATTATCCACTCCTAAATCTAGTTCGGCCCTTTTTTACCACGATG
AACAAGCAATTATCAGCATCGATTTTGAAATTTTGAAAACTCAACCCGACCTTATTTTAGGAATTAGTATTTTAAATAGT
CGCAATCAAATTATTGCAAGATCTCGCCTTTGCGATCATGATGAATATTACGATCTCATTTCAAAAATGGGGCGCCATCA
TTTAAACTACGCTTTAGATCCCAGCCTATTCCATCCTGGCGAATATCAAATCCGATTAGAATGTTCTATTTTAAACAAAA
AGAAAATCCTACAAGGTGAAATTTTATTGAAATTTATTGTTTATTCTTCACAAATCCAACAATCCAAATATGAATTTGGA
ACTGACAAAGATGGAATTAGCTTAGGAAATCGTTGGTTCCTGTCAAAGCACTTATAA

Upstream 100 bases:

>100_bases
TTGCTTTTATCTAGTCTGATAAACTTCATTTTGTTAATCACCGGATTTAGATATTTCCGTAAAATGGAACGTATTTTTGC
AGACATTATTTGAGTAAACT

Downstream 100 bases:

>100_bases
AGCCATGACTCAAGGAAGTGATCGTTTTCAATTTTTGGATGGACTCAGAGGAATAGCAGCTTTATGGGTCGTTCTCCTTC
ATTTTCATACGCTCATTAAT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNIVEIEQLSKKYLISHENQNPYASLKEIATDWFKNSFKRLTSPSTSFVEQCEEFWAVQDINLNIQQGDRIALLGRNGAG
KSTLLKLISRITEPTTGKIKIRGRVSCLLEVGTGFHPDLTGRENIFLNGAIMGMSYQEIQTKFDEIVDFAEIEKFLDTPI
KKYSSGMYMRLGFAIAAHLNSDLLIVDEVLAVGDAQFQEKCIKKMNEMGMQGSTVLFVSHSVSSVLSLCNKGAFLEKGRL
KALEPIETCVNRYINSCPAAGLEWKGTLGDEHVQFFQTKLSTPKSSSALFYHDEQAIISIDFEILKTQPDLILGISILNS
RNQIIARSRLCDHDEYYDLISKMGRHHLNYALDPSLFHPGEYQIRLECSILNKKKILQGEILLKFIVYSSQIQQSKYEFG
TDKDGISLGNRWFLSKHL

Sequences:

>Translated_418_residues
MNIVEIEQLSKKYLISHENQNPYASLKEIATDWFKNSFKRLTSPSTSFVEQCEEFWAVQDINLNIQQGDRIALLGRNGAG
KSTLLKLISRITEPTTGKIKIRGRVSCLLEVGTGFHPDLTGRENIFLNGAIMGMSYQEIQTKFDEIVDFAEIEKFLDTPI
KKYSSGMYMRLGFAIAAHLNSDLLIVDEVLAVGDAQFQEKCIKKMNEMGMQGSTVLFVSHSVSSVLSLCNKGAFLEKGRL
KALEPIETCVNRYINSCPAAGLEWKGTLGDEHVQFFQTKLSTPKSSSALFYHDEQAIISIDFEILKTQPDLILGISILNS
RNQIIARSRLCDHDEYYDLISKMGRHHLNYALDPSLFHPGEYQIRLECSILNKKKILQGEILLKFIVYSSQIQQSKYEFG
TDKDGISLGNRWFLSKHL
>Mature_418_residues
MNIVEIEQLSKKYLISHENQNPYASLKEIATDWFKNSFKRLTSPSTSFVEQCEEFWAVQDINLNIQQGDRIALLGRNGAG
KSTLLKLISRITEPTTGKIKIRGRVSCLLEVGTGFHPDLTGRENIFLNGAIMGMSYQEIQTKFDEIVDFAEIEKFLDTPI
KKYSSGMYMRLGFAIAAHLNSDLLIVDEVLAVGDAQFQEKCIKKMNEMGMQGSTVLFVSHSVSSVLSLCNKGAFLEKGRL
KALEPIETCVNRYINSCPAAGLEWKGTLGDEHVQFFQTKLSTPKSSSALFYHDEQAIISIDFEILKTQPDLILGISILNS
RNQIIARSRLCDHDEYYDLISKMGRHHLNYALDPSLFHPGEYQIRLECSILNKKKILQGEILLKFIVYSSQIQQSKYEFG
TDKDGISLGNRWFLSKHL

Specific function: May form an ATP-driven O-antigen export apparatus, in association with RfbA [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=207, Percent_Identity=28.5024154589372, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI27477115, Length=209, Percent_Identity=24.8803827751196, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=29.2452830188679, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI153792144, Length=211, Percent_Identity=23.2227488151659, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI6005701, Length=209, Percent_Identity=24.4019138755981, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI45446740, Length=208, Percent_Identity=27.4038461538462, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI47078218, Length=208, Percent_Identity=27.4038461538462, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI105990541, Length=208, Percent_Identity=25.9615384615385, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI30795238, Length=209, Percent_Identity=23.9234449760766, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27881501, Length=209, Percent_Identity=23.9234449760766, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI116734710, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27262624, Length=210, Percent_Identity=21.4285714285714, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI27262626, Length=210, Percent_Identity=21.4285714285714, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081709, Length=243, Percent_Identity=26.3374485596708, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789032, Length=220, Percent_Identity=24.0909090909091, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787029, Length=198, Percent_Identity=25.2525252525253, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788210, Length=219, Percent_Identity=27.8538812785388, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790467, Length=244, Percent_Identity=23.3606557377049, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081791, Length=194, Percent_Identity=23.1958762886598, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788450, Length=196, Percent_Identity=27.5510204081633, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790525, Length=202, Percent_Identity=25.2475247524752, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787089, Length=203, Percent_Identity=23.1527093596059, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=195, Percent_Identity=25.1282051282051, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48995001, Length=209, Percent_Identity=23.9234449760766, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789672, Length=204, Percent_Identity=24.0196078431373, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789873, Length=183, Percent_Identity=29.5081967213115, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI48994943, Length=200, Percent_Identity=23, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=220, Percent_Identity=24.5454545454545, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=204, Percent_Identity=25.9803921568627, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=238, Percent_Identity=25.6302521008403, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=238, Percent_Identity=25.6302521008403, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=238, Percent_Identity=25.6302521008403, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=23.963133640553, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007184, Length=187, Percent_Identity=26.7379679144385, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221500365, Length=187, Percent_Identity=26.7379679144385, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24666092, Length=212, Percent_Identity=28.7735849056604, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648314, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512771, Length=206, Percent_Identity=24.7572815533981, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 47314; Mature: 47314

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVEIEQLSKKYLISHENQNPYASLKEIATDWFKNSFKRLTSPSTSFVEQCEEFWAVQD
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEEE
INLNIQQGDRIALLGRNGAGKSTLLKLISRITEPTTGKIKIRGRVSCLLEVGTGFHPDLT
CEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCCCC
GRENIFLNGAIMGMSYQEIQTKFDEIVDFAEIEKFLDTPIKKYSSGMYMRLGFAIAAHLN
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHCC
SDLLIVDEVLAVGDAQFQEKCIKKMNEMGMQGSTVLFVSHSVSSVLSLCNKGAFLEKGRL
CCEEEHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCC
KALEPIETCVNRYINSCPAAGLEWKGTLGDEHVQFFQTKLSTPKSSSALFYHDEQAIISI
CCCCHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEEE
DFEILKTQPDLILGISILNSRNQIIARSRLCDHDEYYDLISKMGRHHLNYALDPSLFHPG
EEEEECCCCCEEEEEEHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEECCCCCCCCC
EYQIRLECSILNKKKILQGEILLKFIVYSSQIQQSKYEFGTDKDGISLGNRWFLSKHL
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MNIVEIEQLSKKYLISHENQNPYASLKEIATDWFKNSFKRLTSPSTSFVEQCEEFWAVQD
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEEE
INLNIQQGDRIALLGRNGAGKSTLLKLISRITEPTTGKIKIRGRVSCLLEVGTGFHPDLT
CEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCCCC
GRENIFLNGAIMGMSYQEIQTKFDEIVDFAEIEKFLDTPIKKYSSGMYMRLGFAIAAHLN
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHHHHHCC
SDLLIVDEVLAVGDAQFQEKCIKKMNEMGMQGSTVLFVSHSVSSVLSLCNKGAFLEKGRL
CCEEEHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCC
KALEPIETCVNRYINSCPAAGLEWKGTLGDEHVQFFQTKLSTPKSSSALFYHDEQAIISI
CCCCHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEEE
DFEILKTQPDLILGISILNSRNQIIARSRLCDHDEYYDLISKMGRHHLNYALDPSLFHPG
EEEEECCCCCEEEEEEHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEECCCCCCCCC
EYQIRLECSILNKKKILQGEILLKFIVYSSQIQQSKYEFGTDKDGISLGNRWFLSKHL
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8626291 [H]