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The map label for this gene is gpsA

Identifier: 46445717

GI number: 46445717

Start: 142294

End: 143295

Strand: Reverse

Name: gpsA

Synonym: pc0083

Alternate gene names: 46445717

Gene position: 143295-142294 (Counterclockwise)

Preceding gene: 46445718

Following gene: 46445716

Centisome position: 5.93

GC content: 38.82

Gene sequence:

>1002_bases
ATGAAAAAAATTGGCTACCTTGGATTAGGGGCTTGGGGTTATTGCCTAGCTTCTTTACTAGCTTCAAAGGGGCATAAAGT
TGTCTGTTGGACAACAAAACCTGAATTAGCAAAACATCTAACGGATACGAGAGAACATCCTCTTTTAGCAGGTCATCTAT
CAAAAGGAGAAATGACTTTCACAACAGATATGTCTGAAGCTTTAAAAGATGTGGATATGATTGTTGAATCAGTCACCTCT
GCAGGTTTACGCTCTGTATTTGAACAAGTACGCTCTTTAGGATTACCTAATTGCCCTATTGTCATTACTTCCAAAGGGAT
TGAGCAAGATACAGGAATGATCCTACCAGAAGTCGTTATTGAAGTTTTAGGTGAAGAGTTTAGATCATTGATAGGTTTTT
TAAGCGGTCCTAGTTTTGCACAAGAAGTCATTCGTGAACTCCCAACTTCTGTCGTTGGAACGGGTTACACGGTCGAAGTC
ATCCAAGAGATTTGTGAAACATTTATGACCCCTACTTTTCGAGTCTATCCTAACACTGATATTTTAGGAGTCGCATTTGG
AGGAGCTTTAAAAAATATTATTGGCATTGCTTGTGGGATTTCCGATGGCCTAGCATTGGGATGCAGCTCCAAAGCAGCTT
TAATGACGCGAGGTCTGCACGAAATTCGAAAATTATCCGTTGCATGTGGTTGTAAAGCAGAAACATTAAATGGGCTAGCA
GGAATGGGTGATTTATGTGTGACTTGTAGTTCGCCTATTAGTCGCAATTTTCGTTTTGGTACACTTTTAGCCCAAGGGCT
ATCCACAGAACAAGCAAGAAATCGAATTGGTATGGTTGTAGAAGGAGCTTATACGTGTGTTTCAGCATTGCAATTAAGTA
AACAACATAAAATTATCATGCCAATTTCTGAAGCCGTTTATAATATTATTCAAGGGACTATTAAACCTATTGAAGCTGTG
AGTGCATTAATGAAAAGAACGATCAAAGAAGAGCATTTATAA

Upstream 100 bases:

>100_bases
TTGCTTGTTAGCAGATTGGACAGTCAGAAATTCAAATCTTTATAAAATAAAATGAGAGATCTTTTTTCTTGGAGATCAAG
ATGACATCGAAAGGATTGGT

Downstream 100 bases:

>100_bases
AATCATGCAAGTCTTATCAGCCCAAGCGGTATCGGAATTAGAAAAATCAGCTATTAAGCAGGGTTTTAGTGCATTAGATT
TTATGGAAAAAGCTGGATAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKKIGYLGLGAWGYCLASLLASKGHKVVCWTTKPELAKHLTDTREHPLLAGHLSKGEMTFTTDMSEALKDVDMIVESVTS
AGLRSVFEQVRSLGLPNCPIVITSKGIEQDTGMILPEVVIEVLGEEFRSLIGFLSGPSFAQEVIRELPTSVVGTGYTVEV
IQEICETFMTPTFRVYPNTDILGVAFGGALKNIIGIACGISDGLALGCSSKAALMTRGLHEIRKLSVACGCKAETLNGLA
GMGDLCVTCSSPISRNFRFGTLLAQGLSTEQARNRIGMVVEGAYTCVSALQLSKQHKIIMPISEAVYNIIQGTIKPIEAV
SALMKRTIKEEHL

Sequences:

>Translated_333_residues
MKKIGYLGLGAWGYCLASLLASKGHKVVCWTTKPELAKHLTDTREHPLLAGHLSKGEMTFTTDMSEALKDVDMIVESVTS
AGLRSVFEQVRSLGLPNCPIVITSKGIEQDTGMILPEVVIEVLGEEFRSLIGFLSGPSFAQEVIRELPTSVVGTGYTVEV
IQEICETFMTPTFRVYPNTDILGVAFGGALKNIIGIACGISDGLALGCSSKAALMTRGLHEIRKLSVACGCKAETLNGLA
GMGDLCVTCSSPISRNFRFGTLLAQGLSTEQARNRIGMVVEGAYTCVSALQLSKQHKIIMPISEAVYNIIQGTIKPIEAV
SALMKRTIKEEHL
>Mature_333_residues
MKKIGYLGLGAWGYCLASLLASKGHKVVCWTTKPELAKHLTDTREHPLLAGHLSKGEMTFTTDMSEALKDVDMIVESVTS
AGLRSVFEQVRSLGLPNCPIVITSKGIEQDTGMILPEVVIEVLGEEFRSLIGFLSGPSFAQEVIRELPTSVVGTGYTVEV
IQEICETFMTPTFRVYPNTDILGVAFGGALKNIIGIACGISDGLALGCSSKAALMTRGLHEIRKLSVACGCKAETLNGLA
GMGDLCVTCSSPISRNFRFGTLLAQGLSTEQARNRIGMVVEGAYTCVSALQLSKQHKIIMPISEAVYNIIQGTIKPIEAV
SALMKRTIKEEHL

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=330, Percent_Identity=25.1515151515152, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI24307999, Length=329, Percent_Identity=26.4437689969605, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=35.7575757575758, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17507425, Length=270, Percent_Identity=25.1851851851852, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564399, Length=348, Percent_Identity=24.4252873563218, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324513, Length=352, Percent_Identity=26.7045454545455, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=342, Percent_Identity=26.0233918128655, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_PARUW (Q6MF42)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007082.1
- ProteinModelPortal:   Q6MF42
- SMR:   Q6MF42
- STRING:   Q6MF42
- GeneID:   2780166
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0083
- NMPDR:   fig|264201.1.peg.83
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- PhylomeDB:   Q6MF42
- ProtClustDB:   PRK00094
- BioCyc:   CPRO264201:PC0083-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35754; Mature: 35754

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 105-105 BINDING 105-105 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIGYLGLGAWGYCLASLLASKGHKVVCWTTKPELAKHLTDTREHPLLAGHLSKGEMTF
CCCCCEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCEEE
TTDMSEALKDVDMIVESVTSAGLRSVFEQVRSLGLPNCPIVITSKGIEQDTGMILPEVVI
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHH
EVLGEEFRSLIGFLSGPSFAQEVIRELPTSVVGTGYTVEVIQEICETFMTPTFRVYPNTD
HHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCC
ILGVAFGGALKNIIGIACGISDGLALGCSSKAALMTRGLHEIRKLSVACGCKAETLNGLA
EEEEHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
GMGDLCVTCSSPISRNFRFGTLLAQGLSTEQARNRIGMVVEGAYTCVSALQLSKQHKIIM
CCCCCEEECCCCHHCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEE
PISEAVYNIIQGTIKPIEAVSALMKRTIKEEHL
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIGYLGLGAWGYCLASLLASKGHKVVCWTTKPELAKHLTDTREHPLLAGHLSKGEMTF
CCCCCEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCEEE
TTDMSEALKDVDMIVESVTSAGLRSVFEQVRSLGLPNCPIVITSKGIEQDTGMILPEVVI
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHH
EVLGEEFRSLIGFLSGPSFAQEVIRELPTSVVGTGYTVEVIQEICETFMTPTFRVYPNTD
HHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCC
ILGVAFGGALKNIIGIACGISDGLALGCSSKAALMTRGLHEIRKLSVACGCKAETLNGLA
EEEEHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
GMGDLCVTCSSPISRNFRFGTLLAQGLSTEQARNRIGMVVEGAYTCVSALQLSKQHKIIM
CCCCCEEECCCCHHCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEE
PISEAVYNIIQGTIKPIEAVSALMKRTIKEEHL
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA