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The map label for this gene is copA [H]

Identifier: 46445712

GI number: 46445712

Start: 136133

End: 138322

Strand: Direct

Name: copA [H]

Synonym: pc0078

Alternate gene names: 46445712

Gene position: 136133-138322 (Clockwise)

Preceding gene: 46445711

Following gene: 46445713

Centisome position: 5.64

GC content: 35.53

Gene sequence:

>2190_bases
ATGGAGAAAAAAAAATTGTTAATTCGAGGGATGCACTGTGTTTCATGCGCGCAAAATCTTGAAAACAGTTTGAAGAAAGT
TTCTGGATTACAAGAGATTCATGTTGATTATTCGACTAGTCAAGCTGATATTATTTTTGACGAAAACAAAGTTTCATTTG
CCTCACTAGAAAAGCATATAAAAAAAATGGGATATGAGAGTTATTCATTTAGGCCTTCTTTAGATGAAGATAGACGAATA
AAGCAAAAAGAAATTCAAAATACTTTTAAAACCTTTTTGATCGCTGCTGTTTTGTCTTTGCCTTTTGTGATTCAGATGTT
GGCGATGATGTTAGGATATGCTTTTTCCATTCCTCCAACATGGCAATTTTTTTTAGCCACCCTTGTACAATTTGGGTGTG
GAGGAACATTTTATCGATCCTCTTTTTATGCTCTTAAAAACTGGCAAATTAATATGGATGTTTTGGTTGTTTTGGGATCA
ACTGCGGCTTATCTATTTAGCTTTTATGTTTATCTTTTAAAACTTTCTTACTCTTTTTATTTTGAAAGTAGCGCGCTCAT
TATTACATTGATTTTATTTGGACGTTGGTTAGAAGCCGTCACTAAAGGAAAAACCTCTAAAGCACTAGAGCGTTTATATC
ATTTACAGCCTAAAATTGCTCGTATTGAAAAAAATGGTGAAATTATAGAGGTTGATGTTGCCTCGATTCAAGTAGGTGAT
ATTTTTATGGTACGTCCTGGAGATCATATTCCAGTTGATGGATGGGTGATAGAAGGAGAGTCTTCCATCAATGAATCTTT
GTTAACGGGAGAAAGTTTGCCGGTTTATAAGAAACAGGGATCGAAACTTTATGCAGCGACAATCAATGAAACTGGTTACT
TGAAAGGGCAGGCCTCTTCAGTTGGATCCGATACAATTTTAGCTCAGATACTTCGAGCTGTAGAAAAAGCTCAATCTTCG
AAAGCACCTATTCAAAAATTTGTGGATAAAATTTCTGCAGTTTTCGTTCCCTGCGTACTTCTAATCAGTTGTTTGACGAT
ATTAATTTGGACATTTCTAATAGGTGATTTTACAAATGGATTGATTAATGCGGTCTCTGTTCTAGTGATTGCATGCCCTT
GTGTTTTAGGATTAGCCACGCCGGCAGTTCTTGTGGTAGCAAGTGGGGTTGGAGCACAATACGGAATATTTTTTAAACAA
GCTTCATCGATCGAGCAGTCTGAAAAAATCAAATTTTTATTTTTAGATAAGACCGGTACCTTAACGAAAGGAATTCCTTC
TGTGATGGGAATCTATCCAAATGCCAAATATCTTAAAAATGACGTATTACAAATAGCAGCTTCGCTTGAAAATTGCTCTT
CCCATCCTTTAGCTAAGGCTATATTAAATGAGGCCAAAGAAGAGGGAATTCTTTTAAAAATTGTCAAAGAATTTAATTCA
TTTATTGGAAAAGGAGTTACAGGAACAATTGATGAAAAGGTTTATTATTTAGGCTCTGCTAACTTTGCAAAAGAAATGGG
AATTGAAATCGACCCTGCTTTTTCTCTTCTTGAAGAACAAGGAGAATCACTGGTCTTTGTTTGGACAGACCATCAATTAT
TAGGCATGATTACCATCATGGATGAGCTAAGAAAGGAAAGTATGGAAGTAATTCGTTTGTTGAAATTGAAAGGAATTTAT
CCCATCCTTTTAACTGGAGATCGAAAATATGTTGCTGAAACTATTGCAAAAAAATTGGGGATTGAAGATGCGCGGTTTGA
ATTGCTTCCAGACGATAAAATGCAGATTATCCGAGAAGCTAAAAATAGTGGAAAAGTAGGAATGATTGGAGACGGAATTA
ACGATGCTCCAGCCCTTGCAGAAGCTGATGTGAGTTTTGCTCTTGCCTTTGGTAGCGATATTGCTATTGAAGTCGCTGAT
ATTACTTTAATACGAAATGATTTAATGAGTTTAGTGGACGCTATAGATCTTTCCCAGCAAACCATGCGTAAAATGAAATA
TAATTTATTTTTAGCATTTATTTATAATGTTCTTGCGATTCCTTTGGCAGCTTTTGGACTACTTAATCCAATGATTGCGG
CAGGAACAATGGCAATGAGCTCTGTTTCTGTGATCGCCAATGCGTTATTACTACGTTATTGGAAGCCAGAAATAAATAGA
AATAATGTGGAGAGGATTGTCAAAGTTTAA

Upstream 100 bases:

>100_bases
GTAAGAAAGGACGTATTTCTATTGATTATTATAACCTTGATGATTTAGATCGGCTGTTAGATATATTTGGAATAAAAGAT
TAATTAAGACTGAGGATAGA

Downstream 100 bases:

>100_bases
AATGGGAAAACAAATTTTTATTACAGGAATAGCCGGATTCATTGGCTTTCACCTCGCGCAAAAACTTGCAAAAAGAGGAG
ATCGTATCATTGGATATGAT

Product: putative copper-transporting ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MEKKKLLIRGMHCVSCAQNLENSLKKVSGLQEIHVDYSTSQADIIFDENKVSFASLEKHIKKMGYESYSFRPSLDEDRRI
KQKEIQNTFKTFLIAAVLSLPFVIQMLAMMLGYAFSIPPTWQFFLATLVQFGCGGTFYRSSFYALKNWQINMDVLVVLGS
TAAYLFSFYVYLLKLSYSFYFESSALIITLILFGRWLEAVTKGKTSKALERLYHLQPKIARIEKNGEIIEVDVASIQVGD
IFMVRPGDHIPVDGWVIEGESSINESLLTGESLPVYKKQGSKLYAATINETGYLKGQASSVGSDTILAQILRAVEKAQSS
KAPIQKFVDKISAVFVPCVLLISCLTILIWTFLIGDFTNGLINAVSVLVIACPCVLGLATPAVLVVASGVGAQYGIFFKQ
ASSIEQSEKIKFLFLDKTGTLTKGIPSVMGIYPNAKYLKNDVLQIAASLENCSSHPLAKAILNEAKEEGILLKIVKEFNS
FIGKGVTGTIDEKVYYLGSANFAKEMGIEIDPAFSLLEEQGESLVFVWTDHQLLGMITIMDELRKESMEVIRLLKLKGIY
PILLTGDRKYVAETIAKKLGIEDARFELLPDDKMQIIREAKNSGKVGMIGDGINDAPALAEADVSFALAFGSDIAIEVAD
ITLIRNDLMSLVDAIDLSQQTMRKMKYNLFLAFIYNVLAIPLAAFGLLNPMIAAGTMAMSSVSVIANALLLRYWKPEINR
NNVERIVKV

Sequences:

>Translated_729_residues
MEKKKLLIRGMHCVSCAQNLENSLKKVSGLQEIHVDYSTSQADIIFDENKVSFASLEKHIKKMGYESYSFRPSLDEDRRI
KQKEIQNTFKTFLIAAVLSLPFVIQMLAMMLGYAFSIPPTWQFFLATLVQFGCGGTFYRSSFYALKNWQINMDVLVVLGS
TAAYLFSFYVYLLKLSYSFYFESSALIITLILFGRWLEAVTKGKTSKALERLYHLQPKIARIEKNGEIIEVDVASIQVGD
IFMVRPGDHIPVDGWVIEGESSINESLLTGESLPVYKKQGSKLYAATINETGYLKGQASSVGSDTILAQILRAVEKAQSS
KAPIQKFVDKISAVFVPCVLLISCLTILIWTFLIGDFTNGLINAVSVLVIACPCVLGLATPAVLVVASGVGAQYGIFFKQ
ASSIEQSEKIKFLFLDKTGTLTKGIPSVMGIYPNAKYLKNDVLQIAASLENCSSHPLAKAILNEAKEEGILLKIVKEFNS
FIGKGVTGTIDEKVYYLGSANFAKEMGIEIDPAFSLLEEQGESLVFVWTDHQLLGMITIMDELRKESMEVIRLLKLKGIY
PILLTGDRKYVAETIAKKLGIEDARFELLPDDKMQIIREAKNSGKVGMIGDGINDAPALAEADVSFALAFGSDIAIEVAD
ITLIRNDLMSLVDAIDLSQQTMRKMKYNLFLAFIYNVLAIPLAAFGLLNPMIAAGTMAMSSVSVIANALLLRYWKPEINR
NNVERIVKV
>Mature_729_residues
MEKKKLLIRGMHCVSCAQNLENSLKKVSGLQEIHVDYSTSQADIIFDENKVSFASLEKHIKKMGYESYSFRPSLDEDRRI
KQKEIQNTFKTFLIAAVLSLPFVIQMLAMMLGYAFSIPPTWQFFLATLVQFGCGGTFYRSSFYALKNWQINMDVLVVLGS
TAAYLFSFYVYLLKLSYSFYFESSALIITLILFGRWLEAVTKGKTSKALERLYHLQPKIARIEKNGEIIEVDVASIQVGD
IFMVRPGDHIPVDGWVIEGESSINESLLTGESLPVYKKQGSKLYAATINETGYLKGQASSVGSDTILAQILRAVEKAQSS
KAPIQKFVDKISAVFVPCVLLISCLTILIWTFLIGDFTNGLINAVSVLVIACPCVLGLATPAVLVVASGVGAQYGIFFKQ
ASSIEQSEKIKFLFLDKTGTLTKGIPSVMGIYPNAKYLKNDVLQIAASLENCSSHPLAKAILNEAKEEGILLKIVKEFNS
FIGKGVTGTIDEKVYYLGSANFAKEMGIEIDPAFSLLEEQGESLVFVWTDHQLLGMITIMDELRKESMEVIRLLKLKGIY
PILLTGDRKYVAETIAKKLGIEDARFELLPDDKMQIIREAKNSGKVGMIGDGINDAPALAEADVSFALAFGSDIAIEVAD
ITLIRNDLMSLVDAIDLSQQTMRKMKYNLFLAFIYNVLAIPLAAFGLLNPMIAAGTMAMSSVSVIANALLLRYWKPEINR
NNVERIVKV

Specific function: Involved in copper export [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=782, Percent_Identity=34.0153452685422, Blast_Score=420, Evalue=1e-117,
Organism=Homo sapiens, GI115529486, Length=815, Percent_Identity=32.8834355828221, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI55743073, Length=552, Percent_Identity=35.8695652173913, Blast_Score=301, Evalue=2e-81,
Organism=Escherichia coli, GI1786691, Length=742, Percent_Identity=37.0619946091644, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1789879, Length=711, Percent_Identity=27.4261603375527, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1786914, Length=505, Percent_Identity=27.3267326732673, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI2367363, Length=578, Percent_Identity=23.356401384083, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556548, Length=793, Percent_Identity=32.6607818411097, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI71997275, Length=208, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997262, Length=208, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997269, Length=167, Percent_Identity=31.1377245508982, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193210130, Length=169, Percent_Identity=26.0355029585799, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554158, Length=169, Percent_Identity=26.0355029585799, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988506, Length=169, Percent_Identity=26.0355029585799, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=772, Percent_Identity=31.4766839378238, Blast_Score=349, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6319772, Length=682, Percent_Identity=31.524926686217, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6321430, Length=520, Percent_Identity=25, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325221, Length=524, Percent_Identity=25, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6321271, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221329854, Length=516, Percent_Identity=35.4651162790698, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI45553437, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648576, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553435, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553439, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553441, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648580, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648578, Length=292, Percent_Identity=22.6027397260274, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362164, Length=292, Percent_Identity=22.6027397260274, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648582, Length=292, Percent_Identity=22.6027397260274, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24668708, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668704, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281366617, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161085803, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668696, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 80681; Mature: 80681

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKKLLIRGMHCVSCAQNLENSLKKVSGLQEIHVDYSTSQADIIFDENKVSFASLEKHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEECCCCHHHHHHHHH
KKMGYESYSFRPSLDEDRRIKQKEIQNTFKTFLIAAVLSLPFVIQMLAMMLGYAFSIPPT
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WQFFLATLVQFGCGGTFYRSSFYALKNWQINMDVLVVLGSTAAYLFSFYVYLLKLSYSFY
HHHHHHHHHHHCCCCHHHHHHEEEEECCEECEEEEEEECCHHHHHHHHHHHHHHHHHHHE
FESSALIITLILFGRWLEAVTKGKTSKALERLYHLQPKIARIEKNGEIIEVDVASIQVGD
ECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEEEECC
IFMVRPGDHIPVDGWVIEGESSINESLLTGESLPVYKKQGSKLYAATINETGYLKGQASS
EEEECCCCCCCCCCEEECCCCCCCHHHHCCCCCCCHHCCCCEEEEEEECCCCCCCCCCCC
VGSDTILAQILRAVEKAQSSKAPIQKFVDKISAVFVPCVLLISCLTILIWTFLIGDFTNG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINAVSVLVIACPCVLGLATPAVLVVASGVGAQYGIFFKQASSIEQSEKIKFLFLDKTGT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCC
LTKGIPSVMGIYPNAKYLKNDVLQIAASLENCSSHPLAKAILNEAKEEGILLKIVKEFNS
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
FIGKGVTGTIDEKVYYLGSANFAKEMGIEIDPAFSLLEEQGESLVFVWTDHQLLGMITIM
HHCCCCCCCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHH
DELRKESMEVIRLLKLKGIYPILLTGDRKYVAETIAKKLGIEDARFELLPDDKMQIIREA
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHH
KNSGKVGMIGDGINDAPALAEADVSFALAFGSDIAIEVADITLIRNDLMSLVDAIDLSQQ
HCCCCEEEECCCCCCCCCHHHCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCHH
TMRKMKYNLFLAFIYNVLAIPLAAFGLLNPMIAAGTMAMSSVSVIANALLLRYWKPEINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NNVERIVKV
CCHHHHHCC
>Mature Secondary Structure
MEKKKLLIRGMHCVSCAQNLENSLKKVSGLQEIHVDYSTSQADIIFDENKVSFASLEKHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEECCCCHHHHHHHHH
KKMGYESYSFRPSLDEDRRIKQKEIQNTFKTFLIAAVLSLPFVIQMLAMMLGYAFSIPPT
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WQFFLATLVQFGCGGTFYRSSFYALKNWQINMDVLVVLGSTAAYLFSFYVYLLKLSYSFY
HHHHHHHHHHHCCCCHHHHHHEEEEECCEECEEEEEEECCHHHHHHHHHHHHHHHHHHHE
FESSALIITLILFGRWLEAVTKGKTSKALERLYHLQPKIARIEKNGEIIEVDVASIQVGD
ECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEEEECC
IFMVRPGDHIPVDGWVIEGESSINESLLTGESLPVYKKQGSKLYAATINETGYLKGQASS
EEEECCCCCCCCCCEEECCCCCCCHHHHCCCCCCCHHCCCCEEEEEEECCCCCCCCCCCC
VGSDTILAQILRAVEKAQSSKAPIQKFVDKISAVFVPCVLLISCLTILIWTFLIGDFTNG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINAVSVLVIACPCVLGLATPAVLVVASGVGAQYGIFFKQASSIEQSEKIKFLFLDKTGT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCC
LTKGIPSVMGIYPNAKYLKNDVLQIAASLENCSSHPLAKAILNEAKEEGILLKIVKEFNS
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
FIGKGVTGTIDEKVYYLGSANFAKEMGIEIDPAFSLLEEQGESLVFVWTDHQLLGMITIM
HHCCCCCCCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHH
DELRKESMEVIRLLKLKGIYPILLTGDRKYVAETIAKKLGIEDARFELLPDDKMQIIREA
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHH
KNSGKVGMIGDGINDAPALAEADVSFALAFGSDIAIEVADITLIRNDLMSLVDAIDLSQQ
HCCCCEEEECCCCCCCCCHHHCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCHH
TMRKMKYNLFLAFIYNVLAIPLAAFGLLNPMIAAGTMAMSSVSVIANALLLRYWKPEINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NNVERIVKV
CCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA