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The map label for this gene is aspC [H]

Identifier: 161611311

GI number: 161611311

Start: 126400

End: 127596

Strand: Reverse

Name: aspC [H]

Synonym: pc0069

Alternate gene names: 161611311

Gene position: 127596-126400 (Counterclockwise)

Preceding gene: 46445704

Following gene: 46445702

Centisome position: 5.28

GC content: 34.34

Gene sequence:

>1197_bases
ATGCCTTTTTTTAATAATATTTCTCTTTTGCCACCAGACCCAATTTTAAATCTTTCTATAGACTTCTCTCTTGATCAAAA
TCCTCAAAAAATTAATTTGAGTGCAGGAACTTATAAAACTGCAGATGGGCATTCGCTAGTTTTCACCAGTGTCCGAAAAG
CAGAAATTGATCTGCTTCAAAAACATCTCAATAAAGATTATCAACCGATAGAGGGAAATAGTGTTTTCCTAAAAAATTCT
TTAGAGCTGTTATTTGGTTCAGACCACGCTTTGTTTACCAATAAAAAATTTTTTGCTGTTCAAACCGTTGGAGGAACAAG
CGCTTTAAGATTAGGAGGAGAGTTTTTAAATAAGCTTACTTGCCAAAAAATTTTTATTTCTCAACCATCGTGGCCAAACC
ACAAACAGGTTTTTGAAAAAACAGGTTTAAAAATTGATTCCTATCCTTACTTCGATTTTAATGCATACAAATTAAATTTT
TCAGGGATGTGCCAAGCCATCCGCCAAATGCCAACTGGAAGCGTTATCCTTCTGCATGGTTGCTGTCACAATCCATCAGG
GGTCGATCCAACTTTTGAACAATGGAAAGAGCTTTCTCAGCTTATTAAAAAACATGAACTCATTCCTTTTTTTGATATCG
CTTATCAAGGATTTGGGAAAGATTTAGAACTCGATGCACAACCTATTCGGTACTTTGCTAGTGAAGGCCATGAAATGTTG
ATCGCTTACTCTTTTTCTAAAAATTTTGGTTTATACGGGGAACGAGTAGGTTTTTTGACTGTTGTGACATCTCAACAAAA
ACAAATACCATCTATAGCTAGTCAATTAAAGGTTTTAATTCGTGCTAATTACTCCAATCCTCCTCTTCAAGGAGCTCGAA
TTGTTTCTACAATCTTGAGTTCACCAGAATTAACCGAAGAATGGAAAATAGAATTAAAAAATATGCGTGACCGAGTTGTT
GAAATGCGGAAAACATTTATTGCTTCTTTGTTAGTCAAAGGAGAAGATAAAAATTTAAACTACTTGCAACAACAAATTGG
TTTATTTGGTTTTTGTGGATTAAATTATTCCCAAGTCAATCGTTTGCGGAAAGAATTTGCTATTTATATTCCTAGCGACG
GACGAATCAATATTGCAGGATTAAACACTCAAAATATTGAATATGTAGTCAATGCAATTTCATCTGTTATGGAGTAG

Upstream 100 bases:

>100_bases
GGTTTTTAAAAAATTCAGGAAAGTTCTGCATTCGAAGTAATTAGACATTTAGATAAACAATTGACATAGCTTTATTATGT
CATTTGAGATAAGGGATCCC

Downstream 100 bases:

>100_bases
TGAAGGCTCCCGCTTACAGGTGAAAGCTTCTAAAATCCATTCTCAGGCCAACTAATCCGAAGGATAAAATATTTTGCACT
GCGTTAAAATCTCTTAAAGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MPFFNNISLLPPDPILNLSIDFSLDQNPQKINLSAGTYKTADGHSLVFTSVRKAEIDLLQKHLNKDYQPIEGNSVFLKNS
LELLFGSDHALFTNKKFFAVQTVGGTSALRLGGEFLNKLTCQKIFISQPSWPNHKQVFEKTGLKIDSYPYFDFNAYKLNF
SGMCQAIRQMPTGSVILLHGCCHNPSGVDPTFEQWKELSQLIKKHELIPFFDIAYQGFGKDLELDAQPIRYFASEGHEML
IAYSFSKNFGLYGERVGFLTVVTSQQKQIPSIASQLKVLIRANYSNPPLQGARIVSTILSSPELTEEWKIELKNMRDRVV
EMRKTFIASLLVKGEDKNLNYLQQQIGLFGFCGLNYSQVNRLRKEFAIYIPSDGRINIAGLNTQNIEYVVNAISSVME

Sequences:

>Translated_398_residues
MPFFNNISLLPPDPILNLSIDFSLDQNPQKINLSAGTYKTADGHSLVFTSVRKAEIDLLQKHLNKDYQPIEGNSVFLKNS
LELLFGSDHALFTNKKFFAVQTVGGTSALRLGGEFLNKLTCQKIFISQPSWPNHKQVFEKTGLKIDSYPYFDFNAYKLNF
SGMCQAIRQMPTGSVILLHGCCHNPSGVDPTFEQWKELSQLIKKHELIPFFDIAYQGFGKDLELDAQPIRYFASEGHEML
IAYSFSKNFGLYGERVGFLTVVTSQQKQIPSIASQLKVLIRANYSNPPLQGARIVSTILSSPELTEEWKIELKNMRDRVV
EMRKTFIASLLVKGEDKNLNYLQQQIGLFGFCGLNYSQVNRLRKEFAIYIPSDGRINIAGLNTQNIEYVVNAISSVME
>Mature_397_residues
PFFNNISLLPPDPILNLSIDFSLDQNPQKINLSAGTYKTADGHSLVFTSVRKAEIDLLQKHLNKDYQPIEGNSVFLKNSL
ELLFGSDHALFTNKKFFAVQTVGGTSALRLGGEFLNKLTCQKIFISQPSWPNHKQVFEKTGLKIDSYPYFDFNAYKLNFS
GMCQAIRQMPTGSVILLHGCCHNPSGVDPTFEQWKELSQLIKKHELIPFFDIAYQGFGKDLELDAQPIRYFASEGHEMLI
AYSFSKNFGLYGERVGFLTVVTSQQKQIPSIASQLKVLIRANYSNPPLQGARIVSTILSSPELTEEWKIELKNMRDRVVE
MRKTFIASLLVKGEDKNLNYLQQQIGLFGFCGLNYSQVNRLRKEFAIYIPSDGRINIAGLNTQNIEYVVNAISSVME

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=399, Percent_Identity=42.1052631578947, Blast_Score=358, Evalue=4e-99,
Organism=Homo sapiens, GI4504067, Length=403, Percent_Identity=42.6799007444169, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI117414139, Length=380, Percent_Identity=32.8947368421053, Blast_Score=206, Evalue=5e-53,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=44.6969696969697, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=38.7909319899244, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=42.5, Blast_Score=361, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25147133, Length=398, Percent_Identity=42.2110552763819, Blast_Score=357, Evalue=8e-99,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=40.0497512437811, Blast_Score=330, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI17569537, Length=401, Percent_Identity=35.6608478802993, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI25147136, Length=212, Percent_Identity=39.622641509434, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17550384, Length=268, Percent_Identity=34.3283582089552, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=37.5921375921376, Blast_Score=296, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6322743, Length=424, Percent_Identity=32.7830188679245, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24580970, Length=399, Percent_Identity=40.8521303258145, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24580972, Length=399, Percent_Identity=40.8521303258145, Blast_Score=355, Evalue=2e-98,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=41.4322250639386, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI19922362, Length=401, Percent_Identity=40.8977556109726, Blast_Score=325, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24654046, Length=401, Percent_Identity=40.8977556109726, Blast_Score=324, Evalue=5e-89,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 45005; Mature: 44874

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFFNNISLLPPDPILNLSIDFSLDQNPQKINLSAGTYKTADGHSLVFTSVRKAEIDLLQ
CCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCCCEECCCCCEEEEEHHHHHHHHHHH
KHLNKDYQPIEGNSVFLKNSLELLFGSDHALFTNKKFFAVQTVGGTSALRLGGEFLNKLT
HHCCCCCCCCCCCEEEEECCEEEEECCCCEEEECCEEEEEEECCCCHHHHHHHHHHHHHH
CQKIFISQPSWPNHKQVFEKTGLKIDSYPYFDFNAYKLNFSGMCQAIRQMPTGSVILLHG
HHHHEECCCCCCCHHHHHHHHCCEECCCCCCCCEEEEECHHHHHHHHHHCCCCCEEEEEE
CCHNPSGVDPTFEQWKELSQLIKKHELIPFFDIAYQGFGKDLELDAQPIRYFASEGHEML
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEE
IAYSFSKNFGLYGERVGFLTVVTSQQKQIPSIASQLKVLIRANYSNPPLQGARIVSTILS
EEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHC
SPELTEEWKIELKNMRDRVVEMRKTFIASLLVKGEDKNLNYLQQQIGLFGFCGLNYSQVN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEEECCCHHHHH
RLRKEFAIYIPSDGRINIAGLNTQNIEYVVNAISSVME
HHHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PFFNNISLLPPDPILNLSIDFSLDQNPQKINLSAGTYKTADGHSLVFTSVRKAEIDLLQ
CCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCCCEECCCCCEEEEEHHHHHHHHHHH
KHLNKDYQPIEGNSVFLKNSLELLFGSDHALFTNKKFFAVQTVGGTSALRLGGEFLNKLT
HHCCCCCCCCCCCEEEEECCEEEEECCCCEEEECCEEEEEEECCCCHHHHHHHHHHHHHH
CQKIFISQPSWPNHKQVFEKTGLKIDSYPYFDFNAYKLNFSGMCQAIRQMPTGSVILLHG
HHHHEECCCCCCCHHHHHHHHCCEECCCCCCCCEEEEECHHHHHHHHHHCCCCCEEEEEE
CCHNPSGVDPTFEQWKELSQLIKKHELIPFFDIAYQGFGKDLELDAQPIRYFASEGHEML
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEE
IAYSFSKNFGLYGERVGFLTVVTSQQKQIPSIASQLKVLIRANYSNPPLQGARIVSTILS
EEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHC
SPELTEEWKIELKNMRDRVVEMRKTFIASLLVKGEDKNLNYLQQQIGLFGFCGLNYSQVN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEEECCCHHHHH
RLRKEFAIYIPSDGRINIAGLNTQNIEYVVNAISSVME
HHHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]