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The map label for this gene is hycC

Identifier: 45659236

GI number: 45659236

Start: 4194635

End: 4196356

Strand: Direct

Name: hycC

Synonym: LIC13419

Alternate gene names: 45659236

Gene position: 4194635-4196356 (Clockwise)

Preceding gene: 45659235

Following gene: 45659237

Centisome position: 98.07

GC content: 38.15

Gene sequence:

>1722_bases
ATGATTGTTTTATCTTATCTGATAGTCTTAATGTCGCTTGTTGCGCCTTTTTTAGCGGCAAAAGTACTCGGTAAAAATTT
TTTAGAGCAAGACTCGGTTTTATTTATTGCTCTTACTCTTCAAGCCGTTTTGGGATTCATTTCTTCCATTTATGTCTATG
GATATGAACATCGTAAAAGGACTACTGTACTCTTAGGATACTCCGTATTCTTTCTTAGTACAGGTCTTTGTTATTTAGTT
GGAAAGACATTATGGTTGATTCTATTTTGGGAATTGTCAACCGTCAACGCTTTTCTTCTTTATCAAGGAGGCAAATGGAC
TCCGAACTCCATCAAAAGTTTTATTGCGTTAGTCGTCGCGGGTGGAGTAGGAGCATTTTGTTTTACATATTGGATCTATT
CGCCTAAAAGCGAATTTGGAAATATGTTTTTGGTAGCCGGGCTTTTAGTCAAAGCTGCTTTTTTTGGTTTTCATTTTTGG
CTTCCAGAAGCACATTCCGGTTCTCCTGCTCATGCATCAGCTGCTTATTCCGGAATTCTTGTAAATCTTCCCTTGATTCT
TTTTCATCAACTCGTAGCACCTTGGTTCGGAAATACGATCTACATTAAAATCTTAATTCCCCTCGCGGGCTTTGGAGTTC
TCTGGGCGGGTCTTTCTTCCTTATTTTCAAGAGACGCAAAAAAGGCAATTGCTTATAGTACTGTAGAGAATATGAATTTT
TTATTTCTCTGCATTCTTCTTTCCGCCTTATGGAAAGACAGCGAAGTGGAAAGTTTAAAAGTGTTGAGCAGATCTTTTTC
GTTTTTGTTCATCTTATCTTTGATCCATCATAGTATTAGCAAAACGTTTCAATTTCTTTCGATCGGATACCTGACTAAAA
TATCAGGTTTTTCGAATGTAGATCAGAATACAGGAATAGGTAGAATTTCAGGACTTCCAACTTCTTTGTTAAGTTTGGGA
ACGATCAGTTTTCTTGCAATTCCAGGAACAACCGGATTTCTTTCCGAAGCCACCTTTGTAAAGTTAGTCGCAGGTGTTTT
GGAAATTCCAGGACAAAGCGCAATTCTGATTCTCCCACTTTTGATTTTGGTTTCCTCTGGTTTAGTCTTAGGTGCAGCAG
GACATTTAAGAATTTTCTTAGGAATGGTTTTATCCAGACCAAGAACAAACTGGCCGGAACACAAACCTTCCCGTTCAGTA
TTCTATTCTATTTTTTTTAGCGGTGTTTTGATCTTAATCGTTTCCTTTGGAATTTCAGCTTATGCTCTTTATCATTCACC
CACCAAAGAATGGTTAGATGAAGAGTGGTATAAAGGTCTTGCGATCGTGAACTTTATCGGACTCGGGATGATTATACTGG
TTGGAATTATGGGGTTGAGAACTAAAATTTCTAAAAGAAAACTTTGGGATTGCGGCGGGAATTATGGAGGCGCAGACATA
GCGATTCCTTCCGACGGAATTTCAGATCCTCTTTTCCCTTCTTTGGGAAGATACTTCACAAACGTAGAAGGTAATTCTCG
TTTGGACGAAGGAATACTTCAGGGAATTATAAAATTCTTAAATATGTTTAAGACCAAACCGAACGAAACAAACGAAGAAT
CGATTTCGATCAATCTCGCTTTTTCTTCCGTGACAGTGGTAATCCTTCTATTCGTAATTATCGGCCTGAAGTTGACCGAG
GGAGATTTATGGAAATTATTCTTAAATACCTTGACCCGATAA

Upstream 100 bases:

>100_bases
AAATTCCGCCGCGTTTATGAAACAACATACCTCAGCAAACAACGCGAGCGTATTTTTCTTTCAGTTGAACGCTGCACTTT
AAGAGGAGACTTAAAAGTCG

Downstream 100 bases:

>100_bases
TTCGGGTTTTGTCTTTTATCGTTCTTCCGTTTTTATGCGGAGGACTGGTTCAAAAAATAAGATCTTATTCTCAAGGAAGA
GTAGGCGCTCCCGTTTTTCA

Product: hydrogenase subunit

Products: NA

Alternate protein names: NAD(P)H dehydrogenase I, subunit D-2; NDH-1, chain 4-2 [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MIVLSYLIVLMSLVAPFLAAKVLGKNFLEQDSVLFIALTLQAVLGFISSIYVYGYEHRKRTTVLLGYSVFFLSTGLCYLV
GKTLWLILFWELSTVNAFLLYQGGKWTPNSIKSFIALVVAGGVGAFCFTYWIYSPKSEFGNMFLVAGLLVKAAFFGFHFW
LPEAHSGSPAHASAAYSGILVNLPLILFHQLVAPWFGNTIYIKILIPLAGFGVLWAGLSSLFSRDAKKAIAYSTVENMNF
LFLCILLSALWKDSEVESLKVLSRSFSFLFILSLIHHSISKTFQFLSIGYLTKISGFSNVDQNTGIGRISGLPTSLLSLG
TISFLAIPGTTGFLSEATFVKLVAGVLEIPGQSAILILPLLILVSSGLVLGAAGHLRIFLGMVLSRPRTNWPEHKPSRSV
FYSIFFSGVLILIVSFGISAYALYHSPTKEWLDEEWYKGLAIVNFIGLGMIILVGIMGLRTKISKRKLWDCGGNYGGADI
AIPSDGISDPLFPSLGRYFTNVEGNSRLDEGILQGIIKFLNMFKTKPNETNEESISINLAFSSVTVVILLFVIIGLKLTE
GDLWKLFLNTLTR

Sequences:

>Translated_573_residues
MIVLSYLIVLMSLVAPFLAAKVLGKNFLEQDSVLFIALTLQAVLGFISSIYVYGYEHRKRTTVLLGYSVFFLSTGLCYLV
GKTLWLILFWELSTVNAFLLYQGGKWTPNSIKSFIALVVAGGVGAFCFTYWIYSPKSEFGNMFLVAGLLVKAAFFGFHFW
LPEAHSGSPAHASAAYSGILVNLPLILFHQLVAPWFGNTIYIKILIPLAGFGVLWAGLSSLFSRDAKKAIAYSTVENMNF
LFLCILLSALWKDSEVESLKVLSRSFSFLFILSLIHHSISKTFQFLSIGYLTKISGFSNVDQNTGIGRISGLPTSLLSLG
TISFLAIPGTTGFLSEATFVKLVAGVLEIPGQSAILILPLLILVSSGLVLGAAGHLRIFLGMVLSRPRTNWPEHKPSRSV
FYSIFFSGVLILIVSFGISAYALYHSPTKEWLDEEWYKGLAIVNFIGLGMIILVGIMGLRTKISKRKLWDCGGNYGGADI
AIPSDGISDPLFPSLGRYFTNVEGNSRLDEGILQGIIKFLNMFKTKPNETNEESISINLAFSSVTVVILLFVIIGLKLTE
GDLWKLFLNTLTR
>Mature_573_residues
MIVLSYLIVLMSLVAPFLAAKVLGKNFLEQDSVLFIALTLQAVLGFISSIYVYGYEHRKRTTVLLGYSVFFLSTGLCYLV
GKTLWLILFWELSTVNAFLLYQGGKWTPNSIKSFIALVVAGGVGAFCFTYWIYSPKSEFGNMFLVAGLLVKAAFFGFHFW
LPEAHSGSPAHASAAYSGILVNLPLILFHQLVAPWFGNTIYIKILIPLAGFGVLWAGLSSLFSRDAKKAIAYSTVENMNF
LFLCILLSALWKDSEVESLKVLSRSFSFLFILSLIHHSISKTFQFLSIGYLTKISGFSNVDQNTGIGRISGLPTSLLSLG
TISFLAIPGTTGFLSEATFVKLVAGVLEIPGQSAILILPLLILVSSGLVLGAAGHLRIFLGMVLSRPRTNWPEHKPSRSV
FYSIFFSGVLILIVSFGISAYALYHSPTKEWLDEEWYKGLAIVNFIGLGMIILVGIMGLRTKISKRKLWDCGGNYGGADI
AIPSDGISDPLFPSLGRYFTNVEGNSRLDEGILQGIIKFLNMFKTKPNETNEESISINLAFSSVTVVILLFVIIGLKLTE
GDLWKLFLNTLTR

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788831, Length=353, Percent_Identity=26.3456090651558, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022997
- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 62996; Mature: 62996

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLSYLIVLMSLVAPFLAAKVLGKNFLEQDSVLFIALTLQAVLGFISSIYVYGYEHRKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCC
TTVLLGYSVFFLSTGLCYLVGKTLWLILFWELSTVNAFLLYQGGKWTPNSIKSFIALVVA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHH
GGVGAFCFTYWIYSPKSEFGNMFLVAGLLVKAAFFGFHFWLPEAHSGSPAHASAAYSGIL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
VNLPLILFHQLVAPWFGNTIYIKILIPLAGFGVLWAGLSSLFSRDAKKAIAYSTVENMNF
HHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LFLCILLSALWKDSEVESLKVLSRSFSFLFILSLIHHSISKTFQFLSIGYLTKISGFSNV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DQNTGIGRISGLPTSLLSLGTISFLAIPGTTGFLSEATFVKLVAGVLEIPGQSAILILPL
CCCCCCCCCCCCHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LILVSSGLVLGAAGHLRIFLGMVLSRPRTNWPEHKPSRSVFYSIFFSGVLILIVSFGISA
HHHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHH
YALYHSPTKEWLDEEWYKGLAIVNFIGLGMIILVGIMGLRTKISKRKLWDCGGNYGGADI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
AIPSDGISDPLFPSLGRYFTNVEGNSRLDEGILQGIIKFLNMFKTKPNETNEESISINLA
EECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
FSSVTVVILLFVIIGLKLTEGDLWKLFLNTLTR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIVLSYLIVLMSLVAPFLAAKVLGKNFLEQDSVLFIALTLQAVLGFISSIYVYGYEHRKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCC
TTVLLGYSVFFLSTGLCYLVGKTLWLILFWELSTVNAFLLYQGGKWTPNSIKSFIALVVA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHH
GGVGAFCFTYWIYSPKSEFGNMFLVAGLLVKAAFFGFHFWLPEAHSGSPAHASAAYSGIL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
VNLPLILFHQLVAPWFGNTIYIKILIPLAGFGVLWAGLSSLFSRDAKKAIAYSTVENMNF
HHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LFLCILLSALWKDSEVESLKVLSRSFSFLFILSLIHHSISKTFQFLSIGYLTKISGFSNV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DQNTGIGRISGLPTSLLSLGTISFLAIPGTTGFLSEATFVKLVAGVLEIPGQSAILILPL
CCCCCCCCCCCCHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LILVSSGLVLGAAGHLRIFLGMVLSRPRTNWPEHKPSRSVFYSIFFSGVLILIVSFGISA
HHHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHH
YALYHSPTKEWLDEEWYKGLAIVNFIGLGMIILVGIMGLRTKISKRKLWDCGGNYGGADI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
AIPSDGISDPLFPSLGRYFTNVEGNSRLDEGILQGIIKFLNMFKTKPNETNEESISINLA
EECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
FSSVTVVILLFVIIGLKLTEGDLWKLFLNTLTR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7846157; 8905231 [H]