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The map label for this gene is yfhR [C]

Identifier: 45659215

GI number: 45659215

Start: 4165941

End: 4166762

Strand: Direct

Name: yfhR [C]

Synonym: LIC13398

Alternate gene names: 45659215

Gene position: 4165941-4166762 (Clockwise)

Preceding gene: 45659214

Following gene: 45659223

Centisome position: 97.4

GC content: 31.02

Gene sequence:

>822_bases
ATGAAACGATCCATGAGCTTTATTATTACATTTTTATTATCTTTTATTTTTTTAATTTTATTTCTAATTTGGTGGAATCA
AGAAAGGCTGATTTTTTTTCCAGAAAAACTTTCTGAAAATTTTATATTCCATTTTCCGAATGAATTCAAAGAAATCAAAC
TGACCACTCCTGATGGAGAAAAGAGTTACGGACTTTTTTTTCCGTCTAAGAATAACCTTTCTAAAAAAACGATACTATTT
TTTCATGGGAACGCTGGAAGTTTGAGAACATGGGGAAGAATTTACGAAGACTTTCTTCCAATTGGATGGAACCTTTTAAT
TACGGATTACAGAGGATATGGAAAAAATTCCGGAAGTATTTCCGAAGAATCTATGAATTCGGACGCAGAATTATGGCTGA
GTTATTTGCTCAATGAGATTAAAATTCCCAGAAATGAAATTGTAATTTATGGCCGATCGATAGGAACAGGAGTAGCAATT
GATTTAGTTTCTAAAAATCCAGATTTAAATCTATTTTTAGAAACTCCGTTTATAGATCTATTTACATTAGCACGAAATTA
TTATCCCTTTATACAAGCTTGGATGTTAAAATTTCAATTTCAGAATCTGGCTAAACTAAAAAATATCCGTTCTAAAATCA
GAATATTTCACGGAACACAAGATCCAATTATTCCCTATTCCAATTCGGAAATCATATTCAAAAAACTGAAAGAACAAAAT
CAAGATGTAATTCTTTTTACGATTTCAAACGGTTCCCACAACGATCTTACTATTTATCCGGAATACCACCGCGCTTTGAA
AAATAGCCTGGATGAATTATAA

Upstream 100 bases:

>100_bases
AAGTGGAAAACGGAATGAAAGAAAACTAGTTCTACAGATTTTTGACGTTTATGGAAAAGAACTTTGGAAAAAAGAAATCC
TTTCAAATCCTTGATTTAGT

Downstream 100 bases:

>100_bases
CTTACATAAATGTTAATTAGAACTTGTTTTAGAATTATATCAAAACCTAAAGATTAACAAAGATTTTATAATAGAATACT
TTTTTTCTAATGTGGAAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKRSMSFIITFLLSFIFLILFLIWWNQERLIFFPEKLSENFIFHFPNEFKEIKLTTPDGEKSYGLFFPSKNNLSKKTILF
FHGNAGSLRTWGRIYEDFLPIGWNLLITDYRGYGKNSGSISEESMNSDAELWLSYLLNEIKIPRNEIVIYGRSIGTGVAI
DLVSKNPDLNLFLETPFIDLFTLARNYYPFIQAWMLKFQFQNLAKLKNIRSKIRIFHGTQDPIIPYSNSEIIFKKLKEQN
QDVILFTISNGSHNDLTIYPEYHRALKNSLDEL

Sequences:

>Translated_273_residues
MKRSMSFIITFLLSFIFLILFLIWWNQERLIFFPEKLSENFIFHFPNEFKEIKLTTPDGEKSYGLFFPSKNNLSKKTILF
FHGNAGSLRTWGRIYEDFLPIGWNLLITDYRGYGKNSGSISEESMNSDAELWLSYLLNEIKIPRNEIVIYGRSIGTGVAI
DLVSKNPDLNLFLETPFIDLFTLARNYYPFIQAWMLKFQFQNLAKLKNIRSKIRIFHGTQDPIIPYSNSEIIFKKLKEQN
QDVILFTISNGSHNDLTIYPEYHRALKNSLDEL
>Mature_273_residues
MKRSMSFIITFLLSFIFLILFLIWWNQERLIFFPEKLSENFIFHFPNEFKEIKLTTPDGEKSYGLFFPSKNNLSKKTILF
FHGNAGSLRTWGRIYEDFLPIGWNLLITDYRGYGKNSGSISEESMNSDAELWLSYLLNEIKIPRNEIVIYGRSIGTGVAI
DLVSKNPDLNLFLETPFIDLFTLARNYYPFIQAWMLKFQFQNLAKLKNIRSKIRIFHGTQDPIIPYSNSEIIFKKLKEQN
QDVILFTISNGSHNDLTIYPEYHRALKNSLDEL

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI71051602, Length=218, Percent_Identity=29.3577981651376, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI71051600, Length=218, Percent_Identity=29.3577981651376, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194306562, Length=199, Percent_Identity=28.643216080402, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI194306564, Length=199, Percent_Identity=28.1407035175879, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI49355781, Length=264, Percent_Identity=28.030303030303, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI151301175, Length=209, Percent_Identity=26.7942583732057, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI109689718, Length=175, Percent_Identity=29.7142857142857, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI24308097, Length=175, Percent_Identity=29.7142857142857, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI226510965, Length=267, Percent_Identity=22.0973782771536, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71988362, Length=198, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17566318, Length=215, Percent_Identity=23.7209302325581, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71985392, Length=160, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324009, Length=210, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281362521, Length=207, Percent_Identity=29.4685990338164, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281362519, Length=207, Percent_Identity=29.4685990338164, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28571878, Length=207, Percent_Identity=29.4685990338164, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17137566, Length=317, Percent_Identity=22.7129337539432, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 32070; Mature: 32070

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSMSFIITFLLSFIFLILFLIWWNQERLIFFPEKLSENFIFHFPNEFKEIKLTTPDGE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEEEECCCCCEEEEEECCCCC
KSYGLFFPSKNNLSKKTILFFHGNAGSLRTWGRIYEDFLPIGWNLLITDYRGYGKNSGSI
CCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
SEESMNSDAELWLSYLLNEIKIPRNEIVIYGRSIGTGVAIDLVSKNPDLNLFLETPFIDL
CHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCHHHH
FTLARNYYPFIQAWMLKFQFQNLAKLKNIRSKIRIFHGTQDPIIPYSNSEIIFKKLKEQN
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHCC
QDVILFTISNGSHNDLTIYPEYHRALKNSLDEL
CCEEEEEECCCCCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRSMSFIITFLLSFIFLILFLIWWNQERLIFFPEKLSENFIFHFPNEFKEIKLTTPDGE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEEEECCCCCEEEEEECCCCC
KSYGLFFPSKNNLSKKTILFFHGNAGSLRTWGRIYEDFLPIGWNLLITDYRGYGKNSGSI
CCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
SEESMNSDAELWLSYLLNEIKIPRNEIVIYGRSIGTGVAIDLVSKNPDLNLFLETPFIDL
CHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCHHHH
FTLARNYYPFIQAWMLKFQFQNLAKLKNIRSKIRIFHGTQDPIIPYSNSEIIFKKLKEQN
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHCC
QDVILFTISNGSHNDLTIYPEYHRALKNSLDEL
CCEEEEEECCCCCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]