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The map label for this gene is 45659185

Identifier: 45659185

GI number: 45659185

Start: 4128459

End: 4129535

Strand: Direct

Name: 45659185

Synonym: LIC13366

Alternate gene names: NA

Gene position: 4128459-4129535 (Clockwise)

Preceding gene: 45659184

Following gene: 45659193

Centisome position: 96.52

GC content: 34.45

Gene sequence:

>1077_bases
ATGTTTAAAAGAATTGTAATATTCCTTTTTATTCTTATTTTTCTTTCTTTATCCTTCTTGATTTTTTTATTTTTACGTTC
AAGTAAGAATACAAATGAATCTATCACGGATTCTCCTTTTGATCCTGGAAAAAATAATTATCTTTTAGAATCGGAATGGA
TTCATAAGGAAAATTTAAACCAACCTTACGCAATCGCTATAGACGCTCGCGGTTATGTCTATACTGGAACCGCAGATCAT
AAAGTCGTACAAATCCGTACTAACGAAAAAATAGAAACCTTCGCCGTTCTTTCAGGAAGGCCTTTAGGAATGGTATTTGA
TTCTCACGGAAATCTTTTGGTTTGTGTAGAAGAAGTTGGAATCGTAAAAATTCGTAAAGACGGATCACAAAAAACTATTA
TCTCTAAACTTCCGGACGGTTCACCTCTTCGATTTCCACATGGAATTGACATTTCTAAAGACGGAAAAATATATTTCACC
GTTTCCAGCCAATCGTATTCATTACAAGAATCTTTTTTAGAAGAACTTTTTTCTCGCCCAAACGGAATGATAGTAACAGC
GGATAAAAATCTTACATTAGAAATTTTGAATCAAGATTTGTATTATCCTACTGGAATCGCATTGTCATCTAACGAAGAAT
TTTTACTCGTATCGGAACCATTTCGACATAGAATTTCCTCGATTCCGATATTCGGTTCCCAAAGAGGTACGGAGAAATTT
TTTCTTACGAATATTCCCGGAATTCCCGCTTTGATCAGTGGGAACGGAGGTTTTTTCTGGGTCGGAATTCCATATCATAG
AAATGAAATTTTAGATAAAACCCAAGAATATCCCGAAATTAAAAACCTACTGACAGGTTTACCTGTTTTTCTTTTTGGAA
AAAATATTCCGAGAGGTTTGGTATTTGCTTTAAATGATTTTGGAGATATTACGGCCAATTACCAAGATTTTTCGGATTCT
TCGGTTGCAGGTATTACCGCAGTTTTAAACCACGCCGGAAATATTTATTTGGTATCTTCGACCATCGGAAAAATCGCAAA
GATGAAACCGATAATCGAAGAAATTCAATTTTTCTAA

Upstream 100 bases:

>100_bases
AAGATCGGAGAAGTCGGTCAAACCGGAAGAGCCACCGGAAATCATTTACACTTCGAGGTTAGAAGATTCAACCAAAGACA
AAAACCGATTTTTAGAGACC

Downstream 100 bases:

>100_bases
TATTAGATTTTACATAGATCCAAGCGCTTCTCTAAATCTTTCAAGAGGGAATCTATTTACAAAATCTCCGAATTTTTCGT
CGGAATCCCCTTCGTTTTTC

Product: putative strictosidine synthase

Products: tryptamine; secologanin

Alternate protein names: Strictosidine Synthase Family Protein; Gluconolactonase; Inner-Membrane Translocator; ABC Transporter Permease Protein; Strictosidine Synthase Conserved Region; Permease Protein Of Sugar ABC Transporter; ABC Transporter; SMP-30/Gluconolaconase/LRE Domain Protein; Strictosidine Synthase Subfamily

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MFKRIVIFLFILIFLSLSFLIFLFLRSSKNTNESITDSPFDPGKNNYLLESEWIHKENLNQPYAIAIDARGYVYTGTADH
KVVQIRTNEKIETFAVLSGRPLGMVFDSHGNLLVCVEEVGIVKIRKDGSQKTIISKLPDGSPLRFPHGIDISKDGKIYFT
VSSQSYSLQESFLEELFSRPNGMIVTADKNLTLEILNQDLYYPTGIALSSNEEFLLVSEPFRHRISSIPIFGSQRGTEKF
FLTNIPGIPALISGNGGFFWVGIPYHRNEILDKTQEYPEIKNLLTGLPVFLFGKNIPRGLVFALNDFGDITANYQDFSDS
SVAGITAVLNHAGNIYLVSSTIGKIAKMKPIIEEIQFF

Sequences:

>Translated_358_residues
MFKRIVIFLFILIFLSLSFLIFLFLRSSKNTNESITDSPFDPGKNNYLLESEWIHKENLNQPYAIAIDARGYVYTGTADH
KVVQIRTNEKIETFAVLSGRPLGMVFDSHGNLLVCVEEVGIVKIRKDGSQKTIISKLPDGSPLRFPHGIDISKDGKIYFT
VSSQSYSLQESFLEELFSRPNGMIVTADKNLTLEILNQDLYYPTGIALSSNEEFLLVSEPFRHRISSIPIFGSQRGTEKF
FLTNIPGIPALISGNGGFFWVGIPYHRNEILDKTQEYPEIKNLLTGLPVFLFGKNIPRGLVFALNDFGDITANYQDFSDS
SVAGITAVLNHAGNIYLVSSTIGKIAKMKPIIEEIQFF
>Mature_358_residues
MFKRIVIFLFILIFLSLSFLIFLFLRSSKNTNESITDSPFDPGKNNYLLESEWIHKENLNQPYAIAIDARGYVYTGTADH
KVVQIRTNEKIETFAVLSGRPLGMVFDSHGNLLVCVEEVGIVKIRKDGSQKTIISKLPDGSPLRFPHGIDISKDGKIYFT
VSSQSYSLQESFLEELFSRPNGMIVTADKNLTLEILNQDLYYPTGIALSSNEEFLLVSEPFRHRISSIPIFGSQRGTEKF
FLTNIPGIPALISGNGGFFWVGIPYHRNEILDKTQEYPEIKNLLTGLPVFLFGKNIPRGLVFALNDFGDITANYQDFSDS
SVAGITAVLNHAGNIYLVSSTIGKIAKMKPIIEEIQFF

Specific function: Unknown

COG id: COG3386

COG function: function code G; Gluconolactonase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24308201, Length=365, Percent_Identity=29.041095890411, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17534469, Length=373, Percent_Identity=24.3967828418231, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193207213, Length=327, Percent_Identity=23.5474006116208, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17542364, Length=281, Percent_Identity=25.6227758007117, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17137194, Length=309, Percent_Identity=23.9482200647249, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24650914, Length=404, Percent_Identity=22.5247524752475, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.3.3.2

Molecular weight: Translated: 40169; Mature: 40169

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRIVIFLFILIFLSLSFLIFLFLRSSKNTNESITDSPFDPGKNNYLLESEWIHKENLN
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCC
QPYAIAIDARGYVYTGTADHKVVQIRTNEKIETFAVLSGRPLGMVFDSHGNLLVCVEEVG
CCEEEEEECCCEEEECCCCCEEEEEECCCCEEEEEEECCCCEEEEEECCCCEEEEEECCC
IVKIRKDGSQKTIISKLPDGSPLRFPHGIDISKDGKIYFTVSSQSYSLQESFLEELFSRP
EEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
NGMIVTADKNLTLEILNQDLYYPTGIALSSNEEFLLVSEPFRHRISSIPIFGSQRGTEKF
CCEEEEECCCCEEEEECCCCCCCCCEEECCCCCEEEECCHHHHHHHCCCEECCCCCCCEE
FLTNIPGIPALISGNGGFFWVGIPYHRNEILDKTQEYPEIKNLLTGLPVFLFGKNIPRGL
EEECCCCCCEEEECCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCE
VFALNDFGDITANYQDFSDSSVAGITAVLNHAGNIYLVSSTIGKIAKMKPIIEEIQFF
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKRIVIFLFILIFLSLSFLIFLFLRSSKNTNESITDSPFDPGKNNYLLESEWIHKENLN
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCC
QPYAIAIDARGYVYTGTADHKVVQIRTNEKIETFAVLSGRPLGMVFDSHGNLLVCVEEVG
CCEEEEEECCCEEEECCCCCEEEEEECCCCEEEEEEECCCCEEEEEECCCCEEEEEECCC
IVKIRKDGSQKTIISKLPDGSPLRFPHGIDISKDGKIYFTVSSQSYSLQESFLEELFSRP
EEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCC
NGMIVTADKNLTLEILNQDLYYPTGIALSSNEEFLLVSEPFRHRISSIPIFGSQRGTEKF
CCEEEEECCCCEEEEECCCCCCCCCEEECCCCCEEEECCHHHHHHHCCCEECCCCCCCEE
FLTNIPGIPALISGNGGFFWVGIPYHRNEILDKTQEYPEIKNLLTGLPVFLFGKNIPRGL
EEECCCCCCEEEECCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCE
VFALNDFGDITANYQDFSDSSVAGITAVLNHAGNIYLVSSTIGKIAKMKPIIEEIQFF
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-alpha(S)-strictosidine

Specific reaction: 3-alpha(S)-strictosidine = tryptamine + secologanin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA