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The map label for this gene is gpmB

Identifier: 45659177

GI number: 45659177

Start: 4116050

End: 4116634

Strand: Direct

Name: gpmB

Synonym: LIC13358

Alternate gene names: 45659177

Gene position: 4116050-4116634 (Clockwise)

Preceding gene: 45659176

Following gene: 45659178

Centisome position: 96.23

GC content: 30.77

Gene sequence:

>585_bases
ATGGAACTCTATTTAATCCGACATACTACTCCAGAAATTCCAAAAGGAATCTGTTACGGTCAAACGGACATACCTTTAAT
TTCCGACTTTAATTCAGAATTTCAATTCCTTCTTCAAAAAATCAACGTTGTTTTTGATCTAATTTATTCTAGTCCGAGCA
GTCGTTGCAGAAAATTATCTGAATTTTTGAATAATCAATATTTAAGTAAACTAGAATATTCAGATTTATTGATGGAATTG
AATTTTGGATCATGGGAAGGAAAACCTTGGTTAGAAATTCCAAAAAAAGAATACTCTTATTGGGCAAAAGATTTTGTAAA
CTTTAAAGTTCCCAACGGAGAAAGTTATCAAGGGTTATACGAAAGGGTTTCTAAATTTTTAGATAAAATTTTACATTCTT
TTTCGGATGAAAAAATCGGAATCGTCACCCACGCAGGAGTCATTAGAACCGCTCTTTGTAAACTTTTAAATATACCACTA
GAACGCGGATTTTATTTCGATCTGAACTATGGCTCTATAAACAAAATTCTCATAGAAAAAGATGGAAAAGATTTTTTTTC
CAAATTAATCTTCTGGAATCTTTAA

Upstream 100 bases:

>100_bases
GAAATTATTTTAATAAATGGATTGAGGGTTTTACGGGAGATTGTCTTGGGTTTATCCAACAAGGAACTGAACTTTTATTC
TATTTAGGAATTACAGTTTC

Downstream 100 bases:

>100_bases
GTTGGTTATAGTTTTTTTCGAATTGCCGATACAACTCTTAGAGCCCGGTCCATAAAACTTTAAAGGCTCCTTACATAACT
TATCAAAAAAACATATGATA

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MELYLIRHTTPEIPKGICYGQTDIPLISDFNSEFQFLLQKINVVFDLIYSSPSSRCRKLSEFLNNQYLSKLEYSDLLMEL
NFGSWEGKPWLEIPKKEYSYWAKDFVNFKVPNGESYQGLYERVSKFLDKILHSFSDEKIGIVTHAGVIRTALCKLLNIPL
ERGFYFDLNYGSINKILIEKDGKDFFSKLIFWNL

Sequences:

>Translated_194_residues
MELYLIRHTTPEIPKGICYGQTDIPLISDFNSEFQFLLQKINVVFDLIYSSPSSRCRKLSEFLNNQYLSKLEYSDLLMEL
NFGSWEGKPWLEIPKKEYSYWAKDFVNFKVPNGESYQGLYERVSKFLDKILHSFSDEKIGIVTHAGVIRTALCKLLNIPL
ERGFYFDLNYGSINKILIEKDGKDFFSKLIFWNL
>Mature_194_residues
MELYLIRHTTPEIPKGICYGQTDIPLISDFNSEFQFLLQKINVVFDLIYSSPSSRCRKLSEFLNNQYLSKLEYSDLLMEL
NFGSWEGKPWLEIPKKEYSYWAKDFVNFKVPNGESYQGLYERVSKFLDKILHSFSDEKIGIVTHAGVIRTALCKLLNIPL
ERGFYFDLNYGSINKILIEKDGKDFFSKLIFWNL

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=185, Percent_Identity=25.4054054054054, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 22769; Mature: 22769

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYLIRHTTPEIPKGICYGQTDIPLISDFNSEFQFLLQKINVVFDLIYSSPSSRCRKLS
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFLNNQYLSKLEYSDLLMELNFGSWEGKPWLEIPKKEYSYWAKDFVNFKVPNGESYQGLY
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHH
ERVSKFLDKILHSFSDEKIGIVTHAGVIRTALCKLLNIPLERGFYFDLNYGSINKILIEK
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCHHHCCEEEEECCCCEEEEEEEC
DGKDFFSKLIFWNL
CCHHHHHHHHHCCC
>Mature Secondary Structure
MELYLIRHTTPEIPKGICYGQTDIPLISDFNSEFQFLLQKINVVFDLIYSSPSSRCRKLS
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFLNNQYLSKLEYSDLLMELNFGSWEGKPWLEIPKKEYSYWAKDFVNFKVPNGESYQGLY
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHH
ERVSKFLDKILHSFSDEKIGIVTHAGVIRTALCKLLNIPLERGFYFDLNYGSINKILIEK
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCHHHCCEEEEECCCCEEEEEEEC
DGKDFFSKLIFWNL
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]