BacMap

Definition	Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence.
Accession	NC_005823
Length	4,277,185

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The map label for this gene is copA [H]

Identifier: 45658809

GI number: 45658809

Start: 3620274

End: 3622493

Strand: Reverse

Name: copA [H]

Synonym: LIC12982

Alternate gene names: 45658809

Gene position: 3622493-3620274 (Counterclockwise)

Preceding gene: 45658810

Following gene: 45658806

Centisome position: 84.69

GC content: 37.12

Gene sequence:

>2220_bases
ATGAAAGTTCAACAAGAATTGCATTTAAATGAAGTAACATTAGACGTAATTGGAATGACCTGTGCCAATTGTGCACTTAG
AATTGAAAAAGGACTTAAAAAAATACCAGGAGTTAAGGATGTAAGAGTTAATTTTGCAATGGAAACCGCAAAGATAGATT
TTGAATCTTCAATCTCAAAAGAAATTCTAATGGATAAAATAGATTTTTTAGGTTATCGTGCGGTTGTTCACGAAGATATA
GAAATAGATGGAGAAATTCAGAAAAAAGAATTCAAAAAACTAAAAGTTCGAGTTATTGTTTCCGCATTTTTGTCTTTACC
ATTACTTTTAAGTATGATTGGGCATTTTGAGAATAATCTAAATTTTGAATATTTATCTTTTCTAATGAATCCTTGGTTAC
AGTTTGTTTTAGCTACCCCAATCCAATTTTGGATCGGAGCTTCTTTTTATAAAGGTAGTTTTCGCGCTCTTAGAAATGGG
GGAGCTAATATGGACGTTCTAGTTGTTTTAGGAACGTCTGCCGCGTATTTTTATAGCGTCTATTTGACATTTATTTTCAA
TGAAAAATACATTCATAAGACAGCGAATCTATATTACGAAACTTCATCTGTGTTGATCACTTTGATTCTTTTTGGAAAAT
TGTTGGAACATATAGTAAAGGGTAAATCTTCGAAGGCAATTCAATCCTTGGTAAATTTACAACCAAAAAAAGCGAACGTC
ATTAGAGAAAAAGAGATTCAAGAGATCCCTTTGCTTGCAGTTCGCTCTGGAGATTTGATTTTGGTAAAGCCGGGAGAAAG
TATTCCTGTGGACGGAATAATAGAAGAGGGAAGTTCAACCATCGACGAATCGATGTTAACCGGAGAAAGCATTCCTGTTG
AAAAAACAATTTCCAATTTCGTTTACGGAGGTTCATTAAATCAAAACGGAACTTTCAAGTTCAGGGCTTTAAAAGTTGGA
AAAGAAACTTTGCTCTCGGGAATCATTCGAGCGGTTCGAGAAGCCCAAGGAACCAAGGCTCCGATTCAAAGGATTGCAGA
TCAAATTTCGGAAATATTTGTTCCAGTGATTGTTTTGATCTCAGTAATTACTTTATGTGTATGGTATTTTTGGATTTTGC
CTTCTACCTTTTCAGTAGCACTAGAAAAGGCAATTGCTGTGCTTGTGGTCGCTTGTCCTTGTGCTTTAGGTTTGGCGACT
CCGATTTCGGTTTTAACCGGGTCTGGAAAAGCGGCTACTATGGGAATTTTGTTTCGTAGTGCAGAAGCATTAGAAATATT
GCATAAAGTAAATGCAATTGTTTTTGATAAGACCGGGACTTTAACTTATGGAAAACCGGTTTTGAAAAGTTTAGAAAGTT
TGAATATGACTAAAGAAAATAATTTACTTACGTTAGCCGCTTCTGCTGAACAGAACTCGGAACATCCTCTTTCGAAAGCG
ATCGTAGAAAGTGCAAAGAAAAAAGGTCTTGTTTTAGCGATTCCCGAAAATTTTGAAACAATACCTGGAGGAGGTATTTC
CGCCATTGTGGAGGGAAATCGGATATTGATTGGAACAGAGAGATTATTTTACGCAAAAGGAATAGAGCTGAATCAAGAAT
TAAACAATCTGAAACGAATAAGAGAAGAAGAAGGAAATACGGTCGTCCATTTGAGTGTGAACGGAATTCATTCTGCTATA
TTGACATTAGCAGATACGCTTAAAGAATCTACTCCGGCAACGATCGAAAAGTTGAAATCTTTGGGTATAGAAGTTTATAT
GATAACTGGAGACAATGAAAGAACGGCTCGAGTTATCTCAAAAGATTGTGGTATTGAACGCGTGTTAGCTGAAGTTCTTC
CGGAGAAAAAAGCGATGGAAGTAAAGAATCTAAAAAGTTTAGGAAAAGTGGTTTCTATGGTGGGGGACGGAATTAACGAT
GCTCCTGCGCTTGCGATTTCGGATCTTGGGATTGCTATGGGAACCGGAACGGATGTGGCAATGGAATCTTCCGATTTAGT
GATCGTAAACGGGGATTTGAATTCAATTGTAAACGCTATTACTATCAGCAGAAAAACGGTTTATAATATTCGACAGAATT
TTTTCTGGGCGCTACTCTATAATACGTTAGGTATTCCGATCGCAGCCGCAGGATTTTTAGCACCTTGGGTTGCGGGTGGG
GCTATGGCTCTCAGTTCGGTTTCGGTAGTTTTAAACGCCCTTAGATTACAAAGGGATTGA

Upstream 100 bases:

>100_bases
CAAACTTAGAAAATCGGGAAGTCGTTTATTACGGAAAAGGAACTACAGAAGAATTATCGAAGGTTAAAGAAACTATTTTA
AAAAAAGGTTATAAACCAGG

Downstream 100 bases:

>100_bases
TTTTCAATAAATTAGTAATTTAATATATTAAAATGTTTTATTTTCATAGAAAAAATACATAAAAAAATAATAATATGATG
TAAATTTGCTTTAAGTGAAC

Product: heavy-metal transporting p-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: Protein CopA [H]

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MKVQQELHLNEVTLDVIGMTCANCALRIEKGLKKIPGVKDVRVNFAMETAKIDFESSISKEILMDKIDFLGYRAVVHEDI
EIDGEIQKKEFKKLKVRVIVSAFLSLPLLLSMIGHFENNLNFEYLSFLMNPWLQFVLATPIQFWIGASFYKGSFRALRNG
GANMDVLVVLGTSAAYFYSVYLTFIFNEKYIHKTANLYYETSSVLITLILFGKLLEHIVKGKSSKAIQSLVNLQPKKANV
IREKEIQEIPLLAVRSGDLILVKPGESIPVDGIIEEGSSTIDESMLTGESIPVEKTISNFVYGGSLNQNGTFKFRALKVG
KETLLSGIIRAVREAQGTKAPIQRIADQISEIFVPVIVLISVITLCVWYFWILPSTFSVALEKAIAVLVVACPCALGLAT
PISVLTGSGKAATMGILFRSAEALEILHKVNAIVFDKTGTLTYGKPVLKSLESLNMTKENNLLTLAASAEQNSEHPLSKA
IVESAKKKGLVLAIPENFETIPGGGISAIVEGNRILIGTERLFYAKGIELNQELNNLKRIREEEGNTVVHLSVNGIHSAI
LTLADTLKESTPATIEKLKSLGIEVYMITGDNERTARVISKDCGIERVLAEVLPEKKAMEVKNLKSLGKVVSMVGDGIND
APALAISDLGIAMGTGTDVAMESSDLVIVNGDLNSIVNAITISRKTVYNIRQNFFWALLYNTLGIPIAAAGFLAPWVAGG
AMALSSVSVVLNALRLQRD

Sequences:

>Translated_739_residues
MKVQQELHLNEVTLDVIGMTCANCALRIEKGLKKIPGVKDVRVNFAMETAKIDFESSISKEILMDKIDFLGYRAVVHEDI
EIDGEIQKKEFKKLKVRVIVSAFLSLPLLLSMIGHFENNLNFEYLSFLMNPWLQFVLATPIQFWIGASFYKGSFRALRNG
GANMDVLVVLGTSAAYFYSVYLTFIFNEKYIHKTANLYYETSSVLITLILFGKLLEHIVKGKSSKAIQSLVNLQPKKANV
IREKEIQEIPLLAVRSGDLILVKPGESIPVDGIIEEGSSTIDESMLTGESIPVEKTISNFVYGGSLNQNGTFKFRALKVG
KETLLSGIIRAVREAQGTKAPIQRIADQISEIFVPVIVLISVITLCVWYFWILPSTFSVALEKAIAVLVVACPCALGLAT
PISVLTGSGKAATMGILFRSAEALEILHKVNAIVFDKTGTLTYGKPVLKSLESLNMTKENNLLTLAASAEQNSEHPLSKA
IVESAKKKGLVLAIPENFETIPGGGISAIVEGNRILIGTERLFYAKGIELNQELNNLKRIREEEGNTVVHLSVNGIHSAI
LTLADTLKESTPATIEKLKSLGIEVYMITGDNERTARVISKDCGIERVLAEVLPEKKAMEVKNLKSLGKVVSMVGDGIND
APALAISDLGIAMGTGTDVAMESSDLVIVNGDLNSIVNAITISRKTVYNIRQNFFWALLYNTLGIPIAAAGFLAPWVAGG
AMALSSVSVVLNALRLQRD
>Mature_739_residues
MKVQQELHLNEVTLDVIGMTCANCALRIEKGLKKIPGVKDVRVNFAMETAKIDFESSISKEILMDKIDFLGYRAVVHEDI
EIDGEIQKKEFKKLKVRVIVSAFLSLPLLLSMIGHFENNLNFEYLSFLMNPWLQFVLATPIQFWIGASFYKGSFRALRNG
GANMDVLVVLGTSAAYFYSVYLTFIFNEKYIHKTANLYYETSSVLITLILFGKLLEHIVKGKSSKAIQSLVNLQPKKANV
IREKEIQEIPLLAVRSGDLILVKPGESIPVDGIIEEGSSTIDESMLTGESIPVEKTISNFVYGGSLNQNGTFKFRALKVG
KETLLSGIIRAVREAQGTKAPIQRIADQISEIFVPVIVLISVITLCVWYFWILPSTFSVALEKAIAVLVVACPCALGLAT
PISVLTGSGKAATMGILFRSAEALEILHKVNAIVFDKTGTLTYGKPVLKSLESLNMTKENNLLTLAASAEQNSEHPLSKA
IVESAKKKGLVLAIPENFETIPGGGISAIVEGNRILIGTERLFYAKGIELNQELNNLKRIREEEGNTVVHLSVNGIHSAI
LTLADTLKESTPATIEKLKSLGIEVYMITGDNERTARVISKDCGIERVLAEVLPEKKAMEVKNLKSLGKVVSMVGDGIND
APALAISDLGIAMGTGTDVAMESSDLVIVNGDLNSIVNAITISRKTVYNIRQNFFWALLYNTLGIPIAAAGFLAPWVAGG
AMALSSVSVVLNALRLQRD

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=825, Percent_Identity=36.6060606060606, Blast_Score=485, Evalue=1e-137,
Organism=Homo sapiens, GI55743071, Length=796, Percent_Identity=33.9195979899498, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI55743073, Length=822, Percent_Identity=30.0486618004866, Blast_Score=345, Evalue=9e-95,
Organism=Homo sapiens, GI28373113, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373105, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373103, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373109, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373107, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373115, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373111, Length=171, Percent_Identity=32.7485380116959, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI209413709, Length=203, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI24638454, Length=203, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI4502285, Length=203, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI153946397, Length=214, Percent_Identity=26.1682242990654, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI10835220, Length=177, Percent_Identity=31.0734463276836, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI27886529, Length=177, Percent_Identity=31.0734463276836, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI310128958, Length=173, Percent_Identity=31.2138728323699, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI4502271, Length=197, Percent_Identity=25.3807106598985, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI48762689, Length=141, Percent_Identity=34.7517730496454, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI48762687, Length=141, Percent_Identity=34.7517730496454, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI48762685, Length=141, Percent_Identity=34.7517730496454, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI48762691, Length=141, Percent_Identity=34.7517730496454, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI118498343, Length=148, Percent_Identity=34.4594594594595, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI21361181, Length=269, Percent_Identity=29.368029739777, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI22748667, Length=197, Percent_Identity=24.8730964467005, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI237681109, Length=197, Percent_Identity=24.8730964467005, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI237681111, Length=269, Percent_Identity=29.368029739777, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI51944966, Length=198, Percent_Identity=24.2424242424242, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI66932949, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI83700225, Length=291, Percent_Identity=24.3986254295533, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1786691, Length=745, Percent_Identity=39.3288590604027, Blast_Score=490, Evalue=1e-139,
Organism=Escherichia coli, GI1789879, Length=739, Percent_Identity=31.2584573748309, Blast_Score=308, Evalue=8e-85,
Organism=Escherichia coli, GI1786914, Length=508, Percent_Identity=28.1496062992126, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI2367363, Length=597, Percent_Identity=23.2830820770519, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17556548, Length=787, Percent_Identity=34.1804320203304, Blast_Score=390, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17541776, Length=220, Percent_Identity=32.2727272727273, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71999440, Length=174, Percent_Identity=33.9080459770115, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17557486, Length=191, Percent_Identity=29.8429319371728, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25152707, Length=174, Percent_Identity=33.9080459770115, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71988506, Length=177, Percent_Identity=30.5084745762712, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999438, Length=174, Percent_Identity=33.9080459770115, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554158, Length=177, Percent_Identity=30.5084745762712, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193210130, Length=177, Percent_Identity=30.5084745762712, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566766, Length=191, Percent_Identity=29.8429319371728, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557770, Length=191, Percent_Identity=29.8429319371728, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559224, Length=226, Percent_Identity=25.6637168141593, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997262, Length=197, Percent_Identity=31.9796954314721, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71997275, Length=197, Percent_Identity=31.9796954314721, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71997269, Length=164, Percent_Identity=32.3170731707317, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531459, Length=95, Percent_Identity=38.9473684210526, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203354, Length=291, Percent_Identity=25.4295532646048, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203356, Length=291, Percent_Identity=25.4295532646048, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=753, Percent_Identity=36.6533864541833, Blast_Score=402, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6319772, Length=683, Percent_Identity=32.2108345534407, Blast_Score=307, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6321430, Length=542, Percent_Identity=25.0922509225092, Blast_Score=133, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6325221, Length=577, Percent_Identity=24.263431542461, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321432, Length=183, Percent_Identity=32.2404371584699, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321271, Length=168, Percent_Identity=35.1190476190476, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320245, Length=241, Percent_Identity=28.6307053941909, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320243, Length=241, Percent_Identity=28.6307053941909, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320244, Length=241, Percent_Identity=28.6307053941909, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221329854, Length=858, Percent_Identity=34.032634032634, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24668708, Length=586, Percent_Identity=24.7440273037543, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI281366617, Length=586, Percent_Identity=24.7440273037543, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24668704, Length=586, Percent_Identity=24.7440273037543, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24668696, Length=586, Percent_Identity=24.7440273037543, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI161085803, Length=586, Percent_Identity=24.7440273037543, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24762455, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762453, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762447, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762457, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762449, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762445, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762451, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17136664, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281359543, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359537, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359539, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359545, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359541, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359535, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648582, Length=226, Percent_Identity=24.7787610619469, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362164, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553441, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648580, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648578, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553437, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553435, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553439, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648576, Length=197, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281366676, Length=195, Percent_Identity=25.1282051282051, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR006122
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 80620; Mature: 80620

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVQQELHLNEVTLDVIGMTCANCALRIEKGLKKIPGVKDVRVNFAMETAKIDFESSISK
CCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCHHHHHHH
EILMDKIDFLGYRAVVHEDIEIDGEIQKKEFKKLKVRVIVSAFLSLPLLLSMIGHFENNL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NFEYLSFLMNPWLQFVLATPIQFWIGASFYKGSFRALRNGGANMDVLVVLGTSAAYFYSV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCCCEEEEEEECCCHHHHHHH
YLTFIFNEKYIHKTANLYYETSSVLITLILFGKLLEHIVKGKSSKAIQSLVNLQPKKANV
HHHHHCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHH
IREKEIQEIPLLAVRSGDLILVKPGESIPVDGIIEEGSSTIDESMLTGESIPVEKTISNF
HHHHHHHHCCEEEEECCCEEEECCCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHH
VYGGSLNQNGTFKFRALKVGKETLLSGIIRAVREAQGTKAPIQRIADQISEIFVPVIVLI
EECCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SVITLCVWYFWILPSTFSVALEKAIAVLVVACPCALGLATPISVLTGSGKAATMGILFRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCHHHHHHHHHH
AEALEILHKVNAIVFDKTGTLTYGKPVLKSLESLNMTKENNLLTLAASAEQNSEHPLSKA
HHHHHHHHHHCEEEEECCCCEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHH
IVESAKKKGLVLAIPENFETIPGGGISAIVEGNRILIGTERLFYAKGIELNQELNNLKRI
HHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCEEEEECCCEEEECCCCHHHHHHHHHHH
REEEGNTVVHLSVNGIHSAILTLADTLKESTPATIEKLKSLGIEVYMITGDNERTARVIS
HHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHH
KDCGIERVLAEVLPEKKAMEVKNLKSLGKVVSMVGDGINDAPALAISDLGIAMGTGTDVA
HHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEECCCCCEE
MESSDLVIVNGDLNSIVNAITISRKTVYNIRQNFFWALLYNTLGIPIAAAGFLAPWVAGG
ECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCH
AMALSSVSVVLNALRLQRD
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVQQELHLNEVTLDVIGMTCANCALRIEKGLKKIPGVKDVRVNFAMETAKIDFESSISK
CCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCHHHHHHH
EILMDKIDFLGYRAVVHEDIEIDGEIQKKEFKKLKVRVIVSAFLSLPLLLSMIGHFENNL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NFEYLSFLMNPWLQFVLATPIQFWIGASFYKGSFRALRNGGANMDVLVVLGTSAAYFYSV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCCCEEEEEEECCCHHHHHHH
YLTFIFNEKYIHKTANLYYETSSVLITLILFGKLLEHIVKGKSSKAIQSLVNLQPKKANV
HHHHHCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHH
IREKEIQEIPLLAVRSGDLILVKPGESIPVDGIIEEGSSTIDESMLTGESIPVEKTISNF
HHHHHHHHCCEEEEECCCEEEECCCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHH
VYGGSLNQNGTFKFRALKVGKETLLSGIIRAVREAQGTKAPIQRIADQISEIFVPVIVLI
EECCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
SVITLCVWYFWILPSTFSVALEKAIAVLVVACPCALGLATPISVLTGSGKAATMGILFRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCHHHHHHHHHH
AEALEILHKVNAIVFDKTGTLTYGKPVLKSLESLNMTKENNLLTLAASAEQNSEHPLSKA
HHHHHHHHHHCEEEEECCCCEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHH
IVESAKKKGLVLAIPENFETIPGGGISAIVEGNRILIGTERLFYAKGIELNQELNNLKRI
HHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCEEEEECCCEEEECCCCHHHHHHHHHHH
REEEGNTVVHLSVNGIHSAILTLADTLKESTPATIEKLKSLGIEVYMITGDNERTARVIS
HHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHH
KDCGIERVLAEVLPEKKAMEVKNLKSLGKVVSMVGDGINDAPALAISDLGIAMGTGTDVA
HHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEECCCCCEE
MESSDLVIVNGDLNSIVNAITISRKTVYNIRQNFFWALLYNTLGIPIAAAGFLAPWVAGG
ECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCH
AMALSSVSVVLNALRLQRD
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12644235; 11922674; 12590580 [H]