Click here to switch to the map view.

The map label for this gene is aslA

Identifier: 45658714

GI number: 45658714

Start: 3482892

End: 3484490

Strand: Reverse

Name: aslA

Synonym: LIC12884

Alternate gene names: 45658714

Gene position: 3484490-3482892 (Counterclockwise)

Preceding gene: 45658715

Following gene: 45658713

Centisome position: 81.47

GC content: 37.15

Gene sequence:

>1599_bases
ATGTTGATCGGATCGATTTCCTTTTTATTTGCGGTTGTTTCTTTGTTGAACGCAAGATCTATAACTAAAACGGAAATTTC
ACCCGTTTTTTTAAATCTTCCTAACATTTTAATTCTGAGCGCGGATAGTCTGCGTTATGATAAAATGGGATATGCAGAAG
GCAAAGAAGGGATGACTCCTAATATAGATCTTCTATCTAAAGATTCTATAATATTCGAAGATCATCATACAACAATTCCT
CGGACCTTCCCGGCTTGGGCTGATTTGCTAACGGGGCAACCCAGTTTTATACATGGAATTCAGGATATGTTTCCGGATAA
AAAGGATCGGGAAGGACTTACTTTTAAAACACTTCCAAAACTATTGTCACAACTTGGATATAAAACGAACGTGGTATCTT
CGTTTGCAGGAGATATTTTTCCAAGAGCTGATTGGGGATTTCGATCGGTCCAGGCGCCTATTTTTCATGCAGGAACTCTT
ACTTCTCAAAGAATTTTAGAAACTCAAATCTTTCTACTTCCGATTGTGACTGGTTCTGTTCCGGGAGCGGGGGAATATTT
TCCAGCGATTCGAGGACTCCCTAGTTTGGGAGACGATTCTAAAATACTTCCGGATCTTTGGAACAGTTTTGAAAAAAATG
AAGAACCATTTTTTACCGTATTTTTTTCTTCGGTAACACATTTCCCTTTTAGTCCGCCGTACCCACATTATAAGAATTTT
ACAAATTCAGAATATTACGGAAAGTTTAAATATTTTAAATTTGTAGATCCGGGTGATTCTTCCGAACCTTCTTTAGAAGA
TAAGGAACAAATTCGAGGGCTTTTTCAAGCTTCGATTTATTCTTTTGACCAAACGGTCGGGAAGGTCGTCGAACGTCTGA
AAAAAAAAGGAATTTACGATTCCACTTTGATTGTTTTAACGAGCGATCATGGAGAATCCTTGTTTGAAGCGGATCATAAC
CACGGACATGGAGAACATTTAAGAGGAGAGGGTGTAACTCATATTCCTCTTTTGATTAAATTACCAAAAAATCTGGGAGC
CGGAATTCGATTTTCCGGAATCAGTAGTTCTTTAGATTTGTTCCCTACACTTTTAACTTTCGTATCGAAAGAAATCCAAG
ATCCTTCTATTAGAAATCAATTTTTGAAAGAACTTTCTAGTCGATCTGGAAGAGACCTTTCTTTTGCTTTGAATTCTACA
ACTTGGAAGGATTCTAGAAACGTATATGGAGAAACCGGAATCTGGTTCAGCGATTTGGGAGATCATTTCTTTCAAAAGGA
AAGAATTTTTTATCCTAGCATTCTTCATCTACATTCGATTGAATCAGGGGAGCTTCCTTTTATTTCGATCGGAGATTCTT
ACGCAAAGGAAAGTATCATCGTTTCCAAACATAGAATGTTTCAAAATTCTAACCGCAAATTGATTTATATTCCTTCCGAA
GACGGAGTGATTTGGCGTTGTTATGATAGGATCAACGATCCTTGGAACGTAAAGCCGCTTTCTAACTCGGAGTGTTCTAC
TTTAAAAGATTCCCTAATATCGTTTTTGATCTCTTCTGGAAAATTTAAGAAAGTAGGAGAGTATTTGTTTCCTTTGTAA

Upstream 100 bases:

>100_bases
TTTTTTAATTTATTTTTATTTTTCGGAAAATGGAATCGGAATTTTTATCGTTTCTTTCGCTTGTTTAACCGTATTCTTAT
TTAGGAATATCAAAGTTTCA

Downstream 100 bases:

>100_bases
GATTCTCTTTTCTTTATAGATTGGGTTTATAGTATTTTTGAAACATTTAACGACTCTCGAATTTGTAGCCAAAGCAATCA
ATTGATGCTTGAAGGATAGG

Product: arylsulfatase

Products: A Phenol; Sulfate. [C]

Alternate protein names: Phosphonate Monoester Hydrolase; Arylsulfatase; AryLSUlfatase A Family Protein

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MLIGSISFLFAVVSLLNARSITKTEISPVFLNLPNILILSADSLRYDKMGYAEGKEGMTPNIDLLSKDSIIFEDHHTTIP
RTFPAWADLLTGQPSFIHGIQDMFPDKKDREGLTFKTLPKLLSQLGYKTNVVSSFAGDIFPRADWGFRSVQAPIFHAGTL
TSQRILETQIFLLPIVTGSVPGAGEYFPAIRGLPSLGDDSKILPDLWNSFEKNEEPFFTVFFSSVTHFPFSPPYPHYKNF
TNSEYYGKFKYFKFVDPGDSSEPSLEDKEQIRGLFQASIYSFDQTVGKVVERLKKKGIYDSTLIVLTSDHGESLFEADHN
HGHGEHLRGEGVTHIPLLIKLPKNLGAGIRFSGISSSLDLFPTLLTFVSKEIQDPSIRNQFLKELSSRSGRDLSFALNST
TWKDSRNVYGETGIWFSDLGDHFFQKERIFYPSILHLHSIESGELPFISIGDSYAKESIIVSKHRMFQNSNRKLIYIPSE
DGVIWRCYDRINDPWNVKPLSNSECSTLKDSLISFLISSGKFKKVGEYLFPL

Sequences:

>Translated_532_residues
MLIGSISFLFAVVSLLNARSITKTEISPVFLNLPNILILSADSLRYDKMGYAEGKEGMTPNIDLLSKDSIIFEDHHTTIP
RTFPAWADLLTGQPSFIHGIQDMFPDKKDREGLTFKTLPKLLSQLGYKTNVVSSFAGDIFPRADWGFRSVQAPIFHAGTL
TSQRILETQIFLLPIVTGSVPGAGEYFPAIRGLPSLGDDSKILPDLWNSFEKNEEPFFTVFFSSVTHFPFSPPYPHYKNF
TNSEYYGKFKYFKFVDPGDSSEPSLEDKEQIRGLFQASIYSFDQTVGKVVERLKKKGIYDSTLIVLTSDHGESLFEADHN
HGHGEHLRGEGVTHIPLLIKLPKNLGAGIRFSGISSSLDLFPTLLTFVSKEIQDPSIRNQFLKELSSRSGRDLSFALNST
TWKDSRNVYGETGIWFSDLGDHFFQKERIFYPSILHLHSIESGELPFISIGDSYAKESIIVSKHRMFQNSNRKLIYIPSE
DGVIWRCYDRINDPWNVKPLSNSECSTLKDSLISFLISSGKFKKVGEYLFPL
>Mature_532_residues
MLIGSISFLFAVVSLLNARSITKTEISPVFLNLPNILILSADSLRYDKMGYAEGKEGMTPNIDLLSKDSIIFEDHHTTIP
RTFPAWADLLTGQPSFIHGIQDMFPDKKDREGLTFKTLPKLLSQLGYKTNVVSSFAGDIFPRADWGFRSVQAPIFHAGTL
TSQRILETQIFLLPIVTGSVPGAGEYFPAIRGLPSLGDDSKILPDLWNSFEKNEEPFFTVFFSSVTHFPFSPPYPHYKNF
TNSEYYGKFKYFKFVDPGDSSEPSLEDKEQIRGLFQASIYSFDQTVGKVVERLKKKGIYDSTLIVLTSDHGESLFEADHN
HGHGEHLRGEGVTHIPLLIKLPKNLGAGIRFSGISSSLDLFPTLLTFVSKEIQDPSIRNQFLKELSSRSGRDLSFALNST
TWKDSRNVYGETGIWFSDLGDHFFQKERIFYPSILHLHSIESGELPFISIGDSYAKESIIVSKHRMFQNSNRKLIYIPSE
DGVIWRCYDRINDPWNVKPLSNSECSTLKDSLISFLISSGKFKKVGEYLFPL

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.6.1 [C]

Molecular weight: Translated: 60055; Mature: 60055

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGSISFLFAVVSLLNARSITKTEISPVFLNLPNILILSADSLRYDKMGYAEGKEGMTP
CEECHHHHHHHHHHHHHCCCCCHHCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCC
NIDLLSKDSIIFEDHHTTIPRTFPAWADLLTGQPSFIHGIQDMFPDKKDREGLTFKTLPK
CCEEECCCCEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
LLSQLGYKTNVVSSFAGDIFPRADWGFRSVQAPIFHAGTLTSQRILETQIFLLPIVTGSV
HHHHCCCHHHHHHHHHHCCCCCCCCCCHHCCCCEEECCCCCHHHHHHHHEEEEEEEECCC
PGAGEYFPAIRGLPSLGDDSKILPDLWNSFEKNEEPFFTVFFSSVTHFPFSPPYPHYKNF
CCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCCCCCC
TNSEYYGKFKYFKFVDPGDSSEPSLEDKEQIRGLFQASIYSFDQTVGKVVERLKKKGIYD
CCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
STLIVLTSDHGESLFEADHNHGHGEHLRGEGVTHIPLLIKLPKNLGAGIRFSGISSSLDL
CEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEECCCCCHHHH
FPTLLTFVSKEIQDPSIRNQFLKELSSRSGRDLSFALNSTTWKDSRNVYGETGIWFSDLG
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
DHFFQKERIFYPSILHLHSIESGELPFISIGDSYAKESIIVSKHRMFQNSNRKLIYIPSE
HHHHHHCCCCCCHHHEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
DGVIWRCYDRINDPWNVKPLSNSECSTLKDSLISFLISSGKFKKVGEYLFPL
CCEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLIGSISFLFAVVSLLNARSITKTEISPVFLNLPNILILSADSLRYDKMGYAEGKEGMTP
CEECHHHHHHHHHHHHHCCCCCHHCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCC
NIDLLSKDSIIFEDHHTTIPRTFPAWADLLTGQPSFIHGIQDMFPDKKDREGLTFKTLPK
CCEEECCCCEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
LLSQLGYKTNVVSSFAGDIFPRADWGFRSVQAPIFHAGTLTSQRILETQIFLLPIVTGSV
HHHHCCCHHHHHHHHHHCCCCCCCCCCHHCCCCEEECCCCCHHHHHHHHEEEEEEEECCC
PGAGEYFPAIRGLPSLGDDSKILPDLWNSFEKNEEPFFTVFFSSVTHFPFSPPYPHYKNF
CCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCCCCCC
TNSEYYGKFKYFKFVDPGDSSEPSLEDKEQIRGLFQASIYSFDQTVGKVVERLKKKGIYD
CCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
STLIVLTSDHGESLFEADHNHGHGEHLRGEGVTHIPLLIKLPKNLGAGIRFSGISSSLDL
CEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEECCCCCHHHH
FPTLLTFVSKEIQDPSIRNQFLKELSSRSGRDLSFALNSTTWKDSRNVYGETGIWFSDLG
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
DHFFQKERIFYPSILHLHSIESGELPFISIGDSYAKESIIVSKHRMFQNSNRKLIYIPSE
HHHHHHCCCCCCHHHEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
DGVIWRCYDRINDPWNVKPLSNSECSTLKDSLISFLISSGKFKKVGEYLFPL
CCEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Phenol Sulfate; H2O [C]

Specific reaction: A Phenol Sulfate + H2O = A Phenol + Sulfate. [C]

General reaction: Sulfuric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA