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The map label for this gene is ruvC

Identifier: 45658715

GI number: 45658715

Start: 3487108

End: 3487680

Strand: Reverse

Name: ruvC

Synonym: LIC12885

Alternate gene names: 45658715

Gene position: 3487680-3487108 (Counterclockwise)

Preceding gene: 45658716

Following gene: 45658714

Centisome position: 81.54

GC content: 37.17

Gene sequence:

>573_bases
TTGTTACGCACTTTCGGATCTTTACAAAAATGGTCGTTGATTTTGGATACTATTTTCATGCGTTCGAGTAGTAGTTCTTT
GAGAATTATAGGAATCGACCCTGGTTCACATAGAGCTGGTTATGCGGTTTTAGAAAAAAACGCTTCTAAAATCAAAATTT
TAAATTATGGAACCGTAGAAGTTCCTTCTGGAACTCCTAGCCCTGATAATCTTTTGATGCTGCGAAAGGGACTTAGGGAA
ATTCTAGAAGAATTTAATCCCTCCATTGCTTCCGTGGAAGAAATGTTTTTTGCCAAAAATAAAAAAACGGCTTCTCGTGT
GTTTGAATCTAGAGGTGTTCTTTTAGTTACTTTAGCAGAACTGAATATTCGAATTTTAGAACCTACTGTTTCTCAGATCA
AAAAAGGAACCACTGGAAGCGGAACTGCGGATAAAAAACAAATTCGTCATGCTTTAAAACTTCTTTTAAACGTAGAATTG
TTAAAAGGACACGACGATTCTTGGGACGCAATTGCTGCGGCTTACGTTGGGCTTTCAATGAGTTCTAGCCCTTTGTTATC
TAAACTTCGATAG

Upstream 100 bases:

>100_bases
AATTATTCAGGTATATAAAATAATACTATGACGAGCTTTTTTCAAAATTTAGAATGTGATACATCTTTCAAAAAAGAAAA
TCATTCCGTGTTAGACGCAA

Downstream 100 bases:

>100_bases
AGCTTAATTTCAAACTCTTTTATTCAACTTTGTCAATAGTTTGACTTTTGATTTTACTCAAAGACATAATAAAATACCCA
GTTCAAATAGTTTATACTTC

Product: putative holliday junction endodeoxyribonuclease protein

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MLRTFGSLQKWSLILDTIFMRSSSSSLRIIGIDPGSHRAGYAVLEKNASKIKILNYGTVEVPSGTPSPDNLLMLRKGLRE
ILEEFNPSIASVEEMFFAKNKKTASRVFESRGVLLVTLAELNIRILEPTVSQIKKGTTGSGTADKKQIRHALKLLLNVEL
LKGHDDSWDAIAAAYVGLSMSSSPLLSKLR

Sequences:

>Translated_190_residues
MLRTFGSLQKWSLILDTIFMRSSSSSLRIIGIDPGSHRAGYAVLEKNASKIKILNYGTVEVPSGTPSPDNLLMLRKGLRE
ILEEFNPSIASVEEMFFAKNKKTASRVFESRGVLLVTLAELNIRILEPTVSQIKKGTTGSGTADKKQIRHALKLLLNVEL
LKGHDDSWDAIAAAYVGLSMSSSPLLSKLR
>Mature_190_residues
MLRTFGSLQKWSLILDTIFMRSSSSSLRIIGIDPGSHRAGYAVLEKNASKIKILNYGTVEVPSGTPSPDNLLMLRKGLRE
ILEEFNPSIASVEEMFFAKNKKTASRVFESRGVLLVTLAELNIRILEPTVSQIKKGTTGSGTADKKQIRHALKLLLNVEL
LKGHDDSWDAIAAAYVGLSMSSSPLLSKLR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=128, Percent_Identity=31.25, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 20871; Mature: 20871

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTFGSLQKWSLILDTIFMRSSSSSLRIIGIDPGSHRAGYAVLEKNASKIKILNYGTVE
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHEEECCCCEEEEEECCEEE
VPSGTPSPDNLLMLRKGLREILEEFNPSIASVEEMFFAKNKKTASRVFESRGVLLVTLAE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEC
LNIRILEPTVSQIKKGTTGSGTADKKQIRHALKLLLNVELLKGHDDSWDAIAAAYVGLSM
CCEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
SSSPLLSKLR
CCCHHHHHCC
>Mature Secondary Structure
MLRTFGSLQKWSLILDTIFMRSSSSSLRIIGIDPGSHRAGYAVLEKNASKIKILNYGTVE
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHEEECCCCEEEEEECCEEE
VPSGTPSPDNLLMLRKGLREILEEFNPSIASVEEMFFAKNKKTASRVFESRGVLLVTLAE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEC
LNIRILEPTVSQIKKGTTGSGTADKKQIRHALKLLLNVELLKGHDDSWDAIAAAYVGLSM
CCEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
SSSPLLSKLR
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA