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The map label for this gene is nuoJ

Identifier: 45658582

GI number: 45658582

Start: 3344107

End: 3344808

Strand: Direct

Name: nuoJ

Synonym: LIC12748

Alternate gene names: 45658582

Gene position: 3344107-3344808 (Clockwise)

Preceding gene: 45658581

Following gene: 45658583

Centisome position: 78.18

GC content: 42.31

Gene sequence:

>702_bases
ATGTCATTTACAGATCAACCTCAACTGCTTTTGTTTTTTCTATTCGCTTCGGTGATGATACTCAGTTCGTTGGGAGTGAT
TTTTCATCCGAACCCAATCACTGCCGCGGTGCTTTTAGTGCTCAGTTTTTTTTCACTAGCGGCGATCTACGCGGTGATGA
ACGCGATCTTTATCGCCACGATGCAGCTACTGGTTTACGCCGGGGCGATTATGGTTTTGGTAGTATTTGTGTTGATGTTA
CTGTCGCTTCGGGACGATGCACCTCGGTTTTTTATCTTCGAAAAACCAATTAAAAAACTCTTATATTTGGGATTGGTAAT
GTTTTTAGGTGTACTTTTAATCACCGCGGTTCAAGATGGAATTCCATCCGAAACCACGGTTCCGATCGGGTATGCTCAAA
ATAAAGACGGAAAATTTGTAGGTTATTCGTTTCAGATTTCTAAAAACATAAAACAAACGAACACAAAATCAACTTTGGAA
ACTCCGAAGACTACTTCCGAAAATCAGAACCATGTACACGAGAAAGATACGGACCAAATCATTCTCACTTCCGGAAATAC
CGCAGCCGTAGGAAGCGCGATGTTTTTACGTTATCTACTTCCTTTTGAGCTCATCTCCGTATTGCTACTTGCGGCGGTGC
TTGGCGCGGTAGTACTCGGAAAAAAGAATTTAGGAAGGAACACGGAAGGAGAAACCTTATGA

Upstream 100 bases:

>100_bases
GATCAACTGATGTCTTTGGGATGGAAAAAACTCATTCCTTGGGCGATTTTGAACATACTAATCGCGAGTATCTATATACA
ATTTTAAGAATATAAGAAAT

Downstream 100 bases:

>100_bases
ACCACTTTATATCCGGAATTCCGATCCACTACTACCTCATACTTGCGATGATCATTTTCACAATCGGAGTCGCGGGAGTG
ATGGTAAGAAGAAGCGCGGT

Product: NADH dehydrogenase I subunit J

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I, chain 6; NDH-1, chain 6 [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSFTDQPQLLLFFLFASVMILSSLGVIFHPNPITAAVLLVLSFFSLAAIYAVMNAIFIATMQLLVYAGAIMVLVVFVLML
LSLRDDAPRFFIFEKPIKKLLYLGLVMFLGVLLITAVQDGIPSETTVPIGYAQNKDGKFVGYSFQISKNIKQTNTKSTLE
TPKTTSENQNHVHEKDTDQIILTSGNTAAVGSAMFLRYLLPFELISVLLLAAVLGAVVLGKKNLGRNTEGETL

Sequences:

>Translated_233_residues
MSFTDQPQLLLFFLFASVMILSSLGVIFHPNPITAAVLLVLSFFSLAAIYAVMNAIFIATMQLLVYAGAIMVLVVFVLML
LSLRDDAPRFFIFEKPIKKLLYLGLVMFLGVLLITAVQDGIPSETTVPIGYAQNKDGKFVGYSFQISKNIKQTNTKSTLE
TPKTTSENQNHVHEKDTDQIILTSGNTAAVGSAMFLRYLLPFELISVLLLAAVLGAVVLGKKNLGRNTEGETL
>Mature_232_residues
SFTDQPQLLLFFLFASVMILSSLGVIFHPNPITAAVLLVLSFFSLAAIYAVMNAIFIATMQLLVYAGAIMVLVVFVLMLL
SLRDDAPRFFIFEKPIKKLLYLGLVMFLGVLLITAVQDGIPSETTVPIGYAQNKDGKFVGYSFQISKNIKQTNTKSTLET
PKTTSENQNHVHEKDTDQIILTSGNTAAVGSAMFLRYLLPFELISVLLLAAVLGAVVLGKKNLGRNTEGETL

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG0839

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 6 (chain J)

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001457 [H]

Pfam domain/function: PF00499 Oxidored_q3 [H]

EC number: 1.6.5.3

Molecular weight: Translated: 25497; Mature: 25365

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTDQPQLLLFFLFASVMILSSLGVIFHPNPITAAVLLVLSFFSLAAIYAVMNAIFIAT
CCCCCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQLLVYAGAIMVLVVFVLMLLSLRDDAPRFFIFEKPIKKLLYLGLVMFLGVLLITAVQDG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPSETTVPIGYAQNKDGKFVGYSFQISKNIKQTNTKSTLETPKTTSENQNHVHEKDTDQI
CCCCCEECCCCCCCCCCCEEEEEEEECCCHHHCCCCHHCCCCCCCCCCCCCCCCCCCCEE
ILTSGNTAAVGSAMFLRYLLPFELISVLLLAAVLGAVVLGKKNLGRNTEGETL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCC
>Mature Secondary Structure 
SFTDQPQLLLFFLFASVMILSSLGVIFHPNPITAAVLLVLSFFSLAAIYAVMNAIFIAT
CCCCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQLLVYAGAIMVLVVFVLMLLSLRDDAPRFFIFEKPIKKLLYLGLVMFLGVLLITAVQDG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPSETTVPIGYAQNKDGKFVGYSFQISKNIKQTNTKSTLETPKTTSENQNHVHEKDTDQI
CCCCCEECCCCCCCCCCCEEEEEEEECCCHHHCCCCHHCCCCCCCCCCCCCCCCCCCCEE
ILTSGNTAAVGSAMFLRYLLPFELISVLLLAAVLGAVVLGKKNLGRNTEGETL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1463844; 8590279; 8905231 [H]