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The map label for this gene is lnt

Identifier: 45658397

GI number: 45658397

Start: 3096271

End: 3098001

Strand: Direct

Name: lnt

Synonym: LIC12556

Alternate gene names: 45658397

Gene position: 3096271-3098001 (Clockwise)

Preceding gene: 45658396

Following gene: 45658398

Centisome position: 72.39

GC content: 34.49

Gene sequence:

>1731_bases
ATGTTTTACAATTTTATTTCCAAAGATTCGATTTTGTACCGACTTATACTGTGTTTTGGAATTGGAATCGGAACCGTGTT
CGGACTTTCTCCGTTTTCGTTTTTTTCGGCGGGTGTATTTGCGTCTATCTCTTGTATTTTTTTGTTTTTTTCCCTCAATA
GAACTTCTATTTGGAAAGCTTTCTTGTGGCTTTTGATACTTTCTCAAATTTTAAACTTCACTGCTTTTTATTGGATTCCA
GGAGCAATTTCTAGAATTTCTGGTGCAAACACTTTTGTTTCCATACTTTTCTTTTTTTTATACGGACTAATCTCTCATTT
AAAGTTTTTTTTGTTTTATACTCTATTCCGCTTTTCTAAAATAGATTCTGCTTCAAAAACTTATATATTACTTATATTTC
CCGCCGCTGGAACACTCTCCGATATGATAACGTTTCAAATTTTCCCCTGGTATTGGGGAAACTTAATCTCAGGTTCCATC
GTATTTGAACAATTCGCTTCCATTTGCGGAGTATACGGATTGAGTTTTCTTTTACTATTCATATCATCCACTTTTTTAAT
ATTAGTAAATTATTATAAATATAAAAATTCAAAAGAATTCAAAACTTCGATCGCAAGTTTGATCTGTATCGCGTTTATAT
ATAGATTCGGTCTTTATCGGATTGGATATATAAACCAATCACAAAATGAATTAAAACCTAAAAATCTCTCCGTGCTTATG
ATTCAACCGGACACCTCTCCAGGCACAAAGGACTTAAAAGCAGACGCCTCTTATTTAAGCGCTACAATGAGTAAGGTATT
TTCCTTAGCCATACCTACTTTCGAAAATTCACCTTCTTTGATCGTAATTCCGGAATCCGCGATTCCGTTTCACGGTACAA
TCGATTCCGAAGAAAATCGGAAAGAAAAAATATATTCTTCTACAATGGAAGGTATCATTTTATATCTTTCAAAACATACA
GGAGCCGACGTTCTATTTAACGAATTAAATCTGGATGAAAACAAACTCAGAAATCAGGTTAGTCTTTTTAAAAACTTAGA
CGGCAAAACCGAGAGATACAATAAAAGAAGGTTACTTCCTTTTGGAGAATATCTACCGATGGAAAAAAATTTTCCTTTTT
TACGTTCTATCTTTCAAGAAACTTCCAGATATGTGCCGGGAGAATTTCCAAAACTTTTAATCGGAAATAAGATCCAAAAT
CAAAGATCGTTCTTACCTCCCGAAATTTCTAAATTGAACGAACCAAAAACGTATAGATACGAATTTTCATCCATTGTAGA
ACATACAAATAAAATTAGAAATTTAGAATATTCTTATTCGATCCTTCCTTTACTTTGTTACGAAGCTATGTTTACAGAAC
TTGTTTTGGATTATTTTCAAAACGAACAAAAACCGGAAGTTCTAATCAACATCACTAATGATTCTTGGTTCGATTCTGAA
TTAGAAGCCTATCAACATTCCGGGGCCGTTAGACTCAGGGCGATCGAAACCGGCTTACCTCTGATTCGCTCCGCAGTCTC
TGGAATTTCGGAAGTTTGGGACGCACGCGGAATTCCAATGATCGTTCCAATCGGTTTTCACGAAACCGGAACCAGGGCGT
TTTCTATCCGATTAGATGCTATCGAATCTACGATTTATACCAGATTTGGAAATTCTTTTCTATGGATCTTCTGTATTTTA
ATTCTGATTTCTCGTCTTATTTTCGTGTCACGAATAGAAAGGAAAAGTTAA

Upstream 100 bases:

>100_bases
AGCTCTAATGGAAATTCGGATCAAAAATCTAGGAAAGGAAGAAGCAGAAGAATATTCAAGAAGGCTTAAATATGAAGAGG
AAATAAAAAAATAAAAACAG

Downstream 100 bases:

>100_bases
TGTTGAGACATACCTTCTGTCATCTTCCCGGAATCGATTCCAAGGAAGAAAAAAATCTTTGGGAAAAAGGGATCTACGAC
TGGAAGGATCTGGAAATATA

Product: apolipoprotein n-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase 1

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MFYNFISKDSILYRLILCFGIGIGTVFGLSPFSFFSAGVFASISCIFLFFSLNRTSIWKAFLWLLILSQILNFTAFYWIP
GAISRISGANTFVSILFFFLYGLISHLKFFLFYTLFRFSKIDSASKTYILLIFPAAGTLSDMITFQIFPWYWGNLISGSI
VFEQFASICGVYGLSFLLLFISSTFLILVNYYKYKNSKEFKTSIASLICIAFIYRFGLYRIGYINQSQNELKPKNLSVLM
IQPDTSPGTKDLKADASYLSATMSKVFSLAIPTFENSPSLIVIPESAIPFHGTIDSEENRKEKIYSSTMEGIILYLSKHT
GADVLFNELNLDENKLRNQVSLFKNLDGKTERYNKRRLLPFGEYLPMEKNFPFLRSIFQETSRYVPGEFPKLLIGNKIQN
QRSFLPPEISKLNEPKTYRYEFSSIVEHTNKIRNLEYSYSILPLLCYEAMFTELVLDYFQNEQKPEVLINITNDSWFDSE
LEAYQHSGAVRLRAIETGLPLIRSAVSGISEVWDARGIPMIVPIGFHETGTRAFSIRLDAIESTIYTRFGNSFLWIFCIL
ILISRLIFVSRIERKS

Sequences:

>Translated_576_residues
MFYNFISKDSILYRLILCFGIGIGTVFGLSPFSFFSAGVFASISCIFLFFSLNRTSIWKAFLWLLILSQILNFTAFYWIP
GAISRISGANTFVSILFFFLYGLISHLKFFLFYTLFRFSKIDSASKTYILLIFPAAGTLSDMITFQIFPWYWGNLISGSI
VFEQFASICGVYGLSFLLLFISSTFLILVNYYKYKNSKEFKTSIASLICIAFIYRFGLYRIGYINQSQNELKPKNLSVLM
IQPDTSPGTKDLKADASYLSATMSKVFSLAIPTFENSPSLIVIPESAIPFHGTIDSEENRKEKIYSSTMEGIILYLSKHT
GADVLFNELNLDENKLRNQVSLFKNLDGKTERYNKRRLLPFGEYLPMEKNFPFLRSIFQETSRYVPGEFPKLLIGNKIQN
QRSFLPPEISKLNEPKTYRYEFSSIVEHTNKIRNLEYSYSILPLLCYEAMFTELVLDYFQNEQKPEVLINITNDSWFDSE
LEAYQHSGAVRLRAIETGLPLIRSAVSGISEVWDARGIPMIVPIGFHETGTRAFSIRLDAIESTIYTRFGNSFLWIFCIL
ILISRLIFVSRIERKS
>Mature_576_residues
MFYNFISKDSILYRLILCFGIGIGTVFGLSPFSFFSAGVFASISCIFLFFSLNRTSIWKAFLWLLILSQILNFTAFYWIP
GAISRISGANTFVSILFFFLYGLISHLKFFLFYTLFRFSKIDSASKTYILLIFPAAGTLSDMITFQIFPWYWGNLISGSI
VFEQFASICGVYGLSFLLLFISSTFLILVNYYKYKNSKEFKTSIASLICIAFIYRFGLYRIGYINQSQNELKPKNLSVLM
IQPDTSPGTKDLKADASYLSATMSKVFSLAIPTFENSPSLIVIPESAIPFHGTIDSEENRKEKIYSSTMEGIILYLSKHT
GADVLFNELNLDENKLRNQVSLFKNLDGKTERYNKRRLLPFGEYLPMEKNFPFLRSIFQETSRYVPGEFPKLLIGNKIQN
QRSFLPPEISKLNEPKTYRYEFSSIVEHTNKIRNLEYSYSILPLLCYEAMFTELVLDYFQNEQKPEVLINITNDSWFDSE
LEAYQHSGAVRLRAIETGLPLIRSAVSGISEVWDARGIPMIVPIGFHETGTRAFSIRLDAIESTIYTRFGNSFLWIFCIL
ILISRLIFVSRIERKS

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=596, Percent_Identity=26.1744966442953, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT1_LEPIC (Q72PB6)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_002483.1
- ProteinModelPortal:   Q72PB6
- GeneID:   2770009
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC12556
- NMPDR:   fig|267671.1.peg.2483
- HOGENOM:   HBG110159
- OMA:   MMAFIRR
- ProtClustDB:   CLSK2304428
- BioCyc:   LINT267671:LIC_12556-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 66200; Mature: 66200

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11fdd40c)-; HASH(0x118b3628)-; HASH(0xd8885f4)-; HASH(0x1246a254)-; HASH(0x12458738)-; HASH(0x1247ed50)-; HASH(0x12488e40)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYNFISKDSILYRLILCFGIGIGTVFGLSPFSFFSAGVFASISCIFLFFSLNRTSIWKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FLWLLILSQILNFTAFYWIPGAISRISGANTFVSILFFFLYGLISHLKFFLFYTLFRFSK
HHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSASKTYILLIFPAAGTLSDMITFQIFPWYWGNLISGSIVFEQFASICGVYGLSFLLLF
CCCCCCEEEEEEECCCCCHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSTFLILVNYYKYKNSKEFKTSIASLICIAFIYRFGLYRIGYINQSQNELKPKNLSVLM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEE
IQPDTSPGTKDLKADASYLSATMSKVFSLAIPTFENSPSLIVIPESAIPFHGTIDSEENR
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHH
KEKIYSSTMEGIILYLSKHTGADVLFNELNLDENKLRNQVSLFKNLDGKTERYNKRRLLP
HHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCC
FGEYLPMEKNFPFLRSIFQETSRYVPGEFPKLLIGNKIQNQRSFLPPEISKLNEPKTYRY
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCCCHHHH
EFSSIVEHTNKIRNLEYSYSILPLLCYEAMFTELVLDYFQNEQKPEVLINITNDSWFDSE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LEAYQHSGAVRLRAIETGLPLIRSAVSGISEVWDARGIPMIVPIGFHETGTRAFSIRLDA
HHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEHHH
IESTIYTRFGNSFLWIFCILILISRLIFVSRIERKS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MFYNFISKDSILYRLILCFGIGIGTVFGLSPFSFFSAGVFASISCIFLFFSLNRTSIWKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FLWLLILSQILNFTAFYWIPGAISRISGANTFVSILFFFLYGLISHLKFFLFYTLFRFSK
HHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSASKTYILLIFPAAGTLSDMITFQIFPWYWGNLISGSIVFEQFASICGVYGLSFLLLF
CCCCCCEEEEEEECCCCCHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSTFLILVNYYKYKNSKEFKTSIASLICIAFIYRFGLYRIGYINQSQNELKPKNLSVLM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEE
IQPDTSPGTKDLKADASYLSATMSKVFSLAIPTFENSPSLIVIPESAIPFHGTIDSEENR
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHH
KEKIYSSTMEGIILYLSKHTGADVLFNELNLDENKLRNQVSLFKNLDGKTERYNKRRLLP
HHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCC
FGEYLPMEKNFPFLRSIFQETSRYVPGEFPKLLIGNKIQNQRSFLPPEISKLNEPKTYRY
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCCCHHHH
EFSSIVEHTNKIRNLEYSYSILPLLCYEAMFTELVLDYFQNEQKPEVLINITNDSWFDSE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LEAYQHSGAVRLRAIETGLPLIRSAVSGISEVWDARGIPMIVPIGFHETGTRAFSIRLDA
HHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEHHH
IESTIYTRFGNSFLWIFCILILISRLIFVSRIERKS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA