| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is cyaA [H]
Identifier: 45658348
GI number: 45658348
Start: 3034883
End: 3036475
Strand: Direct
Name: cyaA [H]
Synonym: LIC12506
Alternate gene names: 45658348
Gene position: 3034883-3036475 (Clockwise)
Preceding gene: 45658342
Following gene: 45658350
Centisome position: 70.96
GC content: 38.48
Gene sequence:
>1593_bases ATGATTCTTGTAAATTTTGAAAACGAAAAAGAAATTAGTTTATCCAAGCCCCAGAACCTGTTAGAAATTAGTCTAAACAA CGGTATTCCACATACACACGCCTGCGGCGGAAATGCTCGATGCTCTACTTGTCGCGTTTTGGTTTTAGAAAACCCTTCTC ATCTATCTCCTCCAGAACAAAAAGAAAAAGAACTCTCTCAAAAAAAAGGTTTTCCTAAATCCGTTCGACTTGCGTGCCAG ACAACAGTTTTAGGCGACGTTCGGGTTCGAAGAATCGTTTTAGACGAAGAAGATTATAATCTTACAATTCCAGGATCAGC CACAATTTCAGGAGAAGAAAAAGAAATCGCGATCCTTTTCAGCGATATTCGAGATTTTACTCTATTTTCCGAATCACATC TTCCTTACGATGTAATTCATATACTCAACCGATATTTTTATAAAATGGGGGACGTGATTTTAAAACACGGAGGTAAAATA GATAAATATATCGGAGACGGACTCATGGCTCTCTTCGGAGTTAACGGTGGTTCTCCTCAAGAAATTTGTATCTCCGCTCT GCGTGCCGCCAAGGAGATGGAGTTAGAACTCTACTCCCTTAACGAATATCTAAAGTCTCATCTTCATACTTCGTTCCGTA TCGGCGTAGGAGTACATTACGGAAATTGTATATTAGGACAATTGGGTCATCCTGCAAATATGTCTTACACGGCTATCGGT GATTCCGTAAACATAGCGAGCAGAATCGAATCTAAAACCAAAAAATCGGGCGCTTCCGTTTTGATTTCCGAATCTCTCTA CAAACAAGTAAAAGAAAAAGTTGTCAAAGGCAGAGTTTTTTCCGCACAACTCAAAGGAAAAACCGGAAATTATAAACTCT ATGAGATTCAGGAAATTTTGGAAAAAGTAGATGCGAATCTCTGGGAAGAAGCTAAAAATTCTCTCCGAAGAATCATACTT GTTCGAGAAGTAGGAAGTTGGTTAAAACTAGTTTACCATCTCTCTTGTCTTTTTGACGAAAATCAAAACTGGATCGGACT TTCTGCTGCAAACTCTTTTCAAAAGTTTTCCAAACTTCCGGAAAACGGAGATTTGGTTCAAAATTTTTATCAAATCAAAG ATACGTTTAACGAACAATTTCAAAACTCTTTTTCCTTTGCAGACCTTTTAGCTCTCGCCGGTGCAGTCGCTATCGAAAAA TCAGGTGGCCCAAAAATCCCGATTCAACCTGGAAGAAAAGATCGATTGTTAAGCGAAGTATTTCAAATTCTTCCACTGAG TATGCAGACTCAAAAAGACCAACTCCCATATCTTCAAAAAATGAAACTGGGAATTAGAGATATAGTCCTGATTTCAGGAG CGCGTACAATCGGATGGTTAGGCGGGGAATCGTTTACTTCGAACCCTTATAACTTTGATAATAGTTATTTCCATGTTCTT CTCAAAGCGGGATTAGAAGGTCCATTATTGATTCCGAACGATAGAGAACTTTTGAAAAACGATGAATCCAGAGCCTTTGT GTTGGATTACGCCCTGGATCCTTCTAAGTTTTTCGAAGACTTTACTTCTACATACTTAAAACTTACAAGTTAA
Upstream 100 bases:
>100_bases TGCCGAGTTCTTCTATTGACAACCAGGTCTGTAATTCTCTACCCTTCCATATAGGACGCCAATTATTTTTTTATATCTCC GTGAAATCCGGTAGGTTTTA
Downstream 100 bases:
>100_bases TCTACAAATCGTCTTCTAACGGGAAAAGTTCTTGAATTTCATTTCCCACGAGGCGATCAAAATTTTCGAACGACTCTAGT ATTTCTTGCATTAAACTATC
Product: adenylate/guanylate cyclase
Products: NA
Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]
Number of amino acids: Translated: 530; Mature: 530
Protein sequence:
>530_residues MILVNFENEKEISLSKPQNLLEISLNNGIPHTHACGGNARCSTCRVLVLENPSHLSPPEQKEKELSQKKGFPKSVRLACQ TTVLGDVRVRRIVLDEEDYNLTIPGSATISGEEKEIAILFSDIRDFTLFSESHLPYDVIHILNRYFYKMGDVILKHGGKI DKYIGDGLMALFGVNGGSPQEICISALRAAKEMELELYSLNEYLKSHLHTSFRIGVGVHYGNCILGQLGHPANMSYTAIG DSVNIASRIESKTKKSGASVLISESLYKQVKEKVVKGRVFSAQLKGKTGNYKLYEIQEILEKVDANLWEEAKNSLRRIIL VREVGSWLKLVYHLSCLFDENQNWIGLSAANSFQKFSKLPENGDLVQNFYQIKDTFNEQFQNSFSFADLLALAGAVAIEK SGGPKIPIQPGRKDRLLSEVFQILPLSMQTQKDQLPYLQKMKLGIRDIVLISGARTIGWLGGESFTSNPYNFDNSYFHVL LKAGLEGPLLIPNDRELLKNDESRAFVLDYALDPSKFFEDFTSTYLKLTS
Sequences:
>Translated_530_residues MILVNFENEKEISLSKPQNLLEISLNNGIPHTHACGGNARCSTCRVLVLENPSHLSPPEQKEKELSQKKGFPKSVRLACQ TTVLGDVRVRRIVLDEEDYNLTIPGSATISGEEKEIAILFSDIRDFTLFSESHLPYDVIHILNRYFYKMGDVILKHGGKI DKYIGDGLMALFGVNGGSPQEICISALRAAKEMELELYSLNEYLKSHLHTSFRIGVGVHYGNCILGQLGHPANMSYTAIG DSVNIASRIESKTKKSGASVLISESLYKQVKEKVVKGRVFSAQLKGKTGNYKLYEIQEILEKVDANLWEEAKNSLRRIIL VREVGSWLKLVYHLSCLFDENQNWIGLSAANSFQKFSKLPENGDLVQNFYQIKDTFNEQFQNSFSFADLLALAGAVAIEK SGGPKIPIQPGRKDRLLSEVFQILPLSMQTQKDQLPYLQKMKLGIRDIVLISGARTIGWLGGESFTSNPYNFDNSYFHVL LKAGLEGPLLIPNDRELLKNDESRAFVLDYALDPSKFFEDFTSTYLKLTS >Mature_530_residues MILVNFENEKEISLSKPQNLLEISLNNGIPHTHACGGNARCSTCRVLVLENPSHLSPPEQKEKELSQKKGFPKSVRLACQ TTVLGDVRVRRIVLDEEDYNLTIPGSATISGEEKEIAILFSDIRDFTLFSESHLPYDVIHILNRYFYKMGDVILKHGGKI DKYIGDGLMALFGVNGGSPQEICISALRAAKEMELELYSLNEYLKSHLHTSFRIGVGVHYGNCILGQLGHPANMSYTAIG DSVNIASRIESKTKKSGASVLISESLYKQVKEKVVKGRVFSAQLKGKTGNYKLYEIQEILEKVDANLWEEAKNSLRRIIL VREVGSWLKLVYHLSCLFDENQNWIGLSAANSFQKFSKLPENGDLVQNFYQIKDTFNEQFQNSFSFADLLALAGAVAIEK SGGPKIPIQPGRKDRLLSEVFQILPLSMQTQKDQLPYLQKMKLGIRDIVLISGARTIGWLGGESFTSNPYNFDNSYFHVL LKAGLEGPLLIPNDRELLKNDESRAFVLDYALDPSKFFEDFTSTYLKLTS
Specific function: Unknown
COG id: COG2114
COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 guanylate cyclase domain [H]
Homologues:
Organism=Caenorhabditis elegans, GI193206632, Length=142, Percent_Identity=34.5070422535211, Blast_Score=72, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001054 [H]
Pfam domain/function: PF00211 Guanylate_cyc [H]
EC number: =4.6.1.1 [H]
Molecular weight: Translated: 59460; Mature: 59460
Theoretical pI: Translated: 7.34; Mature: 7.34
Prosite motif: PS50873 PEROXIDASE_4 ; PS50125 GUANYLATE_CYCLASES_2 ; PS51085 2FE2S_FER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MILVNFENEKEISLSKPQNLLEISLNNGIPHTHACGGNARCSTCRVLVLENPSHLSPPEQ CEEEEECCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHH KEKELSQKKGFPKSVRLACQTTVLGDVRVRRIVLDEEDYNLTIPGSATISGEEKEIAILF HHHHHHHHCCCCHHHHHEEHHEEECCCEEEEEEECCCCCEEECCCCCEECCCCCEEEEEE SDIRDFTLFSESHLPYDVIHILNRYFYKMGDVILKHGGKIDKYIGDGLMALFGVNGGSPQ ECHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCCCHH EICISALRAAKEMELELYSLNEYLKSHLHTSFRIGVGVHYGNCILGQLGHPANMSYTAIG HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCCCCEEEEEC DSVNIASRIESKTKKSGASVLISESLYKQVKEKVVKGRVFSAQLKGKTGNYKLYEIQEIL CCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCEEHHHHHHHH EKVDANLWEEAKNSLRRIILVREVGSWLKLVYHLSCLFDENQNWIGLSAANSFQKFSKLP HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEHHHHHHHHHHCCC ENGDLVQNFYQIKDTFNEQFQNSFSFADLLALAGAVAIEKSGGPKIPIQPGRKDRLLSEV CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHH FQILPLSMQTQKDQLPYLQKMKLGIRDIVLISGARTIGWLGGESFTSNPYNFDNSYFHVL HHHCCCCCCCCCCCCCHHHHHHCCHHEEEEEECCCEEEECCCCCCCCCCCCCCCHHHHHH LKAGLEGPLLIPNDRELLKNDESRAFVLDYALDPSKFFEDFTSTYLKLTS HHCCCCCCEECCCCHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHEEECC >Mature Secondary Structure MILVNFENEKEISLSKPQNLLEISLNNGIPHTHACGGNARCSTCRVLVLENPSHLSPPEQ CEEEEECCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHH KEKELSQKKGFPKSVRLACQTTVLGDVRVRRIVLDEEDYNLTIPGSATISGEEKEIAILF HHHHHHHHCCCCHHHHHEEHHEEECCCEEEEEEECCCCCEEECCCCCEECCCCCEEEEEE SDIRDFTLFSESHLPYDVIHILNRYFYKMGDVILKHGGKIDKYIGDGLMALFGVNGGSPQ ECHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCCCHH EICISALRAAKEMELELYSLNEYLKSHLHTSFRIGVGVHYGNCILGQLGHPANMSYTAIG HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCCCCEEEEEC DSVNIASRIESKTKKSGASVLISESLYKQVKEKVVKGRVFSAQLKGKTGNYKLYEIQEIL CCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCEEHHHHHHHH EKVDANLWEEAKNSLRRIILVREVGSWLKLVYHLSCLFDENQNWIGLSAANSFQKFSKLP HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEHHHHHHHHHHCCC ENGDLVQNFYQIKDTFNEQFQNSFSFADLLALAGAVAIEKSGGPKIPIQPGRKDRLLSEV CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHH FQILPLSMQTQKDQLPYLQKMKLGIRDIVLISGARTIGWLGGESFTSNPYNFDNSYFHVL HHHCCCCCCCCCCCCCHHHHHHCCHHEEEEEECCCEEEECCCCCCCCCCCCCCCHHHHHH LKAGLEGPLLIPNDRELLKNDESRAFVLDYALDPSKFFEDFTSTYLKLTS HHCCCCCCEECCCCHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9523018; 8418825 [H]