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The map label for this gene is mcpB

Identifier: 45658342

GI number: 45658342

Start: 3027333

End: 3029408

Strand: Direct

Name: mcpB

Synonym: LIC12500

Alternate gene names: 45658342

Gene position: 3027333-3029408 (Clockwise)

Preceding gene: 45658341

Following gene: 45658348

Centisome position: 70.78

GC content: 38.49

Gene sequence:

>2076_bases
ATGAGTATCCGATTTAGAATATCCCTGTATCTTGCCCTTGTGCTTATGGCAGGAAGTATAGCAATCACAGCCATCAATGC
AGTTTCAACTTATTTCAAACTAACACAGGATATCAAAGATTCTTCCTCCTTGATAGCATCCAGATACGCTTTCGAAATCC
AAGACTTTTTTGACAAGGCATTGGGAGGGCTAAGAGGAATAGAATTCCAACTTTCTCATGCAAGACCTACAAGAGAAGAA
ACGATCGAATCGTTGAAAGACCTGGCCGATTCGGACCCAAACTACTTCGGAACCTGGTCGGTATTTGAACCCGGAAAGTT
CGACTCGAACGATTTACAATATGTAAATAAACAAGGTTATGACTCAACCGGAAGGTTTATTCCATATCTCAATAAGTCCG
CCGGTGTAGACAGACCGCTCGTATTGGAACAAGTAGTCTATTACGAAAATCAAGATATGAGTGGATACTTTTATAATATT
CCTAAAAAAACCGGAAAAGATTATATCGCAGATCCATTTGCCTATCCGGTATCCGGAAAAGACGTTTTGATGATCTCAGT
GGCTAAACCGTTACGCAGAAATGGGGAATTTGCCGGAGTAGTAGGCATGGACATAACCATGAAAAACATGCAGGAGATGA
TTGCTCCCATACGTCCTTACCAAGGAAAAGGTTATTTAAATTTAATTTCTCCCGGAGGTTTTTATGCAGCGAACGGATTA
CAACCCGAACTCGTAGGAAAACCAATCCCAGATCCAGAATGGAAAAAACTAATACTAGAAGGAAGTCAGAAACAAGAAAT
CCAAATCTATGAAAAAGACAATTCCACACATTTTTTCTATTCCTTTTATTTAGGCAATTATGATAAGAAATGGATTTTAG
AAGTAAGTGTACCTTACGATATTTTTTGGAAAAATTTATCCATGATCATTTTGGAAACAATTACCACCTCATTAATCACC
ATGGTCGCGATTCTACTTGTGTTAAATCTAATATTCCAAAAATTGATTACGAATGGAATCAATACAGCGATTTCTTTTTC
CGAAGAAATTTCTTCTGGAAACTTAATAGTAGTCAATCAATACGAGCGAAAGGACGAAATCGGAAAGCTTCTTCTTTCTC
TCAATCAGATGAAGAATAACATCAAAAAAATCATATTCGAAATCAAAGGTTCTTCCGAATCCCTCAACTCTACCTCCGAT
AAAATGGCGGAATCTTCTAAAAGTTTTTACGACGTAGCCCAGGAACAAGCATCTGCATCAGAAGAATCTTCAGCAGCAAT
CGAAGAATTAGCCTCTTCCGCTGAGAACGTAGGCAGGTCGATGGAAAAGGCGATTTCACATATGAAAGATATAGACGGAA
ACGTAATTCTTTTGAAAGAACAAATCGTAAAAATTAATGAAGAGATGAAATCACTTTCCTTTCTCGCAAACGAATCACAA
CAACAAGCCGTTACGGGCGAAGGCTCCATGAATCAATCCACAAAAGCGATGGACGAAATTGGAGACAGCGCCTCTAGAAT
CAACGAAATTCTATCGATCATCACTGATATATCCGAAAAGACAAACTTACTCGCGTTAAACGCCGCAATCGAAGCGGCAA
GAGCAGGAGAAGCCGGAAAAGGTTTTGCGGTAGTTGCGGAAGAAATTTCTAAACTCGCCTCTCAAACCTCCAATAGCGTT
CAAGAAATAGGACAACTTGTAGAATCTACAAATCGTGCCGTAATGAACGGAACTGGAAAAGTAAAGGAAGCTTCCGAAAT
TCTTGCAAAACTTAGAAGTTCTGTGGATATGTTCGGAGTTTCAGCAAAAACGGTTTTGGATTCAGTAAACGCTCAAGAAA
AGAATACTGAAAAAATTCATAGTAGCGCTAGTTCTCTTATGAATTTTAGTCTTCAAATCGAAGAAGCTGTACAAGAACAA
AGACGAGCTTCTGATGAAATTGCAAAAACAATCCTAAGTATTTCAGAAGGAACTCAAGAGATTGCAAGCGGTGCAGATGA
TTTGACCGGATTTTCTAAAAATATGCATACCCAATCAGAAGGATTATTGCGCCTTATCAATCAGTTTAAGATTTAA

Upstream 100 bases:

>100_bases
CGAGAATCGTATTTATTGCAGAAAATCCCGGCGCATTTATTTTGGTTTAGCATCGGATTTTCCCACAGTTTTTAAGATAC
ACAAAAAGAGGAGGAAATTC

Downstream 100 bases:

>100_bases
GAATATTTAAGAAACGACAAAACCCAGTTTAATCCTGGGTTCCGTTTTGCCTTCTTAGAAAAAAACCAGGATCTACGGAA
TCTAAAATTCTTTTGGATTC

Product: chemoreceptor (methyl-accepting chemotaxis) transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MSIRFRISLYLALVLMAGSIAITAINAVSTYFKLTQDIKDSSSLIASRYAFEIQDFFDKALGGLRGIEFQLSHARPTREE
TIESLKDLADSDPNYFGTWSVFEPGKFDSNDLQYVNKQGYDSTGRFIPYLNKSAGVDRPLVLEQVVYYENQDMSGYFYNI
PKKTGKDYIADPFAYPVSGKDVLMISVAKPLRRNGEFAGVVGMDITMKNMQEMIAPIRPYQGKGYLNLISPGGFYAANGL
QPELVGKPIPDPEWKKLILEGSQKQEIQIYEKDNSTHFFYSFYLGNYDKKWILEVSVPYDIFWKNLSMIILETITTSLIT
MVAILLVLNLIFQKLITNGINTAISFSEEISSGNLIVVNQYERKDEIGKLLLSLNQMKNNIKKIIFEIKGSSESLNSTSD
KMAESSKSFYDVAQEQASASEESSAAIEELASSAENVGRSMEKAISHMKDIDGNVILLKEQIVKINEEMKSLSFLANESQ
QQAVTGEGSMNQSTKAMDEIGDSASRINEILSIITDISEKTNLLALNAAIEAARAGEAGKGFAVVAEEISKLASQTSNSV
QEIGQLVESTNRAVMNGTGKVKEASEILAKLRSSVDMFGVSAKTVLDSVNAQEKNTEKIHSSASSLMNFSLQIEEAVQEQ
RRASDEIAKTILSISEGTQEIASGADDLTGFSKNMHTQSEGLLRLINQFKI

Sequences:

>Translated_691_residues
MSIRFRISLYLALVLMAGSIAITAINAVSTYFKLTQDIKDSSSLIASRYAFEIQDFFDKALGGLRGIEFQLSHARPTREE
TIESLKDLADSDPNYFGTWSVFEPGKFDSNDLQYVNKQGYDSTGRFIPYLNKSAGVDRPLVLEQVVYYENQDMSGYFYNI
PKKTGKDYIADPFAYPVSGKDVLMISVAKPLRRNGEFAGVVGMDITMKNMQEMIAPIRPYQGKGYLNLISPGGFYAANGL
QPELVGKPIPDPEWKKLILEGSQKQEIQIYEKDNSTHFFYSFYLGNYDKKWILEVSVPYDIFWKNLSMIILETITTSLIT
MVAILLVLNLIFQKLITNGINTAISFSEEISSGNLIVVNQYERKDEIGKLLLSLNQMKNNIKKIIFEIKGSSESLNSTSD
KMAESSKSFYDVAQEQASASEESSAAIEELASSAENVGRSMEKAISHMKDIDGNVILLKEQIVKINEEMKSLSFLANESQ
QQAVTGEGSMNQSTKAMDEIGDSASRINEILSIITDISEKTNLLALNAAIEAARAGEAGKGFAVVAEEISKLASQTSNSV
QEIGQLVESTNRAVMNGTGKVKEASEILAKLRSSVDMFGVSAKTVLDSVNAQEKNTEKIHSSASSLMNFSLQIEEAVQEQ
RRASDEIAKTILSISEGTQEIASGADDLTGFSKNMHTQSEGLLRLINQFKI
>Mature_690_residues
SIRFRISLYLALVLMAGSIAITAINAVSTYFKLTQDIKDSSSLIASRYAFEIQDFFDKALGGLRGIEFQLSHARPTREET
IESLKDLADSDPNYFGTWSVFEPGKFDSNDLQYVNKQGYDSTGRFIPYLNKSAGVDRPLVLEQVVYYENQDMSGYFYNIP
KKTGKDYIADPFAYPVSGKDVLMISVAKPLRRNGEFAGVVGMDITMKNMQEMIAPIRPYQGKGYLNLISPGGFYAANGLQ
PELVGKPIPDPEWKKLILEGSQKQEIQIYEKDNSTHFFYSFYLGNYDKKWILEVSVPYDIFWKNLSMIILETITTSLITM
VAILLVLNLIFQKLITNGINTAISFSEEISSGNLIVVNQYERKDEIGKLLLSLNQMKNNIKKIIFEIKGSSESLNSTSDK
MAESSKSFYDVAQEQASASEESSAAIEELASSAENVGRSMEKAISHMKDIDGNVILLKEQIVKINEEMKSLSFLANESQQ
QAVTGEGSMNQSTKAMDEIGDSASRINEILSIITDISEKTNLLALNAAIEAARAGEAGKGFAVVAEEISKLASQTSNSVQ
EIGQLVESTNRAVMNGTGKVKEASEILAKLRSSVDMFGVSAKTVLDSVNAQEKNTEKIHSSASSLMNFSLQIEEAVQEQR
RASDEIAKTILSISEGTQEIASGADDLTGFSKNMHTQSEGLLRLINQFKI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=376, Percent_Identity=24.468085106383, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788195, Length=265, Percent_Identity=29.0566037735849, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789453, Length=277, Percent_Identity=27.7978339350181, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI2367378, Length=279, Percent_Identity=27.2401433691756, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=343, Percent_Identity=26.2390670553936, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76384; Mature: 76252

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRFRISLYLALVLMAGSIAITAINAVSTYFKLTQDIKDSSSLIASRYAFEIQDFFDKA
CCEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLRGIEFQLSHARPTREETIESLKDLADSDPNYFGTWSVFEPGKFDSNDLQYVNKQGY
HCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHCCCC
DSTGRFIPYLNKSAGVDRPLVLEQVVYYENQDMSGYFYNIPKKTGKDYIADPFAYPVSGK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
DVLMISVAKPLRRNGEFAGVVGMDITMKNMQEMIAPIRPYQGKGYLNLISPGGFYAANGL
CEEEEEECHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCC
QPELVGKPIPDPEWKKLILEGSQKQEIQIYEKDNSTHFFYSFYLGNYDKKWILEVSVPYD
CHHHCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCEEEEEEECCHH
IFWKNLSMIILETITTSLITMVAILLVLNLIFQKLITNGINTAISFSEEISSGNLIVVNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCCEEEEEC
YERKDEIGKLLLSLNQMKNNIKKIIFEIKGSSESLNSTSDKMAESSKSFYDVAQEQASAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EESSAAIEELASSAENVGRSMEKAISHMKDIDGNVILLKEQIVKINEEMKSLSFLANESQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCH
QQAVTGEGSMNQSTKAMDEIGDSASRINEILSIITDISEKTNLLALNAAIEAARAGEAGK
HHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCC
GFAVVAEEISKLASQTSNSVQEIGQLVESTNRAVMNGTGKVKEASEILAKLRSSVDMFGV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
SAKTVLDSVNAQEKNTEKIHSSASSLMNFSLQIEEAVQEQRRASDEIAKTILSISEGTQE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IASGADDLTGFSKNMHTQSEGLLRLINQFKI
HHCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIRFRISLYLALVLMAGSIAITAINAVSTYFKLTQDIKDSSSLIASRYAFEIQDFFDKA
CEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLRGIEFQLSHARPTREETIESLKDLADSDPNYFGTWSVFEPGKFDSNDLQYVNKQGY
HCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHCCCC
DSTGRFIPYLNKSAGVDRPLVLEQVVYYENQDMSGYFYNIPKKTGKDYIADPFAYPVSGK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
DVLMISVAKPLRRNGEFAGVVGMDITMKNMQEMIAPIRPYQGKGYLNLISPGGFYAANGL
CEEEEEECHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCCC
QPELVGKPIPDPEWKKLILEGSQKQEIQIYEKDNSTHFFYSFYLGNYDKKWILEVSVPYD
CHHHCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCEEEEEEECCHH
IFWKNLSMIILETITTSLITMVAILLVLNLIFQKLITNGINTAISFSEEISSGNLIVVNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCCEEEEEC
YERKDEIGKLLLSLNQMKNNIKKIIFEIKGSSESLNSTSDKMAESSKSFYDVAQEQASAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EESSAAIEELASSAENVGRSMEKAISHMKDIDGNVILLKEQIVKINEEMKSLSFLANESQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCH
QQAVTGEGSMNQSTKAMDEIGDSASRINEILSIITDISEKTNLLALNAAIEAARAGEAGK
HHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCC
GFAVVAEEISKLASQTSNSVQEIGQLVESTNRAVMNGTGKVKEASEILAKLRSSVDMFGV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
SAKTVLDSVNAQEKNTEKIHSSASSLMNFSLQIEEAVQEQRRASDEIAKTILSISEGTQE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IASGADDLTGFSKNMHTQSEGLLRLINQFKI
HHCCCHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]