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The map label for this gene is aspB

Identifier: 45658267

GI number: 45658267

Start: 2941571

End: 2942671

Strand: Direct

Name: aspB

Synonym: LIC12422

Alternate gene names: 45658267

Gene position: 2941571-2942671 (Clockwise)

Preceding gene: 45658264

Following gene: 45658268

Centisome position: 68.77

GC content: 35.51

Gene sequence:

>1101_bases
ATGTTAGAATATGTTTTAGCCAATCGTATCCAAGGTTTGGATACTTCTGCAATTCGCAAAGCTTTTGAACTTGCAGGAAC
ACTTAAAAACCCAATCAATCTTTCGATAGGACAACCCCATTTTCCTTGTCCTTCAAATATCATAGAAGCCGGATCAAAAG
CTTTGAAAGAAGGTAAAACCGCCTACACTCTTACCGGAGGAATTCCTGAATTAAAAAGCGCACTCTCTGAAAAATACAAA
AATGAAAATGAAATTTCTTATGCAAAACCAGAAAGAATTTTAGTTACATCCGGAATCAGTTCTGCATTTCTTCTTTTATT
CAACGCATTGTTAAACGAAGGTGACGAATGTTTGGTAATAACTCCTCACTTTTTGATGTATCCAGCCTACATCAAAATTT
ACGGAGGTAAGATGAATTCAATTCACGAGTCTTTCGAACCGGAAGAGTTAAAAGAATTTGCAAATAAAAAACTCAAGATC
ATTATTTATTCCTCCCCTTCTAATCCTACTGGAAAAATTCTTTCTAAAAAACAACTGGAAGCTCTCGCAGAACTTGCAGA
AAAAACAGGAGCTTATCTAATCTCGGACGAAATTTACGAAAAATTCGATTACGATAAAAAATTTATTTCGGTCGGTTCTT
TTTATGAAAAGGCGATCACACTTTCGGGTTTTTCTAAAACATATAGTATGACGGGACTTCGTTTGGCATCTATACTGGCC
CCAGAATCCATTACAAAAACCTTAACTACTTTGCAACAATATACTCTTGTATGTGCCCCTTCCATAACTCAATGGATGGG
GATCGAAGCACTTAAAACCGATATGAGTCCCTACATAGCAGATTATAAAGAAAAGAGAGACTTTGTTTTTGAATCTTTGA
AAGATCATTACGAAATTACAAAAAGTGAAGGTGCGTTCTACTTTTTTATTAAAATCAAAGAAAAGGACGAAGACTTTATC
CTAAAAGCGGTTAAAGAGAAAGAATTGATTTTGGTACCTGGATATATTTTTACCAGTTCTAAAAATTACATCCGAATCAG
TTTTGCATCCGAATGGGAAAATCTAAAACGGGGAATCTCGGCGCTTGTTGATCTCGCCTGA

Upstream 100 bases:

>100_bases
AGTCCAACTGTCAAAAAGTGTATCGTTAAAGTATAGTTAGATCTTTAATTTTGTATAAAACATTGACTACCAGACCTATC
TTCTGTTATCAGTTATTCGT

Downstream 100 bases:

>100_bases
TTCTTTTCCTTTTTGGATAATCCTCGGTTTCGGAAGTTTAGGAGCAGCTTCCTTAGGAAGTTTTTACGTTACTTTAGGTT
TTAGAATATTAGAAACCTAT

Product: aspartate aminotransferase a

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLEYVLANRIQGLDTSAIRKAFELAGTLKNPINLSIGQPHFPCPSNIIEAGSKALKEGKTAYTLTGGIPELKSALSEKYK
NENEISYAKPERILVTSGISSAFLLLFNALLNEGDECLVITPHFLMYPAYIKIYGGKMNSIHESFEPEELKEFANKKLKI
IIYSSPSNPTGKILSKKQLEALAELAEKTGAYLISDEIYEKFDYDKKFISVGSFYEKAITLSGFSKTYSMTGLRLASILA
PESITKTLTTLQQYTLVCAPSITQWMGIEALKTDMSPYIADYKEKRDFVFESLKDHYEITKSEGAFYFFIKIKEKDEDFI
LKAVKEKELILVPGYIFTSSKNYIRISFASEWENLKRGISALVDLA

Sequences:

>Translated_366_residues
MLEYVLANRIQGLDTSAIRKAFELAGTLKNPINLSIGQPHFPCPSNIIEAGSKALKEGKTAYTLTGGIPELKSALSEKYK
NENEISYAKPERILVTSGISSAFLLLFNALLNEGDECLVITPHFLMYPAYIKIYGGKMNSIHESFEPEELKEFANKKLKI
IIYSSPSNPTGKILSKKQLEALAELAEKTGAYLISDEIYEKFDYDKKFISVGSFYEKAITLSGFSKTYSMTGLRLASILA
PESITKTLTTLQQYTLVCAPSITQWMGIEALKTDMSPYIADYKEKRDFVFESLKDHYEITKSEGAFYFFIKIKEKDEDFI
LKAVKEKELILVPGYIFTSSKNYIRISFASEWENLKRGISALVDLA
>Mature_366_residues
MLEYVLANRIQGLDTSAIRKAFELAGTLKNPINLSIGQPHFPCPSNIIEAGSKALKEGKTAYTLTGGIPELKSALSEKYK
NENEISYAKPERILVTSGISSAFLLLFNALLNEGDECLVITPHFLMYPAYIKIYGGKMNSIHESFEPEELKEFANKKLKI
IIYSSPSNPTGKILSKKQLEALAELAEKTGAYLISDEIYEKFDYDKKFISVGSFYEKAITLSGFSKTYSMTGLRLASILA
PESITKTLTTLQQYTLVCAPSITQWMGIEALKTDMSPYIADYKEKRDFVFESLKDHYEITKSEGAFYFFIKIKEKDEDFI
LKAVKEKELILVPGYIFTSSKNYIRISFASEWENLKRGISALVDLA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=297, Percent_Identity=30.976430976431, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI56713254, Length=297, Percent_Identity=30.976430976431, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI95147551, Length=405, Percent_Identity=25.679012345679, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI169881279, Length=405, Percent_Identity=25.679012345679, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI169881281, Length=388, Percent_Identity=21.9072164948454, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4507369, Length=357, Percent_Identity=25.7703081232493, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786816, Length=338, Percent_Identity=23.9644970414201, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788722, Length=360, Percent_Identity=24.7222222222222, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788627, Length=344, Percent_Identity=25.8720930232558, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788332, Length=294, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=378, Percent_Identity=26.7195767195767, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=378, Percent_Identity=26.7195767195767, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=374, Percent_Identity=25.1336898395722, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=23.342175066313, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=319, Percent_Identity=26.0188087774295, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=330, Percent_Identity=26.0606060606061, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320317, Length=398, Percent_Identity=22.8643216080402, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28573069, Length=419, Percent_Identity=25.2983293556086, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646114, Length=419, Percent_Identity=25.2983293556086, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573067, Length=419, Percent_Identity=25.2983293556086, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573065, Length=419, Percent_Identity=25.2983293556086, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI18859735, Length=371, Percent_Identity=22.911051212938, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41160; Mature: 41160

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYVLANRIQGLDTSAIRKAFELAGTLKNPINLSIGQPHFPCPSNIIEAGSKALKEGKT
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCC
AYTLTGGIPELKSALSEKYKNENEISYAKPERILVTSGISSAFLLLFNALLNEGDECLVI
EEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEE
TPHFLMYPAYIKIYGGKMNSIHESFEPEELKEFANKKLKIIIYSSPSNPTGKILSKKQLE
CCHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHH
ALAELAEKTGAYLISDEIYEKFDYDKKFISVGSFYEKAITLSGFSKTYSMTGLRLASILA
HHHHHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHC
PESITKTLTTLQQYTLVCAPSITQWMGIEALKTDMSPYIADYKEKRDFVFESLKDHYEIT
CHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEE
KSEGAFYFFIKIKEKDEDFILKAVKEKELILVPGYIFTSSKNYIRISFASEWENLKRGIS
CCCCCEEEEEEEECCCHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEHHHHHHHHHHHH
ALVDLA
HHHCCC
>Mature Secondary Structure
MLEYVLANRIQGLDTSAIRKAFELAGTLKNPINLSIGQPHFPCPSNIIEAGSKALKEGKT
CCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCC
AYTLTGGIPELKSALSEKYKNENEISYAKPERILVTSGISSAFLLLFNALLNEGDECLVI
EEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEE
TPHFLMYPAYIKIYGGKMNSIHESFEPEELKEFANKKLKIIIYSSPSNPTGKILSKKQLE
CCHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHH
ALAELAEKTGAYLISDEIYEKFDYDKKFISVGSFYEKAITLSGFSKTYSMTGLRLASILA
HHHHHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHC
PESITKTLTTLQQYTLVCAPSITQWMGIEALKTDMSPYIADYKEKRDFVFESLKDHYEIT
CHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEE
KSEGAFYFFIKIKEKDEDFILKAVKEKELILVPGYIFTSSKNYIRISFASEWENLKRGIS
CCCCCEEEEEEEECCCHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEHHHHHHHHHHHH
ALVDLA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]