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The map label for this gene is lspA

Identifier: 45658235

GI number: 45658235

Start: 2894108

End: 2894656

Strand: Reverse

Name: lspA

Synonym: LIC12389

Alternate gene names: 45658235

Gene position: 2894656-2894108 (Counterclockwise)

Preceding gene: 45658236

Following gene: 45658234

Centisome position: 67.68

GC content: 36.61

Gene sequence:

>549_bases
GTGAAATATTTTGAAAAAAGATTTTTAGACGTCTATCGCCCTATTTATTTGGGAGTTATTTTTTTAGGAATCGTATTGGA
TCTTGTGACTAAGTTTTTAGTCATTCTTTACTTTCAACCCCATCGTTATTTAGAAGTATTCGGAAGTTTTTTTAGAATGA
CTCTTACGTTTAACACCGGTTTTGTGTTTGGTGCGTTTCAGGACAACGCGATTCCTTCTTTGATCGCTACTGGAGTTGCG
ATTGTGTTTCTAATTGGTTATAGATGGAAGAATCACGATTTAGGAAATCCCTGGGGCTGGAACTTAGTGATGGCGGGAGC
TTTTGGAAATTTCTTAGATAAATTTTTTGTAAAAATTCCGGGAACAGGATTTCGTTTTGGTTTTCAACCTAATATGGGAG
AATATATCGGAGTCGTAGACTTTTTGGATTTTGATTGGCCTGACTTCCTTTTGTTTTCTAGATGGCCTGCGTTTAACGTA
GCCGATTCTTGTGTCACGATTGGTCTTACGATTTTGATCTTTACGATGAAACTAGAAGAGGAGAAATAA

Upstream 100 bases:

>100_bases
AGATTCAAAGTTGGGGATTTTTTACGTCTTCTGTGATTTTCGGATTTATACTTATCTATTCATTTTGGAAAAATAAACTT
AAAAAGAAAGGAACCTCTTT

Downstream 100 bases:

>100_bases
TTTTTTGAAGGCTCTTGATCTTCCTATCTGGAAAAAATTATTCATTCGTAAAGAAGCGAGTAATCAAGAGATCATTCGAT
TTCTCAGGGAAACTTCTGTT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKYFEKRFLDVYRPIYLGVIFLGIVLDLVTKFLVILYFQPHRYLEVFGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGVA
IVFLIGYRWKNHDLGNPWGWNLVMAGAFGNFLDKFFVKIPGTGFRFGFQPNMGEYIGVVDFLDFDWPDFLLFSRWPAFNV
ADSCVTIGLTILIFTMKLEEEK

Sequences:

>Translated_182_residues
MKYFEKRFLDVYRPIYLGVIFLGIVLDLVTKFLVILYFQPHRYLEVFGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGVA
IVFLIGYRWKNHDLGNPWGWNLVMAGAFGNFLDKFFVKIPGTGFRFGFQPNMGEYIGVVDFLDFDWPDFLLFSRWPAFNV
ADSCVTIGLTILIFTMKLEEEK
>Mature_182_residues
MKYFEKRFLDVYRPIYLGVIFLGIVLDLVTKFLVILYFQPHRYLEVFGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGVA
IVFLIGYRWKNHDLGNPWGWNLVMAGAFGNFLDKFFVKIPGTGFRFGFQPNMGEYIGVVDFLDFDWPDFLLFSRWPAFNV
ADSCVTIGLTILIFTMKLEEEK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 21088; Mature: 21088

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYFEKRFLDVYRPIYLGVIFLGIVLDLVTKFLVILYFQPHRYLEVFGSFFRMTLTFNTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCC
FVFGAFQDNAIPSLIATGVAIVFLIGYRWKNHDLGNPWGWNLVMAGAFGNFLDKFFVKIP
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCC
GTGFRFGFQPNMGEYIGVVDFLDFDWPDFLLFSRWPAFNVADSCVTIGLTILIFTMKLEE
CCCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
EK
CC
>Mature Secondary Structure
MKYFEKRFLDVYRPIYLGVIFLGIVLDLVTKFLVILYFQPHRYLEVFGSFFRMTLTFNTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCC
FVFGAFQDNAIPSLIATGVAIVFLIGYRWKNHDLGNPWGWNLVMAGAFGNFLDKFFVKIP
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCC
GTGFRFGFQPNMGEYIGVVDFLDFDWPDFLLFSRWPAFNVADSCVTIGLTILIFTMKLEE
CCCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA