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The map label for this gene is 45658176

Identifier: 45658176

GI number: 45658176

Start: 2811889

End: 2812347

Strand: Reverse

Name: 45658176

Synonym: LIC12328

Alternate gene names: NA

Gene position: 2812347-2811889 (Counterclockwise)

Preceding gene: 45658177

Following gene: 45658169

Centisome position: 65.75

GC content: 40.74

Gene sequence:

>459_bases
ATGAGACCTTTTAAAATATTAGGAATTCAACAGATTGCAGTAGGTGGGGAAGACAAAAAAAAATTAGAAACGTTTTGGGT
GGATATACTTGGGCTTGAAAAAGCGGGAACTTTTCGAAGCGAAAAAGAAAACGTAGATGAAGATATTCTCAGAATGGGTA
AGGGCGCTTATGCAGTCGAAGTAGATATTATGCAGCCGATTGATGTAAATAAAAGTCCGAAAGTACACGAACCAAAACTC
AATCATATAGGACTTTGGGTGGATGATATTCATAAAGCCGTAGAATGGTTGACCACAAAAGGGGTGCGTTTTACTCCCGG
TGGAATCCGTAAAGGTGCGGCAGGATATGACGTATGTTTTATTCATCCTAAAGGAAACGAAGAATTTCCGTATTCCTCCG
AAGGTGTACTCATAGAACTTGTACAAGCCCCCGCAGATGTAATTCAGGCACTGAGCTAG

Upstream 100 bases:

>100_bases
TCGTTTACTTGTCTCAGATTGTTTTAAAGATTGAAGTTGCCAATCTAAGGGAAATGAATTTTTTGGAACAAGATTCAATT
GACTAGTTGGAAGGAAAATC

Downstream 100 bases:

>100_bases
AAATTTTAAACGACGTCGCTTGGTGGTAACTTTGGGTTTTGTTTTTGCAGATCTAAATGAATCGATTTCTTTGTTATTTT
GATTTTTAGAATATTTTAAT

Product: putative lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: Methylmalonyl-CoA Epimerase; Glyoxalase/Bleomycin Resistance Protein/Dioxygenase

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRPFKILGIQQIAVGGEDKKKLETFWVDILGLEKAGTFRSEKENVDEDILRMGKGAYAVEVDIMQPIDVNKSPKVHEPKL
NHIGLWVDDIHKAVEWLTTKGVRFTPGGIRKGAAGYDVCFIHPKGNEEFPYSSEGVLIELVQAPADVIQALS

Sequences:

>Translated_152_residues
MRPFKILGIQQIAVGGEDKKKLETFWVDILGLEKAGTFRSEKENVDEDILRMGKGAYAVEVDIMQPIDVNKSPKVHEPKL
NHIGLWVDDIHKAVEWLTTKGVRFTPGGIRKGAAGYDVCFIHPKGNEEFPYSSEGVLIELVQAPADVIQALS
>Mature_152_residues
MRPFKILGIQQIAVGGEDKKKLETFWVDILGLEKAGTFRSEKENVDEDILRMGKGAYAVEVDIMQPIDVNKSPKVHEPKL
NHIGLWVDDIHKAVEWLTTKGVRFTPGGIRKGAAGYDVCFIHPKGNEEFPYSSEGVLIELVQAPADVIQALS

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 16885; Mature: 16885

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPFKILGIQQIAVGGEDKKKLETFWVDILGLEKAGTFRSEKENVDEDILRMGKGAYAVE
CCCEEEECEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEE
VDIMQPIDVNKSPKVHEPKLNHIGLWVDDIHKAVEWLTTKGVRFTPGGIRKGAAGYDVCF
EEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEE
IHPKGNEEFPYSSEGVLIELVQAPADVIQALS
EECCCCCCCCCCCCCEEEEEHHCCHHHHHHCC
>Mature Secondary Structure
MRPFKILGIQQIAVGGEDKKKLETFWVDILGLEKAGTFRSEKENVDEDILRMGKGAYAVE
CCCEEEECEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEE
VDIMQPIDVNKSPKVHEPKLNHIGLWVDDIHKAVEWLTTKGVRFTPGGIRKGAAGYDVCF
EEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEE
IHPKGNEEFPYSSEGVLIELVQAPADVIQALS
EECCCCCCCCCCCCCEEEEEHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA