| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
Click here to switch to the map view.
The map label for this gene is murF
Identifier: 45658139
GI number: 45658139
Start: 2763905
End: 2765305
Strand: Direct
Name: murF
Synonym: LIC12291
Alternate gene names: 45658139
Gene position: 2763905-2765305 (Clockwise)
Preceding gene: 45658137
Following gene: 45658140
Centisome position: 64.62
GC content: 36.05
Gene sequence:
>1401_bases ATGAAATCGAACTTCTACTACGATCCGGAAACCATCCGCAGAGTATTGGGATCCACATCCGAAACTTGGTATCACAAAGA ACCACTCATTACTACGATTACCACTTCATCCACAGAGGCAGAAGAAAATTCCCTTTTTGTACCTCTTTTAGGAAATAGAG ACGGACACGAATTTATCAGAGATGCAATTTCCAAAGGAGCTACTTATTTTTTAGTCGAAGAAAATCATCCGATTTATAAA AACCTTAACCTCGAAGAGAAATCCAAAGCAATCCCTGTAAAAAACACGTTAACCGCTCTCGGAAAACTCGCATCTTTTCA CAGATCCCGTTTTGATCCGATCGTAATTGCGGTCACTGGTTCCAGCGGAAAAACGACTACAAAAGAATTATTAGGAAATT GTCTTAAAAATCTAGAAGAATCTGCACTAGTCGTAACCGAAAAAAATTATAATAACGAAATTGGGCTTCCGTTTACACTT TTTAAGATTTCCGATCAGACCAGAGTTGTAGTATGCGAACTAGGAATGAACCATAAAGGAGAAATTTCAAGACTCAGTCA GATTGCTAAACCAGATTACGCCATCATAACTACAATTGGAACGGCCCATATAGAATTTTTAGAAAGTCAAAAAAACATAG CAAAAGCCAAAGGCGAAATCGTGGAAGGTTTAAAAAAAGGAGGAAAATTATTTTATCCTAATACAGGAGAATATTCTAAA ATACTAAAAAATAAAACTCGCAAACACGGAAACAAACTTGTTCTTACAAAATCTGAAAAAATTTTTTCTATTCTTCAGAA AAAATCCTCCGGATTTTTATTAGAATACAAAAACAAAAAAATCCAATGGAATCTGCCAGGTGAAAAACTTTTAGAAAACC TTTCTGTTGCTATCACATGTTTAGAAGCTATCGGTACCCCACAAGAATGGATTCAAGAAGGGATCCATTCTTTCAAGTCT TCCAATAAAAGACTAGATTTACAAAATGGCAAATATTCTGTAATCAACGATACGTATAACGCAAATTACGAATCCATGAT TTCCTCTTTGGAAGTCGCAGATCAACTCGCCGACGGAAAAGAGTTTTACGCGGTGTTAGGTGATATGAAAGAATTAGGAG AATATTCCAAAGAGTTTCATAAAAAACTTGGAAAAAAATGCTCCGAATTTCAAAACCTAAAGGGACTTTATACTTTTGGA ACAGATGCTTTTTGGATTCAAGAAGAGTTTGTTAAACGAACTTCTTCTCCCAGGTTCTCTGAACATTTTCCAGGAACACA AGAAGGACTATCAGAACTCATTCATAAATTTTTACAAACGATTCCGGAAGGTTCTATCGTATTAGCGAAGGCGTCTCGAG GAATTCAATTGGAACGTTTCGTAGAAGCGCTTCCGGTTTAA
Upstream 100 bases:
>100_bases AAAAAGATCCTTCTGTAGCCTTATGTTTGCAAGAAACTCTTTATGCTGCCAAAATTCATTTTAGAATTTTCAAAACATTC TCCCCTTACAACTTGGACCC
Downstream 100 bases:
>100_bases TACTTGCAAACAAGTAAATCTAAAGAAACATCTTCCACAGGAGAAAATGTTTGAACACAAAAGTTGCAATCATTATGGGA AGCCATTCCGATTGGGAAAC
Product: UDP-N-acetylmuramyl pentapeptide synthase
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 466; Mature: 466
Protein sequence:
>466_residues MKSNFYYDPETIRRVLGSTSETWYHKEPLITTITTSSTEAEENSLFVPLLGNRDGHEFIRDAISKGATYFLVEENHPIYK NLNLEEKSKAIPVKNTLTALGKLASFHRSRFDPIVIAVTGSSGKTTTKELLGNCLKNLEESALVVTEKNYNNEIGLPFTL FKISDQTRVVVCELGMNHKGEISRLSQIAKPDYAIITTIGTAHIEFLESQKNIAKAKGEIVEGLKKGGKLFYPNTGEYSK ILKNKTRKHGNKLVLTKSEKIFSILQKKSSGFLLEYKNKKIQWNLPGEKLLENLSVAITCLEAIGTPQEWIQEGIHSFKS SNKRLDLQNGKYSVINDTYNANYESMISSLEVADQLADGKEFYAVLGDMKELGEYSKEFHKKLGKKCSEFQNLKGLYTFG TDAFWIQEEFVKRTSSPRFSEHFPGTQEGLSELIHKFLQTIPEGSIVLAKASRGIQLERFVEALPV
Sequences:
>Translated_466_residues MKSNFYYDPETIRRVLGSTSETWYHKEPLITTITTSSTEAEENSLFVPLLGNRDGHEFIRDAISKGATYFLVEENHPIYK NLNLEEKSKAIPVKNTLTALGKLASFHRSRFDPIVIAVTGSSGKTTTKELLGNCLKNLEESALVVTEKNYNNEIGLPFTL FKISDQTRVVVCELGMNHKGEISRLSQIAKPDYAIITTIGTAHIEFLESQKNIAKAKGEIVEGLKKGGKLFYPNTGEYSK ILKNKTRKHGNKLVLTKSEKIFSILQKKSSGFLLEYKNKKIQWNLPGEKLLENLSVAITCLEAIGTPQEWIQEGIHSFKS SNKRLDLQNGKYSVINDTYNANYESMISSLEVADQLADGKEFYAVLGDMKELGEYSKEFHKKLGKKCSEFQNLKGLYTFG TDAFWIQEEFVKRTSSPRFSEHFPGTQEGLSELIHKFLQTIPEGSIVLAKASRGIQLERFVEALPV >Mature_466_residues MKSNFYYDPETIRRVLGSTSETWYHKEPLITTITTSSTEAEENSLFVPLLGNRDGHEFIRDAISKGATYFLVEENHPIYK NLNLEEKSKAIPVKNTLTALGKLASFHRSRFDPIVIAVTGSSGKTTTKELLGNCLKNLEESALVVTEKNYNNEIGLPFTL FKISDQTRVVVCELGMNHKGEISRLSQIAKPDYAIITTIGTAHIEFLESQKNIAKAKGEIVEGLKKGGKLFYPNTGEYSK ILKNKTRKHGNKLVLTKSEKIFSILQKKSSGFLLEYKNKKIQWNLPGEKLLENLSVAITCLEAIGTPQEWIQEGIHSFKS SNKRLDLQNGKYSVINDTYNANYESMISSLEVADQLADGKEFYAVLGDMKELGEYSKEFHKKLGKKCSEFQNLKGLYTFG TDAFWIQEEFVKRTSSPRFSEHFPGTQEGLSELIHKFLQTIPEGSIVLAKASRGIQLERFVEALPV
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=449, Percent_Identity=28.2850779510022, Blast_Score=134, Evalue=1e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 52489; Mature: 52489
Theoretical pI: Translated: 8.89; Mature: 8.89
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKSNFYYDPETIRRVLGSTSETWYHKEPLITTITTSSTEAEENSLFVPLLGNRDGHEFIR CCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHH DAISKGATYFLVEENHPIYKNLNLEEKSKAIPVKNTLTALGKLASFHRSRFDPIVIAVTG HHHHCCCEEEEEECCCCCEECCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC SSGKTTTKELLGNCLKNLEESALVVTEKNYNNEIGLPFTLFKISDQTRVVVCELGMNHKG CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCCC EISRLSQIAKPDYAIITTIGTAHIEFLESQKNIAKAKGEIVEGLKKGGKLFYPNTGEYSK HHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHH ILKNKTRKHGNKLVLTKSEKIFSILQKKSSGFLLEYKNKKIQWNLPGEKLLENLSVAITC HHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHH LEAIGTPQEWIQEGIHSFKSSNKRLDLQNGKYSVINDTYNANYESMISSLEVADQLADGK HHHHCCHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCH EFYAVLGDMKELGEYSKEFHKKLGKKCSEFQNLKGLYTFGTDAFWIQEEFVKRTSSPRFS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCH EHFPGTQEGLSELIHKFLQTIPEGSIVLAKASRGIQLERFVEALPV HCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCC >Mature Secondary Structure MKSNFYYDPETIRRVLGSTSETWYHKEPLITTITTSSTEAEENSLFVPLLGNRDGHEFIR CCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHH DAISKGATYFLVEENHPIYKNLNLEEKSKAIPVKNTLTALGKLASFHRSRFDPIVIAVTG HHHHCCCEEEEEECCCCCEECCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC SSGKTTTKELLGNCLKNLEESALVVTEKNYNNEIGLPFTLFKISDQTRVVVCELGMNHKG CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCCC EISRLSQIAKPDYAIITTIGTAHIEFLESQKNIAKAKGEIVEGLKKGGKLFYPNTGEYSK HHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHH ILKNKTRKHGNKLVLTKSEKIFSILQKKSSGFLLEYKNKKIQWNLPGEKLLENLSVAITC HHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHH LEAIGTPQEWIQEGIHSFKSSNKRLDLQNGKYSVINDTYNANYESMISSLEVADQLADGK HHHHCCHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCH EFYAVLGDMKELGEYSKEFHKKLGKKCSEFQNLKGLYTFGTDAFWIQEEFVKRTSSPRFS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCH EHFPGTQEGLSELIHKFLQTIPEGSIVLAKASRGIQLERFVEALPV HCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]