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The map label for this gene is hfq

Identifier: 45658094

GI number: 45658094

Start: 2709154

End: 2709411

Strand: Reverse

Name: hfq

Synonym: LIC12245

Alternate gene names: 45658094

Gene position: 2709411-2709154 (Counterclockwise)

Preceding gene: 45658095

Following gene: 45658093

Centisome position: 63.35

GC content: 39.53

Gene sequence:

>258_bases
ATGTCTGCTAAAAACAATATACAGGACCAACTCTTAAACACTGCCCGGAAGGATAAATTGGATCTTACGATTTATCTACT
GAACGGGGTTCCCTTGAAAGGCAAAGTGGTGAGCTTCGATAATTTTACGATTGTGCTCGAACAAGAAAATAAACAGAGCC
TCGTTTATAAACACGCTATTTCTACGATCATTCCCGCCAAGATTATCAAGCTATATACCGAGGAAGCAAAAGACAATAAA
GACGCAGCTCAAGGATAA

Upstream 100 bases:

>100_bases
CAGATCACTTGGTTTCGAAAAGAAAACTACATCCAAGCTATGGATCGGTCCGAGGCGCTGGAACGGATCAAACATATAAA
ATAAACGGAAATAAAAAAAG

Downstream 100 bases:

>100_bases
TGCGATTTTGGATTAAGTTATTTTGGGTTCTCGTTTTTGGGACCCTCGCGGCTTTTTTTTATTTTTGTATTCATACTCTC
AAAGAAAGAGAGTCGCTTCT

Product: host factor-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MSAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAISTIIPAKIIKLYTEEAKDNK
DAAQG

Sequences:

>Translated_85_residues
MSAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAISTIIPAKIIKLYTEEAKDNK
DAAQG
>Mature_84_residues
SAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAISTIIPAKIIKLYTEEAKDNKD
AAQG

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=76, Percent_Identity=39.4736842105263, Blast_Score=72, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_LEPIC (Q72Q67)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_002180.1
- ProteinModelPortal:   Q72Q67
- SMR:   Q72Q67
- GeneID:   2770659
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC12245
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- ProtClustDB:   CLSK573953
- BioCyc:   LINT267671:LIC_12245-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9532; Mature: 9401

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAI
CCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHH
STIIPAKIIKLYTEEAKDNKDAAQG
HHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAI
CCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHH
STIIPAKIIKLYTEEAKDNKDAAQG
HHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA