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The map label for this gene is eryC1 [H]

Identifier: 45657978

GI number: 45657978

Start: 2574059

End: 2575150

Strand: Reverse

Name: eryC1 [H]

Synonym: LIC12130

Alternate gene names: 45657978

Gene position: 2575150-2574059 (Counterclockwise)

Preceding gene: 45657979

Following gene: 45657977

Centisome position: 60.21

GC content: 32.6

Gene sequence:

>1092_bases
ATGATTGAATATGAAAATTTACGTTTAGCGAATGAACGCTTTTTTGACGAGTATAAAACTAAACTTTTAGAAACCATAGA
AAGCGGATGGTATATATTAGGAAAAGAAGTTTCTAACTTTGAAAGTCAATTTGCAGAATACAATGGAAATAGATATTGTA
TTGGGGTAGGAAATGGTCTAGATGCGTTGATACTCGCCTTAAAGGCGTTAGGTCTAGAAAAGAATTCTGAAATTATAGTT
CCTTCAAATACGTATATAGCTTCTATATTAGCAATTTTGCATGCAGGTTTGAAACCCGTTTTAGTTGAACCAGATATTCG
GACCTATAACATTGATCCCCAAAAGATAGAGGAAAAAATAAATTTTAAAACAAAAGGGATTTTGATCGTACATCTGTATG
GTAAACCTTGTGAAATGGATTCTATTTTAAAGATAAAAGAAAAAAATAATCTGTTTCTAGTGGAAGATTGTGCGCAGTCT
CATGGGGCCTTGTATAAGAATAAAAAAACGGGAACGTTTGGAGAAATGAGTGGATTCAGTTTTTACCCCACTAAAAATTT
AGGAGCTCTTGGGGATGCGGGTGCGGTTGTAACTGATAATGATTTATATCACGACGAGATTCGGAAATTAAGAAATTATG
GTTCTTCAATCAAGTATAAAAATGATTTGGTCGGATATAACTCTCGTTTAGATGAATTACAAGCAACAATTTTAAGTATC
AAGCTGAAACATTTGGATGTAATGAACGAGCATAAAAGAAGTTTGGCGAAAATTTATCTAGAAAATCTAAAAGAAGATTT
TATAAAACCAATAGTCGACGAAGAAGTTTACGACGTATATCATATCTTTAATATTCGTCATACAAAACGTGACGATTTGC
GAGACTATCTGTTAAAAAATGGCGTAAAAACAGAAGTTCATTACCCAATTCCTCCTCATAAACAAATAGCGATGAAGGAC
GTAATCTTATACGCAGAGGGCGAGTTTGCGATCTCAGAAGAGATTCATCGTACAACTCTTAGTCTTCCTATTTCAACTTT
TCATACAGAAGAAGATATTTATAAAATTGTAGAAATTATGAATAGATTTTAA

Upstream 100 bases:

>100_bases
TGTATCCTTCTTGTTGCCGCTTCGGATTATTATAGAGAAGACGATTACATAAGAAATTATTCTGATTTTATCAGGCTGGC
TGGTTGAAAAAAAATTAAAT

Downstream 100 bases:

>100_bases
AGAAAGATTTTCATTTATCAAAAATAAAAATTTCTTCATATAAGAATTTCATAAAAACTAAATGCTTTTATAAAAATTTT
ACTGATATTATTAGACACAT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MIEYENLRLANERFFDEYKTKLLETIESGWYILGKEVSNFESQFAEYNGNRYCIGVGNGLDALILALKALGLEKNSEIIV
PSNTYIASILAILHAGLKPVLVEPDIRTYNIDPQKIEEKINFKTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS
HGALYKNKKTGTFGEMSGFSFYPTKNLGALGDAGAVVTDNDLYHDEIRKLRNYGSSIKYKNDLVGYNSRLDELQATILSI
KLKHLDVMNEHKRSLAKIYLENLKEDFIKPIVDEEVYDVYHIFNIRHTKRDDLRDYLLKNGVKTEVHYPIPPHKQIAMKD
VILYAEGEFAISEEIHRTTLSLPISTFHTEEDIYKIVEIMNRF

Sequences:

>Translated_363_residues
MIEYENLRLANERFFDEYKTKLLETIESGWYILGKEVSNFESQFAEYNGNRYCIGVGNGLDALILALKALGLEKNSEIIV
PSNTYIASILAILHAGLKPVLVEPDIRTYNIDPQKIEEKINFKTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS
HGALYKNKKTGTFGEMSGFSFYPTKNLGALGDAGAVVTDNDLYHDEIRKLRNYGSSIKYKNDLVGYNSRLDELQATILSI
KLKHLDVMNEHKRSLAKIYLENLKEDFIKPIVDEEVYDVYHIFNIRHTKRDDLRDYLLKNGVKTEVHYPIPPHKQIAMKD
VILYAEGEFAISEEIHRTTLSLPISTFHTEEDIYKIVEIMNRF
>Mature_363_residues
MIEYENLRLANERFFDEYKTKLLETIESGWYILGKEVSNFESQFAEYNGNRYCIGVGNGLDALILALKALGLEKNSEIIV
PSNTYIASILAILHAGLKPVLVEPDIRTYNIDPQKIEEKINFKTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS
HGALYKNKKTGTFGEMSGFSFYPTKNLGALGDAGAVVTDNDLYHDEIRKLRNYGSSIKYKNDLVGYNSRLDELQATILSI
KLKHLDVMNEHKRSLAKIYLENLKEDFIKPIVDEEVYDVYHIFNIRHTKRDDLRDYLLKNGVKTEVHYPIPPHKQIAMKD
VILYAEGEFAISEEIHRTTLSLPISTFHTEEDIYKIVEIMNRF

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=305, Percent_Identity=29.1803278688525, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI2367285, Length=269, Percent_Identity=31.5985130111524, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41752; Mature: 41752

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYENLRLANERFFDEYKTKLLETIESGWYILGKEVSNFESQFAEYNGNRYCIGVGNGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCH
DALILALKALGLEKNSEIIVPSNTYIASILAILHAGLKPVLVEPDIRTYNIDPQKIEEKI
HHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCEEECCCHHHHHHHH
NFKTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQSHGALYKNKKTGTFGEMSGFS
CEEECCEEEEEECCCCCCCCHHEEEECCCCEEEEEHHHHHCCCEEECCCCCCCCCCCCCE
FYPTKNLGALGDAGAVVTDNDLYHDEIRKLRNYGSSIKYKNDLVGYNSRLDELQATILSI
ECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KLKHLDVMNEHKRSLAKIYLENLKEDFIKPIVDEEVYDVYHIFNIRHTKRDDLRDYLLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GVKTEVHYPIPPHKQIAMKDVILYAEGEFAISEEIHRTTLSLPISTFHTEEDIYKIVEIM
CCCCEEECCCCCCHHHHEEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHH
NRF
HCC
>Mature Secondary Structure
MIEYENLRLANERFFDEYKTKLLETIESGWYILGKEVSNFESQFAEYNGNRYCIGVGNGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCH
DALILALKALGLEKNSEIIVPSNTYIASILAILHAGLKPVLVEPDIRTYNIDPQKIEEKI
HHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCEEECCCHHHHHHHH
NFKTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQSHGALYKNKKTGTFGEMSGFS
CEEECCEEEEEECCCCCCCCHHEEEECCCCEEEEEHHHHHCCCEEECCCCCCCCCCCCCE
FYPTKNLGALGDAGAVVTDNDLYHDEIRKLRNYGSSIKYKNDLVGYNSRLDELQATILSI
ECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KLKHLDVMNEHKRSLAKIYLENLKEDFIKPIVDEEVYDVYHIFNIRHTKRDDLRDYLLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GVKTEVHYPIPPHKQIAMKDVILYAEGEFAISEEIHRTTLSLPISTFHTEEDIYKIVEIM
CCCCEEECCCCCCHHHHEEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHH
NRF
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]