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The map label for this gene is rfbC

Identifier: 45657974

GI number: 45657974

Start: 2568558

End: 2569118

Strand: Reverse

Name: rfbC

Synonym: LIC12126

Alternate gene names: 45657974

Gene position: 2569118-2568558 (Counterclockwise)

Preceding gene: 45657975

Following gene: 45657973

Centisome position: 60.07

GC content: 36.72

Gene sequence:

>561_bases
ATGCAATTTAAAAAATTTCAGATAGAAGGTCCAGTTTTAATTGAACCTAAAGTTTTTGGAGATGAAAGAGGTTTTTTTTT
GGAAACCTTTAAGGCATCTATTTTCGAAAAAGAAAACATACCATTTCAATTTTCCCAAGACAATCATTCTAGATCTTCTC
GAGGGGTATTGAGGGGGATGCATCTGCAAATTCCTCCTTACGATCAAGGAAAGTTAGTCCGAGTAGTGAGAGGTAAGGTG
ATAGATGTGGTGGTAGACGTTAGGGTAGGTTCCCCCAATTATGGAAAATGGCTTTCCGTGGAATTATCTGAAGAAAATAA
AAATATATTTTGGGTTCCTCCTGGATTTGCTCATGGATTTTTAACCTTAGAAGATAAAACAGATTTTTTATATAAAGTGA
CCGGAGAATACAGTCCTCAGAATGAGGTAGGAATTCGTTGGGATGATCCTGCGTTAGGTATTCCTTGGAAGACATGGTTG
TCTGATTCTGAATTTATAGTATCTCAGAGGGACCAAGTGACTCCTTTTTTTGCAGACTTTAAAAGTCCATTCGTATATTA
G

Upstream 100 bases:

>100_bases
TTAGAAATAATAAAACAGAGAACTCTTATTCTTTATGATTACGAATTTTAGTTTATTAGAAAAATTTAATTTATATTAAT
TGAACGTCAGTTGAAGTATT

Downstream 100 bases:

>100_bases
AATATGATTTATTATACTGGAAAAAACGGTCAGTTAGGTTGGGAATTGGCCGAAAGATTTAAATCTAATGGATTGGAAGC
AGTAGGATTTGGTAGGGAAG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MQFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQFSQDNHSRSSRGVLRGMHLQIPPYDQGKLVRVVRGKV
IDVVVDVRVGSPNYGKWLSVELSEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWL
SDSEFIVSQRDQVTPFFADFKSPFVY

Sequences:

>Translated_186_residues
MQFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQFSQDNHSRSSRGVLRGMHLQIPPYDQGKLVRVVRGKV
IDVVVDVRVGSPNYGKWLSVELSEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWL
SDSEFIVSQRDQVTPFFADFKSPFVY
>Mature_186_residues
MQFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQFSQDNHSRSSRGVLRGMHLQIPPYDQGKLVRVVRGKV
IDVVVDVRVGSPNYGKWLSVELSEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWL
SDSEFIVSQRDQVTPFFADFKSPFVY

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=173, Percent_Identity=47.9768786127168, Blast_Score=166, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17550412, Length=189, Percent_Identity=43.9153439153439, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21515; Mature: 21515

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQFSQDNHSRSSRGVLRGM
CCCEEEEECCCEEECCEEECCCCCEEEEEHHHHHEECCCCCEEECCCCCCCCCCCEEECE
HLQIPPYDQGKLVRVVRGKVIDVVVDVRVGSPNYGKWLSVELSEENKNIFWVPPGFAHGF
EEECCCCCCCCEEEEECCEEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCEE
LTLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWLSDSEFIVSQRDQVTPFFADF
EEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHCCCCEEEECCCCCCCCHHHHC
KSPFVY
CCCCCC
>Mature Secondary Structure
MQFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQFSQDNHSRSSRGVLRGM
CCCEEEEECCCEEECCEEECCCCCEEEEEHHHHHEECCCCCEEECCCCCCCCCCCEEECE
HLQIPPYDQGKLVRVVRGKVIDVVVDVRVGSPNYGKWLSVELSEENKNIFWVPPGFAHGF
EEECCCCCCCCEEEEECCEEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCEE
LTLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWLSDSEFIVSQRDQVTPFFADF
EEEECCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHCCCCEEEECCCCCCCCHHHHC
KSPFVY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]