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The map label for this gene is gapA

Identifier: 45657938

GI number: 45657938

Start: 2529145

End: 2530152

Strand: Direct

Name: gapA

Synonym: LIC12090

Alternate gene names: 45657938

Gene position: 2529145-2530152 (Clockwise)

Preceding gene: 45657936

Following gene: 45657939

Centisome position: 59.13

GC content: 40.58

Gene sequence:

>1008_bases
ATGACCAGAATAGCCATCAACGGATTTGGAAGAATTGGAAGACTCGTTTTCCGTGCAGGAATCAAAGACCCCAATTTAGA
ATTTGTCGCCATCAATGATTTAGTGACTCCTGATAACCTGGCCTACTTACTCAAATACGATTCCACTCACGGAAGATTTC
AAGGAACCGTTGAACATACTGAAAAAGAACTAATCGTAGACGGAAAAAAAATACTATGTGTTTCCGAAAGAGATCCTGAA
AAACTTCCTTGGAAAGATCTCAAAGTAGATTACGTAATAGAATCTACCGGTCTTTTTACAGATAGAGTCGGCGCCGAAAA
ACATATCAAAGCTGGCGCTAAAAAAGTAGTGATATCTGCTCCTGCAAAGGACAAAGATATTCCTACTTTCGTCATGGGTG
TAAACAACGAAAAATACAATCCTTCTAATGATCACATTGTATCTAACGCTTCCTGCACTACCAACTGTCTCGCACCAATC
GTAAAAGTGGTTTTGGACAACTGGGGAATCGAAGAAGGTCTAATGACTACAATTCATGCAACCACTGCTACTCAACCTAC
CGTAGACGGACCTTCTAAAAAAGATTTCCGTGGAGGAAGAGGAGCCATGCAAAATATCATTCCTGCGTCTACCGGTGCCG
CAAAAGCGGTTGGGCTTTGTATCCCAGAAGTCAACGGTAAACTGACTGGAATGTCGTTTCGAGTTCCTACTCCTGACGTT
TCCGTAGTAGACTTAACCGTTAGAACTACAAAAGAAACTTCTCTGAAAGAAATTTCCGCTAAGATGAAAGCTGCTTCCGA
AGGTGCTATGAAAGGAATTCTTGGTTATACCGAAGATATGGTAGTTTCTAACGATTTCGTAAGTTCTACACTTTCTTCTA
TCTTTGATATGGACGCCTGTATCGAACTCAATTCTAGATTTTTTAAATTAGTCTCCTGGTATGATAACGAAATGGGTTAC
TCCAACCGGGTTTTAGATCTGATCCGCTATATGGCGAAAAAAGGTTAA

Upstream 100 bases:

>100_bases
TGTCCTCAAAGGACGATAAATCTTGCGACTTTGGACCTTTTATAAAAGAAAATTTGAATTTTAGGACAAGCCGTAAATCT
AAAACAACGAAGGGAAAAAA

Downstream 100 bases:

>100_bases
TTCATGGAATTACCTAGACTTGAAAATGTAGATCTCTCAGGAAAGAGAGTTTTCCTGAGAGTAGATTTTAACGTTCCAGT
AGAAAATGGAAAAGTTACAG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTRIAINGFGRIGRLVFRAGIKDPNLEFVAINDLVTPDNLAYLLKYDSTHGRFQGTVEHTEKELIVDGKKILCVSERDPE
KLPWKDLKVDYVIESTGLFTDRVGAEKHIKAGAKKVVISAPAKDKDIPTFVMGVNNEKYNPSNDHIVSNASCTTNCLAPI
VKVVLDNWGIEEGLMTTIHATTATQPTVDGPSKKDFRGGRGAMQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
SVVDLTVRTTKETSLKEISAKMKAASEGAMKGILGYTEDMVVSNDFVSSTLSSIFDMDACIELNSRFFKLVSWYDNEMGY
SNRVLDLIRYMAKKG

Sequences:

>Translated_335_residues
MTRIAINGFGRIGRLVFRAGIKDPNLEFVAINDLVTPDNLAYLLKYDSTHGRFQGTVEHTEKELIVDGKKILCVSERDPE
KLPWKDLKVDYVIESTGLFTDRVGAEKHIKAGAKKVVISAPAKDKDIPTFVMGVNNEKYNPSNDHIVSNASCTTNCLAPI
VKVVLDNWGIEEGLMTTIHATTATQPTVDGPSKKDFRGGRGAMQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
SVVDLTVRTTKETSLKEISAKMKAASEGAMKGILGYTEDMVVSNDFVSSTLSSIFDMDACIELNSRFFKLVSWYDNEMGY
SNRVLDLIRYMAKKG
>Mature_334_residues
TRIAINGFGRIGRLVFRAGIKDPNLEFVAINDLVTPDNLAYLLKYDSTHGRFQGTVEHTEKELIVDGKKILCVSERDPEK
LPWKDLKVDYVIESTGLFTDRVGAEKHIKAGAKKVVISAPAKDKDIPTFVMGVNNEKYNPSNDHIVSNASCTTNCLAPIV
KVVLDNWGIEEGLMTTIHATTATQPTVDGPSKKDFRGGRGAMQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDVS
VVDLTVRTTKETSLKEISAKMKAASEGAMKGILGYTEDMVVSNDFVSSTLSSIFDMDACIELNSRFFKLVSWYDNEMGYS
NRVLDLIRYMAKKG

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=59.7597597597598, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=58.3586626139818, Blast_Score=391, Evalue=1e-109,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=64.6525679758308, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=40.2402402402402, Blast_Score=245, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=63.6094674556213, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=63.3136094674556, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=63.4502923976608, Blast_Score=422, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=63.7982195845697, Blast_Score=422, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=63.7724550898204, Blast_Score=427, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=62.2754491017964, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=62.874251497006, Blast_Score=423, Evalue=1e-119,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=61.4925373134328, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=61.4925373134328, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=61.4925373134328, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=61.4925373134328, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=57.0996978851964, Blast_Score=370, Evalue=1e-102,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36649; Mature: 36517

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIAINGFGRIGRLVFRAGIKDPNLEFVAINDLVTPDNLAYLLKYDSTHGRFQGTVEHT
CCEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCEEECCHHHC
EKELIVDGKKILCVSERDPEKLPWKDLKVDYVIESTGLFTDRVGAEKHIKAGAKKVVISA
CCEEEECCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHCCCCHHHHHCCCCEEEEEC
PAKDKDIPTFVMGVNNEKYNPSNDHIVSNASCTTNCLAPIVKVVLDNWGIEEGLMTTIHA
CCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
TTATQPTVDGPSKKDFRGGRGAMQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCC
SVVDLTVRTTKETSLKEISAKMKAASEGAMKGILGYTEDMVVSNDFVSSTLSSIFDMDAC
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCHHHHHHHHHHHCCHHH
IELNSRFFKLVSWYDNEMGYSNRVLDLIRYMAKKG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRIAINGFGRIGRLVFRAGIKDPNLEFVAINDLVTPDNLAYLLKYDSTHGRFQGTVEHT
CEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCEEECCHHHC
EKELIVDGKKILCVSERDPEKLPWKDLKVDYVIESTGLFTDRVGAEKHIKAGAKKVVISA
CCEEEECCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHCCCCHHHHHCCCCEEEEEC
PAKDKDIPTFVMGVNNEKYNPSNDHIVSNASCTTNCLAPIVKVVLDNWGIEEGLMTTIHA
CCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
TTATQPTVDGPSKKDFRGGRGAMQNIIPASTGAAKAVGLCIPEVNGKLTGMSFRVPTPDV
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCC
SVVDLTVRTTKETSLKEISAKMKAASEGAMKGILGYTEDMVVSNDFVSSTLSSIFDMDAC
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCHHHHHHHHHHHCCHHH
IELNSRFFKLVSWYDNEMGYSNRVLDLIRYMAKKG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]