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The map label for this gene is pgk

Identifier: 45657939

GI number: 45657939

Start: 2530156

End: 2531346

Strand: Direct

Name: pgk

Synonym: LIC12091

Alternate gene names: 45657939

Gene position: 2530156-2531346 (Clockwise)

Preceding gene: 45657938

Following gene: 45657942

Centisome position: 59.15

GC content: 40.05

Gene sequence:

>1191_bases
ATGGAATTACCTAGACTTGAAAATGTAGATCTCTCAGGAAAGAGAGTTTTCCTGAGAGTAGATTTTAACGTTCCAGTAGA
AAATGGAAAAGTTACAGACAAAACTAGAATTGAAAAGACTCTTCCTACAATCGAACTTCTGATTAAAAAAGGCGCAAGGA
TAATTATTGCGAGTCACTTAGGAAGACCCAAAGGACAAGTAAATCCTGAATTTTCTTTGGCGCCAGTAGTTGAAACTTTC
CAAAGTCTTGTAAAATCTAAGGTTTATTTTTCTAAGACAGTAATCGGAGAAGACGCGATTAAACTTTCTAAAGAACTTAA
AAACGGCGAAATTTTAGTAATTGAAAACGTTCGTTTTCATAAAGAAGAAGAGGAAAATGATCCTGGTTTTTCCAAAAAAC
TTGCTGCGTTAGCCGACATCTATGTGAACGACGCTTTTGGGGCAGCCCACAGAGCGCACTCTTCCACCGAAGGAATTGCA
CGTCTACTTCCTGCATATGCAGGTCTTCTAATGCACAAAGAGATCTTAGAACTTTCTGCGCTTCTGCATAAACCGGCTCG
TCCATTTGTGGCGATCATAGGAGGTTCCAAAGTTTCCACTAAGATCAAGGTCCTAACCAATCTATTCGACAAGGTAAATC
ATCTTCTCATTGGTGGTGGAATGGCTTATACGTTTTTAAAGTCCAGAGCGATCCCTATTGGAAATTCACTCGTGGAAAAA
GAATTCGAAGTTCAAGCCTTTCAGTTAATCGAAAAAGCAGGCGTCGCTGGTATCGATTTACAACTTCCGGTAGATCACAT
CATTGGAGATCAGTTTAACGAAAAGGCAAAGACCAAGTCCGTAGATAAGATGGGAATTTTAGACGGTTGGATGGGAATGG
ATATAGGCTCTAAAACGGTTTCTAACTACGAAAAGATTATTAAAAACGCTGGTACGATTTTTTGGAACGGGCCAATGGGT
GTTTTTGAAATGGATAAATTTGCGAGTGGGACTATGGCAATCGCCAAAGCAGTCGCTAAATCCAAGGCAAAAACAGTTGT
AGGTGGAGGAGATTCCATCGCTGCAATCAACAAAGCTAGAGTTGCAGATAAAATTACTCATATCTCAACTGGCGGTGGAG
CTTCCCTCGAATTTATGGAAGGTAGAAAACTTCCAGGAGTAGAAGCCCTTAAGAAAAAAACTTCCGAGTAA

Upstream 100 bases:

>100_bases
TTCTAGATTTTTTAAATTAGTCTCCTGGTATGATAACGAAATGGGTTACTCCAACCGGGTTTTAGATCTGATCCGCTATA
TGGCGAAAAAAGGTTAATTC

Downstream 100 bases:

>100_bases
GTTCGAATTCAAAGTGTTTTTACAATCAAACCTTACAGCCGGGCATCCGCCAATCTCAGCCACCTAGGAGCAACAGTGTT
GCTCCGAAGCGAGATTAGGA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MELPRLENVDLSGKRVFLRVDFNVPVENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQVNPEFSLAPVVETF
QSLVKSKVYFSKTVIGEDAIKLSKELKNGEILVIENVRFHKEEEENDPGFSKKLAALADIYVNDAFGAAHRAHSSTEGIA
RLLPAYAGLLMHKEILELSALLHKPARPFVAIIGGSKVSTKIKVLTNLFDKVNHLLIGGGMAYTFLKSRAIPIGNSLVEK
EFEVQAFQLIEKAGVAGIDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMG
VFEMDKFASGTMAIAKAVAKSKAKTVVGGGDSIAAINKARVADKITHISTGGGASLEFMEGRKLPGVEALKKKTSE

Sequences:

>Translated_396_residues
MELPRLENVDLSGKRVFLRVDFNVPVENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQVNPEFSLAPVVETF
QSLVKSKVYFSKTVIGEDAIKLSKELKNGEILVIENVRFHKEEEENDPGFSKKLAALADIYVNDAFGAAHRAHSSTEGIA
RLLPAYAGLLMHKEILELSALLHKPARPFVAIIGGSKVSTKIKVLTNLFDKVNHLLIGGGMAYTFLKSRAIPIGNSLVEK
EFEVQAFQLIEKAGVAGIDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMG
VFEMDKFASGTMAIAKAVAKSKAKTVVGGGDSIAAINKARVADKITHISTGGGASLEFMEGRKLPGVEALKKKTSE
>Mature_396_residues
MELPRLENVDLSGKRVFLRVDFNVPVENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQVNPEFSLAPVVETF
QSLVKSKVYFSKTVIGEDAIKLSKELKNGEILVIENVRFHKEEEENDPGFSKKLAALADIYVNDAFGAAHRAHSSTEGIA
RLLPAYAGLLMHKEILELSALLHKPARPFVAIIGGSKVSTKIKVLTNLFDKVNHLLIGGGMAYTFLKSRAIPIGNSLVEK
EFEVQAFQLIEKAGVAGIDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMG
VFEMDKFASGTMAIAKAVAKSKAKTVVGGGDSIAAINKARVADKITHISTGGGASLEFMEGRKLPGVEALKKKTSE

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=408, Percent_Identity=43.8725490196078, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI4505763, Length=408, Percent_Identity=43.1372549019608, Blast_Score=328, Evalue=6e-90,
Organism=Escherichia coli, GI1789294, Length=397, Percent_Identity=44.3324937027708, Blast_Score=321, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17508823, Length=406, Percent_Identity=44.0886699507389, Blast_Score=344, Evalue=6e-95,
Organism=Saccharomyces cerevisiae, GI6319857, Length=408, Percent_Identity=44.3627450980392, Blast_Score=329, Evalue=5e-91,
Organism=Drosophila melanogaster, GI17136394, Length=406, Percent_Identity=44.5812807881773, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24581203, Length=407, Percent_Identity=42.2604422604423, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 43003; Mature: 43003

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPRLENVDLSGKRVFLRVDFNVPVENGKVTDKTRIEKTLPTIELLIKKGARIIIASHL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
GRPKGQVNPEFSLAPVVETFQSLVKSKVYFSKTVIGEDAIKLSKELKNGEILVIENVRFH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCEEC
KEEEENDPGFSKKLAALADIYVNDAFGAAHRAHSSTEGIARLLPAYAGLLMHKEILELSA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLHKPARPFVAIIGGSKVSTKIKVLTNLFDKVNHLLIGGGMAYTFLKSRAIPIGNSLVEK
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCHHHHH
EFEVQAFQLIEKAGVAGIDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTV
HHHHHHHHHHHHCCCCCEEEECCHHHHHCCCHHHHHHHCCCHHHHCCCCCCCCCCCHHHH
SNYEKIIKNAGTIFWNGPMGVFEMDKFASGTMAIAKAVAKSKAKTVVGGGDSIAAINKAR
HHHHHHHHCCCEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHH
VADKITHISTGGGASLEFMEGRKLPGVEALKKKTSE
HHHHHHEEECCCCCEEEEECCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MELPRLENVDLSGKRVFLRVDFNVPVENGKVTDKTRIEKTLPTIELLIKKGARIIIASHL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
GRPKGQVNPEFSLAPVVETFQSLVKSKVYFSKTVIGEDAIKLSKELKNGEILVIENVRFH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECCEEC
KEEEENDPGFSKKLAALADIYVNDAFGAAHRAHSSTEGIARLLPAYAGLLMHKEILELSA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLHKPARPFVAIIGGSKVSTKIKVLTNLFDKVNHLLIGGGMAYTFLKSRAIPIGNSLVEK
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCHHHHH
EFEVQAFQLIEKAGVAGIDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTV
HHHHHHHHHHHHCCCCCEEEECCHHHHHCCCHHHHHHHCCCHHHHCCCCCCCCCCCHHHH
SNYEKIIKNAGTIFWNGPMGVFEMDKFASGTMAIAKAVAKSKAKTVVGGGDSIAAINKAR
HHHHHHHHCCCEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHH
VADKITHISTGGGASLEFMEGRKLPGVEALKKKTSE
HHHHHHEEECCCCCEEEEECCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA