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The map label for this gene is sipA

Identifier: 45657934

GI number: 45657934

Start: 2524784

End: 2525344

Strand: Direct

Name: sipA

Synonym: LIC12086

Alternate gene names: 45657934

Gene position: 2524784-2525344 (Clockwise)

Preceding gene: 45657927

Following gene: 45657935

Centisome position: 59.03

GC content: 37.08

Gene sequence:

>561_bases
ATGAGTAGAAGTTCTTCCAACCAAGAAAAAGAAAAAAGGGAAAAAATAAAATCCATTCTCAAACAAGCCGGAATCGGACT
TTTGATCGGTTTAAGTATTGCGATTTTGATTCGATCCTTTCTTTTTTTTCCATTTACGTTGGAAACCAAAGACATGCTTC
CTACTTATTCCCCTGGAAAAAGAATTTATTTCCATAGGTTTGTAAATCGTTCCAATCTCTATCTTGGAGATTTAGTTTTA
GTCAAACATCCAACTCAAGAAGGTAAGGTAGTTTTTTCCAGGATCTCCGGAAAACCAGGAGACACAGTTCAAATGAAAAA
TAAGATCTTGTATCGTAATAATCATCCAGAAGATATTTCTGGTGTTGGGAGTGGCTTTACACTTCAGTTCGAAGATAAAC
GAGGAGCATTTCCCTCCAGTTTTTCTGGCAGAGACAACGGAGAACCTTTGATTCTTAAAGACCGAGATTATTTTCTTCTC
TGCGACAACCGAGATTCTTGCTCCGACTCCAGAGATTTTGGTCCAATTCCTATAGAAAACATATTAGGAAAAGCGTTCTA
A

Upstream 100 bases:

>100_bases
CTCTCTTTCTTCCTACAGATCTTTCTTTTAGAGACTTCAAAACAAGTCTAAAAAAAAGATTTTCTTTTGACCCAATTTCA
ATTGGAAAAAAAATGCACGC

Downstream 100 bases:

>100_bases
ACTTTTATTTCAGACTTTCTTTTTTTACTTTTCGATTTTTATTTTCATCTTTTTCGTGCCGATATTATAAATTCAAATAT
TCTAATTTACTATTTGACAC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSRSSSNQEKEKREKIKSILKQAGIGLLIGLSIAILIRSFLFFPFTLETKDMLPTYSPGKRIYFHRFVNRSNLYLGDLVL
VKHPTQEGKVVFSRISGKPGDTVQMKNKILYRNNHPEDISGVGSGFTLQFEDKRGAFPSSFSGRDNGEPLILKDRDYFLL
CDNRDSCSDSRDFGPIPIENILGKAF

Sequences:

>Translated_186_residues
MSRSSSNQEKEKREKIKSILKQAGIGLLIGLSIAILIRSFLFFPFTLETKDMLPTYSPGKRIYFHRFVNRSNLYLGDLVL
VKHPTQEGKVVFSRISGKPGDTVQMKNKILYRNNHPEDISGVGSGFTLQFEDKRGAFPSSFSGRDNGEPLILKDRDYFLL
CDNRDSCSDSRDFGPIPIENILGKAF
>Mature_185_residues
SRSSSNQEKEKREKIKSILKQAGIGLLIGLSIAILIRSFLFFPFTLETKDMLPTYSPGKRIYFHRFVNRSNLYLGDLVLV
KHPTQEGKVVFSRISGKPGDTVQMKNKILYRNNHPEDISGVGSGFTLQFEDKRGAFPSSFSGRDNGEPLILKDRDYFLLC
DNRDSCSDSRDFGPIPIENILGKAF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21040; Mature: 20909

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSSSNQEKEKREKIKSILKQAGIGLLIGLSIAILIRSFLFFPFTLETKDMLPTYSPGK
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEECHHHCCCCCCCCC
RIYFHRFVNRSNLYLGDLVLVKHPTQEGKVVFSRISGKPGDTVQMKNKILYRNNHPEDIS
EEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCEEEECCEEEECCCCCCCCC
GVGSGFTLQFEDKRGAFPSSFSGRDNGEPLILKDRDYFLLCDNRDSCSDSRDFGPIPIEN
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCHHH
ILGKAF
HHCCCC
>Mature Secondary Structure 
SRSSSNQEKEKREKIKSILKQAGIGLLIGLSIAILIRSFLFFPFTLETKDMLPTYSPGK
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEECHHHCCCCCCCCC
RIYFHRFVNRSNLYLGDLVLVKHPTQEGKVVFSRISGKPGDTVQMKNKILYRNNHPEDIS
EEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCEEEECCEEEECCCCCCCCC
GVGSGFTLQFEDKRGAFPSSFSGRDNGEPLILKDRDYFLLCDNRDSCSDSRDFGPIPIEN
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCHHH
ILGKAF
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 9823656 [H]