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The map label for this gene is 45657870

Identifier: 45657870

GI number: 45657870

Start: 2431140

End: 2432747

Strand: Direct

Name: 45657870

Synonym: LIC12018

Alternate gene names: NA

Gene position: 2431140-2432747 (Clockwise)

Preceding gene: 45657868

Following gene: 45657871

Centisome position: 56.84

GC content: 38.0

Gene sequence:

>1608_bases
TTGCAAGTAAACATCATGCAAAAGGAAGCTCCAAAAGAAAGTTGGAAATCTAGAACCGGACTCATCCTTACTGTGGCAAG
TGGTGCAATCGGACTCGGAAATTTTATCCGTTTCCCTGGCCAAGCAGTTGCTAACGGTGGCGGAGCCTTTATGGTTCCCT
ACATTATCAGCTTTATTCTAGTAGGGATTCCGGTTTGTATCACGGAATGGATTATGGGTAGAATGGGAGGTCGCACCGGT
CATAGTGCTCCTTTTTTATTTAAAAGTTTCCTTTCTGGCTTCCCCCTCAGAATCGTAGGGGCCATTGGGATTACAATTCC
TATTCTGATTTATGTATATTACGTTTTTATTGAAGCTTGGTGTCTTGCCTACTCCTTTGATTTTTTAACTGGACAAATTC
AATTCAATTCAAACGGTCAAGTTCCAGAATCTCAAATCATCCAAGCCGCCGGTAATTATTATCTAGATTTAACTGGAGCC
AGACACAACGGAGACGCAATTTCGAGTAAAATCTTTTATGCTACGATTACTTGTTTTATTCTCAATTTTGCCCTAGTCTT
TCGAGGAATTTCCAAAGGAATTGAAACCTTCGCAAAGATCGCGGTTCCTTTGATGTTAGTCTCTTCGATCATCATTCTAA
TTAGAGTCCTTACGTTAGACAACATTGATATAGGTCTCGGAAAGATGTGGAATCCGGATTGGTCTGCTCTTTTAAAATCA
GAAGTCTGGATTGCGGCGGCTGGTCAGGTATTTTTTACTTTATCCGCTGGTTTTGGAATCGCTCTTGTTTTTTCTAGCTA
TCTCAAACGAGATAACGACGTGGTTCTATCTTCTATTTCCGCTGCTTCTTTAAACGAATTCGTAGAAGTTGCCGTTGGAG
GTATGATTACAATTCCTGTCGCCTTTTTATTTTTAGGATCTTCGATCAATGATTTTGGTATGTTCGGAATGGGATTTATA
GCTCTTCCATCCGTTTTTTCTCTGATGCCAGGCGGTCAATGGTTCGGCGCCATTTGGTTCTTCGTTCTTTTTCTTGCAGC
GATCACTTCTTCAGTTACTATGTTACAACCAGGAATTATCTTTTTAGAAGAATCCTTCGGTCTGAAAAGAAAAACATCTT
GTCTAATTCTATTTTTATTTACCGCAAGCCTTTCTTTTCCAATTCTTTATTTCAATCAAAACTTTGAAGCCCTCGAACTC
GCAGATTTTTGGATCGGTACCATCTTGATTTTTATACTTGCAAGTATTCAAATTTTCTTATTCGGTTGGAAAATAGGCGC
TAAAAAAGGTTTAGAAGATGGTAATGAAGGTTCTCATTTAGAACTTCCTAAATTCTTTTGGTTTGTAATTCAATACATTA
CTCCCACATTTTTACTAGTCATATTCATAGCCTTCCTAATTCAAAACCTCCCCGGTCATTTTGAAAGAATGAGTATAGAT
TCTATGTTAGCTCAAGCGATTTCTAAAGGAACTTCCCTAGAAATCGCGCGTATGAAGGCCTTAGTTGCTAGATCTGTTTT
TTTTGGTATTTTATTAGTTTTTAGTTTGTTGGTTCTTCTAGTACACTATGCTTTGAAATATAAGGAAAAGAGAGTTCAAT
TAAAATGA

Upstream 100 bases:

>100_bases
CCCAACCCAATGCTGGAGCCGCCCACATGAAAATTTATGTCTCGTTTTTTACTCAACCCGCTCTGCTTTTCCTTTGACAG
AGAGGGGTTGAAAGTATGTT

Downstream 100 bases:

>100_bases
TGTTTTTAGCACAGGAAGGTTTAAACTGGCAAGGTATTTCTATCATGACTCTTTCTTTATTTTTAGTAACTGGTCTTTCC
ACGTTCTGCATTTTCAAACT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MQVNIMQKEAPKESWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTG
HSAPFLFKSFLSGFPLRIVGAIGITIPILIYVYYVFIEAWCLAYSFDFLTGQIQFNSNGQVPESQIIQAAGNYYLDLTGA
RHNGDAISSKIFYATITCFILNFALVFRGISKGIETFAKIAVPLMLVSSIIILIRVLTLDNIDIGLGKMWNPDWSALLKS
EVWIAAAGQVFFTLSAGFGIALVFSSYLKRDNDVVLSSISAASLNEFVEVAVGGMITIPVAFLFLGSSINDFGMFGMGFI
ALPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGIIFLEESFGLKRKTSCLILFLFTASLSFPILYFNQNFEALEL
ADFWIGTILIFILASIQIFLFGWKIGAKKGLEDGNEGSHLELPKFFWFVIQYITPTFLLVIFIAFLIQNLPGHFERMSID
SMLAQAISKGTSLEIARMKALVARSVFFGILLVFSLLVLLVHYALKYKEKRVQLK

Sequences:

>Translated_535_residues
MQVNIMQKEAPKESWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTG
HSAPFLFKSFLSGFPLRIVGAIGITIPILIYVYYVFIEAWCLAYSFDFLTGQIQFNSNGQVPESQIIQAAGNYYLDLTGA
RHNGDAISSKIFYATITCFILNFALVFRGISKGIETFAKIAVPLMLVSSIIILIRVLTLDNIDIGLGKMWNPDWSALLKS
EVWIAAAGQVFFTLSAGFGIALVFSSYLKRDNDVVLSSISAASLNEFVEVAVGGMITIPVAFLFLGSSINDFGMFGMGFI
ALPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGIIFLEESFGLKRKTSCLILFLFTASLSFPILYFNQNFEALEL
ADFWIGTILIFILASIQIFLFGWKIGAKKGLEDGNEGSHLELPKFFWFVIQYITPTFLLVIFIAFLIQNLPGHFERMSID
SMLAQAISKGTSLEIARMKALVARSVFFGILLVFSLLVLLVHYALKYKEKRVQLK
>Mature_535_residues
MQVNIMQKEAPKESWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTG
HSAPFLFKSFLSGFPLRIVGAIGITIPILIYVYYVFIEAWCLAYSFDFLTGQIQFNSNGQVPESQIIQAAGNYYLDLTGA
RHNGDAISSKIFYATITCFILNFALVFRGISKGIETFAKIAVPLMLVSSIIILIRVLTLDNIDIGLGKMWNPDWSALLKS
EVWIAAAGQVFFTLSAGFGIALVFSSYLKRDNDVVLSSISAASLNEFVEVAVGGMITIPVAFLFLGSSINDFGMFGMGFI
ALPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGIIFLEESFGLKRKTSCLILFLFTASLSFPILYFNQNFEALEL
ADFWIGTILIFILASIQIFLFGWKIGAKKGLEDGNEGSHLELPKFFWFVIQYITPTFLLVIFIAFLIQNLPGHFERMSID
SMLAQAISKGTSLEIARMKALVARSVFFGILLVFSLLVLLVHYALKYKEKRVQLK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507041, Length=504, Percent_Identity=24.8015873015873, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI289191351, Length=498, Percent_Identity=24.6987951807229, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4557046, Length=498, Percent_Identity=24.6987951807229, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI289191377, Length=498, Percent_Identity=24.6987951807229, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI4507043, Length=495, Percent_Identity=25.6565656565657, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI21361581, Length=538, Percent_Identity=23.7918215613383, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI194018524, Length=295, Percent_Identity=29.8305084745763, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI7657587, Length=509, Percent_Identity=24.950884086444, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI92859670, Length=521, Percent_Identity=23.0326295585413, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI58219014, Length=291, Percent_Identity=27.8350515463918, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI51468073, Length=301, Percent_Identity=27.5747508305648, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI134304856, Length=355, Percent_Identity=25.9154929577465, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI188528618, Length=392, Percent_Identity=24.7448979591837, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI33354281, Length=296, Percent_Identity=27.027027027027, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI197276623, Length=531, Percent_Identity=24.2937853107345, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI54607094, Length=531, Percent_Identity=24.2937853107345, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI11181770, Length=297, Percent_Identity=27.6094276094276, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI171184408, Length=509, Percent_Identity=23.7721021611002, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI171184406, Length=509, Percent_Identity=23.7721021611002, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI171184404, Length=509, Percent_Identity=23.7721021611002, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI6005715, Length=545, Percent_Identity=23.4862385321101, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI5032097, Length=361, Percent_Identity=24.6537396121884, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI67782317, Length=364, Percent_Identity=25.8241758241758, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI67782315, Length=359, Percent_Identity=26.1838440111421, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI67782313, Length=359, Percent_Identity=26.1838440111421, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI218563756, Length=356, Percent_Identity=24.7191011235955, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI289191353, Length=422, Percent_Identity=24.4075829383886, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI12408638, Length=292, Percent_Identity=24.3150684931507, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI197276625, Length=128, Percent_Identity=34.375, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25146584, Length=509, Percent_Identity=23.9685658153242, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17555248, Length=429, Percent_Identity=25.8741258741259, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71995588, Length=491, Percent_Identity=24.6435845213849, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17542050, Length=399, Percent_Identity=21.8045112781955, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133952791, Length=429, Percent_Identity=24.4755244755245, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554804, Length=471, Percent_Identity=21.8683651804671, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569475, Length=397, Percent_Identity=23.4256926952141, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535731, Length=389, Percent_Identity=23.3933161953728, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25143236, Length=470, Percent_Identity=24.2553191489362, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24762620, Length=484, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136952, Length=513, Percent_Identity=24.5614035087719, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24661428, Length=491, Percent_Identity=24.847250509165, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281364394, Length=513, Percent_Identity=24.5614035087719, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574704, Length=513, Percent_Identity=24.5614035087719, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136950, Length=513, Percent_Identity=24.5614035087719, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574702, Length=513, Percent_Identity=24.5614035087719, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19921936, Length=512, Percent_Identity=25.1953125, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24654186, Length=530, Percent_Identity=25.4716981132075, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24582567, Length=472, Percent_Identity=25.2118644067797, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221329674, Length=519, Percent_Identity=25.2408477842004, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639514, Length=519, Percent_Identity=25.2408477842004, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281363702, Length=504, Percent_Identity=25.9920634920635, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281365034, Length=520, Percent_Identity=23.8461538461538, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI45551088, Length=470, Percent_Identity=25.3191489361702, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24639516, Length=539, Percent_Identity=24.30426716141, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24652942, Length=470, Percent_Identity=25.3191489361702, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19921352, Length=524, Percent_Identity=23.4732824427481, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24584353, Length=524, Percent_Identity=23.4732824427481, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45550877, Length=531, Percent_Identity=24.8587570621469, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639853, Length=533, Percent_Identity=25.515947467167, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45551183, Length=405, Percent_Identity=25.9259259259259, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI281364136, Length=533, Percent_Identity=24.015009380863, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655079, Length=304, Percent_Identity=28.9473684210526, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281363700, Length=300, Percent_Identity=28, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24582569, Length=439, Percent_Identity=24.1457858769932, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 59037; Mature: 59037

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVNIMQKEAPKESWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFIL
CCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHCCCHHHCCCCCEEHHHHHHHHHH
VGIPVCITEWIMGRMGGRTGHSAPFLFKSFLSGFPLRIVGAIGITIPILIYVYYVFIEAW
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CLAYSFDFLTGQIQFNSNGQVPESQIIQAAGNYYLDLTGARHNGDAISSKIFYATITCFI
HHHHHHHHEEEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LNFALVFRGISKGIETFAKIAVPLMLVSSIIILIRVLTLDNIDIGLGKMWNPDWSALLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
EVWIAAAGQVFFTLSAGFGIALVFSSYLKRDNDVVLSSISAASLNEFVEVAVGGMITIPV
CHHEEECCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCCHHHHHH
AFLFLGSSINDFGMFGMGFIALPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGII
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEE
FLEESFGLKRKTSCLILFLFTASLSFPILYFNQNFEALELADFWIGTILIFILASIQIFL
EEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGWKIGAKKGLEDGNEGSHLELPKFFWFVIQYITPTFLLVIFIAFLIQNLPGHFERMSID
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SMLAQAISKGTSLEIARMKALVARSVFFGILLVFSLLVLLVHYALKYKEKRVQLK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVNIMQKEAPKESWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFIL
CCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHCCCHHHCCCCCEEHHHHHHHHHH
VGIPVCITEWIMGRMGGRTGHSAPFLFKSFLSGFPLRIVGAIGITIPILIYVYYVFIEAW
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CLAYSFDFLTGQIQFNSNGQVPESQIIQAAGNYYLDLTGARHNGDAISSKIFYATITCFI
HHHHHHHHEEEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LNFALVFRGISKGIETFAKIAVPLMLVSSIIILIRVLTLDNIDIGLGKMWNPDWSALLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
EVWIAAAGQVFFTLSAGFGIALVFSSYLKRDNDVVLSSISAASLNEFVEVAVGGMITIPV
CHHEEECCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCCHHHHHH
AFLFLGSSINDFGMFGMGFIALPSVFSLMPGGQWFGAIWFFVLFLAAITSSVTMLQPGII
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEE
FLEESFGLKRKTSCLILFLFTASLSFPILYFNQNFEALELADFWIGTILIFILASIQIFL
EEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGWKIGAKKGLEDGNEGSHLELPKFFWFVIQYITPTFLLVIFIAFLIQNLPGHFERMSID
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SMLAQAISKGTSLEIARMKALVARSVFFGILLVFSLLVLLVHYALKYKEKRVQLK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]