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The map label for this gene is glpD [H]

Identifier: 45657543

GI number: 45657543

Start: 2038703

End: 2040361

Strand: Direct

Name: glpD [H]

Synonym: LIC11675

Alternate gene names: 45657543

Gene position: 2038703-2040361 (Clockwise)

Preceding gene: 45657540

Following gene: 45657547

Centisome position: 47.66

GC content: 37.13

Gene sequence:

>1659_bases
ATGAATATGCCAACTAATAAAAAGTTATCTTCTTTAAAAACAAGATCATCTGGAAATTCAGAATCTTCCGTTTATGACTT
GTTAGTGATTGGAGGAGGAATTACGGGAGCACACGTGCTCTGGGATTCCACTTTGAGAGGAATGAAATCGATTCTTTTAG
AAAAAAACGATTACGCTTCTGGAACCAGCCAGGCGACGTCTAAAATGATTCATGGAGGGTTACGATATTTAAAAAATTTA
GAGCTGGGACTTGTCAGAGAATCTTTAAGAGAAAGGGCTACTTTGGCAAGAATTACACCACAAGCGGTTCAGACAATGGG
GATTTTGGTTCCACTCTATTCGAACTTGGATCGGATCGTTCTAAAGTTCGGAATGATTTTATATGACGCTCTTTCTTATG
ACCGAAACACAAATATATGTAAGGATAGATTGATTCCTAGATATGATTTTCTTTCTAAAGAACAAACACTTTTGGAATCT
CCTACAATCGAACGCGAAAAACTTAAAGGCGCTTACTTATATTACGATTATTTAAATATCAATCCAGAAAGACATACCTG
TGAATTTATCTTTTCCGCAAGGGAAAGAGGAGCAGAAGCAAAAAATTATACAGAAGTGGTTTCTATCACTCGTTCGAACA
ATTCCCTATACACAATCATTGCAAAAGATAGAATTTCAGGAAAGGAAATCGTATATAAAACTAGGGCAGTCATTAACGCG
GCGGGGCCTTGGGCGGATTTTATAGAATCTCTTGTAGGAGTTGAAATTGATAAACACCTTATCAGATCCAAGGGAATACA
CGTAGTTACCAGAAAGATAGGTGGGGATAAGATTTTAGTAACGAAAAAAAAAGACGGGACACATCTTTTTGTAATTCCTT
GGAGAAACAAAACGATTATTGGAACTACAGATACAGAATATGCGGATCATCCGGATCATTTTAGGGTTACTAAAAAAGAT
ATAGAAGAATTGTTAAGCGAAATCAACAATTCCTTTGGATATACAAATCTGACTTTGAAAGACGTGGATTTTTATTACGG
GGGTTTGAGACCTCTTGTAGAAGATTCGGGTGAGGGTGGATCTACATACAATACTTCCAGAAAGACAGAAATCATCGATC
ATAGAGATCTGGGTTTTCCAGGCTTTTTTACGGCTATGGGAGGGAAATATACAACGAGTCGTGGTGTAGCAGAAGAGGTC
GTCAATAAGGTAGCCGATTATCTTCCGGGAAATTTTCGAGTTTGTGAAACTTCGTCGGTTCCACCTTCTAGTGGAAATTA
TTCCGATCTTGTTTCGCTCATCAAGGATCTACAAAAAAAATTTGCTAAATTTAACGGAGAATTGATCGAGACGTTAGCAT
TTCGTTATGGATCTCAGTCGTATCGAATACTTGAAAAGAGTAAACCGGAAGAAGAATTTTATATTCTTCAAAATGGCGAA
AAATTTTACGAAAGTGAGGTAAAATTTATCACGAACAGAGAAGACATACGATTTGCGACTGATTTTTTCTTTCGTAGATC
TGGAGTGGGTGTGCCAGGTTTACTGGAAGAACAAGAAATGAATAGGCTTTTCAGATCCTTAGGAAGACATCTTGGTTGGA
ACCAGAATCAAATCCGTCAAGAAATCAAAACGGTAAAAGATCGTTATAAGATTTATTAG

Upstream 100 bases:

>100_bases
TTTTGAAACAAATCAAAAAAATAAATATCTTATATAAACCAACGATCGGATTCTTGCGCTTTTAAAATCGAAAGATCCGT
TTCATTTCTAAAAAATCGAG

Downstream 100 bases:

>100_bases
AAAATTAGAATGTAAATGAATTGGAAAGAAGGATTGATAAAAAATCTTTAACAACATCTGAAGTTTCCGAAAGACTAATC
GCCTCTGAGTCTAGAATTCT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MNMPTNKKLSSLKTRSSGNSESSVYDLLVIGGGITGAHVLWDSTLRGMKSILLEKNDYASGTSQATSKMIHGGLRYLKNL
ELGLVRESLRERATLARITPQAVQTMGILVPLYSNLDRIVLKFGMILYDALSYDRNTNICKDRLIPRYDFLSKEQTLLES
PTIEREKLKGAYLYYDYLNINPERHTCEFIFSARERGAEAKNYTEVVSITRSNNSLYTIIAKDRISGKEIVYKTRAVINA
AGPWADFIESLVGVEIDKHLIRSKGIHVVTRKIGGDKILVTKKKDGTHLFVIPWRNKTIIGTTDTEYADHPDHFRVTKKD
IEELLSEINNSFGYTNLTLKDVDFYYGGLRPLVEDSGEGGSTYNTSRKTEIIDHRDLGFPGFFTAMGGKYTTSRGVAEEV
VNKVADYLPGNFRVCETSSVPPSSGNYSDLVSLIKDLQKKFAKFNGELIETLAFRYGSQSYRILEKSKPEEEFYILQNGE
KFYESEVKFITNREDIRFATDFFFRRSGVGVPGLLEEQEMNRLFRSLGRHLGWNQNQIRQEIKTVKDRYKIY

Sequences:

>Translated_552_residues
MNMPTNKKLSSLKTRSSGNSESSVYDLLVIGGGITGAHVLWDSTLRGMKSILLEKNDYASGTSQATSKMIHGGLRYLKNL
ELGLVRESLRERATLARITPQAVQTMGILVPLYSNLDRIVLKFGMILYDALSYDRNTNICKDRLIPRYDFLSKEQTLLES
PTIEREKLKGAYLYYDYLNINPERHTCEFIFSARERGAEAKNYTEVVSITRSNNSLYTIIAKDRISGKEIVYKTRAVINA
AGPWADFIESLVGVEIDKHLIRSKGIHVVTRKIGGDKILVTKKKDGTHLFVIPWRNKTIIGTTDTEYADHPDHFRVTKKD
IEELLSEINNSFGYTNLTLKDVDFYYGGLRPLVEDSGEGGSTYNTSRKTEIIDHRDLGFPGFFTAMGGKYTTSRGVAEEV
VNKVADYLPGNFRVCETSSVPPSSGNYSDLVSLIKDLQKKFAKFNGELIETLAFRYGSQSYRILEKSKPEEEFYILQNGE
KFYESEVKFITNREDIRFATDFFFRRSGVGVPGLLEEQEMNRLFRSLGRHLGWNQNQIRQEIKTVKDRYKIY
>Mature_552_residues
MNMPTNKKLSSLKTRSSGNSESSVYDLLVIGGGITGAHVLWDSTLRGMKSILLEKNDYASGTSQATSKMIHGGLRYLKNL
ELGLVRESLRERATLARITPQAVQTMGILVPLYSNLDRIVLKFGMILYDALSYDRNTNICKDRLIPRYDFLSKEQTLLES
PTIEREKLKGAYLYYDYLNINPERHTCEFIFSARERGAEAKNYTEVVSITRSNNSLYTIIAKDRISGKEIVYKTRAVINA
AGPWADFIESLVGVEIDKHLIRSKGIHVVTRKIGGDKILVTKKKDGTHLFVIPWRNKTIIGTTDTEYADHPDHFRVTKKD
IEELLSEINNSFGYTNLTLKDVDFYYGGLRPLVEDSGEGGSTYNTSRKTEIIDHRDLGFPGFFTAMGGKYTTSRGVAEEV
VNKVADYLPGNFRVCETSSVPPSSGNYSDLVSLIKDLQKKFAKFNGELIETLAFRYGSQSYRILEKSKPEEEFYILQNGE
KFYESEVKFITNREDIRFATDFFFRRSGVGVPGLLEEQEMNRLFRSLGRHLGWNQNQIRQEIKTVKDRYKIY

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=572, Percent_Identity=27.972027972028, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI285002231, Length=572, Percent_Identity=27.972027972028, Blast_Score=202, Evalue=8e-52,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=29.0254237288136, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788574, Length=505, Percent_Identity=25.9405940594059, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=559, Percent_Identity=31.1270125223614, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17509253, Length=567, Percent_Identity=28.5714285714286, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322036, Length=581, Percent_Identity=27.0223752151463, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI161077125, Length=552, Percent_Identity=29.5289855072464, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24653942, Length=552, Percent_Identity=29.5289855072464, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24653944, Length=552, Percent_Identity=29.5289855072464, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI20130025, Length=552, Percent_Identity=29.5289855072464, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24586295, Length=551, Percent_Identity=24.3194192377495, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19921278, Length=293, Percent_Identity=28.6689419795222, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62872; Mature: 62872

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPTNKKLSSLKTRSSGNSESSVYDLLVIGGGITGAHVLWDSTLRGMKSILLEKNDYAS
CCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GTSQATSKMIHGGLRYLKNLELGLVRESLRERATLARITPQAVQTMGILVPLYSNLDRIV
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHH
LKFGMILYDALSYDRNTNICKDRLIPRYDFLSKEQTLLESPTIEREKLKGAYLYYDYLNI
HHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCCHHHHHHCCCCCCHHHCCCEEEEEEEEEC
NPERHTCEFIFSARERGAEAKNYTEVVSITRSNNSLYTIIAKDRISGKEIVYKTRAVINA
CCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCC
AGPWADFIESLVGVEIDKHLIRSKGIHVVTRKIGGDKILVTKKKDGTHLFVIPWRNKTII
CCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCEEE
GTTDTEYADHPDHFRVTKKDIEELLSEINNSFGYTNLTLKDVDFYYGGLRPLVEDSGEGG
ECCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCCCHHHHCCCCCC
STYNTSRKTEIIDHRDLGFPGFFTAMGGKYTTSRGVAEEVVNKVADYLPGNFRVCETSSV
CCCCCCCCCEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCC
PPSSGNYSDLVSLIKDLQKKFAKFNGELIETLAFRYGSQSYRILEKSKPEEEFYILQNGE
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEECCH
KFYESEVKFITNREDIRFATDFFFRRSGVGVPGLLEEQEMNRLFRSLGRHLGWNQNQIRQ
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
EIKTVKDRYKIY
HHHHHHHHHCCC
>Mature Secondary Structure
MNMPTNKKLSSLKTRSSGNSESSVYDLLVIGGGITGAHVLWDSTLRGMKSILLEKNDYAS
CCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GTSQATSKMIHGGLRYLKNLELGLVRESLRERATLARITPQAVQTMGILVPLYSNLDRIV
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHH
LKFGMILYDALSYDRNTNICKDRLIPRYDFLSKEQTLLESPTIEREKLKGAYLYYDYLNI
HHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCCHHHHHHCCCCCCHHHCCCEEEEEEEEEC
NPERHTCEFIFSARERGAEAKNYTEVVSITRSNNSLYTIIAKDRISGKEIVYKTRAVINA
CCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCC
AGPWADFIESLVGVEIDKHLIRSKGIHVVTRKIGGDKILVTKKKDGTHLFVIPWRNKTII
CCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCEEE
GTTDTEYADHPDHFRVTKKDIEELLSEINNSFGYTNLTLKDVDFYYGGLRPLVEDSGEGG
ECCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCCCHHHHCCCCCC
STYNTSRKTEIIDHRDLGFPGFFTAMGGKYTTSRGVAEEVVNKVADYLPGNFRVCETSSV
CCCCCCCCCEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCC
PPSSGNYSDLVSLIKDLQKKFAKFNGELIETLAFRYGSQSYRILEKSKPEEEFYILQNGE
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEECCH
KFYESEVKFITNREDIRFATDFFFRRSGVGVPGLLEEQEMNRLFRSLGRHLGWNQNQIRQ
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
EIKTVKDRYKIY
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]