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The map label for this gene is argB [H]

Identifier: 45657188

GI number: 45657188

Start: 1615359

End: 1616471

Strand: Reverse

Name: argB [H]

Synonym: LIC11308

Alternate gene names: 45657188

Gene position: 1616471-1615359 (Counterclockwise)

Preceding gene: 45657189

Following gene: 45657186

Centisome position: 37.79

GC content: 33.96

Gene sequence:

>1113_bases
ATGAATCATCAAGAAATTCTACTAAAACTTTTAGAAGTTACTGAGAATACTCAAGATTCGTTTCAGTTTTTAAAACGATT
TCGTTCCATCGAACCTGAAAAGTTTGCTGTGATCTATGCCGATTCCTCTACTCTGATGGAATCGGCAGAAGCTCTTCTTT
ATAATCTCAAACTACTTCACAAGTTAGATTTATTTCCAGTTGTAGTTTTGGATAAGGACGGAATTTCTTACACCAATCTA
TTTTATAGAAATCAAAACAAAGATGATACTCCCTCAATTTTACCTGGAAAATTATTCAGACATCCTCAGGATTTAGCGGG
TGCGGTTCGTTCCGCTTTAGATGAAGAAAAACTTCCTGTTTTTATAGCGGAAGAAAAAGGTCAGGTTCTTTTCAATTTTT
TAACTAAACTTTGTTCCATTCTTCGTACTAAAAAATTGGTTCATCTTTATTCCAGAGGTGGGGTTTATTTAAAAGGAAAT
AAAATTTCCATTTTCGACGTTGATTCCTCCATAAAACCGGATCCAGAAGACGAATCCATTTTATCTATCTGTTTAGAACT
TTATAAAAATGTAAAGGATAAGGATTTTGAAATCGCGATCACTTCTGCGTCTTCACTTCTCAAAGAATTATTTACAATCA
AAGGAAGTGGAACTCTTTTAAGAAGAAAGAACCGTATCGATTTTATTGAAGATCCTCTTACAGTTTCCAGTGAGAAGTTA
AATCTTTTGATCGAAAAGGCATTTCAAAAATCTCTTAAAAAAGATTTTTGGAATCAAAAGTTTGCCGGAATCCTTTTAGA
ATCTGAATTTAAAGGATGTGCGTTAGTAAAAAACACTTCTTTTGGTACGTTTCTATCTAAGTTTGCAGTAGATGAAATTG
CGAGGGGAGAAGGAGTTGGAAGAGACATTTGGGACGAACTAATCTATAGATTTCCAATTTTATTTTGGAGAGCAAGAAAA
GAAAATACGATTTCAAAATGGTATATGAAAGTATGCGACGGTATGCAAAAAGAAGGGATTTGGATTTACTTCTGGATCGG
AGTTCAAGAAATCCAAGTGCCTAATATTTGCTCTTTTCTCAAAAACCTCCCAGAAGATATGTCGAGCACCTAA

Upstream 100 bases:

>100_bases
TCTAAAATTAAAAAAAGACAAAGAACAATCTCTAACGATTGGAAAGTTAAAAGGAAAATTAGTTGCCTACACTTTAGGTA
GATAATCCAATCGATTCGGA

Downstream 100 bases:

>100_bases
AATGCGACCCATAGAAAGTCATCACCAACCCCACAAGTTAATAGGATTTTAGAATCAGAAGACTCCCAAAGGCACATTTT
TCAAGTGTTCCGACAAGAAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNHQEILLKLLEVTENTQDSFQFLKRFRSIEPEKFAVIYADSSTLMESAEALLYNLKLLHKLDLFPVVVLDKDGISYTNL
FYRNQNKDDTPSILPGKLFRHPQDLAGAVRSALDEEKLPVFIAEEKGQVLFNFLTKLCSILRTKKLVHLYSRGGVYLKGN
KISIFDVDSSIKPDPEDESILSICLELYKNVKDKDFEIAITSASSLLKELFTIKGSGTLLRRKNRIDFIEDPLTVSSEKL
NLLIEKAFQKSLKKDFWNQKFAGILLESEFKGCALVKNTSFGTFLSKFAVDEIARGEGVGRDIWDELIYRFPILFWRARK
ENTISKWYMKVCDGMQKEGIWIYFWIGVQEIQVPNICSFLKNLPEDMSST

Sequences:

>Translated_370_residues
MNHQEILLKLLEVTENTQDSFQFLKRFRSIEPEKFAVIYADSSTLMESAEALLYNLKLLHKLDLFPVVVLDKDGISYTNL
FYRNQNKDDTPSILPGKLFRHPQDLAGAVRSALDEEKLPVFIAEEKGQVLFNFLTKLCSILRTKKLVHLYSRGGVYLKGN
KISIFDVDSSIKPDPEDESILSICLELYKNVKDKDFEIAITSASSLLKELFTIKGSGTLLRRKNRIDFIEDPLTVSSEKL
NLLIEKAFQKSLKKDFWNQKFAGILLESEFKGCALVKNTSFGTFLSKFAVDEIARGEGVGRDIWDELIYRFPILFWRARK
ENTISKWYMKVCDGMQKEGIWIYFWIGVQEIQVPNICSFLKNLPEDMSST
>Mature_370_residues
MNHQEILLKLLEVTENTQDSFQFLKRFRSIEPEKFAVIYADSSTLMESAEALLYNLKLLHKLDLFPVVVLDKDGISYTNL
FYRNQNKDDTPSILPGKLFRHPQDLAGAVRSALDEEKLPVFIAEEKGQVLFNFLTKLCSILRTKKLVHLYSRGGVYLKGN
KISIFDVDSSIKPDPEDESILSICLELYKNVKDKDFEIAITSASSLLKELFTIKGSGTLLRRKNRIDFIEDPLTVSSEKL
NLLIEKAFQKSLKKDFWNQKFAGILLESEFKGCALVKNTSFGTFLSKFAVDEIARGEGVGRDIWDELIYRFPILFWRARK
ENTISKWYMKVCDGMQKEGIWIYFWIGVQEIQVPNICSFLKNLPEDMSST

Specific function: Unknown

COG id: COG5630

COG function: function code E; Acetylglutamate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Homo sapiens, GI23308587, Length=382, Percent_Identity=24.869109947644, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011242
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR006855 [H]

Pfam domain/function: PF00696 AA_kinase; PF04768 DUF619 [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 42590; Mature: 42590

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHQEILLKLLEVTENTQDSFQFLKRFRSIEPEKFAVIYADSSTLMESAEALLYNLKLLH
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
KLDLFPVVVLDKDGISYTNLFYRNQNKDDTPSILPGKLFRHPQDLAGAVRSALDEEKLPV
HHCCCEEEEECCCCCCEEHEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCE
FIAEEKGQVLFNFLTKLCSILRTKKLVHLYSRGGVYLKGNKISIFDVDSSIKPDPEDESI
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCCCCHHHH
LSICLELYKNVKDKDFEIAITSASSLLKELFTIKGSGTLLRRKNRIDFIEDPLTVSSEKL
HHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHH
NLLIEKAFQKSLKKDFWNQKFAGILLESEFKGCALVKNTSFGTFLSKFAVDEIARGEGVG
HHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC
RDIWDELIYRFPILFWRARKENTISKWYMKVCDGMQKEGIWIYFWIGVQEIQVPNICSFL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECEEEECCCHHHHHH
KNLPEDMSST
HHCCHHHCCC
>Mature Secondary Structure
MNHQEILLKLLEVTENTQDSFQFLKRFRSIEPEKFAVIYADSSTLMESAEALLYNLKLLH
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
KLDLFPVVVLDKDGISYTNLFYRNQNKDDTPSILPGKLFRHPQDLAGAVRSALDEEKLPV
HHCCCEEEEECCCCCCEEHEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCE
FIAEEKGQVLFNFLTKLCSILRTKKLVHLYSRGGVYLKGNKISIFDVDSSIKPDPEDESI
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCCCCHHHH
LSICLELYKNVKDKDFEIAITSASSLLKELFTIKGSGTLLRRKNRIDFIEDPLTVSSEKL
HHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHH
NLLIEKAFQKSLKKDFWNQKFAGILLESEFKGCALVKNTSFGTFLSKFAVDEIARGEGVG
HHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC
RDIWDELIYRFPILFWRARKENTISKWYMKVCDGMQKEGIWIYFWIGVQEIQVPNICSFL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECEEEECCCHHHHHH
KNLPEDMSST
HHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]