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The map label for this gene is htrA2

Identifier: 45656995

GI number: 45656995

Start: 1372900

End: 1374237

Strand: Reverse

Name: htrA2

Synonym: LIC11111

Alternate gene names: NA

Gene position: 1374237-1372900 (Counterclockwise)

Preceding gene: 45656996

Following gene: 45656994

Centisome position: 32.13

GC content: 36.32

Gene sequence:

>1338_bases
ATGAAATTTTATTTTTTCAAAATCTTCGTTTTAGTCCTATGTAGTTTGACAATTTCGGTTCCTTTAAAAGCAGAAACGAT
TCTGGTTCACTTTAGAAAATTCTCTCATCAAAATCCTTGGCAAAAAGGTTCACACTATGAAAGAAAAGTTCCGGCAATTG
TAGCCGATCAGGATTTTTTACTCGCACTACTTCTTCCCGGAGAATTTCCTCTTTTTTCAGAAACTAATCCAGAAACAAAA
CCGGGAACCCGCCTGTATTTGTTCAAACACGATCCACAAACAGGGCTGGCTCTTTTTTCTCATAAAGGTAAATTTTCCAC
TAAAAGAAAATCCCATTTTGGAGACTCTAATCATTCCACTTGCTCCAAGTTTTTTCCAAAACAGGAATGGGGAAGTCCGG
ATCTTTCCAATTCAATTTTAAGAATGAGCAAAAGACCCGGACCGGAAGGAAACACTAGAAATTTTCTATATTCAAAAAAT
ATAATTTGCGGCTATACCGACGGACGTTGGAACATTCCCGCAGAATATCTTTATTTATTTCTTCGTTCTTCTTCCAATAA
TCCCATCGTCCATCCAGGATTTTCTTTTGATGACTCTCTTACAATTCCGGAAAAGAAATTCTACTTTCCAGATTCTTCTT
ATGGTGTAGTGGTTTCTGAAGTTTTTCCGGGAGTTGGACCAGCACACAATCTATTTCCAGGTGATGCGATCTATGCCATC
AACGGCGAAATTTTCACTCATCCTCCAAACAGACAGGAAGTATTTTCTAAAATCCTCATGAACCATCATCGTCTGGCGCT
TCCGGGAACCAATGTAACCCTCTCCGTTTTCAGAACGGGTAAAAGAAAAGAAATTACGTATTCTTTAAAAAGTTACACAG
AGGATTCTTTTTTTATTCCTTCTGATTCGGGAGCCTTATCTCCTCCGTATTTAATCAGTGGTGGACTTTTTTTTACGGAA
TTAACAGGCGCTTATTTAAAAGAATCCGGAGATCGATATAGGGAAAATTCGGATAAAAAACTTCTTTATCTTTATGAGTC
CTTTAACAAAAAAGTTCATCCTGAAAAAAATCGCCTCGTATTTATCAGTAGAGTGTTTCCAGATTCAGCAAACAAAGGAT
TTCACGATTTCCAAGATCAAATTTTAGAATCTGTAAATGATCAAACGGTTCGATCTCTTTCCGATCTCAAAGAAATTCTA
AATGGAAACCAAAAAGAATCGATTGTATTTCGATTTTCTGGAAATCGTATCGCTGTGTTTTCCAAAGAACAACTTCAAAG
TCTGAACCAGAAAATTCTCGTAAATTATAACTTGGATAAATTAGACAATTTACATTGA

Upstream 100 bases:

>100_bases
TAAAATTCAGAGGTGTAAACCTTCCTATCATTTTAGATCAAGATACGATCGATAAAATCAATATTCGTATTAAAAAACGC
TTCGACGTGGAGGCGGACGA

Downstream 100 bases:

>100_bases
TAATATCTTGACGGATCTATTCCGGAAATGTAATGTTTGACTCCTATGCGAATTCTTTTTTTAGACGATGAAGAAATGAT
CCGAGATTTGTTCCGAGAAA

Product: HtrA2

Products: NA

Alternate protein names: Serine Protease; Peptidase S1 And S6 Chymotrypsin/Hap

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKFYFFKIFVLVLCSLTISVPLKAETILVHFRKFSHQNPWQKGSHYERKVPAIVADQDFLLALLLPGEFPLFSETNPETK
PGTRLYLFKHDPQTGLALFSHKGKFSTKRKSHFGDSNHSTCSKFFPKQEWGSPDLSNSILRMSKRPGPEGNTRNFLYSKN
IICGYTDGRWNIPAEYLYLFLRSSSNNPIVHPGFSFDDSLTIPEKKFYFPDSSYGVVVSEVFPGVGPAHNLFPGDAIYAI
NGEIFTHPPNRQEVFSKILMNHHRLALPGTNVTLSVFRTGKRKEITYSLKSYTEDSFFIPSDSGALSPPYLISGGLFFTE
LTGAYLKESGDRYRENSDKKLLYLYESFNKKVHPEKNRLVFISRVFPDSANKGFHDFQDQILESVNDQTVRSLSDLKEIL
NGNQKESIVFRFSGNRIAVFSKEQLQSLNQKILVNYNLDKLDNLH

Sequences:

>Translated_445_residues
MKFYFFKIFVLVLCSLTISVPLKAETILVHFRKFSHQNPWQKGSHYERKVPAIVADQDFLLALLLPGEFPLFSETNPETK
PGTRLYLFKHDPQTGLALFSHKGKFSTKRKSHFGDSNHSTCSKFFPKQEWGSPDLSNSILRMSKRPGPEGNTRNFLYSKN
IICGYTDGRWNIPAEYLYLFLRSSSNNPIVHPGFSFDDSLTIPEKKFYFPDSSYGVVVSEVFPGVGPAHNLFPGDAIYAI
NGEIFTHPPNRQEVFSKILMNHHRLALPGTNVTLSVFRTGKRKEITYSLKSYTEDSFFIPSDSGALSPPYLISGGLFFTE
LTGAYLKESGDRYRENSDKKLLYLYESFNKKVHPEKNRLVFISRVFPDSANKGFHDFQDQILESVNDQTVRSLSDLKEIL
NGNQKESIVFRFSGNRIAVFSKEQLQSLNQKILVNYNLDKLDNLH
>Mature_445_residues
MKFYFFKIFVLVLCSLTISVPLKAETILVHFRKFSHQNPWQKGSHYERKVPAIVADQDFLLALLLPGEFPLFSETNPETK
PGTRLYLFKHDPQTGLALFSHKGKFSTKRKSHFGDSNHSTCSKFFPKQEWGSPDLSNSILRMSKRPGPEGNTRNFLYSKN
IICGYTDGRWNIPAEYLYLFLRSSSNNPIVHPGFSFDDSLTIPEKKFYFPDSSYGVVVSEVFPGVGPAHNLFPGDAIYAI
NGEIFTHPPNRQEVFSKILMNHHRLALPGTNVTLSVFRTGKRKEITYSLKSYTEDSFFIPSDSGALSPPYLISGGLFFTE
LTGAYLKESGDRYRENSDKKLLYLYESFNKKVHPEKNRLVFISRVFPDSANKGFHDFQDQILESVNDQTVRSLSDLKEIL
NGNQKESIVFRFSGNRIAVFSKEQLQSLNQKILVNYNLDKLDNLH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50878; Mature: 50878

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFYFFKIFVLVLCSLTISVPLKAETILVHFRKFSHQNPWQKGSHYERKVPAIVADQDFL
CEEHHHHHHHHHHHHHHHCCCCCHHHEEEEEHHHCCCCCCCCCCCCCCCCCEEEECCCEE
LALLLPGEFPLFSETNPETKPGTRLYLFKHDPQTGLALFSHKGKFSTKRKSHFGDSNHST
EEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHCCCCCCCH
CSKFFPKQEWGSPDLSNSILRMSKRPGPEGNTRNFLYSKNIICGYTDGRWNIPAEYLYLF
HHHCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCCCCCCCHHHEEEE
LRSSSNNPIVHPGFSFDDSLTIPEKKFYFPDSSYGVVVSEVFPGVGPAHNLFPGDAIYAI
EECCCCCCEEECCCCCCCCCCCCCCEEECCCCCCCEEHHHHCCCCCCCCCCCCCCEEEEE
NGEIFTHPPNRQEVFSKILMNHHRLALPGTNVTLSVFRTGKRKEITYSLKSYTEDSFFIP
CCEEEECCCCHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCEEEEEHHHCCCCCEEEC
SDSGALSPPYLISGGLFFTELTGAYLKESGDRYRENSDKKLLYLYESFNKKVHPEKNRLV
CCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCEE
FISRVFPDSANKGFHDFQDQILESVNDQTVRSLSDLKEILNGNQKESIVFRFSGNRIAVF
EEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEE
SKEQLQSLNQKILVNYNLDKLDNLH
EHHHHHCCCCEEEEEECHHHHCCCC
>Mature Secondary Structure
MKFYFFKIFVLVLCSLTISVPLKAETILVHFRKFSHQNPWQKGSHYERKVPAIVADQDFL
CEEHHHHHHHHHHHHHHHCCCCCHHHEEEEEHHHCCCCCCCCCCCCCCCCCEEEECCCEE
LALLLPGEFPLFSETNPETKPGTRLYLFKHDPQTGLALFSHKGKFSTKRKSHFGDSNHST
EEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHCCCCCCCH
CSKFFPKQEWGSPDLSNSILRMSKRPGPEGNTRNFLYSKNIICGYTDGRWNIPAEYLYLF
HHHCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCCCCCCCHHHEEEE
LRSSSNNPIVHPGFSFDDSLTIPEKKFYFPDSSYGVVVSEVFPGVGPAHNLFPGDAIYAI
EECCCCCCEEECCCCCCCCCCCCCCEEECCCCCCCEEHHHHCCCCCCCCCCCCCCEEEEE
NGEIFTHPPNRQEVFSKILMNHHRLALPGTNVTLSVFRTGKRKEITYSLKSYTEDSFFIP
CCEEEECCCCHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCEEEEEHHHCCCCCEEEC
SDSGALSPPYLISGGLFFTELTGAYLKESGDRYRENSDKKLLYLYESFNKKVHPEKNRLV
CCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCEE
FISRVFPDSANKGFHDFQDQILESVNDQTVRSLSDLKEILNGNQKESIVFRFSGNRIAVF
EEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEE
SKEQLQSLNQKILVNYNLDKLDNLH
EHHHHHCCCCEEEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA