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The map label for this gene is dctR [H]

Identifier: 45656994

GI number: 45656994

Start: 1371949

End: 1372863

Strand: Reverse

Name: dctR [H]

Synonym: LIC11110

Alternate gene names: 45656994

Gene position: 1372863-1371949 (Counterclockwise)

Preceding gene: 45656995

Following gene: 45656990

Centisome position: 32.1

GC content: 39.13

Gene sequence:

>915_bases
TTGACTCCTATGCGAATTCTTTTTTTAGACGATGAAGAAATGATCCGAGATTTGTTCCGAGAAATTTTTGGAACCATACA
CGATCTCACTTTAATCGGAAGTGCCGAAGAAGCTTTAGAAGTCTGTAAAGACAAAAGTTTCGACCTAATTATAACCGATG
TACGTCTTCCTAAAATGAGTGGAATCGATTTTATTTCCAGACTAAGAGATAAAGAAATCAACACTCCATTTATCGTAATT
ACCGGAAATCAGGATATAGAAATTTCCATCCGGGCGCTTCGGTTAGGTGCAGTGGATTTTTTTATCAAACCATTTAGAAT
GGACGCAATCCGTCATTCTCTTCAGAAATTCGAAAGCCTATTCATTTCCAGTCAAGAACTCATCAGTAAAAATCATTTTC
AATTGACTCATTCCAAACAAAATTTTGCGATCAAACCCAGTCTCAAAAACCTGAATCAATACGTGAATTTGGTCATGCGT
TCTATTTCTTTAACTCCTGGGATTCATACGGACGATATACTTTCCATTAAACTCGCCTTATACGAGTTACTCGGAAACGC
GATCGAACACGGTTTTGCCGGAATCAGTTACGAACACAAGGCAAGTCTTCTTTCCTCCGATGTGGACTACGTTGATCACG
TGGATAAAATCTGCGCTGATATAAACGAATGTGTTCTACTCGAAATTGGTTTTGAAGACCAAAAAGTTTACGTCTCTCTT
AAAGACCGAGGAGCTGGTTTTGATCCTTCTAAGGTTCCGGACCCGGTCACAGATCCTAACGCGAGTTATCTTTCGGGTAG
AGGAATTTTTTTAGCAAGAATGAACGTAGACGAACTCGTTTACAACGATATTGGCAACGAGGTAAGCTTTAGTAAAACCT
TAAAAAGGGCTAATTCAAAAGTGAACGCCAGCTGA

Upstream 100 bases:

>100_bases
TCAAAGTCTGAACCAGAAAATTCTCGTAAATTATAACTTGGATAAATTAGACAATTTACATTGATAATATCTTGACGGAT
CTATTCCGGAAATGTAATGT

Downstream 100 bases:

>100_bases
AAGATAAATCCTGGAATATTCCCGTTTTGGTTCGTCTACTTTCCATTCTTCGAAAAATAGCTTTTTCTCTTTCTGTGGAT
CTACATAAGCATAGGATAAG

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTPMRILFLDDEEMIRDLFREIFGTIHDLTLIGSAEEALEVCKDKSFDLIITDVRLPKMSGIDFISRLRDKEINTPFIVI
TGNQDIEISIRALRLGAVDFFIKPFRMDAIRHSLQKFESLFISSQELISKNHFQLTHSKQNFAIKPSLKNLNQYVNLVMR
SISLTPGIHTDDILSIKLALYELLGNAIEHGFAGISYEHKASLLSSDVDYVDHVDKICADINECVLLEIGFEDQKVYVSL
KDRGAGFDPSKVPDPVTDPNASYLSGRGIFLARMNVDELVYNDIGNEVSFSKTLKRANSKVNAS

Sequences:

>Translated_304_residues
MTPMRILFLDDEEMIRDLFREIFGTIHDLTLIGSAEEALEVCKDKSFDLIITDVRLPKMSGIDFISRLRDKEINTPFIVI
TGNQDIEISIRALRLGAVDFFIKPFRMDAIRHSLQKFESLFISSQELISKNHFQLTHSKQNFAIKPSLKNLNQYVNLVMR
SISLTPGIHTDDILSIKLALYELLGNAIEHGFAGISYEHKASLLSSDVDYVDHVDKICADINECVLLEIGFEDQKVYVSL
KDRGAGFDPSKVPDPVTDPNASYLSGRGIFLARMNVDELVYNDIGNEVSFSKTLKRANSKVNAS
>Mature_303_residues
TPMRILFLDDEEMIRDLFREIFGTIHDLTLIGSAEEALEVCKDKSFDLIITDVRLPKMSGIDFISRLRDKEINTPFIVIT
GNQDIEISIRALRLGAVDFFIKPFRMDAIRHSLQKFESLFISSQELISKNHFQLTHSKQNFAIKPSLKNLNQYVNLVMRS
ISLTPGIHTDDILSIKLALYELLGNAIEHGFAGISYEHKASLLSSDVDYVDHVDKICADINECVLLEIGFEDQKVYVSLK
DRGAGFDPSKVPDPVTDPNASYLSGRGIFLARMNVDELVYNDIGNEVSFSKTLKRANSKVNAS

Specific function: Member of the two-component regulatory system dctS/dctR. Essential for expression of dctP [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=137, Percent_Identity=32.1167883211679, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=30.0970873786408, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788192, Length=109, Percent_Identity=33.0275229357798, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001034
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08220 HTH_DeoR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 34292; Mature: 34161

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPMRILFLDDEEMIRDLFREIFGTIHDLTLIGSAEEALEVCKDKSFDLIITDVRLPKMS
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCCEEEEEEECCCCCC
GIDFISRLRDKEINTPFIVITGNQDIEISIRALRLGAVDFFIKPFRMDAIRHSLQKFESL
CHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
FISSQELISKNHFQLTHSKQNFAIKPSLKNLNQYVNLVMRSISLTPGIHTDDILSIKLAL
HCCHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YELLGNAIEHGFAGISYEHKASLLSSDVDYVDHVDKICADINECVLLEIGFEDQKVYVSL
HHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEE
KDRGAGFDPSKVPDPVTDPNASYLSGRGIFLARMNVDELVYNDIGNEVSFSKTLKRANSK
ECCCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCC
VNAS
CCCC
>Mature Secondary Structure 
TPMRILFLDDEEMIRDLFREIFGTIHDLTLIGSAEEALEVCKDKSFDLIITDVRLPKMS
CCEEEEEECCHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHCCCCCEEEEEEECCCCCC
GIDFISRLRDKEINTPFIVITGNQDIEISIRALRLGAVDFFIKPFRMDAIRHSLQKFESL
CHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
FISSQELISKNHFQLTHSKQNFAIKPSLKNLNQYVNLVMRSISLTPGIHTDDILSIKLAL
HCCHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YELLGNAIEHGFAGISYEHKASLLSSDVDYVDHVDKICADINECVLLEIGFEDQKVYVSL
HHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEE
KDRGAGFDPSKVPDPVTDPNASYLSGRGIFLARMNVDELVYNDIGNEVSFSKTLKRANSK
ECCCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCC
VNAS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9168601; 10708364 [H]